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Articles 31 - 60 of 232
Full-Text Articles in Rehabilitation and Therapy
Effects Of Taping On Motor Function Of Upper Extremity In Chronic Stroke Patients, Rong-Bin Hong, Yi-Ru Chen, Da-Fang Chan, Willy Chou, Jeng-Feng Yang
Effects Of Taping On Motor Function Of Upper Extremity In Chronic Stroke Patients, Rong-Bin Hong, Yi-Ru Chen, Da-Fang Chan, Willy Chou, Jeng-Feng Yang
Rehabilitation Practice and Science
The purpose of this study was to evaluate the effects of taping on motor recovery of paretic upper limb in chronic stroke patients. Ten chronic stroke patients with upper limb paresis were recruited. They all received regular rehabilitation programs before this study. Taping was applied to the upper trunk and paretic shoulder of those patients in addition to regular 3-week rehabilitation. Succeedingly, they received only regular rehabilitation for another 3 weeks. Three tests were conducted before and after taping and at 3 weeks follow-up. For each test, we measured the movement amplitudes of active shoulder flexion and abduction, Fugl-Meyer Motor …
Development Of Brain Abscess At The Exact Site Of A Previous Intracerebral Hematoma: A Casereport, Yi-Yen Chu, Shu-Huan Lin, Tyng-Guey Wang
Development Of Brain Abscess At The Exact Site Of A Previous Intracerebral Hematoma: A Casereport, Yi-Yen Chu, Shu-Huan Lin, Tyng-Guey Wang
Rehabilitation Practice and Science
Brain abscess is a neurological emergency that requires immediate high-dose antibiotics or surgical intervention. Brain abscess at the site of a previous hemorrhagic stroke that did not receive surgical intervention is rare. Here, we report the case of a 48-year-old man who developed a brain abscess as infective transformation of a preceding right putaminal hemorrhage, 22 days after the stroke. The patient recovered after surgical treatment and systemic antibiotics therapy. An abscess culture test revealed the presence of Group D Salmonella, which has never been reported in a case of brain abscess. A comprehensive literature reviewarticle was performed. We concluded …
Macrodystrophia Lipomatosa: A Casereport, Pai-Yin Chen, Shu-Min Chen, Chii-Jeng Lin
Macrodystrophia Lipomatosa: A Casereport, Pai-Yin Chen, Shu-Min Chen, Chii-Jeng Lin
Rehabilitation Practice and Science
Macrodystrophia lipomatosa is a rare congenital anomaly of localized gigantism, characterized by progressive overgrowth of all mesenchymal components, particularly fibroadipose tissue. The anomaly occurs frequently in the distribution regions of the median nerve in the upper extremity and the plantar nerve in the lower extremity. It is usually noticed at birth with predominately unilateral distal involvement of the digits. The cause of this condition is still unknown. Physicians use the patient's clinical history, physical examination, and imaging techniques to diagnose the condition, with characteristic imaging findings revealing macrodactyly with hypertrophy of the soft tissue and osseous structures. This study reports …
Decreasing The Incidence Of Skin Damage Caused By Physical Agents, Mei-Chu Chen, Der-Sheng Han
Decreasing The Incidence Of Skin Damage Caused By Physical Agents, Mei-Chu Chen, Der-Sheng Han
Rehabilitation Practice and Science
Physical therapists play a crucial role in preventing skin damage, the causes of which are usually due to improper machine settings and a failure to adhere to standard operation procedures during treatments involving physical agents. To decrease incidents, this study examines the causes of skin damage, and drafting intervention and evaluation index.This paper analyzed 12 cases of skin damage occurring during physical therapy at the Department of Physical Therapy and Rehabilitation of a regional hospital, between Jan. 2006 and Aug. 2009. The probable causes were failure on the part of the therapist to inform the patient on operation procedures and …
Health And Wellness Using Occupations To Explore Internal Motivators For Change, Shayal Ram, Susan Macdermott, Becki Cohill, Karen Park
Health And Wellness Using Occupations To Explore Internal Motivators For Change, Shayal Ram, Susan Macdermott, Becki Cohill, Karen Park
Fall 2020 Virtual OTD Capstone Symposium
The purpose of this capstone project was to create an occupation-based program that could be integrated into the lifestyle patterns of adults to potentially assist reducing the risk of Alzheimer’s disease (AD). The number of Americans living with AD is expected to grow up to 16 million by 2050 (Smallfield & Heckenlaible, 2017). The risk for developing the disease could be reduced through lifestyle modifications (Hussenoeder & Riedel-Heller, 2018). Using occupation as a means for health promotion and disease prevention is an emerging area for occupational therapy practice (AOTA, 2014). This capstone sought to increase awareness of internal motivators that …
Effect Of Duration And Amplitude Of Direct Current When Lidocaine Is Delivered By Iontophoresis, Susan A. Saliba, Courtney L. Teeter-Heyl, Patrick O. Mckeon, Christopher D. Ingeroll, Ethan N. Saliba
Effect Of Duration And Amplitude Of Direct Current When Lidocaine Is Delivered By Iontophoresis, Susan A. Saliba, Courtney L. Teeter-Heyl, Patrick O. Mckeon, Christopher D. Ingeroll, Ethan N. Saliba
Physical Therapy Faculty Publications
Dosage for the galvanic stimulation for iontophoresis varies. Clinicians manipulate the duration or the amplitude of the current, but it is not known which is more effective. We compared the anesthetic effect of lidocaine HCL (2%) by manipulating the current parameters on 21 healthy volunteers (age: 21.2 ± 4.2, height 170.7 ± 10.2 cm, mass 82.1 ± 19.2 kg). Three conditions were administered in a random order using a Phoresor II® with 2 mL, 2% lidocaine HCL in an iontophoresis electrode. (1) HASD (40 mA*min): High amplitude (4 mA), short duration (10 min); (2) LALD (40 mA.min): …
The Overtraining Syndrome In Endurance Athletes; A Guide For Coaches And Athletic Trainers For Prevention And Treatment, Shannon M. Hughes
The Overtraining Syndrome In Endurance Athletes; A Guide For Coaches And Athletic Trainers For Prevention And Treatment, Shannon M. Hughes
Graduate Theses
Training may be the most vital aspect of competition for serious athletes. The goal of training is to improve athletic performance by improving physiological performance, but there are instances when training can push an athlete physiologically beyond the threshold of tolerance. Most coaches and athletic trainers are aware that overtraining leads to physical injury when little recovery time is allowed, but what is still unclear is how overtraining affects the emotional and psychological stability of the athlete. The purpose of this guide is to educate coaches, athletic trainers, and even athletes, on the methods to potentially avoid overtraining, to recognize …
Chhs December 2011 E-Newsletter, Dr. John Bonaguro, Dean, Vashon S. Wells, Editor, Wku College Of Health And Human Services, Western Kentucky University
Chhs December 2011 E-Newsletter, Dr. John Bonaguro, Dean, Vashon S. Wells, Editor, Wku College Of Health And Human Services, Western Kentucky University
College of Health & Human Services Publications
No abstract provided.
An Examination Of The Effectiveness Of An 8-Week Bikram Yoga Program On Mindfulness, Perceived Stress, And Physical Fitness, Zoe L. Hewett, Lynda B. Ransdell, Yong Gao, Linda M. Petlichkoff, Shelley M. Lucas
An Examination Of The Effectiveness Of An 8-Week Bikram Yoga Program On Mindfulness, Perceived Stress, And Physical Fitness, Zoe L. Hewett, Lynda B. Ransdell, Yong Gao, Linda M. Petlichkoff, Shelley M. Lucas
Kinesiology Faculty Publications and Presentations
Previous research reports positive effects of yoga on health. The physical and psychological outcomes of participation in Bikram yoga are under-researched despite its increasing popularity, and this type of yoga may be significant with regards to stress management due to its unique method of practice. This study was designed to assess changes in levels of mindfulness, perceived stress, and physical fitness after participation in an 8-week Bikram yoga program. Fifty-one participants aged 20–54 years (mean, 31.57 years) were recruited by word of mouth from a large university located in the Northwestern United States. Participants attended a minimum of 20 Bikram …
Comparison Of Hip And Knee Strength And Neuromuscular Activity In Subjects With And Without Patellofemoral Pain Syndrome, Lori Ann Bolgla, Terry R. Malone, Brian R. Umberger, Timothy L. Uhl
Comparison Of Hip And Knee Strength And Neuromuscular Activity In Subjects With And Without Patellofemoral Pain Syndrome, Lori Ann Bolgla, Terry R. Malone, Brian R. Umberger, Timothy L. Uhl
Physical Therapy Faculty Publications
Purpose/Background: Historically, patellofemoral pain syndrome (PFPS) has been viewed exclusively as a knee problem. Recent findings have suggested an association between hip muscle weakness and PFPS. Altered neuromuscular activity about the hip also may contribute to PFPS; however, more limited data exist regarding this aspect. Most prior investigations also have not concurrently examined hip and knee strength and neuromuscular activity in this patient population. Additional knowledge regarding the interaction between hip and knee muscle function may enhance the current understanding of PFPS. The purpose of this study was to compare hip and knee strength and electromyographic (EMG) …
Widespread Regulation Of Mirna Biogenesis At The Dicer Step By The Cold-Inducible Rna-Binding Protein, Rbm3, Julie Pilotte, Esther E. Dupont-Versteegden, Peter W. Vanderklish
Widespread Regulation Of Mirna Biogenesis At The Dicer Step By The Cold-Inducible Rna-Binding Protein, Rbm3, Julie Pilotte, Esther E. Dupont-Versteegden, Peter W. Vanderklish
Physical Therapy Faculty Publications
MicroRNAs (miRNAs) play critical roles in diverse cellular events through their effects on translation. Emerging data suggest that modulation of miRNA biogenesis at post-transcriptional steps by RNA-binding proteins is a key point of regulatory control over the expression of some miRNAs and the cellular processes they influence. However, the extent and conditions under which the miRNA pathway is amenable to regulation at posttranscriptional steps are poorly understood. Here we show that RBM3, a cold-inducible, developmentally regulated RNA-binding protein and putative protooncogene, is an essential regulator of miRNA biogenesis. Utilizing miRNA array, Northern blot, and PCR methods, we observed that over …
Delayed Onset Muscle Soreness In People With Diabetes; Biomarkers And Nutritional Supplementation, Hani H. Al-Nakhli
Delayed Onset Muscle Soreness In People With Diabetes; Biomarkers And Nutritional Supplementation, Hani H. Al-Nakhli
Loma Linda University Electronic Theses, Dissertations & Projects
Exercise is important for controlling hemoglobin A1c, and maintaining proper glycemic control in people with diabetes. Exercise also increases the diabetics overall insulin sensitivity, and decreases their dependency on diabetes medication. However, people with diabetes are faced with metabolic and endothelial impairment, which could result in a prolonged sensation of muscle soreness following exercise. This would make it difficult for these people to sustain exercise regimes. Delayed-onset muscle soreness (DOMS) is a common problem in healthy individuals and in people who have diabetes. DOMS is a painful sensation experienced by individuals who have been recently inactive and then over-exercise. Yet, …
Comprehensive Strength Training Program For A Recreational Senior Golfer 11-Months After A Rotator Cuff Repair, Jason Brumitt, Erik P. Meira, Hui En Gilpin, Meredith Brunette
Comprehensive Strength Training Program For A Recreational Senior Golfer 11-Months After A Rotator Cuff Repair, Jason Brumitt, Erik P. Meira, Hui En Gilpin, Meredith Brunette
Faculty Publications - College of Physical Therapy
Background and Purpose: Golf is a popular sport played by hundreds of thousands of individuals of all ages and of varying skill levels. An orthopedic or sports-related injury and/or surgery may limit an individual’s sport participation, require him/her to complete a course of rehabilitation, and initiate (or resume) a sportspecific training program. Unlike the availability of evidence to guide postsurgical rehabilitation and sportspecific training of athletes from sports other than golf, there have only been two reports describing outcomes after surgery and for golfers. The purpose of this case report is to present a post-rehabilitation return to sporttraining program for …
Whole Body Vibration In Anterior Cruciate Ligament Rehabilitation, Sara Ruby Vargas
Whole Body Vibration In Anterior Cruciate Ligament Rehabilitation, Sara Ruby Vargas
All Graduate Plan B and other Reports, Spring 1920 to Spring 2023
There has been an increasing prevalence of anterior cruciate ligament (ACL) injuries. In the literature describing ACL rehabilitation program flexibility, muscle strength, proprioception, and postural stability have been identified as reoccurring struggles that have arisen during rehabilitation. Whole Body Vibration (WBV) has been investigate as a rehabilitation tool that can be used when recovering from an ACL injury. Research has suggested that WBV can be used to increase flexibility, improve muscular strength, increase proprioception, and improve postural stability. The purpose of this review is to gather the WBV protocols used in previous research and apply them to ACL rehabilitation. An …
Gender Equity And Differences In Support In The Vocational Rehabilitation System, Jennifer Faye Featherston
Gender Equity And Differences In Support In The Vocational Rehabilitation System, Jennifer Faye Featherston
Graduate Theses and Dissertations
Women with disabilities have different vocational rehabilitation (VR) experiences than men with disabilities. When they enter the VR system, they tend to be older, divorced, primary caregivers, more dependent on public assistance, and have less education and less work experience than their male counterparts. Given these differences, women may need to receive different treatment than men, yet the Civil Rights Act of 1964 (Pub.L. 88-352, 78 Stat. 241, July 2, 1964) and the Equal Protection clause of the Fourteenth Amendment state that men and women must be treated equally within the state-federal vocational rehabilitation system. Because they have been out …
Determining The Validity Of The Nintendo Wii Balance Board As An Assessment Tool For Balance, Sabrina Mae Deans
Determining The Validity Of The Nintendo Wii Balance Board As An Assessment Tool For Balance, Sabrina Mae Deans
UNLV Theses, Dissertations, Professional Papers, and Capstones
Context. Application of the Nintendo Wii-fit balance board and its games have been used in Physical Therapy clinics, showing success in individuals with neurological disorders, and has been recommended as a minimum baseline assessment of a symptoms checklist and standardized cognitive and balance assessments for concussion management by the NCAA. However, it still faces challenges of being considered a reliable and consistent tool for producing normative data in the allied healthcare. Because there is little to no evidence for the Wii-fit balance board as a valid balance assessment tool for clinical and/or research usage, the significance of this study is …
Effects Of Neck Muscle Fatigue On The Vestibulo-Ocular Reflex, Amer Al Saif
Effects Of Neck Muscle Fatigue On The Vestibulo-Ocular Reflex, Amer Al Saif
Loma Linda University Electronic Theses, Dissertations & Projects
In order to maintain balance, the brain receives and processes input from multiple sensory systems including the visual, vestibular, and somatosensory systems. The information from these systems is sent to the brain where the information is then combined, organized and interpreted. This results in the output of reflexes (vestibulo-ocular reflex [VOR] and vestibulospinal reflex [VSR]). The VOR and the VSR work together with other motor systems to control gaze stability and control whole body equilibrium. Impairment in any of these sensory systems can result in dizziness, loss of balance, and visual instability. While the contributions of the visual, vestibular, and …
Clinical Care Plan: Interdisciplinary Course (Ccpic), Marcia Levinson, Pt, Phd, Mft, Amy M Egras, Pharm.D, Bcps, E. Adel Herge, Otd, Otr/L, Kathryn Shaffer, Rn, Msn
Clinical Care Plan: Interdisciplinary Course (Ccpic), Marcia Levinson, Pt, Phd, Mft, Amy M Egras, Pharm.D, Bcps, E. Adel Herge, Otd, Otr/L, Kathryn Shaffer, Rn, Msn
Department of Physical Therapy Faculty Papers
Background/Rationale:
Interprofessional collaborative practice significantly improves patient outcomes, reduces mortality and enhances quality-of-life.
Person-focused care demands collaboration among professions in a team approach to address multiple issues including illness, prevention, and health promotion activities.
Key elements of successful implementation of interprofessional education supported by Clinical Care Plan, Interprofessional Course (CCPIC):
-Increasing knowledge of the roles, responsibilities, and competencies of multiple health professions.
-Collaborating in teams
-Recognizing the patient as the expert
-Communicating effectively
Course Statistics:
-176 students from various disciplines completed course (2008-2011).
Disciplines include:
-Medicine, Nursing, Occupational Therapy, Physical Therapy, Pharmacy
Mechanisms Of The Contextual Interference Effect In Individuals Poststroke, Nicolas Schweughofer, Jeong-Yoon Lee, Hui-Ting Goh, Youggeun Choi, Sung Shin Kim, Jill Campbell Stewart Pt,Phd, Rebecca Lewthwaite, Carolee J. Winstein
Mechanisms Of The Contextual Interference Effect In Individuals Poststroke, Nicolas Schweughofer, Jeong-Yoon Lee, Hui-Ting Goh, Youggeun Choi, Sung Shin Kim, Jill Campbell Stewart Pt,Phd, Rebecca Lewthwaite, Carolee J. Winstein
Faculty Publications
Although intermixing different motor learning tasks via random schedules enhances long-term retention compared with “blocked” schedules, the mechanism underlying this contextual interference effect has been unclear. Furthermore, previous studies have reported inconclusive results in individuals poststroke. We instructed participants to learn to produce three grip force patterns in either random or blocked schedules and measured the contextual interference effect by long-term forgetting: the change in performance between immediate and 24-h posttests. Nondisabled participants exhibited the contextual interference effect: no forgetting in the random condition but forgetting in the blocked condition. Participants at least 3 mo poststroke exhibited no forgetting in …
A Model For Enhancing Diversity, Equity, Inclusion, And Belonging In A Speech Pathology And Audiology Program, Elizabeth R Oommen R. Oommen, Peggy Goetz, Brian M. Kreisman, Megan Nickelson, Morgan Bykerk
A Model For Enhancing Diversity, Equity, Inclusion, And Belonging In A Speech Pathology And Audiology Program, Elizabeth R Oommen R. Oommen, Peggy Goetz, Brian M. Kreisman, Megan Nickelson, Morgan Bykerk
University Faculty Publications and Creative Works
Purpose: The SPAUD department at Calvin University recognized the need for initiatives that focused on intentionally enfolding and supporting Black, Indigenous, and people of color (BIPOC), international, and third culture students in a competitive major like communication sciences and disorders (CSD). These initiatives focused on diversity, equity, inclusion, and belonging (DEIB) practices, specifically: (1) to support retention and empowerment of students through peer mentoring and small group meetings; and (2) to equip the department to empower faculty and students to thrive together in the program and in their vocation through capacitybuilding.
Study design/methodology/approach: This is a case study paper outlining …
Physical Therapy News, Volume 1, Issue 1, College Of Health Professions
Physical Therapy News, Volume 1, Issue 1, College Of Health Professions
Physical Therapy News
No abstract provided.
A Systematic Review Of The Health-Related Quality Of Life Measures Following Total Knee Arthroplasty, Saurabh Mehta, Mary Law, Jean-Sebastian Roy
A Systematic Review Of The Health-Related Quality Of Life Measures Following Total Knee Arthroplasty, Saurabh Mehta, Mary Law, Jean-Sebastian Roy
Physical Therapy Faculty Research
To perform systematic review and appraisal of common patient-reported outcomes (PROs) used in measuring aspects of health-related quality of life (HRQOL) following total knee arthroplasty (TKA). Especially, the study aimed to examine whether these common PROs assess the domains of HRQOL as described in the theoretical frameworks of the HRQOL.
Motivation, Goal Orientation, Coaching, And Training Habits Of Women Ultrarunners, Rhonna Z. Krouse, Lynda Ransdell, Shelley M. Lucas, Mary Pritchard
Motivation, Goal Orientation, Coaching, And Training Habits Of Women Ultrarunners, Rhonna Z. Krouse, Lynda Ransdell, Shelley M. Lucas, Mary Pritchard
Kinesiology Faculty Publications and Presentations
Ultrarunners participate in running events that exceed the 26.2 mile marathon distance (e.g., 50 K, 50-100 miles). Very little research exists on ultrarunners, especially women. The present study is a descriptive study detailing the motivation, goal orientation, demographic characteristics (e.g., age, job demands, family structure), training habits (e.g., hours per week of training), and coach utilization of women ultrarunners. Participants (N = 344) were recruited via the Ultra Listserve and four popular ultrarunning websites, and they completed a questionnaire on motivation, goal orientation, training, and coaching using Survey Monkey. General health orientation (mean + SD) (4.71 ± 1.06) and …
Smart Rehabilitation For The 21st Century: The Tampa Smart Home For Veterans With Traumatic Brain Injury, Jan Jasiewicz, William D. Kearns, Jeffrey Craighead, James L. Fozard, Steven Scott, Jay Mccarthy
Smart Rehabilitation For The 21st Century: The Tampa Smart Home For Veterans With Traumatic Brain Injury, Jan Jasiewicz, William D. Kearns, Jeffrey Craighead, James L. Fozard, Steven Scott, Jay Mccarthy
Rehabilitation and Mental Health Counseling Faculty Publications
No abstract provided.
Peak Triceps Surae Muscle Activity Is Not Specific To Knee Flexion Angles During Mvic, Kim Hébert-Losier, Anthony G. Schneiders, José A. García, S John Sullivan, Guy G. Simoneau
Peak Triceps Surae Muscle Activity Is Not Specific To Knee Flexion Angles During Mvic, Kim Hébert-Losier, Anthony G. Schneiders, José A. García, S John Sullivan, Guy G. Simoneau
Physical Therapy Faculty Research and Publications
There is limited research on peak activity of the separate triceps surae muscles in select knee flexion (KF) positions during a maximum voluntary isometric contraction (MVIC) used to normalize EMG signals. The aim of this study was to determine how frequent peak activity occurred during an MVIC for soleus (SOL), gastrocnemius medialis (GM), and gastrocnemius lateralis (GL) in select KF positions, and if these peaks were recorded in similar KF positions. Forty-eight healthy individuals performed unilateral plantar-flexion MVIC in standing with 0°KF and 45°KF, and in sitting with 90°KF. Surface EMG of SOL, GM, and GL were collected and processed …
Bilateral Oscillatory Hip Movements Induce Windup Of Multijoint Lower Extremity Spastic Reflexes In Chronic Spinal Cord Injury, Tanya Onushko, Allison S. Hyngstrom, Brian D. Schmit
Bilateral Oscillatory Hip Movements Induce Windup Of Multijoint Lower Extremity Spastic Reflexes In Chronic Spinal Cord Injury, Tanya Onushko, Allison S. Hyngstrom, Brian D. Schmit
Physical Therapy Faculty Research and Publications
After spinal cord injury (SCI), alterations in intrinsic motoneuron properties have been shown to be partly responsible for spastic reflex behaviors in human SCI. In particular, a dysregulation of voltage-dependent depolarizing persistent inward currents (PICs) may permit sustained muscle contraction after the removal of a brief excitatory stimulus. Windup, in which the motor response increases with repeated activation, is an indicator of PICs. Although windup of homonymous stretch reflexes has been shown, multijoint muscle activity is often observed following imposed limb movements and may exhibit a similar windup phenomenon. The purpose of this study was to identify and quantify windup …
Biomechanical Effects Of Mobile Computer Location In A Vehicle Cab, Kyle Saginus, Richard W. Marklin, Patricia Seeley, Guy G. Simoneau, Stephen H. Freier
Biomechanical Effects Of Mobile Computer Location In A Vehicle Cab, Kyle Saginus, Richard W. Marklin, Patricia Seeley, Guy G. Simoneau, Stephen H. Freier
Physical Therapy Faculty Research and Publications
Objective: The objective of this research is to determine the best location to place a conventional mobile computer supported by a commercially available mount in a light truck cab.
Background: U.S. and Canadian electric utility companies are in the process of integrating mobile computers into their fleet vehicle cabs. There are no publications on the effect of mobile computer location in a vehicle cab on biomechanical loading, performance, and subjective assessment.
Method: The authors tested four locations of mobile computers in a light truck cab in a laboratory study to determine how location affected muscle activity of the lower back …
Muscle Fatigue And Motor Output Variability With Acute Stress In Healthy Young Adults And Veterans With Posttraumatic Stress Disorder, Manda Linea Keller
Muscle Fatigue And Motor Output Variability With Acute Stress In Healthy Young Adults And Veterans With Posttraumatic Stress Disorder, Manda Linea Keller
Dissertations (1934 -)
Acute stress can alter motor performance differently for men and women. The first aim of this dissertation addresses possible causes for the sex difference in the motor response of a low-intensity fatiguing contraction of the elbow flexor muscles to an acute stressor (difficult mental math) in young, healthy adults. Muscle fatigue increased for men and women when exposed to the stressor, but impairment was more prominent for the women. This work showed that fatigue in the central nervous system, specifically in cortical motor and premotor areas, as well as relaxation rates of the muscle (quantified with cortical stimulation) were not …
Use Of The Term "Elderly", Dale Avers, Marybeth Brown, Kevin Chui, Rita A. Wong, Michelle M. Lusardi
Use Of The Term "Elderly", Dale Avers, Marybeth Brown, Kevin Chui, Rita A. Wong, Michelle M. Lusardi
All PTHMS Faculty Publications
Using the term elderly for a person who is robust and independent as well as for a person who is frail and dependent says little about the individual.
Sequential Alterations In Catabolic And Anabolic Gene Expression Parallel Pathological Changes During Progression Of Monoiodoacetate-Induced Arthritis, Jin Nam, Priyangi Perera, Jie Liu, Bjoern Rath, James Deschner, Robert Gassner, Timothy A. Butterfield, Sudha Agarwal
Sequential Alterations In Catabolic And Anabolic Gene Expression Parallel Pathological Changes During Progression Of Monoiodoacetate-Induced Arthritis, Jin Nam, Priyangi Perera, Jie Liu, Bjoern Rath, James Deschner, Robert Gassner, Timothy A. Butterfield, Sudha Agarwal
Physical Therapy Faculty Publications
Chronic inflammation is one of the major causes of cartilage destruction in osteoarthritis. Here, we systematically analyzed the changes in gene expression associated with the progression of cartilage destruction in monoiodoacetate-induced arthritis (MIA) of the rat knee. Sprague Dawley female rats were given intra-articular injection of monoiodoacetate in the knee. The progression of MIA was monitored macroscopically, microscopically and by micro-computed tomography. Grade 1 damage was observed by day 5 post-monoiodoacetate injection, progressively increasing to Grade 2 by day 9, and to Grade 3-3.5 by day 21. Affymetrix GeneChip was utilized to analyze the transcriptome-wide changes in gene expression, and …