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Translational Medical Research Commons™
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Articles 1 - 30 of 245
Full-Text Articles in Translational Medical Research
Operative Versus Nonoperative Management For Diverticulitis Complicated By Abscess, Alix Bernholtz, Abbie R. Bauer
Operative Versus Nonoperative Management For Diverticulitis Complicated By Abscess, Alix Bernholtz, Abbie R. Bauer
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
You K, Bendl R, Taut C, et al. Randomized clinical trial of elective resection versus observation in diverticulitis with extraluminal air or abscess initially managed conservatively. Br J Surg. 2018;105(8):971-979. https://doi.org/10.1002/bjs.10868
for a patient with a recurrent diverticulitis complicated by abscess formation.
Buprenorphine For Pain Management Vs. Chronic Hydrocodone-Acetaminophen Therapy When Comorbidities Increase The Risk Of Opioid-Related Side Effects, Jessica Zhao, Doo Hee Kim
Buprenorphine For Pain Management Vs. Chronic Hydrocodone-Acetaminophen Therapy When Comorbidities Increase The Risk Of Opioid-Related Side Effects, Jessica Zhao, Doo Hee Kim
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Gordon A, Callaghan D, Spink D, et al. Buprenorphine transdermal system in adults with chronic low back pain: a randomized, double-blind, placebo-controlled crossover study, followed by an open-label extension phase. Clin Ther. 2010;32(5):844-860. https://doi.org/10.1016/j.clinthera.2010.04.018
for a patient on long-term opioid therapy with high risk factors for adverse effects.
Simplifying Treatment From Double-Inhaler To Single-Inhaler Triple Therapy In Patients With Chronic Obstructive Pulmonary Disease, Kelly Yang, Leah Warren
Simplifying Treatment From Double-Inhaler To Single-Inhaler Triple Therapy In Patients With Chronic Obstructive Pulmonary Disease, Kelly Yang, Leah Warren
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using
Ferguson GT, Brown N, Compton C, et al. Once-daily single-inhaler versus twice-daily multiple-inhaler triple therapy in patients with COPD: lung function and health status results from two replicate randomized controlled trials. Respir Res. 2020;21(1):131. https://doi.org/10.1186/s12931-020-01360-w
for a patient requesting a simplified therapeutic regimen with equal efficacy for chronic obstructive pulmonary disease (COPD) management.
Effects Of Chaplain Care On Coping With Cancer, Sarah Battiston, Scott L. Baughan
Effects Of Chaplain Care On Coping With Cancer, Sarah Battiston, Scott L. Baughan
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical case decision report using:
Piderman KM, Radecki CR, Jenkins SM, et al. Hearing and heeding the voices of those with advanced illnesses. Journal of Palliative Care. 2020;35(4):248-255. https://doi.org/10.1177/0825859720928623
for a patient having difficulty coping with cancer
Efficacy Of Observational Care Versus Antibiotic Therapy For Treatment Of Acute Uncomplicated Diverticulitis, Morgan Mooty, Abbie R. Bauer
Efficacy Of Observational Care Versus Antibiotic Therapy For Treatment Of Acute Uncomplicated Diverticulitis, Morgan Mooty, Abbie R. Bauer
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
van Dijk ST, Daniels L, Ünlü Ç, et al. Long-Term Effects of Omitting Antibiotics in Uncomplicated Acute Diverticulitis. Am J Gastroenterol. 2018;113(7):1045-1052. https://doi.org/10.1038/s41395-018-0030-y
for a patient with acute uncomplicated diverticulitis.
Radiofreqency Device As An Alternative Therapy For Refractory Nasal Valve Collapse, Sara Farooqui, Doo Hee Kim
Radiofreqency Device As An Alternative Therapy For Refractory Nasal Valve Collapse, Sara Farooqui, Doo Hee Kim
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using
Silvers SL, Rosenthal JN, McDuffie CM, Yen DM, Han JK. Temperature-controlled radiofrequency device treatment of the nasal valve for nasal airway obstruction: A randomized controlled trial. Int Forum Allergy Rhinol. 2021 Dec;11(12):1676-1684. http://doi.org/10.1002/alr.22861
for a patient with nasal valve collapse.
Safety And Cost Effectiveness Of Immediate Sequential Bilateral Cataracts Surgery, Miles Bowman, Abbie R. Bauer
Safety And Cost Effectiveness Of Immediate Sequential Bilateral Cataracts Surgery, Miles Bowman, Abbie R. Bauer
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Rush SW, Gerald AE, Smith JC, Rush AJ, Rush RB. Prospective analysis of outcomes and economic factors of same-day bilateral cataract surgery in the United States. Journal of Cataract and Refractive Surgery. 2015;41(4):732-739. https://doi.org/10.1016/j.jcrs.2014.07.034
for a patient with bilateral cataracts.
Lack Of Alternatives To Colonoscopy Limits Care Of Patients Unable To Complete Bowel Preparation, Tala Al-Saghir
Lack Of Alternatives To Colonoscopy Limits Care Of Patients Unable To Complete Bowel Preparation, Tala Al-Saghir
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Benech N, Vinet O, Gaudin JL, et al.: The ONECC Study Group. Colon capsule endoscopy in clinical practice: lessons from a national 5-year observational prospective cohort. Endosc Int Open. 2021;9(10):E1542-E1548. https://doi.org/10.1055/a-1526-09231
for a patient with incomplete bowel preparation and colonoscopy.
Multiple Daily Injection Insulin Regimen Is An Effective, And More Economical, Alternative To Continuous Insulin Infusion For Type 1 Diabetics, Julia Yee
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Heller S, White D, Lee E, et al. A cluster randomised trial, cost-effectiveness analysis and psychosocial evaluation of insulin pump therapy compared with multiple injections during flexible intensive insulin therapy for type 1 diabetes: the REPOSE Trial. Health Technol Assess. 2017 Apr;21(20):1-278. https://doi.org/10.3310/hta21200
for a patient with type 1 diabetes.
Promoting Mammography Screenings In African American Women: Media, Church, And Health Providers, Lasonya Little, Debra C. Wallace, K.Jay Poole
Promoting Mammography Screenings In African American Women: Media, Church, And Health Providers, Lasonya Little, Debra C. Wallace, K.Jay Poole
Journal of Health Disparities Research and Practice
Due to the underutilization of screening mammography, African American women (AAW) are more likely to experience negative health outcomes after receiving a late-stage breast cancer diagnosis than White Women (WW). The purpose of this article is to examine the roles of the media, health community and the African American church and pastor and their potential impact in AAW screening decisions. Fifteen AAW, ages 45 and older, were invited to participate in a semi-structured interview. Most women agreed the African American pastor and church as well as the health community, and media are an integral part of their lives. Therefore, specific …
An American Medical Economics Phenomenon, Richard Guthmann Md, Mph
An American Medical Economics Phenomenon, Richard Guthmann Md, Mph
Clinical Research in Practice: The Journal of Team Hippocrates
The author reflects on his own experience with medical economics-driven phenomena in healthcare.
Social Determinants May Limit The Success Of Pcsk9 Inhibitors, An Effective Treatment For Hyperlipidemia In Statin-Intolerant Patients, Abigail C. Kuplicki
Social Determinants May Limit The Success Of Pcsk9 Inhibitors, An Effective Treatment For Hyperlipidemia In Statin-Intolerant Patients, Abigail C. Kuplicki
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Moriarty PM, Thompson PD, Cannon CP, et al. Efficacy and safety of alirocumab vs ezetimibe in statin-intolerant patients, with a statin rechallenge arm: The ODYSSEY ALTERNATIVE randomized trial. J. Clin. Lipidol. 2015;9(6):758-769. https://doi.org/10.1016/j.jacl.2015.08.006
for a statin-intolerant patient with hyperlipidemia.
Renal Disease Rehabilitation And Delaying Dialysis, Spencer Brown, Natalie Sterner
Renal Disease Rehabilitation And Delaying Dialysis, Spencer Brown, Natalie Sterner
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Greenwood SA, Koufaki P, Mercer TH, et al. Effect of exercise training on estimated GFR, vascular health, and cardiorespiratory fitness in patients with CKD: a pilot randomized controlled trial. Am J Kidney Dis. 2015;65(3):425-434. https://doi.org/10.1053/j.ajkd.2014.07.015
for a patient with non-dialysis CKD interested in slowing the progression toward necessary dialysis.
Slow Surgical Correction Affects More Than Just The Bowels, Emilia M. Clementi
Slow Surgical Correction Affects More Than Just The Bowels, Emilia M. Clementi
Clinical Research in Practice: The Journal of Team Hippocrates
Reflection on how delayed colostomy reversal affects a patient's mental and physical well-being.
Uptitrating Mycophenolate Mofetil Therapy In A Patient With Lupus Cerebritis Doesn’T Increase Risk Of Infection Compared To Cyclophosphamide, Gautham Pavar
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report appraising
Appel GB, Contreras G, Dooley MA, et al. Mycophenolate mofetil versus cyclophosphamide for induction treatment of lupus nephritis. J Am Soc Nephrol. 2009;20(5):1103-1112. https://doi.org/10.1681/ASN.2008101028
for a patient with neuropsychiatric lupus.
Stigma And Patient-Controlled Analgesia: Trust Is The Essential Ingredient Of Successful Patient Education In The Patient-Doctor Relationship, Trey D. Vanaken
Stigma And Patient-Controlled Analgesia: Trust Is The Essential Ingredient Of Successful Patient Education In The Patient-Doctor Relationship, Trey D. Vanaken
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Van Beers EJ, Van Tuijn CFJ, Nieuwkerk PT, et al. Patient-controlled analgesia versus continuous infusion of morphine during vaso-occlusive crisis in sickle cell disease, a randomized controlled trial. Am J Hematol. 2007;82(11):955-960. https://doi.org/10.1002/ajh.20944.
for a patient with recurrent vaso-occlusive crisis secondary to Sickle Cell Disease.
Early Closure Of Colostomy From Abdominal Trauma May Be Beneficial In Otherwise Healthy Patients, Nicole Xu
Early Closure Of Colostomy From Abdominal Trauma May Be Beneficial In Otherwise Healthy Patients, Nicole Xu
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report appraising
Khalid MS, Moeen S, Khan AW, Arshad R, Khan AF. Same admission colostomy closure: a prospective, randomised study in selected patient groups. Surgeon. 2005;3(1):11-14. https://doi.org/10.1016/s1479-666x(05)80004-6
for a patient with loop transverse colostomy due to trauma
Evaluating The Use Of Cheaper, Less Effective Medications In Patients With Cost-Based Medication Nonadherence, Muneer F. Hasso
Evaluating The Use Of Cheaper, Less Effective Medications In Patients With Cost-Based Medication Nonadherence, Muneer F. Hasso
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Sangaralingham LR, Sangaralingham SJ, Shah ND, Yao X, Dunlay SM. Adoption of Sacubitril/Valsartan for the Management of Patients With Heart Failure. Circ Heart Fail. 2018;11(2):e004302. https://doi.org/10.1161/circheartfailure.117.004302
for a patient with low medication adherence rates due to the high out-of-pocket costs of newer medications.
Motivational Interviewing May Resolve Vaccine Hesitancy, Scott L. Baughan
Motivational Interviewing May Resolve Vaccine Hesitancy, Scott L. Baughan
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Gagneur A, Lemaître T, Gosselin V, et al. A postpartum vaccination promotion intervention using motivational interviewing techniques improves short-term vaccine coverage: PromoVac study. BMC public health. 2018;18(1):811. https://doi.org/10.1186/s12889-018-5724-y
for a juvenile patient with a caregiver who is skeptical about the safety of routine vaccinations.
Buprenorphine/Suboxone Is Safe In Pregnancy: Substance Use And Stigma In The Healthcare Professions, Blake S. Sanford
Buprenorphine/Suboxone Is Safe In Pregnancy: Substance Use And Stigma In The Healthcare Professions, Blake S. Sanford
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Mullins N, Galvin SL, Ramage M, et al. Buprenorphine and Naloxone Versus Buprenorphine for Opioid Use Disorder in Pregnancy: A Cohort Study. J Addict Med. 2020;14(3):185-192. https://doi.org/10.1097/ADM.0000000000000562
for a woman with opioid use disorder during pregnancy.
Flexner Report 3.0—Structurally Competent Healthcare, James Peter Meza
Flexner Report 3.0—Structurally Competent Healthcare, James Peter Meza
Clinical Research in Practice: The Journal of Team Hippocrates
The editor advocates to formalize the addition of “Medical Social Sciences” as a basic science in our Schools of Medicine and “Clinical Decision Science” as the corollary clinical practice discipline: a “Flexner Report 3.0."
Interpreting P Values In 2023, Jennifer K. Homa-Bonell
Interpreting P Values In 2023, Jennifer K. Homa-Bonell
Journal of Patient-Centered Research and Reviews
If recent experiences shared among the biostatistician community are indicative of a sea change in research, then a most-welcome culture shift in dialogue surrounding the proper use and interpretation of the P value, which measures statistical probability, is underway. This editorial strives to offer guidance for researchers who would like to incorporate more comprehensive reporting in their research, namely, a broader discussion that goes beyond looking at the P value by itself and includes effect size estimates, confidence intervals, and clinical implications when interpreting quantitative results. Another evolving development in clinical research is the preferred language when referring …
Building Up Cal Poly Global Brigades Student Group: Reflections On Designing And Implementing One Undergraduate-Led Community Info Session, Caroline Nicole Smith, Jafra D. Thomas
Building Up Cal Poly Global Brigades Student Group: Reflections On Designing And Implementing One Undergraduate-Led Community Info Session, Caroline Nicole Smith, Jafra D. Thomas
Kinesiology and Public Health
Intro: Global Brigades, an international non-profit organization, trains college students and other pre-professionals in community-based health promotion by mobilizing community service trips around the world, which are taught and led by local community groups. Cal Poly’s Global Brigades student group was founded in 2018, and thus far, they have carried out three annual, medically-focused brigades to Honduras (two in-person, one virtual).
Purpose: The aim of this report is to present the findings of one experiential senior project to promote Cal Poly’s Global Brigades student group[1] (conducted January to March 2023).
Methods: The student designed material for …
I Finally Understand How Applying The Fagan Nomogram Can Change Medical Decision-Making, David Salvatori, Do
I Finally Understand How Applying The Fagan Nomogram Can Change Medical Decision-Making, David Salvatori, Do
Clinical Research in Practice: The Journal of Team Hippocrates
The author reflects on the case that changed his opinion on the efficacy of the Fagan nomogram.
Implicit Bias And Stigma Theory In Clinical Practice: Developing “Habits Of Mind” For Clinical Inquiry, James Peter Meza
Implicit Bias And Stigma Theory In Clinical Practice: Developing “Habits Of Mind” For Clinical Inquiry, James Peter Meza
Clinical Research in Practice: The Journal of Team Hippocrates
The editor introduces a new article type in this issue, Translational Social Science, and reflects on the social theory required to perceive and counteract implicit bias.
Stigma Is A Very Real Part Of Clinical Practice, Aaron Rivkin
Stigma Is A Very Real Part Of Clinical Practice, Aaron Rivkin
Clinical Research in Practice: The Journal of Team Hippocrates
The author reflects on avoiding stigmatizing language in clinical practice.
Advancing Health Equity In The Us Military, James D. Mancuso, John Young, Jennifer Rusiecki, Shauna Stahlman, Natasha Schvey, Toya Randolph, Candy Wilson, Catherine Witkop, Patrick Hyde, Althea Green, Patcho Santiago, Donald Shell, Tracy Sbrocco
Advancing Health Equity In The Us Military, James D. Mancuso, John Young, Jennifer Rusiecki, Shauna Stahlman, Natasha Schvey, Toya Randolph, Candy Wilson, Catherine Witkop, Patrick Hyde, Althea Green, Patcho Santiago, Donald Shell, Tracy Sbrocco
Journal of Health Disparities Research and Practice
Eliminating health disparities and achieving health equity are central to US national health objectives and the Military Health System’s “quadruple aim,” which has readiness as its core aim. Because military service members enjoy universal eligibility for health care, it is sometimes assumed that health disparities do not exist in the Department of Defense (DoD). However, while some studies have shown that disparities have been attenuated or eliminated in the DoD, others suggest that significant disparities remain. Reasons these disparities may remain include that universal eligibility for care does not necessarily result in equal to access to care, and that equal …
Bioprosthetic Reoperative Aortic Valve Replacement In Patients Under 50, Aisha Kazeem
Bioprosthetic Reoperative Aortic Valve Replacement In Patients Under 50, Aisha Kazeem
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Chan V, Lam BK, Rubens FD, et al. Long-term evaluation of biological versus mechanical prosthesis use at reoperative aortic valve replacement. J Thorac Cardiovasc Surg. 2012;144(1):146-151. https://doi.org/10.1016/j.jtcvs.2011.08.041
for a patient considering reoperative aortic valve replacement.
Renal Replacement Therapy Could Be Initiated In Patients With Severe Aki, Regardless Of Age And Critical Condition, El Hussain Shamsa
Renal Replacement Therapy Could Be Initiated In Patients With Severe Aki, Regardless Of Age And Critical Condition, El Hussain Shamsa
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Meersch M, Küllmar M, Schmidt C, et al. Long-Term Clinical Outcomes after Early Initiation of RRT in Critically Ill Patients with AKI. J Am Soc Nephrol. Mar 2018;29(3):1011-1019. https://doi.org/10.1681/asn.2017060694
for a critically ill elderly patient with severe acute kidney injury.
The Effect Of Medical Respite Services On Hospital Readmissions For Those Experiencing Homelessness, Kendrick Belardo
The Effect Of Medical Respite Services On Hospital Readmissions For Those Experiencing Homelessness, Kendrick Belardo
Clinical Research in Practice: The Journal of Team Hippocrates
A clinical decision report using:
Kertesz SG, Posner MA, O’Connell JJ, et al. Post-Hospital Medical Respite Care and Hospital Readmission of Homeless Persons. J Prev Interv Community. 2009;37(2):129-142. https://doi.org/10.1080/10852350902735734
for a patient experiencing homelessness.