Sports Sciences Commons^™

Is There A Relationship Between Rapid Weight Changes And Self-Reported Injury In Combat Sports Athletes? A 14-Month Study Of 24 Combat Sports Events, Colin S. Doherty, Oliver R. Barley, Lauren V. Fortington

Research outputs 2022 to 2026

Objectives: To explore the potential association between rapid weight changes and self-reported injury status (presence or absence of injury) 7 days following competitive events among male and female combat sports competitors.

Design: A 14-month study of 24 events.

Methods: A weight management questionnaire was completed 1-day post-competition, and an injury questionnaire was completed 7 days post-competition. These online questionnaires provided data on body mass and injury status. Mixed effects logistic regression models were used to analyse the odds ratios of rapid weight change variables and their impact on athletes' self-reporting as injured or non-injured.

Results: There were 172 responses (155 …

Rapid Force Generation During Unilateral Isometric Hamstring Assessment: Reliability And Relationship To Maximal Force, N. J. Ripley, J. Fahey, M. Cuthbert, J. J. Mcmahon, Paul Comfort

Research outputs 2022 to 2026

Limited research has reported the reliability of rapid force generation characteristics during isometric assessments of the hamstrings. Therefore, the purpose of the present study was to determine the between-session reliability of rapid force generating characteristics of the hamstrings and relationship to maximal force production. Twenty-three female soccer players (age: 20.7 ± 4.7 years; height: 168.7 ± 5.9 cm; body mass: 64.4 ± 6.7 kg) performed three unilateral trials of the 90–90 isometric hamstring assessment, on two separate occasions, separated by 7 days. Peak force, force at 100- and 200 ms and average rate of force development (aRFD) over 100- and …

Effects Of A Daily, Home-Based, 5-Minute Eccentric Exercise Program On Physical Fitness, Body Composition, And Health In Sedentary Individuals, Benjamin J.C. Kirk, Georgios Mavropalias, Anthony J. Blazevich, Jodie L. Cochrane-Wilkie, Aus Molan, Kazunori Nosaka

Research outputs 2022 to 2026

Purpose: This study examined the effects of a 4-week home-based bodyweight eccentric exercise program, requiring just 5 min daily, on physical fitness, body composition, and both physical and mental health in sedentary individuals.

Methods: Twenty-two sedentary but healthy individuals (4 men, 18 women; 32–69 years) completed a two-week control period followed by a 4-week intervention. The intervention involved daily exercises consisting of 10 repetitions each of chair squats, chair reclines, wall push-ups, and heel drops, including progressions if necessary. Assessments included isometric mid-thigh pull (IMTP), handgrip (HG) strength, push-up and sit-up endurance, sit-and-reach (S&R) flexibility, 3-min step test (3ST), squat …

The Effect Of Fatigue On Climbing Fluidity And Hand Movements, Andrew Walsh, L. Seifert, C. Button, S. Vial, J. Croft

Research outputs 2022 to 2026

In rock climbing, climbers use their arms to regulate their posture on the wall, which can lead to localised muscle fatigue. Evidence shows fatigue is the primary cause of falls, but little is known about how fatigue specifically affects climbing rhythm and hand movements. The present study examined climbing fluidity and hand movements on an indoor climbing wall before and after a specific fatiguing protocol. Seventeen climbers completed three repetitions of a challenging climbing route (21 on Ewbank scale) with different levels of localised arm fatigue. Climbers’ movements were tracked using 3D motion capture, and their hand actions assessed using …

Investigating The Internal And External Load Associated With Umpiring Semi-Professional Australian Rules Football, Corey Wilson, Mark Scanlan, Colin S. Doherty, Oliver R. Barley

Research outputs 2022 to 2026

Background: This investigation examined internal and external load associated with umpiring semi-professional Australian Rules football, an area of limited research. Objective: This exploratory quantitative study recruited 39 field umpires (Age: 25.2 ± 6.8 y, Body Mass: 74.6 ± 7.9 kg, Height: 178.9 ± 7.4 cm) from the Western Australian Football League (WAFL). Each participant was assessed in one match only. Methodology: External measures (total distance [TD], floating distance [FSD], high-intensity running distance [HSD]) and internal measures (blood lactate [BLa], heart rate [HR], rating of perceived exertion [RPE]) were collected during 22 matches, of the 2023 WAFL season. Data collection was …

Effect Of 6-Week Single Leg Countermovement Jump Training On Force Time Metrics In Elite Female Youth Footballers, Jack T. Fahey, Paul Comfort, Paul Jones, Nicholas, J. Ripley

Research outputs 2022 to 2026

Female football participation has grown exponentially. Unfortunately, females exhibit greater injury risk than male athletes, and experience increased mechanical stress during adolescence. Force plates provide accurate and reliable force-time characteristics enabling profiling of injury risk and benchmarking using a variety of jump and isometric tasks. The purpose of this study was to determine whether test-retest reliability and force-time characteristics of SLCMJ, bilateral countermovement jump (CMJ), countermovement rebound jump (CMJ-R) and isometric mid-thigh pull (IMTP) change with six weeks of SLCMJ training. Twenty-eight elite youth female footballers (13.7 ± 1.1 years, 53.27 ± 8.82 kg, 162.20 ± 5.37 cm) completed six …

Train Less And Still Similarly Improve? Maturational Growth Is More Influential Than Training Engagement On Performance Indices Development In Volleyball, Stephen Cobley, Marie Javet, Shaun Abbott, Caitlin Fox-Harding, Stephen Bested, Daniel Hackett, Michael Romann

Research outputs 2022 to 2026

Identifying factors which more or less account for performance improvement during developmental stages is essential for sports science knowledge and coaching practice. Accordingly, this study examined the longitudinal, changing, influences of Volleyball-specific Training Engagement (VTE) and Maturity Status on physical test performance development. Participants were N = 139 Swiss female competitive volleyball players, aged 10–14 years at baseline (M = 12.93, SD = 1.15 years). Annually for 3 years, participants completed the 9-3-6-3-9 Agility Sprint; Standing Long Jump [SLJ] and Jump & Reach test. Linear Mixed Models (LMMs) examined longitudinal independent and interactive relationships between VTE (hours/week) and Maturity Status …

The Anatomy Of Body Shaming In Sports Coaching, Valeria Varea, Robert S. Primus, Natalie Barker-Ruchti, Mikael Quennerstedt

Research outputs 2022 to 2026

Stories of body shaming in sports coaching are becoming widespread, and can intentionally, unintentionally, or inadvertently be used in different sports coaching practices. These practices do not necessarily intend to harm athletes. The aim of this paper is to explore body critical and body sensitive sport coaching practices that have the potential to be shaming, or as we call it in the title, the ‘anatomy’ of body shaming. The study used photo elicitation interviews including vignettes for data generation with 12 coaches from nine different sports. The results demonstrate that body criticality and body sensitivity function in different subtle ways …

The Effects Of Short-Term, Progressive Exercise Training On Disease Activity In Smouldering Multiple Myeloma And Monoclonal Gammopathy Of Undetermined Significance: A Single-Arm Pilot Study, A. Emery, S. Moore, J. Crowe, J. Murray, O. Peacock, D. Thompson, F. Betts, S. Rapps, L. Ross, D. Rothschild-Rodriguez, A. A. Echarri, R. Davies, R. Lewis, D. X. Augustine, A. Whiteway, Z. Afzal, J. L. J. Heaney, M. T. Drayson, J. E. Turner, John P. Campbell

Research outputs 2022 to 2026

Background: High levels of physical activity are associated with reduced risk of the blood cancer multiple myeloma (MM). MM is preceded by the asymptomatic stages of monoclonal gammopathy of undetermined significance (MGUS) and smouldering multiple myeloma (SMM) which are clinically managed by watchful waiting. A case study (N = 1) of a former elite athlete aged 44 years previously indicated that a multi-modal exercise programme reversed SMM disease activity. To build from this prior case study, the present pilot study firstly examined if short-term exercise training was feasible and safe for a group of MGUS and SMM patients, and secondly …

Downhill Running Does Not Alter Blood C1q Availability Or Complement-Dependent Cytotoxicity Of Therapeutic Monoclonal Antibodies Against Haematological Cancer Cell Lines In Vitro, Harrison D. Collier-Bain, Frankie F. Brown, Adam J. Causer, Lois Ross, Daniela Rothschild-Rodriguez, Noah Browne, Rachel Eddy, Kirstie L. Cleary, Juliet C. Gray, Mark S. Cragg, Sally Moore, James Murray, James E. Turner, John P. Campbell

Research outputs 2022 to 2026

Complement-dependent cytotoxicity (CDC) is a primary mechanism-of-action of monoclonal antibody (mAb) immunotherapies used to treat haematological cancers, including rituximab and daratumumab. However, mAb efficacy may be limited by reduced bioavailability of complement C1q – which activates the complement classical pathway following interactions with mAb-opsonised target cells. C1q is secreted by phagocytes upon recruitment to sites of muscle damage to facilitate muscular repair, hence we hypothesised that muscle damaging exercise may increase C1q ‘spill-over’ into blood. Additionally, other complement proteins (e.g., C1s) have been reported to increase following ultra-endurance and resistance exercise. Taken together, we hypothesised that muscle damaging exercise could …

Bibliometric Guide To Photographs Of Male Participants In Early Exercise And Physical Medicine Research, James L. Nuzzo

Research outputs 2022 to 2026

The history of exercise science research has undergone relatively little examination, and exercise science students receive little education about the field’s history. Photographs are tools that lecturers and writers can use to educate audiences about history. Yet, no resource exists that tells educators where they can find photographs of individuals participating in early studies about exercise or related topics (e.g., physical education, physical medicine). Here, the aim was to identify papers published before 1980 that contain photographs of boys and men participating in studies about exercise or related topics, aggregate the papers into a bibliometric list, and describe the photographs. …

An Exploratory Vector Field Analysis Of Ground Reaction Force During Maximum Sprinting Efforts In Male Soccer Players And Sprinters, Daniel Kadlec, Steffi Colyer, Ryu Nagahara, Sophia Nimphius

Research outputs 2022 to 2026

The ability to accelerate and attain high velocities is essential for both individual and team sport athletes. The purpose of this explorative study was to retrospectively analyze the ground reaction force using Statistical Parametric Mapping (SPM) vector field analysis, as traditional scalar analyses often fail to acknowledge the interdependence of force vector components. The ground reaction force vector and the scalar components (i.e., vertical and horizontal force) were analyzed for 28 male sprinters and 24 male soccer players at 8.0 and 8.5 m·s−1, and between 85%, 90%, 95%, and 100% of their maximum velocity. The ground reaction force vector differed …

Exercise Training Mode Effects On Myokine Expression In Healthy Adults: A Systematic Review With Meta-Analysis, Francesco Bettariga, Dennis R. Taaffe, Daniel A. Galvão, Pedro Lopez, Chris Bishop, Anna Maria Markarian, Valentina Natalucci, Jin Soo Kim, Robert U. Newton

Research outputs 2022 to 2026

Background: The benefits of exercise are well known; however, many of the underlying molecular mechanisms are not fully understood. Skeletal muscle secretes myokines, which mediate muscle–organ crosstalk. Myokines regulate satellite-cell proliferation and migration, inflammatory cascade, insulin secretion, angiogenesis, fatty oxidation, and cancer suppression. To date, the effects of different exercise modes (namely, aerobic and resistance exercise) on myokine response remain to be elucidated. This is crucial considering the clinical implementation of exercise to enhance general health and wellbeing and as a medical treatment. Methods: A systematic search was undertaken in PubMed, MEDLINE, CINAHL, Embase, SPORTDiscus, and Web of Science in …

Studying Contact Replays: Investigating Mechanisms, Management And Game Exposures (Scrimmage) For Brain Health In The Australasian National Rugby League: A Protocol For A Database Design, Andrew J. Gardner, Grant L. Iverson, Paul Bloomfield, Sharron Flahive, James Brown, Suzi Edwards, Gordon W. Fuller, Mazdak Ghajari, Prashant Jhala, Ben Jones, Christopher R. Levi, Warren Mcdonald, Shreya Mcleod, Cameron Owen, Georgia Page, Kenneth L. Quarrie, Oliver Smith, Peter Stanwell, Daniel Tadmor, Timana Tahu, Douglas P. Terry, Campbell Thomson, Ross Tucker, Lauren V. Fortington

Research outputs 2022 to 2026

Concussions in contact sports are challenging for athletes, health professionals and sporting bodies to prevent, detect and manage. Design of interventions for primary prevention, early recognition of concussion and continuing to improve postconcussion management are essential for protecting athletes and promoting brain health. Over the last decade, there have been advancements in video technology for analysing head impact events and improvements in the clinical management of concussions. This study protocol describes how researchers, clinicians and staff from the Australasian National Rugby League (NRL) have brought these advancements together and developed a database of videos with head impact events and clinical …

Relationship Between Hip And Groin Pain And Hip Range Of Motion In Amateur Soccer And Australian Rules Football Players, Andrea B. Mosler, Joshua J. Heerey, Joanne L. Kemp, Adam I. Semciw, Matthew G. King, Rintje Agricola, Peter R. Lawrenson, Mark J. Scholes, Benjamin F. Mentiplay, Kay M. Crossley

Research outputs 2022 to 2026

Background: The relationship between hip/groin pain and hip range of motion (ROM) is unclear. Purpose: To explore the relationship between hip/groin pain and hip joint ROM and examine the influence of sex and cam morphology on this relationship. Study Design: Cross-sectional study; Level of evidence, 3. Methods: Included were 184 amateur soccer and Australian Rules football players (276 hips; 20% women; median age, 26 years; interquartile range, 24-30 years) with hip/groin pain >6 months and a positive flexion-adduction-internal-rotation (FADIR) test, and 50 matched asymptomatic control players (98 hips; 28% women, median age, 26 years; interquartile range, 23-31 years). Hip ROM …

Rapid Weight Changes And Competitive Outcomes In Muay Thai And Mixed Martial Arts: A 14-Month Study Of 24 Combat Sports Events, Colin S. Doherty, Lauren V. Fortington, Oliver R. Barley

Research outputs 2022 to 2026

This study investigates the rapid weight loss (RWL) and rapid weight gain (RWG) of contest winners and losers from Muay Thai (MT) and mixed martial arts (MMA) events. The relationship between rapid weight change variables of males and females, and competitive success is also examined. Data from a weight management questionnaire was collected one day post-competition from 185 participants across 24 fight events, resulting in 263 responses (MMA: n = 78, MT: n = 185). Official and secondary weigh-in data were provided by the Combat Sports Commission. The results show that in MT, contest winners compared to losers had significantly …

Normative Data For The Squat, Bench Press And Deadlift Exercises In Powerlifting: Data From 809,986 Competition Entries, Daniel J. Van Den Hoek, Patrick L. Beaumont, Adele K. Van Den Hoek, Patrick J. Owen, Joel M. Garrett, Robert Buhmann, Christopher Latella

Research outputs 2022 to 2026

Objectives: Strength assessment and comparison to normative values are an important benchmarking tool in human health and performance. However, population specific normative data are several decades old, lack information about adolescent and adult strength levels and are not representative of the strength levels of strength trained individuals. The purpose of this study was to develop contemporary strength norms for the squat, bench press, and deadlift using powerlifters competing in un-equipped, drug-tested competitions. Design: Retrospective cross-sectional analysis. Methods: Retrospective data from global drug-tested, unequipped powerlifting competitions were collated with 809,986 samples (571,650 males, 238,336 females) included. Strength was assessed according to …

Performance Determinants And Evidence-Based Practice In Track Cycling: A Survey Of Coaches, Practitioners, And Athletes, Antony M.J. Stadnyk, Franco M. Impellizzeri, Jamie Stanley, Paolo Menaspà, Katie M. Slattery

Research outputs 2022 to 2026

Objectives: This study examined how track cycling coaches, practitioners, and athletes: develop knowledge and practices; value performance areas; and, implement research into practice. Design: Cross-sectional survey. Methods: An online REDCap survey of track cycling coaches, practitioners, and athletes was conducted involving questions related to demographics, performance area importance, knowledge acquisition and application, research relevance, and research direction. Results: A total of 159 responses were received from coaches (n = 55), practitioners (n = 29), and athletes (n = 75). Participants' highest track cycling competition level involvement ranged from local/regional (12.7%) to Olympic/Paralympic (39.9%). Respondents primarily develop practices by observing ‘the …

An Exploration Of Low Back Beliefs Of Male Pre-Professional And Professional Dancers, Isaac Campbell, Robyn Fary, Luke Hopper, Danica Hendry

Research outputs 2022 to 2026

Background: Globally, male dancers are affected by low back pain (LBP) up to 2.5 times more than female dancers. While female dancers’ beliefs around LBP and dance-specific low back movements exist, no research has explored male dancers’ beliefs. This study aimed to (1) examine the low back beliefs of Australian male professional and pre-professional dancers, and (2) determine if beliefs toward common low back movements and lifting differed when current LBP or history of disabling LBP (DLBP) were considered. Methods: 40 male dancers (mean age [SD] 26.9 years [7.9]) from a range of dance backgrounds (all participating in ballet) were …

Blood, Sweat, And Tears: Implications For Hydration Testing In Combat Sports—Investigating Body Mass Loss And Biomarker Changes, Colin S. Doherty, Lauren V. Fortington, Oliver R. Barley

Research outputs 2022 to 2026

Combat sports athletes often undergo rapid body mass loss (BML), which presents health risks. Hydration testing has been proposed as a possible solution to reduce or eliminate rapid BML. However, combat sports athletes may exhibit distinct physiological characteristics due to repeated exposure to BML. Thus, traditional and emerging hydration biomarkers should be investigated to determine their potential suitability for field use in this cohort. This study examined whether BML can explain changes in serum and urine osmolality (SosmΔ, UosmΔ), tear osmolarity (TosmΔ), hematocrit (HctΔ), and urine-specific gravity (USGΔ) after mild–moderate passive dehydration. Biomarker reliability was also assessed across two trials. …

Suppressive Effects Of Exercise-Conditioned Serum On Cancer Cells: A Narrative Review Of The Influence Of Exercise Mode, Volume, And Intensity, Francesco Bettariga, Dennis R. Taaffe, Daniel A. Galvão, Chris Bishop, Jin Soo Kim, Robert U. Newton

Research outputs 2022 to 2026

Cancer is a major cause of morbidity and mortality worldwide, and the incidence is increasing, highlighting the need for effective strategies to treat this disease. Exercise has emerged as fundamental therapeutic medicine in the management of cancer, associated with a lower risk of recurrence and increased survival. Several avenues of research demonstrate reduction in growth, proliferation, and increased apoptosis of cancer cells, including breast, prostate, colorectal, and lung cancer, when cultured by serum collected after exercise in vitro (i.e., the cultivation of cancer cell lines in an experimental setting, which simplifies the biological system and provides mechanistic insight into cell …

Identification Of Core Competencies For Exercise Oncology Professionals: A Delphi Study Of United States And Australian Participants, Mary A. Kennedy, Kelley Covington Wood, Anna Campbell, Melanie Potiaumpai, Christopher M. Wilson, Anna L. Schwartz, Jessica Gorzelitz, Maxime Caru, Kathryn H. Schmitz

Research outputs 2022 to 2026

Introduction: Integration of exercise into standard oncology care requires a highly skilled workforce of exercise professionals; however, competency requirements have not kept pace with advancements in the field. Therefore, the aim of this study was to obtain consensus on core competencies required for an exercise professional to be qualified to work with adults undergoing active cancer treatment. Materials and Methods: A three-round modified electronic Delphi process was used. In Round 1, an international group of 64 exercise oncology stakeholders (i.e., exercise oncology professionals (n = 29), clinical referrers (n = 21), and people with lived experience (n = 14)) responded …

Normalization Of Rapid Force To Peak Force In An Isometric Hamstring Assessment Using Force Plates, R. Barber, J. T. Fahey, P. Comfort, N. J. Ripley

Research outputs 2022 to 2026

Purpose: The aim of this investigation was to determine the reliability of normalizing rapid force (RF) production to peak force assessed during an isometric knee flexor assessment, and to present a novel method of classifying athletes' potential training needs within the 90–90 isometric hamstring assessment. Procedures: Twenty elite female soccer players (age: 20.7 ± 4.7 years; height: 168.2 ± 5.5 cm; body mass: 62.8 ± 7.0 kg), with no recent (>6 months) history of hamstring strain injury, volunteered to participate in the study. Following a standardized warm-up, each participant performed three maximal isometric hamstring contractions, with their heel resting …

Things To Keep In Mind When Selecting Physical Assessments In Youth Soccer: Correlations Between Test Performances, Interlimb Asymmetries, And Effects Of Maturation, Francisco Javier Robles-Palazón, John J. Mcmahon, Francisco Ayala, Paul Comfort

Research outputs 2022 to 2026

A range of field-based tests have been proposed for inclusion in physical performance assessment batteries. However, there are obvious time and human resources constraints in applied settings. The knowledge of potential relationships between tests on performance, asymmetries, as well as maturation-induced changes, may help select the most informative and least time-consuming testing battery. The purposes of this study were: (1) to determine correlations in performance between different field-based tests, in interlimb asymmetry between those unilateral tests, and between asymmetry scores and test performances, and (2) to determine the influence of players’ maturity status on test performances and asymmetries. A total …

Tendinopathy Severity Assessment–Achilles (Tendins-A): Evaluation Of Reliability And Validity In Accordance With Cosmin Recommendations, Myles C. Murphy, Fergus Mccleary, Dana Hince, Ruth Chimenti, Paola Chivers, J. Turner Vosseller, Sophia Nimphius, Nonhlanhla S. Mkumbuzi, Peter Malliaras, Nicola Maffulli, Robert J. De Vos, Ebonie K. Rio

Research outputs 2022 to 2026

Objective To evaluate the construct validity (structural validity and hypothesis testing), reliability (test–retest reliability, measurement error and internal consistency) and minimal important change (MIC) of the 13-item TENDINopathy Severity assessment–Achilles (TENDINS-A). Methods Participants with Achilles pain completed an online survey including: demographics, TENDINS-A, Foot and Ankle Outcome Score (FAOS) and Victorian Institute of Sport Assessment–Achilles (VISA-A). Exploratory factor analysis (EFA) assessed dimensionality. Confirmatory factor analysis (CFA) assessed structural validity (root mean square error of approximation (RMSEA); Comparative Fit Index (CFI); Tucker-Lewis Index (TLI); standardised root measure square (SRMS)). Correlations between TENDINS-A and the FAOS or VISA-A assessed hypothesis testing. Intraclass …

The Role Of Pennation Angle And Architectural Gearing To Rate Of Force Development In Dynamic And Isometric Muscle Contractions, Bas Van Hooren, Per Aagaard, Andrea Monte, Anthony J. Blazevich

Research outputs 2022 to 2026

Background: Associations between muscle architecture and rate of force development (RFD) have been largely studied during fixed-end (isometric) contractions. Fixed-end contractions may, however, limit muscle shape changes and thus alter the relationship between muscle architecture an RFD. Aim: We compared the correlation between muscle architecture and architectural gearing and knee extensor RFD when assessed during dynamic versus fixed-end contractions. Methods: Twenty-two recreationally active male runners performed dynamic knee extensions at constant acceleration (2000°s−2) and isometric contractions at a fixed knee joint angle (fixed-end contractions). Torque, RFD, vastus lateralis muscle thickness, and fascicle dynamics were compared during 0–75 and 75–150 ms …

Validity Of Apple Watch, Garmin Forerunner® 935 And Geneactiv For Estimating Energy Expenditure During Close Quarter Battle Training In Special Forces Soldiers, Angela Uphill, Kristina L. Kendall, Alison Fogarty, Stuart Guppy, Hannah Brown, Travis Zomer, Simon Parker, G. Gregory Haff

Research outputs 2022 to 2026

The purpose of this study was to investigate the validity of three wrist-worn devices for estimating energy expenditure (EE) and heart rate (HR) during close “Close Quarter Battle” (CQB). Fifty male soldiers (mean ± SD: age 30.9 ± 4.6 years, height: 1.81 ± 0.64 m and body mass 87.3 ± 7.7 kg) wore three activity monitors (Apple Watch 5, Garmin Forerunner® 935 and GENEActiv accelerometer), a Metamax 3B metabolic cart and a Polar chest strap, whilst conducting a CQB training activity (duration: 26.6 ± 5.0 min). EE and HR data from each test device were compared against criterion measures using …

Scs 6th Annual Meeting—Eevfa—11th International Congress Of Biochemistry And Physiology Of Exercise, Athens, Greece, 2023, Pedro E. Alcaraz, Elena Marín-Cascales, Anthony J. Blazevich, Tomás T. Freitas, Olyvia Donti, Konstantinos Spyrou, Gregory C. Bogdanis

Research outputs 2022 to 2026

On behalf of the Strength and Conditioning Society (SCS) and the Hellenic Society of Biochemistry and Exercise Physiology (EEVFA), we are pleased to present the abstracts of the SCS 6th Annual Meeting and EEVFA—11th International Congress of Biochemistry and Physiology of Exercise. The event was held at the Hellenic Olympic Committee headquarters in Athens, Greece, on 19–22 October 2023, and comprised several invited sessions from international and national speakers on a variety of topics related to biochemistry and exercise physiology, strength and conditioning practices and their application to health, injury prevention and sports performance. These included strength training in high-performance …

A Single Bout Of Vigorous Intensity Exercise Enhances The Efficacy Of Rituximab Against Human Chronic Lymphocytic Leukaemia B-Cells Ex Vivo, Harrison D. Collier-Bain, Annabelle Emery, Adam J. Causer, Frankie F. Brown, Rebecca Oliver, David Dutton, Josephine Crowe, Daniel Augustine, John Graby, Shoji Leach, Rachel Eddy, Daniela Rothschild-Rodriguez, Juliet C. Gray, Mark S. Cragg, Kirstie L. Cleary, Sally Moore, James Murray, James E. Turner, John P. Campbell

Research outputs 2022 to 2026

Chronic lymphocytic leukaemia (CLL) is characterised by the clonal proliferation and accumulation of mature B-cells and is often treated with rituximab, an anti-CD20 monoclonal antibody immunotherapy. Rituximab often fails to induce stringent disease eradication, due in part to failure of antibody-dependent cellular cytotoxicity (ADCC) which relies on natural killer (NK)-cells binding to rituximab-bound CD20 on B-cells. CLL cells are diffusely spread across lymphoid and other bodily tissues, and ADCC resistance in survival niches may be due to several factors including low NK-cell frequency and a suppressive stromal environment that promotes CLL cell survival. It is well established that exercise bouts …

Moderators Of Resistance Training Effects In Healthy Young Women: A Systematic Review And Meta-Analysis, Talita Molinari, Régis Radaelli, Anderson Rech, Clarissa M. Brusco, Anna M. Markarian, Pedro Lopez

Research outputs 2022 to 2026

Molinari, T, Radaelli, R, Rech, A, Brusco, CM, Markarian, AM, and Lopez, P. Moderators of resistance training effects in healthy young women: A systematic review and meta-analysis. J Strength Cond Res 38(4): 804-814, 2024 - To systematically review and analyze the effects of resistance-based exercise programs and potential moderators of change in body fat percentage, whole-body fat and lean mass, muscle hypertrophy, muscle strength, and muscle power/rapid force in healthy young women (between 18 and 35 years). A systematic search was undertaken in 7 databases from inception to May 2022. Eligible randomized controlled trials examined the effects of resistance-based exercise …