Physiotherapy Commons^™

Lived Experiences Of American Adults Who Survive Covid-19: Implications For Physical Activity And Interpersonal Stress, Linda B. Piacentine, Hannah C. Barbosa, Kristin Haglund, Lauren Opielinski, Sandra K. Hunter, Paula E. Papanek, Marie K. Hoeger Bement, Norah L. Johnson

College of Nursing Faculty Research and Publications

Introduction: The cumulative number of COVID-19 cases has surpassed 579 million globally. Symptoms during and after COVID-19 infection vary from mild cold symptoms to severe multisystem illness. Given the wide range of symptom presentations and complications post COVID-19, the purpose of this study was to describe the lived experience of American adults surviving COVID-19.

Method: This study employed an exploratory qualitative description design. Semi-structured interviews were conducted with a sample of 35 individuals, [white (94%), female (71%), mean age = 43.7 years], with proximity to a university in an urban Midwest American city. Interviews occurred between May and …

Sex Differences In Human Fatigability: Mechanisms And Insight To Physiological Responses, Sandra K. Hunter

Exercise Science Faculty Research and Publications

Sex-related differences in physiology and anatomy are responsible for profound differences in neuromuscular performance and fatigability between men and women. Women are usually less fatigable than men for similar intensity isometric fatiguing contractions. This sex difference in fatigability, however, is task specific because different neuromuscular sites will be stressed when the requirements of the task are altered, and the stress on these sites can differ for men and women. Task variables that can alter the sex difference in fatigability include the type, intensity and speed of contraction, the muscle group assessed and the environmental conditions. Physiological mechanisms that are responsible …

Stressor-Induced Increase In Muscle Fatigability Of Young Men And Women Is Predicted By Strength But Not Voluntary Activation, Manda L. Keller-Ross, Hugo M. Pereira, Jaclyn Pruse, Tejin Yoon, Bonnie A. Schlinder-Delap, Kristy A. Nielson, Sandra K. Hunter

Psychology Faculty Research and Publications

This study investigated mechanisms for the stressor-induced changes in muscle fatigability in men and women. Participants performed an isometric-fatiguing contraction at 20% maximal voluntary contraction (MVC) until failure with the elbow flexor muscles. Study one (n = 55; 29 women) involved two experimental sessions: 1) a high-stressor session that required a difficult mental-math task before and during a fatiguing contraction and 2) a control session with no mental math. For some participants (n = 28; 14 women), cortical stimulation was used to examine mechanisms that contributed to muscle fatigability during the high-stressor and control sessions. Study two …

Atropine Microdialysis Within Or Near The Pre-Bötzinger Complex Increases Breathing Frequency More During Wakefulness Than During Nrem Sleep, Clarissa Muere, Suzanne E. Neumueller, Justin Robert Miller, Samantha Olesiak, Matthew R. Hodges, Lawrence Pan, Hubert V. Forster

Physical Therapy Faculty Research and Publications

Normal activity of neurons within the medullary ventral respiratory column (VRC) in or near the pre-Bötzinger Complex (preBötC) is dependent on the balance of inhibitory and excitatory neuromodulators acting at their respective receptors. The role of cholinergic neuromodulation during awake and sleep states is unknown. Accordingly, our objective herein was to test the hypotheses that attenuation of cholinergic modulation of VRC/preBötC neurons in vivo with atropine would: 1) decrease breathing frequency more while awake than during non-rapid-eye-movement (NREM) sleep and 2) increase other excitatory neuromodulators. To test these hypotheses, we unilaterally dialyzed mock cerebrospinal fluid (mCSF) or 50 mM atropine …

Changes In Neurochemicals Within The Ventrolateral Medullary Respiratory Column In Awake Goats After Carotid Body Denervation, Justin Robert Miller, Suzanne E. Neumueller, Clarissa Muere, Samantha Olesiak, Lawrence Pan, Matthew R. Hodges, Hubert V. Forster

Physical Therapy Faculty Research and Publications

A current and major unanswered question is why the highly sensitive central CO₂/H⁺ chemoreceptors do not prevent hypoventilation-induced hypercapnia following carotid body denervation (CBD). Because perturbations involving the carotid bodies affect central neuromodulator and/or neurotransmitter levels within the respiratory network, we tested the hypothesis that after CBD there is an increase in inhibitory and/or a decrease in excitatory neurochemicals within the ventrolateral medullary column (VMC) in awake goats. Microtubules for chronic use were implanted bilaterally in the VMC within or near the pre-Bötzinger Complex (preBötC) through which mock cerebrospinal fluid (mCSF) was dialyzed. Effluent mCSF was collected …

Effect Of Age On Hemodynamic And Metabolic Response To Static Exercise, Daniel J. Mcdermott, William J. Stekiel, Joseph J. Barboriak, Luther C. Kloth, James J. Smith

Physical Therapy Faculty Research and Publications

Static muscle exercise tests consisting of one-third maximum voluntary contraction of the forearm for 5 min was carried out in a group of older (mean age 46.8 yr) and younger men (mean age 25.3 yr). The mean hemodynamic changes in the two groups were quite comparable with increases in heart rate (31.3 and 38.4 beats/min), systolic pressure (74.3 and 63.2 mmHg), and diastolic pressure (58.1 and 47.3 mmHg) in older and younger groups, respectively. There was a prompt postexercise increase in mean total plasma catecholamine level in older males with a rapid decline over the next 15 min; the increase …