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Full-Text Articles in Influenza Virus Vaccines
The Importance Of Public Health In College Populations: Why Vaccines Are Important, Kashish Poore
The Importance Of Public Health In College Populations: Why Vaccines Are Important, Kashish Poore
Honors Program: Senior Projects (Public)
This paper examines the importance of vaccines in college populations, where high-density living environments create unique vulnerabilities to infectious disease outbreaks. Despite vaccine mandates at most institutions, research indicates that many college students possess incomplete understanding of vaccine mechanisms and importance. The paper addresses three interconnected aspects: the biological foundations of vaccine-induced immunity, the significance of vaccination in collegiate settings, and the current state of vaccine literacy among students. Historical outbreaks on campuses, including meningitis at Princeton and mumps across several institutions, highlight the consequences of undervaccination. Social media misinformation has contributed significantly to vaccine hesitancy, particularly since COVID-19. The …
Creation Of An Influenza A Virus Neuraminidase Consensus Vaccine In An Adenoviral Vector, Leigh Jahnke
Creation Of An Influenza A Virus Neuraminidase Consensus Vaccine In An Adenoviral Vector, Leigh Jahnke
Honors Program: Senior Projects (Public)
In the last decade, the estimated annual burden of the flu includes 12,000-52,000 deaths, 140,000-710,000 hospitalizations, and 9 million – 41 million illnesses (Centers for Disease Control and Prevention: Disease burden of the flu). Influenza A virus can mutate and infect a variety of different hosts, which results in frequent antigenic changes and even pandemics. This has led to increased attention on the creation of a universal Influenza A vaccine containing broader immunogenic coverage than current vaccines. Our research involved detailing the steps of the cloning process utilizing a consensus neuraminidase antigen. We utilized the pAdEasy Adenoviral Vector …