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Full-Text Articles in Sports Sciences

Impact Of Athletic Trainers On Coaches' Knowledge And Attitudes Of Concussions In Appalachia, Kylie Powell, Chad Starkey May 2018

Impact Of Athletic Trainers On Coaches' Knowledge And Attitudes Of Concussions In Appalachia, Kylie Powell, Chad Starkey

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

In Volume 4, Issue 1 of the JSMAHS you will find Professional research abstracts, as well as Under Graduate student research abstracts, case reports, and critically appraised topics.

Thank you for viewing this 4th Annual OATA Special Edition.


Evaluation Of Head Impact Exposure Between One Season Of Youth Versus High School Football, Kim D. Barber Foss, Christopher Dicesare, Jed A. Diekfuss, Weihong Yuan, Gregory D. Myer May 2018

Evaluation Of Head Impact Exposure Between One Season Of Youth Versus High School Football, Kim D. Barber Foss, Christopher Dicesare, Jed A. Diekfuss, Weihong Yuan, Gregory D. Myer

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

In Volume 4, Issue 1 of the JSMAHS you will find Professional research abstracts, as well as Under Graduate student research abstracts, case reports, and critically appraised topics.

Thank you for viewing this 4th Annual OATA Special Edition.


The "Mentorship Competency Assessment Of Research Mentors" Applied To Perceived Effectiveness Of Athletic Training Clinical Preceptors, Sara Stiltner, Matthew R. Kutz May 2018

The "Mentorship Competency Assessment Of Research Mentors" Applied To Perceived Effectiveness Of Athletic Training Clinical Preceptors, Sara Stiltner, Matthew R. Kutz

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

In Volume 4, Issue 1 of the JSMAHS you will find Professional Research Abstracts, as well as Bachelor and Master student research abstracts and case reports.

Thank you for viewing this 4th Annual OATA Special Edition.


Changes In Athletic Identity In High School Athletes Before And After Injury, Tara Handley, Laura L. Harris, Janet Simon May 2018

Changes In Athletic Identity In High School Athletes Before And After Injury, Tara Handley, Laura L. Harris, Janet Simon

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

In Volume 4, Issue 1 of the JSMAHS you will find Professional research abstracts, as well as Under Graduate student research abstracts, case reports, and critically appraised topics.

Thank you for viewing this 4th Annual OATA Special Edition.


Reliability Of A 2-Dimensional Running Gait Analysis, Shelley Payne Dr. May 2018

Reliability Of A 2-Dimensional Running Gait Analysis, Shelley Payne Dr.

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

In Volume 4, Issue 1 of the JSMAHS you will find Professional research abstracts, as well as Under Graduate student research abstracts, case reports, and critically appraised topics.

Thank you for viewing this 4th Annual OATA Special Edition.


Predictors Of Success On The Board Of Certification Exam, Andrea Cripps, Sara Stiltner, Elizabeth J. Walters, Adam Fullenkamp, Matt Laurent May 2018

Predictors Of Success On The Board Of Certification Exam, Andrea Cripps, Sara Stiltner, Elizabeth J. Walters, Adam Fullenkamp, Matt Laurent

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

In Volume 4, Issue 1 of the JSMAHS you will find Professional research abstracts, as well as Under Graduate student research abstracts, case reports, and critically appraised topics.

Thank you for viewing this 4th Annual OATA Special Edition.


This research is sponsored by an OATA Research Grant


Validity And Reliability Of The Ymca Submaximal Cycle Test Using An Electrically Braked Ergometer, Justin Kidd May 2018

Validity And Reliability Of The Ymca Submaximal Cycle Test Using An Electrically Braked Ergometer, Justin Kidd

Senior Honors Projects, 2010-2019

Purpose: To test the effect of using an electrically braked ergometer on the validity and reliability of the YMCA submaximal cycle test.

Methods: 22 male and 13 female subjects ages 19 to 31 completed one maximal treadmill test and four submaximal cycle tests to measure and estimate VO2max, respectively. The maximal tests involved recording heart rate and VO2 during graded exercise until volitional fatigue; an actual max was verified when two out of the following criteria: respiratory Exchange Ratio > 1.1, VO2 plateau (< 150 ml/min increase in VO2 during final stage), and achievement of 90% age-predicted HR max (or completed …


The Effects Of Dietary Nitrate Supplementation On Swimming Performance In Collegiate Swimmers 2018, Christopher Daniel Mosconi May 2018

The Effects Of Dietary Nitrate Supplementation On Swimming Performance In Collegiate Swimmers 2018, Christopher Daniel Mosconi

Master's Theses

The desire for performance enhancement is a common goal amongst athletes. Recently a number of studies have reported various performance enhancing effects of dietary nitrate (NO3-) via beetroot juice (BRJ) supplementation. Research has indicated that the various performance enhancing effects of BRJ can be attributed to a decrease resting systolic blood pressure (SBP), diastolic blood pressure (DBP), and submaximal volume of oxygen consumption (VO2), while increasing vasodilation and mitochondrial efficiency. Purpose: The purpose of this study was to investigate whether BRJ supplementation improves swimming performance in collegiate level swimmers. Methods: Eight collegiate trained swimmers underwent a double-blind 5-day chronic supplementation …


Aspects Of Weight Management In Ncaa Division Iii Collegiate Wrestlers 2018, Matthew Martone B.S., Cscs May 2018

Aspects Of Weight Management In Ncaa Division Iii Collegiate Wrestlers 2018, Matthew Martone B.S., Cscs

Master's Theses

Objective: The purpose of this study was to observe the weight management habits of division III collegiate wrestlers during the week leading up to a competition. Methods: Subjects reported to the lab on Monday morning after an overnight fast. Subjects were measured for height and weight and were asked to provide urine and blood samples for analysis of hydration and creatine kinase activity, respectively. Throughout the week, subjects were weighed in and out of practice to monitor daily weight fluctuations. Subjects also self-recorded all food and drink consumption throughout the 5-day period. On Saturday morning, approximately 1 hour before weigh-ins …


The Effects Of A Low Dose Of Caffeine On Bat Swing Performance In Fatigued And Non-Fatigued Female Softball Athletes 2018, Brianna Ferchen May 2018

The Effects Of A Low Dose Of Caffeine On Bat Swing Performance In Fatigued And Non-Fatigued Female Softball Athletes 2018, Brianna Ferchen

Master's Theses

Objective: The purpose of this study was to determine if caffeine ingestion decreased time to contact (TTC), and increased peak hand speed (HS), peak bat barrel speed (BS), and power (P) during a softball bat swing by fatigued and non-fatigued female athletes from an NCAA Division III varsity softball team. Methods: A randomized, single blind counterbalanced design was used to determine if 200 mg of caffeinated gum produced an ergogenic effect on nine female softball players (mean ± SD; age: 19.4 ± 0.7 yrs; height: 169 ± 6 cm; weight: 76.85 ± 10.82 kg) during a softball swing after chewing …


Effects Of Competition Variables And Prior Attempts On Approach Run Velocity During A Pole Vaulter's Final Clearance 2018, Nathaniel S. Ashton May 2018

Effects Of Competition Variables And Prior Attempts On Approach Run Velocity During A Pole Vaulter's Final Clearance 2018, Nathaniel S. Ashton

Master's Theses

Approach run velocity of a vaulter is strongly correlated to the highest height a vaulter clears in pole vault competition and the number of attempts taken throughout a competition influences pole vault strategy. Since approach run velocity greatly affects the crossbar height cleared and number of attempts affects time spent in the competition, perhaps a better approach to determine optimal competition strategy is to first identify how competition variables influence approach run velocity. The purpose of this study was to determine if the approach run velocity during a pole vaulter’s last clearance can be predicted by: (1) the number of …


The Relationship Between Stryd Power And Running Economy In Well-Trained Distance Runners 2018, Casey Austin May 2018

The Relationship Between Stryd Power And Running Economy In Well-Trained Distance Runners 2018, Casey Austin

Master's Theses

A novel running wearable called the Stryd Summit footpod attaches to a runner’s right or left shoe and measures running power output. The developers of the product purport that the footpod’s power and form power measures may correlate with metabolic data gathered in a lab. PURPOSE: Explore the relationship between power output and running economy at threshold pace. METHODS: Seventeen well-trained distance runners, 9 males and 8 females, completed a running protocol at threshold pace. Participants ran two discontinuous four-minute stages: one with their self-selected cadence (SS), and one with cadence lowered by 10% (LC). Metabolic data, power, and form …


Relationships Among Actual Motor Competence, Perceived Motor Competence And Health-Related Fitness In A College-Aged Population 2018, Samantha Moss May 2018

Relationships Among Actual Motor Competence, Perceived Motor Competence And Health-Related Fitness In A College-Aged Population 2018, Samantha Moss

Master's Theses

Purpose: The purpose of this study was to assess relationships among actual motor competence, perceived motor competence, and health-related fitness in a college-aged population. Methods: A total of 76 participants from SUNY Cortland enrolled in an undergraduate Kinesiology course completed an informed consent form. Total data were obtained on 71 participants (male = 53; female = 18). Perceived motor competence (PMC) was assessed via the Physical Self Perception Profile questionnaire, which participants completed one week prior to remaining assessments. Motor competence (MC) was assessed by maximum throw and kick speed as well as maximum distance jumped. Health-related fitness (HRF) was …


Neuromuscular Adaptations Following Training And Protein Supplementation In A Group Of Trained Weightlifters, Christopher B. Taber, Kevin Carroll, Brad H. Deweese, Kimitake Sato, Charles Stuart, Mary Howell, Kenton Hall, Caleb D. Bazyler, Michael H. Stone Apr 2018

Neuromuscular Adaptations Following Training And Protein Supplementation In A Group Of Trained Weightlifters, Christopher B. Taber, Kevin Carroll, Brad H. Deweese, Kimitake Sato, Charles Stuart, Mary Howell, Kenton Hall, Caleb D. Bazyler, Michael H. Stone

ETSU Faculty Works

The purpose of this study was to examine the effects of a recovery supplement compared with a placebo on muscle morphology in trained weightlifters. Vastus lateralis and muscle fiber cross sectional area of type I and type II fibers were compared between groups using a series of 2 × 2 (group × time) repeated measure ANOVAs. Both groups on average improved cross-sectional area of the vastus lateralis, type I and type II muscle fibers from pre-to-post but individual response varied within both groups. Greater magnitude of changes in type I and type II muscle fibers were observed for the placebo …


Comparing The Cost Effectiveness Of A Celiac Disease Panel To A Testing Cascade, Caleb Bazyler, Kevin Breuel Apr 2018

Comparing The Cost Effectiveness Of A Celiac Disease Panel To A Testing Cascade, Caleb Bazyler, Kevin Breuel

ETSU Faculty Works

Recent reductions in healthcare funding in the United States has pressured clinical laboratories to provide the same quality of diagnostic testing with fewer resources. Testing cascades have been developed to assist in the diagnosis of various illnesses, which use fewer tests and subsequently reduce costs. However, the cost effectiveness of a celiac disease (CD) testing cascade compared to a panel is currently unknown. Therefore, the purpose of this study was to determine if a CD testing cascade was equivalent to a panel in identifying patients deemed likely for CD, and to compare their cost effectiveness in a sample of symptomatic …


Pertinacity Volume 4 Issue 1, Courteney Benjamin Apr 2018

Pertinacity Volume 4 Issue 1, Courteney Benjamin

Pertinacity

No abstract provided.


Comparison Of Isokinetic Testing To Upper Extremity Closed Kinetic Chain Testing In Recreational College Athletes, Joe Bernardo Apr 2018

Comparison Of Isokinetic Testing To Upper Extremity Closed Kinetic Chain Testing In Recreational College Athletes, Joe Bernardo

Health Sciences Student Work

Background: Clinicians utilize various techniques during the rehabilitation process to ensure that patients can successfully recover from injury. Isokinetic testing and Closed Kinetic Chain testing have both been utilized during this process by various health care practitioners. Through the utilization of data gathered from these tests, clinicians can develop strengthening programs to target specific areas of weakness on the patient. However, there has not been extensive information in the literature regarding if the results from these two modalities correlate and share commonality with each other. Purpose: The purpose of this study is to discern whether data gathered from Isokinetic testing …


Patterns Of Social Skill Development Over-Time Among Clusters Of LifeSports Participants, Dawn Anderson-Butcher, Eric Martin, Lauren Paluta, Dan Gould Apr 2018

Patterns Of Social Skill Development Over-Time Among Clusters Of LifeSports Participants, Dawn Anderson-Butcher, Eric Martin, Lauren Paluta, Dan Gould

Kinesiology Faculty Publications and Presentations

Although growing in prevalence, little is known about how and for whom sport-based positive youth development (PYD) programs make a difference. This study addresses two gaps: A lack of multi-year studies and limited research differentiating outcomes between groups of participants. Specifically, this study uses repeated measures ANOVAs and hierarchical and non-hierarchical modeling procedures to investigate outcomes among two clusters of underserved youth who participated in two consecutive LiFEsports summer camps. Two hundred and thirty one youth participated, with the majority African American (87%) and male (62%). The average age of participants was 10.71 years. Participants completed surveys to assess …


Neuromuscular Adaptations Following Training And Protein Supplementation In A Group Of Trained Weightlifters, Christopher B. Taber, Kevin M. Carroll, Brad H. Deweese, Kimitake Sato, Charles A. Stuart, Mary Howell, Kenton Hall, Caleb Bazyler, Michael H. Stone Apr 2018

Neuromuscular Adaptations Following Training And Protein Supplementation In A Group Of Trained Weightlifters, Christopher B. Taber, Kevin M. Carroll, Brad H. Deweese, Kimitake Sato, Charles A. Stuart, Mary Howell, Kenton Hall, Caleb Bazyler, Michael H. Stone

Exercise Science Faculty Publications

The purpose of this study was to examine the effects of a recovery supplement compared with a placebo on muscle morphology in trained weightlifters. Vastus lateralis and muscle fiber cross sectional area of type I and type II fibers were compared between groups using a series of 2 × 2 (group × time) repeated measure ANOVAs. Both groups on average improved cross-sectional area of the vastus lateralis, type I and type II muscle fibers from pre-to-post but individual response varied within both groups. Greater magnitude of changes in type I and type II muscle fibers were observed for the placebo …


Concussion Competencies: A Framework For School-Based Concussion Management (Flyer), Arthur C. Maerlender, Jonathan Lichtenstein, Jennifer Parent-Nichols Feb 2018

Concussion Competencies: A Framework For School-Based Concussion Management (Flyer), Arthur C. Maerlender, Jonathan Lichtenstein, Jennifer Parent-Nichols

Center for Brain, Biology, and Behavior: Faculty Publications

This volume grew out of many years of clinical practice, research, and program projects. It is the culmination of more than 50 years of work with kids, brains, and schools. While there is research behind the Competencies and the underlying content, the intent was to create a user-friendly manual that cut across levels of responsibility and care. Concussion Competencies was not intended to be a textbook in the traditional manner; however, the Competencies have been shown to be a useful approach to teaching this material.

This volume is organized around a set of Competencies that have been shown to be …


Horse-Related Injuries: Causes, Preventability, And Where Educational Efforts Should Be Focused, Fernanda Camargo, William R. Gombeski Jr., Polly Barger, Connie Jehlik, Holly Wiemers, James Mead, Amy Lawyer Jan 2018

Horse-Related Injuries: Causes, Preventability, And Where Educational Efforts Should Be Focused, Fernanda Camargo, William R. Gombeski Jr., Polly Barger, Connie Jehlik, Holly Wiemers, James Mead, Amy Lawyer

Animal and Food Sciences Faculty Publications

A high percentage of equestrians will experience accidents, with different degrees of severity, throughout their riding careers. Horse-related injuries have the highest likelihood of requiring hospitalization based on individuals visiting US emergency departments. Studies have shown that the majority of injured riders said they could have prevented the accident and the injury was due to rider/handler error. Therefore, equestrians reported their injuries, and a panel of experts analyzed these reports to better understand the causes, how to prevent, and where to invest educational resources to generate a reduction in horse-related accidents. The majority of riders reported intermediate riding skills, most …


Resting Hormone Alterations And Injuries: Block Vs. Dup Weight-Training Among D-1 Track And Field Athletes, Keith B. Painter, G. Gregory Haff, N. Travis Triplett, Charles Stuart, Guy Hornsby, Mike W. Ramsey, Caleb D. Bazyler, Michael H. Stone Jan 2018

Resting Hormone Alterations And Injuries: Block Vs. Dup Weight-Training Among D-1 Track And Field Athletes, Keith B. Painter, G. Gregory Haff, N. Travis Triplett, Charles Stuart, Guy Hornsby, Mike W. Ramsey, Caleb D. Bazyler, Michael H. Stone

ETSU Faculty Works

Daily undulating periodization (DUP), using daily alterations in repetitions, has been advocated as a superior method of resistance training, while traditional forms of programming for periodization (Block) have been questioned. Nineteen Division I track and field athletes were assigned to either a 10-week Block or DUP training group. Year and event were controlled. Over the course of the study, there were four testing sessions, which were used to evaluate a variety of strength characteristics, including maximum isometric strength, rate of force development, and one repetition maximum (1RM). Although, performance trends favored the Block group for strength and rate of force …


Analytical Cpg Model Driven By Limb Velocity Input Generates Accurate Temporal Locomotor Dynamics, Sergiy Yakovenko, Anton Sobinov, Valeriya Gritsenko Jan 2018

Analytical Cpg Model Driven By Limb Velocity Input Generates Accurate Temporal Locomotor Dynamics, Sergiy Yakovenko, Anton Sobinov, Valeriya Gritsenko

Faculty & Staff Scholarship

The ability of vertebrates to generate rhythm within their spinal neural networks is essential for walking, running, and other rhythmic behaviors. The central pattern generator (CPG) network responsible for these behaviors is well-characterized with experimental and theoretical studies, and it can be formulated as a nonlinear dynam- ical system. The underlying mechanism responsible for locomotor behavior can be expressed as the process of leaky integration with resetting states generating appropriate phases for changing body velocity. The low-dimensional input to the CPG model generates the bilateral pattern of swing and stance modulation for each limb and is consistent with the desired …


Respiratory Muscle Training Positively Affects Vasomotor Response In Young Healthy Women, Angela Valentina Bisconti, Michela Devoto, Massimo Venturelli, Randall Bryner, Mark Olfert, Paul D. Chantler, F. Esposito Jan 2018

Respiratory Muscle Training Positively Affects Vasomotor Response In Young Healthy Women, Angela Valentina Bisconti, Michela Devoto, Massimo Venturelli, Randall Bryner, Mark Olfert, Paul D. Chantler, F. Esposito

Faculty & Staff Scholarship

Vasomotor response is related to the capacity of the vessel to maintain vascular tone within a narrow range. Two main control mechanisms are involved: the autonomic control of the sympathetic neural drive (global control) and the endothelial smooth cells capacity to respond to mechanical stress by releasing vasoactive factors (peripheral control). The aim of this study was to evaluate the effects of respiratory muscle training (RMT) on vasomotor response, assessed by flow-mediated dilation (FMD) and heart rate variability, in young healthy females. The hypothesis was that RMT could enhance the balance between sympa- thetic and parasympathetic neural drive and reduce …


Effects Of A 60 Minute On Ice Game Simulation On The Balance Error Scoring System, Philip Cameron, Noelle C. Sotero, Justin Byers Jan 2018

Effects Of A 60 Minute On Ice Game Simulation On The Balance Error Scoring System, Philip Cameron, Noelle C. Sotero, Justin Byers

Applied Health Sciences Student Works

Mild traumatic brain injuries (mTBIs) are common in contact sports. There is an association between mTBIs and altered motor function. BioSway technology measures individuals’ balance using the Balance Error Scoring System (BESS). Prior to incorporating BESS testing in concussion protocol, other variables that influence the BESS test require review. The objective of this study is to determine if game fatigue in hockey players also influences the BESS score. 23 male (21.08 ± 1.09) National Collegiate Athletic Association (NCAA) athletes were tested using the BioSway™ (Biodex, USA). The BESS test measures the Sway Index (SI) - a calculation of deviation from …


The Association Between The Coach-Athlete Relationship And Burnout Among High School Coaches, Scott Westfall, Eric M. Martin, Daniel Gould Jan 2018

The Association Between The Coach-Athlete Relationship And Burnout Among High School Coaches, Scott Westfall, Eric M. Martin, Daniel Gould

Kinesiology Faculty Publications and Presentations

Burnout is a term that continues to raise considerable concern among high school coaches and administrators (Raedeke, 1997) and has shown to have negative effects on coaches and athletes alike (Price & Weiss, 2000; Vealey, Armstrong, & Comar, 1998). While burnout has shown to have significant adverse effects, few studies have examined how the coach-athlete relationship may affect a coach s level of perceived burnout. This study sought to understand if the coach-athlete relationship predicted coach burnout. High school coaches (69 males, 62 females) completed the Coach-Athlete Relationship Questionnaire (CART-Q; Jowett & Ntoumanis, 2004), the Coaching Burnout Questionnaire, a modified …


Factor Structure And Gender Invariance Testing For The Sport Anxiety Scale-2 (Sas-2), Leilani Madrigal, Vincenzo Roma, Todd Caze, Arthur C. Maerlender, Debra Hope Jan 2018

Factor Structure And Gender Invariance Testing For The Sport Anxiety Scale-2 (Sas-2), Leilani Madrigal, Vincenzo Roma, Todd Caze, Arthur C. Maerlender, Debra Hope

Center for Brain, Biology, and Behavior: Faculty Publications

This study aimed to provide further psychometric validation of the Sport Anxiety Scale-2 (SAS-2) by assessing the factor structure, invariance across gender, and convergent and divergent validity of the SAS-2 by correlating both related (i.e., anxiety sensitivity, brief fear of negative evaluation, intolerance of uncertainty, and negative affect) and unrelated constructs (i.e., positive affect, self-confidence). A total of 542 current and former competitive athletes completed a questionnaire through Amazon’s Mechanical Turk system. All data were collected via online survey. Participants were randomly assigned to an exploratory factor analysis (n = 271) and confirmatory factor analysis group (n = 271). Results …


Accumulating Data To Optimally Predict Obesity Treatment (Adopt): Recommendations From The Biological Domain, Michael Rosenbaum, Tanya Agurs-Collins, Molly S. Bray, Kevin D. Hall, Mark Hopkins, Maren Laughlin, Paul S. Maclean, Padma Maruvada, Cary R. Savage, Dana M. Small, Luke Stoeckel Jan 2018

Accumulating Data To Optimally Predict Obesity Treatment (Adopt): Recommendations From The Biological Domain, Michael Rosenbaum, Tanya Agurs-Collins, Molly S. Bray, Kevin D. Hall, Mark Hopkins, Maren Laughlin, Paul S. Maclean, Padma Maruvada, Cary R. Savage, Dana M. Small, Luke Stoeckel

Center for Brain, Biology, and Behavior: Faculty Publications

Background: The responses to behavioral, pharmacological, or surgical obesity treatments are highly individualized. The Accumulating Data to Optimally Predict obesity Treatment (ADOPT) project provides a framework for how obesity researchers, working collectively, can generate the evidence base needed to guide the development of tailored, and potentially more effective, strategies for obesity treatment. Objectives: The objective of the ADOPT biological domain subgroup is to create a list of high-priority biological measures for weight-loss studies that will advance the understanding of individual variability in response to adult obesity treatments. This list includes measures of body composition, energy homeostasis (energy intake and output), …


Left Lateralized Cerebral Glucose Metabolism Declines In Amyloid-Β Positive Persons With Mild Cognitive Impairment, Christopher M. Weise, Kewei Chen, Yinghua Chen, Xiaoying Kuang, Cary R. Savage, Eric M. Reiman Jan 2018

Left Lateralized Cerebral Glucose Metabolism Declines In Amyloid-Β Positive Persons With Mild Cognitive Impairment, Christopher M. Weise, Kewei Chen, Yinghua Chen, Xiaoying Kuang, Cary R. Savage, Eric M. Reiman

Center for Brain, Biology, and Behavior: Faculty Publications

Background: Previous publications indicate that Alzheimer's Disease (AD) related cortical atrophy may develop in asymmetric patterns, with accentuation of the left hemisphere. Since fluorodeoxyglucose positron emission tomography (FDG PET) measurements of the regional cerebral metabolic rate of glucose (rCMRgl) provide a sensitive and specific marker of neurodegenerative disease progression, we sought to investigate the longitudinal pattern of rCMRgl in amyloid-positive persons with mild cognitive impairment (MCI) and dementia, hypothesizing asymmetric declines of cerebral glucose metabolism. Methods: Using florbetapir PET and cerebrospinal fluid (CSF) measures to define amyloid-β (Aβ) positivity, 40 Aβ negative (Aβ-) cognitively unimpaired controls (CU; 76 ± 5y), …


Novel Biomarkers Of Physical Activity Maintenance In Midlife Women: Preliminary Investigation, Kelly A. Bosak, Vlad B. Papa, Morgan G. Brucks, Cary R. Savage, Joseph E. Donnelly, Laura E. Martin Jan 2018

Novel Biomarkers Of Physical Activity Maintenance In Midlife Women: Preliminary Investigation, Kelly A. Bosak, Vlad B. Papa, Morgan G. Brucks, Cary R. Savage, Joseph E. Donnelly, Laura E. Martin

Center for Brain, Biology, and Behavior: Faculty Publications

The precision health initiative is leading the discovery of novel biomarkers as important indicators of biological processes or responses to behavior, such as physical activity. Neural biomarkers identified by magnetic resonance imaging (MRI) hold promise to inform future research, and ultimately, for transfer to the clinical setting to optimize health outcomes. This study investigated resting-state and functional brain biomarkers between midlife women who were maintaining physical activity in accordance with the current national guidelines and previously acquired age-matched sedentary controls. Approval was obtained from the Human Subjects Committee. Participants included nondiabetic, healthy weight to overweight (body mass index 19–29.9 kg/m …