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Full-Text Articles in Rehabilitation and Therapy

Effectiveness Of An Intensive Drowning Prevention Program And Skills Retention By Children With And Without Disabilities, Anna L. Forde Otd, Otr/L, Ctrs, Emily A. Zeman Otd, Ms, Otr/L, Lynn Clarke Apr 2020

Effectiveness Of An Intensive Drowning Prevention Program And Skills Retention By Children With And Without Disabilities, Anna L. Forde Otd, Otr/L, Ctrs, Emily A. Zeman Otd, Ms, Otr/L, Lynn Clarke

International Journal of Aquatic Research and Education

This study examined the effectiveness of a drowning prevention program and the retention of swimming and water safety skills for 3-14 year-old children with and without disabilities. The intensive program, SWIM Central, used a top-down approach to teach 6 swimming and water safety skills during 10, 30-minute sessions. A post-participation parent survey results suggested that children ages 3-14 with and without disabilities who had previously participated in SWIM Central retained swimming and water safety skills to a similar degree. The current swim skill assessments showed that there was not an overall difference in swim skill performance in the presence of …


Effects Of Increased Attention Allocation On Postural Stability Related To History Of Concussion, Nicholas Reilly, Jessica Prebor, Jacquelyn Moxey, Eric Schussler Apr 2020

Effects Of Increased Attention Allocation On Postural Stability Related To History Of Concussion, Nicholas Reilly, Jessica Prebor, Jacquelyn Moxey, Eric Schussler

College of Health Sciences Posters

Postural instability is among the most common symptoms associated with concussion. However, clinical screenings for concussion are heavily reliant on self-reports of cognitive symptoms such as nausea and headache to determine if a full recovery has been achieved. The objective of this study was to determine if impairments of postural stability that are associated with the acute stages of concussion persist beyond the current clinical standards for determination of recovery from concussion. Fifty-four healthy participants were recruited for the study and divided based on whether they reported having no history of concussion (n = 27) or whether they had been …


Relationships Between Injury-Related Fear, Balance Self-Efficacy, And Dynamic Balance Performance In Those With Chronic Ankle Instability, Ashley M. B. Suttmiller, Kelly Johnson, Ryan S. Mccann Apr 2020

Relationships Between Injury-Related Fear, Balance Self-Efficacy, And Dynamic Balance Performance In Those With Chronic Ankle Instability, Ashley M. B. Suttmiller, Kelly Johnson, Ryan S. Mccann

College of Health Sciences Posters

Interactions between sensory-perceptual and motor-behavioral impairments in individuals with chronic ankle instability (CAI) are important for successful assessment and treatment of CAI. One of the most consistently reported motor-behavioral impairments is poor reach performance in a dynamic balance task. Injury-related fear is recognized as an important sensory-perceptual impairment, and those with injury-related fears may engage in protective movement strategies found to be associated with reach deficits. Injury-related fear may also impact one’s perception of ability, or self-efficacy, which has demonstrated positive associations with balance performance in other populations, but these relationships have yet to be investigated in the CAI population. …


Alexithymia Symptoms Are Not Associated With Childhood Trauma Or Crhr1 Rs110402 Genotype, Emily Wiatr, Grace Sullivan, Scott Stoltenberg Apr 2020

Alexithymia Symptoms Are Not Associated With Childhood Trauma Or Crhr1 Rs110402 Genotype, Emily Wiatr, Grace Sullivan, Scott Stoltenberg

Center for Brain, Biology, and Behavior: Faculty Publications

Alexithymia is associated with difficulties in emotional self-regulation, and alexithymia is specifically associated with an absence of emotional experience and cognition of emotion. Past research has indicated a potential association between alexithymia and the CRHR1 gene . Situational factors may also impact the expression of the CRHR1 gene within an individual. Berenbaum (1996) found associations between PTSD/childhood trauma and alexithymia. This study examined these associations using the Online Alexithymia Questionnaire-G2 (OAQ-G2) as well as DNA samples gathered from 657 participants at the University of Nebraska-Lincoln (72% women; 78.6% white; mean age= 20.34; standard deviation of 2.6). It was hypothesized that …


The Effects Of Strength And Conditioning On Functional Movement Screen™ Scores In Secondary School Basketball., Rollin Ross Dexter, Christopher P. Renggli, James May, Lindsay Larkins Mar 2020

The Effects Of Strength And Conditioning On Functional Movement Screen™ Scores In Secondary School Basketball., Rollin Ross Dexter, Christopher P. Renggli, James May, Lindsay Larkins

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Purpose: Injury prevention and mitigation are among the primary responsibilities of Athletic Trainers. Research has indicated that basketball players at the secondary-school level suffer up to 2.1 time loss injuries (TLI) per 1,000 athletic exposures (AE). It has been suggested that Functional Movement Screen (FMS™) composite and individual task scores may help determine injury risk. Researchers have suggested that a variety of strength and conditioning strategies may positively alter both composite and individual FMS™ task scores and reduce movement asymmetry. Methods: During a retrospective analysis of the records of all junior varsity and varsity basketball players at one secondary school …


Effective Treatment Of An Apparent Lateral Ankle Sprain Using A Regional Interdependent Approach With Positional Release Therapy And Mulligan Concept, Joshua K. Underwood Mar 2020

Effective Treatment Of An Apparent Lateral Ankle Sprain Using A Regional Interdependent Approach With Positional Release Therapy And Mulligan Concept, Joshua K. Underwood

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Objective: Present a pair of clinical cases demonstrating the utilization of regional interdependent (RI) evaluation and treatment in an apparent lateral ankle sprain. The utilization of both Positional Release Therapy (PRT) and Mulligan Concept (MC) on secondary school athletes with an apparent acute lateral ankle sprain are presented. Background: Lateral ankle sprains are a common injury in athletics. While the MC has been shown to be an effective manual therapy in ankle sprains, if the treatment is not pain-free it is considered not warranted. The concept of RI attempts to connect apparently unconnected dysfunctions within the body which collectively contribute …


Student Athlete Perceptions Of Athletic Trainers’ Competence Based On Appearance And Dress, Jennifer J. Rogers Mar 2020

Student Athlete Perceptions Of Athletic Trainers’ Competence Based On Appearance And Dress, Jennifer J. Rogers

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Context: Physical appearance and dress attire may be a major influence on a person’s perception of an individual’s professional competence. Objective: To examine influence of Athletic Trainer (AT) physical appearance and dress attire on student-athletes’ perception of an AT’s competence. Design: Cross-Sectional Study Setting: NATA District 5 Participants: Student athletes (n=156; female: n=71; male: n=78) from NCAA Division III and NAIA institutions participated in the study. Interventions: Participants viewed one of four Body Mass Index (BMI) specific AT images [underweight BMI=18, normal weight BMI=24, overweight BMI=30, or an obese BMI=36] while answering 36 Student Athlete Response (SAR) Form survey questions …


The Effectiveness Of An Infrapatellar Strap On Reducing Pain Associated With Patellar Tendinopathy, Jenny Toonstra, Andrea Cripps Mar 2020

The Effectiveness Of An Infrapatellar Strap On Reducing Pain Associated With Patellar Tendinopathy, Jenny Toonstra, Andrea Cripps

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Purpose: To determine the effectiveness of an infrapatellar strap on pain reduction in participants with patellar tendinopathy. Methods: Articles were identified from PubMed, CINAHL, Medline, and SportDiscus using the string “((((patellar tendinitis OR patellar tendinopathy))) AND ((cho-pat strap OR infrapatellar strap OR compression device OR brace))) AND pain” from January 2009-January 2019, resulting in nine studies. After a review of the title and abstracts, six studies were reviewed in-depth. Of these articles, four studies met the inclusion criteria. Two independent reviewers assessed the level of evidence of included studies using the Oxford Center for Evidence-Based Medicine (2009). Changes in pain …


Examining Group Differences In Emotion Regulation Strategies And The State And Trait Anxiety Of Lifeguards And Non-Lifeguards In A Real-World Precompetitive Situation, Hannah Calverley, Dr Paul Davis, Dr Jack Harvey, Dr Christopher Mesagno Feb 2020

Examining Group Differences In Emotion Regulation Strategies And The State And Trait Anxiety Of Lifeguards And Non-Lifeguards In A Real-World Precompetitive Situation, Hannah Calverley, Dr Paul Davis, Dr Jack Harvey, Dr Christopher Mesagno

International Journal of Aquatic Research and Education

The purpose of this study was to investigate differences, between swimmer-lifeguards and swimmer-non-lifeguards, in trait and state anxiety and emotion regulation techniques in a real-life precompetitive situation with a secondary focus on gender differences. The Emotion Regulation Questionnaire, Sport Anxiety Scale – 2 and the Mental Readiness Form – 3 were distributed to 100 participants at university swimming competitions in the United Kingdom. Swimmer-lifeguards displayed significantly lower cognitive (p=.03) and somatic state (p=.05) anxiety and cognitive trait anxiety (p=.02) than swimmer-non-lifeguards. Males reported significantly lower levels of cognitive and somatic trait anxiety (ppp=.01); no …


El Baloncesto Es Vida: A Look Into Strength And Conditioning, Physical Therapy, And Coaching During My Internship Abroad, Jessica Doublesin Jan 2020

El Baloncesto Es Vida: A Look Into Strength And Conditioning, Physical Therapy, And Coaching During My Internship Abroad, Jessica Doublesin

2020 Honors Symposium

An experience abroad can help a person grow in confidence and knowledge and allow them to immerse themselves in a new culture. During my time in Valencia, Spain, I was able to work at a youth basketball club, CB L’Horta Godella, alongside the club’s strength and conditioning coaches and the physical therapist and be a coach for the young athletes. The fact that I lived with a Spanish family and had an open mindset towards making friends and exploring new things allowed me to grow closer to the culture in Spain. By using my knowledge and passion for sports and …


The Impact Of Exercise In Spaceflight And Microgravity Environments, William Bybee Jan 2020

The Impact Of Exercise In Spaceflight And Microgravity Environments, William Bybee

Mahurin Honors College Capstone Experience/Thesis Projects

Since mankind’s first spaceflight, a significant barricade in reaching distant planets has been the damaging effects of microgravity upon the human body. Effects range from loss in bone mineral density and severe muscle atrophy to autoimmune disorders. The most effective countermeasure of these effects to date is exercise. Implementation of exercise in microgravity is not an easy task, so various specialized equipment must be utilized to effectively administer it. Even with this equipment, exercise as it is currently used does not entirely prevent body systems from undergoing detrimental changes. New modalities and implementations are currently being investigated that may significantly …


Neuropsychological Change After A Single Season Of Head Impact Exposure In Youth Football, Arthur C. Maerlender, Eric Smith, P. Gunnar Brolinson, Joseph J. Crisco, Jillian Urban, Amaris Ajamil, Steven Rowson, Eamon T. Campolettano, Ryan A. Gellner, Srinidhi Bellamkonda, Emily Kieffer, Mireille E. Kelley, Derek Jones, Alex Powers, Jonathan Beckwith, Joel Stitzel, Richard M. Greenwald, Stefan Duma Jan 2020

Neuropsychological Change After A Single Season Of Head Impact Exposure In Youth Football, Arthur C. Maerlender, Eric Smith, P. Gunnar Brolinson, Joseph J. Crisco, Jillian Urban, Amaris Ajamil, Steven Rowson, Eamon T. Campolettano, Ryan A. Gellner, Srinidhi Bellamkonda, Emily Kieffer, Mireille E. Kelley, Derek Jones, Alex Powers, Jonathan Beckwith, Joel Stitzel, Richard M. Greenwald, Stefan Duma

Center for Brain, Biology, and Behavior: Faculty Publications

Objectives: Head impact exposure (HIE) in youth football is a public health concern. The objective of this study was to determine if one season of HIE in youth football was related to cognitive changes.

Method: Over 200 participants (ages 9–13) wore instrumented helmets for practices and games to measure the amount of HIE sustained over one season. Pre- and post-season neuropsychological tests were completed. Test score changes were calculated adjusting for practice effects and regression to the mean and used as the dependent variables. Regression models were calculated with HIE variables predicting neuropsychological test score changes.

Results: For the full …


The Effect Of In-Service Methodology On Learning Transfer For School Personnel Managing Students Following Concussion, Jennifer Parent-Nichols, Angela Desilva Mousseau, Joshua Cleland, Jonathan D. Lichtenstein, Arthur C. Maerlender Jan 2020

The Effect Of In-Service Methodology On Learning Transfer For School Personnel Managing Students Following Concussion, Jennifer Parent-Nichols, Angela Desilva Mousseau, Joshua Cleland, Jonathan D. Lichtenstein, Arthur C. Maerlender

Center for Brain, Biology, and Behavior: Faculty Publications

Background: It is essential to increase the knowledge base of teachers involved in facilitating return to learning in middle school students following a concussion. However, the best method to enhance the transfer of learning for teachers remains to be elucidated. Application of Adult Learning Theory (ALT) is a plausible solution to this problem. Purpose: The purpose of this randomized post-test study was to examine the effects of ALTon the transfer of learning in teachers who work with individuals with concussion. Methods: A convenience sample of 169 teachers at four middle schools were randomized to receive an in-service regarding concussion management …


Sleep And Stress In The Acute Phase Of Concussion In Youth, Arthur C. Maerlender, Caitlin Masterson, Jessica L. Calvi, Todd Caze, Ross Mathiasen, Dennis Molfese Jan 2020

Sleep And Stress In The Acute Phase Of Concussion In Youth, Arthur C. Maerlender, Caitlin Masterson, Jessica L. Calvi, Todd Caze, Ross Mathiasen, Dennis Molfese

Center for Brain, Biology, and Behavior: Faculty Publications

This study sought to address the complex interplay between both biological and psychological perceptions of stress and sleep in the acute stages following a mild traumatic brain injury. A secondary goal was to identify potential targets for intervention. Eleven acutely injured youth (mean age 12 years) were studied at home with overnight actigraphy, salivary cortisol and melatonin assays, and subjective ratings of stress and fatigue (injured group). Nine matched control youth also were assessed (control group). Results suggested longer sleep latencies (time to fall asleep) and higher levels of fatigue in the injured group exist (p ¼ 0.025 and p …


The Global Assessment Of School Functioning (Gasf): Criterion Validity And Interrater Reliability, Arthur C. Maerlender, Joseph Palamara, Jonathan Lichtenstein Jan 2020

The Global Assessment Of School Functioning (Gasf): Criterion Validity And Interrater Reliability, Arthur C. Maerlender, Joseph Palamara, Jonathan Lichtenstein

Center for Brain, Biology, and Behavior: Faculty Publications

The Global Assessment of School Functioning (GASF) provides a robust estimate of a student's overall level of functioning within the school environment. It is intended to capture a global metric reflecting academic, social and general behavioral functioning within the school. It is a modification of the Global Assessment of Functioning and reflects functioning across academics, interpersonal relationships, school behavior, and school participation. It was developed to allow school personnel a means to communicate the general level of student functioning without re- verting to specific issues or immediate concerns. This paper reports on the scale's criterion validity and interrater reliability. Confirmations …


Psychometric Properties Of The Standardized Assessment Of Concussion In Youth Football: Validity, Reliability, And Demographic Factors, Arthur C. Maerlender, Eric Smith, P. Gunnar Brolinson, Jillian Urban, Steven Rowson, Amaris Ajamil, Eamon T. Campolettano, Ryan A. Gellner, Srinidhi Bellamkonda, Mireille E. Kelley, Derek Jones, Alex Powers, Jonathan Beckwith, Joseph J. Crisco, Joel Stitzel, Stefan Duma, Richard M. Greenwald Jan 2020

Psychometric Properties Of The Standardized Assessment Of Concussion In Youth Football: Validity, Reliability, And Demographic Factors, Arthur C. Maerlender, Eric Smith, P. Gunnar Brolinson, Jillian Urban, Steven Rowson, Amaris Ajamil, Eamon T. Campolettano, Ryan A. Gellner, Srinidhi Bellamkonda, Mireille E. Kelley, Derek Jones, Alex Powers, Jonathan Beckwith, Joseph J. Crisco, Joel Stitzel, Stefan Duma, Richard M. Greenwald

Center for Brain, Biology, and Behavior: Faculty Publications

The objective of this study was to determine the psychometrics (reliability, validity) of the original Standardized Assessment of Concussion (SAC) in a youth sample (ages 11 to 13). Demographic factors of race, level of vocabulary knowledge, mother’s level of education were also considered. Over 150 youth football athletes completed the SAC and a brief battery of NIH Toolbox cognitive tests as part of a larger study on biomechanical factors in youth sport concussion. This was a within-subjects design (pre-season, post-season assessments), and correlational analysis of convergent and discriminant validity. Between groups analysis based on demographic differences was also employed. The …


Modeling Interactions Between Brain Function, Diet Adherence Behaviors, And Weight Loss Success, Amanda N. Szabo-Reed, Laura E. Martin, Jinxiang Hu, Hung-Wen Yeh, Joshua Powell, Rebecca J. Lepping, Trisha M. Patrician, Florance J. Breslin, Joseph E. Donnelly, Cary R. Savage Jan 2020

Modeling Interactions Between Brain Function, Diet Adherence Behaviors, And Weight Loss Success, Amanda N. Szabo-Reed, Laura E. Martin, Jinxiang Hu, Hung-Wen Yeh, Joshua Powell, Rebecca J. Lepping, Trisha M. Patrician, Florance J. Breslin, Joseph E. Donnelly, Cary R. Savage

Center for Brain, Biology, and Behavior: Faculty Publications

Summary

Introduction: Obesity is linked to altered activation in reward and control brain cir-cuitry; however, the associated brain activity related to successful or unsuccessful weight loss (WL) is unclear.

Methods: Adults with obesity (N = 75) completed a baseline functional magnetic res-onance imaging (fMRI) scan before entering a WL intervention (ie,3-month diet and physical activity [PA] program). We conducted an exploratory analysis to identify the contributions of baseline brain activation, adherence behavior patterns, and the asso-ciated connections to WL at the conclusion of a 3-month WL intervention. Food cue-reactivity brain regions were functionally identified using fMRI to index brain activation …


Males With Chronic Ankle Instability Demonstrate Deficits In Neurocognitive Function Compared To Control And Copers, Adam B. Rosen, Melanie L. Mcgrath, Arthur C. Maerlender Jan 2020

Males With Chronic Ankle Instability Demonstrate Deficits In Neurocognitive Function Compared To Control And Copers, Adam B. Rosen, Melanie L. Mcgrath, Arthur C. Maerlender

Center for Brain, Biology, and Behavior: Faculty Publications

The purpose of this study was to determine if there were neurocognitive deficits among controls, copers and those with chronic ankle instability (CAI). Participants included those without history of ankle injury (n = 14), ankle sprain copers (n = 13) and patients with self-reported CAI (n = 14). They completed a battery of valid and reliable computer-based neurocognitive tests. The differences between neurocognitive domain scores were compared across the Control, Coper and CAI groups. Patients with CAI had lower composite memory, visual memory and simple attention compared to controls. In males with CAI, large differences in memory and attention were …


Neural Bases Of Phonological And Semantic Processing In Early Childhood, Avantika Mathur, Douglas H. Schultz, Yingying Wang Dr. Jan 2020

Neural Bases Of Phonological And Semantic Processing In Early Childhood, Avantika Mathur, Douglas H. Schultz, Yingying Wang Dr.

Center for Brain, Biology, and Behavior: Faculty Publications

During the early period of reading development, children gain phonological (letter-to-sound mapping) and semantic knowledge (storage and retrieval of word meaning). Their reading ability changes rapidly, accompanied by learning-induced brain plasticity as they learn to read. This study aims at identifying the neural bases of phonological and semantic processing in early childhood by using a combination of univariate and multivariate pattern analysis. Nineteen typically developing children between the age of five and seven performed visual word-level phonological (rhyming) and semantic (related meaning) judgment tasks during functional magnetic resonance imaging scans. Our multivariate analysis showed that young children with good reading …


Nutrition, Body Composition And Physical Activity In Malignant Pleural Disease: Associations With Patient Outcomes And Response To An Exercise Intervention, Emily Jeffery Jan 2020

Nutrition, Body Composition And Physical Activity In Malignant Pleural Disease: Associations With Patient Outcomes And Response To An Exercise Intervention, Emily Jeffery

Theses: Doctorates and Masters

Background: Patients with malignant pleural disease (MPD) have advanced cancer and high symptom burden. Goals of patient care are to optimise health-related quality-of-life (HR-QoL) and participation in daily physical activities. Supportive care interventions such as nutrition and exercise could offer benefit to patients. However, there is a lack of information on the prevalence of low muscle mass (i.e., pre-sarcopenia), malnutrition, inactivity and poor physical functioning in patients with MPD. Additionally, little is known about the factors associated with development of pre-sarcopenia and malnutrition or their associations with patient outcomes.

Purpose: The objectives were to: 1) characterise physical activity levels and …


Effects Of A Strength Training Intervention And Quality Of Life: Case Study On A Sedentary Adult Female, Lucas Frazier Jan 2020

Effects Of A Strength Training Intervention And Quality Of Life: Case Study On A Sedentary Adult Female, Lucas Frazier

Williams Honors College, Honors Research Projects

The purpose of the project is to evaluate physiological and quality of life changes in a

sedentary, senior-aged (55 or older) female using a six-week strength training

intervention. This case study will instruct how to perform a push-pull-legs split

routine by going to the gym three times per week. Prior to the six week intervention,

both quantitative and qualitative variables will be collected to assess baseline data,

including the subject’s resting heart rate, resting blood pressure, grip strength, one-

repetition maximum on seven whole body exercises (dumbbell bicep curl, tricep

pushdown, barbell bench press, wide-grip lat pull-down, seated dumbbell press, …


Biomarkers Of Inflammation In Heart Failure Patients With Reduced And Preserved Ejection Fractions: Multi-Ethnic Study Of Atherosclerosis, Michelle Lynne Stone Jan 2020

Biomarkers Of Inflammation In Heart Failure Patients With Reduced And Preserved Ejection Fractions: Multi-Ethnic Study Of Atherosclerosis, Michelle Lynne Stone

UNF Graduate Theses and Dissertations

Purpose Examine the relationships between high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6), and soluble tumor necrosis factor-α receptor-1 (sTNF-R1) and the cumulative risk of heart failure with reduced (HFrEF) and preserved (HFpEF) ejection fractions in a diverse, population-based sample. Methods Study sample included 6,814 adult (45-84 years of age) men and women who participated in the Multi-Ethnic Study of Atherosclerosis and were free of cardiovascular disease at baseline. Cox regression was used to calculate the hazard ratios (HR) associated with elevated baseline hs-CRP (> 3-10 mg/L), IL-6 (> 75th percentile) and sTNF-R1 (> 75th percentile) and risk of overall …


The Prognostic Impact Of Circulating Tumour Dna In Melanoma Patients Treated With Systemic Therapies—Beyond Braf Mutant Detection, Gabriela Marsavela, Peter A. Johansson, Michelle R. Pereira, Ashleigh C. Mcevoy, Anna L. Reid, Cleo Robinson, Lydia Warburton, Muhammad A. Khattak, Tarek M. Meniawy, Benhur Amanuel, Michael Millward, Nicholas K. Hayward, Melanie R. Ziman, Elin S. Gray, Leslie Calapre Jan 2020

The Prognostic Impact Of Circulating Tumour Dna In Melanoma Patients Treated With Systemic Therapies—Beyond Braf Mutant Detection, Gabriela Marsavela, Peter A. Johansson, Michelle R. Pereira, Ashleigh C. Mcevoy, Anna L. Reid, Cleo Robinson, Lydia Warburton, Muhammad A. Khattak, Tarek M. Meniawy, Benhur Amanuel, Michael Millward, Nicholas K. Hayward, Melanie R. Ziman, Elin S. Gray, Leslie Calapre

Research outputs 2014 to 2021

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. In this study, we evaluated the predictive value of circulating tumour DNA (ctDNA) to inform therapeutic outcomes in metastatic melanoma patients receiving systemic therapies. We analysed 142 plasma samples from metastatic melanoma patients prior to commencement of systemic therapy: 70 were treated with BRAF/MEK inhibitors and 72 with immunotherapies. Patient-specific droplet digital polymerase chain reaction assays were designed for ctDNA detection. Plasma ctDNA was detected in 56% of patients prior to first-line anti-PD1 and/or anti-CTLA-4 treatment. The detection rate in the immunotherapy cohort was comparably lower than those with BRAF inhibitors …


Therapeutic Approaches To Recovery In West Virginia, Rachel A. Wattick Jan 2020

Therapeutic Approaches To Recovery In West Virginia, Rachel A. Wattick

Graduate Theses, Dissertations, and Problem Reports (ETD)

Substance use disorder (SUD) is a prevalent problem in the United States, with 19.7 million Americans aged 12 and older battling an SUD in 2017. Multiple factors influence the risk that someone will develop an SUD, including family history, childhood trauma, community factors, and poverty. West Virginia has the highest rate of overdose deaths in the nation, and individuals in WV are at high risk of SUD due to the aforementioned risk factors. There are a variety of treatment options available to someone with an SUD. These include outpatient or inpatient treatment, detoxification, therapeutic communities, and collegiate recovery programs. Despite …


The Effects Of A 6-Week Controlled Whole-Body Vibration Training Program In Reducing Falls Risk Among Healthy Older Adults, Fabricio Saucedo Jr. Jan 2020

The Effects Of A 6-Week Controlled Whole-Body Vibration Training Program In Reducing Falls Risk Among Healthy Older Adults, Fabricio Saucedo Jr.

Open Access Theses & Dissertations

Falling is the second leading cause of accidental or injury-related death in the aging population worldwide and a leading cause of serious injury. Whole-body vibration (WBV) training has been implemented as a way to improve functional performance among the elderly and reduce the falls risk. The purposes of this study were: 1) examine to what extent a six-week course of WBV training reduced falls risk and improved fall outcomes in response to slips, and 2) examine whether the benefits of WBV training could be retained at least 2 months after the completion of the entire training session. A total of …


Structural Remodelling Of The Lumbar Multifidus, Thoracolumbar Fascia And Lateral Abdominal Wall Perimuscular Connective Tissues: A Cross-Sectional And Comparative Ultrasound Study, Christian Larivière, Richard Preuss, Dany H. Gagnon, Hakim Mecheri, Sharon M. Henry Jan 2020

Structural Remodelling Of The Lumbar Multifidus, Thoracolumbar Fascia And Lateral Abdominal Wall Perimuscular Connective Tissues: A Cross-Sectional And Comparative Ultrasound Study, Christian Larivière, Richard Preuss, Dany H. Gagnon, Hakim Mecheri, Sharon M. Henry

Études primaires

Introduction

With low back pain (LBP), remodelling of the lumbar soft tissues involves both trunk muscles and neighbouring passive connective tissues. The aim of the present study was to compare three quantitative measures of these tissues, using ultrasound imaging (USI), among healthy controls and individuals with LBP.

Methods

USI measures from 30 healthy subjects and 34 patients with non-acute LBP were compared between groups and sexes. The measures employed were (1) lumbar multifidus echogenicity (fatty/fibrosis infiltration) at three vertebral levels; (2) posterior layer thickness of the thoracolumbar fascia, and (3) thickness of the perimuscular tissues surrounding the external oblique, internal …


Characterization Of The Effect Of Exercise Dose And Integrative Nonpharmacological Therapies In The Treatment Of Chronic Pain, Anna M. Polaski Dec 2019

Characterization Of The Effect Of Exercise Dose And Integrative Nonpharmacological Therapies In The Treatment Of Chronic Pain, Anna M. Polaski

Electronic Theses and Dissertations

Chronic pain includes debilitating conditions affecting large populations of people throughout the world. These diseases are further complicated by comorbid psychological disorders which make chronic pain conditions difficult to treat. Nonpharmacological treatment options have more recently become an important mainstay of effective therapies and are currently being used to supplement or replace traditional pharmacological treatment methods. Exercise-based therapies in particular are of interest due to their demonstrated success in reducing pain symptoms as well as improving psychological outcomes. Dose is an important factor in being able to effectively prescribe treatments in the context of specific exercise interventions and specific pain …


Diary Of A Service Dog (Dropout), Kristen An Horton, Heidi Anne Horton Pittman Dec 2019

Diary Of A Service Dog (Dropout), Kristen An Horton, Heidi Anne Horton Pittman

Zea E-Books Collection

My name is Granger. I am a Labrador Retriever. I want to be a service dog. It is not always easy. This is my story. (Human's note: The most important take away is that the public, children and adults, need to learn how to not interact with service dogs. As Granger says, “I’m cute. I’m working. Please ignore me.”)


Genetic Taster Status As A Mediator Of Neural Activity And Swallowing Mechanics In Healthy Adults, Angela M. Dietsch, Ross M. Westemeyer, William G. Pearson Jr., Douglas H. Schultz Dec 2019

Genetic Taster Status As A Mediator Of Neural Activity And Swallowing Mechanics In Healthy Adults, Angela M. Dietsch, Ross M. Westemeyer, William G. Pearson Jr., Douglas H. Schultz

Center for Brain, Biology, and Behavior: Faculty Publications

As part of a larger study examining relationships between taste properties and swallowing, we assessed the influence of genetic taster status (GTS) on measures of brain activity and swallowing physiology during taste stimulation in healthy men and women. Twenty-one participants underwent videofluoroscopic swallowing study (VFSS) and functional magnetic resonance imaging (fMRI) during trials of high-intensity taste stimuli. The precisely formulated mixtures included sour, sweet-sour, lemon, and orange taste profiles and unflavored controls. Swallowing physiology was characterized via computational analysis of swallowing mechanics plus other kinematic and temporal measures, all extracted from VFSS recordings. Whole-brain analysis of fMRI data assessed blood …


Structural And Tissue-Level Adaptations Of Lumbar Intervertebral Discs In Humans With Inducible Low Back Pain Symptoms, Christian Isaiah Weber Dec 2019

Structural And Tissue-Level Adaptations Of Lumbar Intervertebral Discs In Humans With Inducible Low Back Pain Symptoms, Christian Isaiah Weber

McKelvey School of Engineering Graduate Student Theses & Dissertations

Low back pain (LBP) is a devastating musculoskeletal ailment that impacts majority of the global population. Up to 95% of cases are considered nonspecific where the origin is unclear. Although there is a diagnosis with these cases, there lacks specificity that would help individuals with treatment and pain management. Imaging techniques such as magnetic resonance imaging (MRI) are primarily utilized in the diagnosis of LBP as it illuminates internal structures of the spine. One important structure clearly identified with MRI is the intervertebral disc (IVD) that is susceptible to injury and disease. Further, diagnostic imaging is performed lying down where …