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Articles 91 - 120 of 915
Full-Text Articles in Epidemiology
Physical Exercise-Related Manifestations Of Long Covid: A Systematic Review And Meta-Analysis, Chen Zheng, Jun-Jie Chen, Zi-Han Dai, Ke-Wen Wan, Feng-Hua Sun, Jun-Hao Huang, Xiang-Ke Chen
Physical Exercise-Related Manifestations Of Long Covid: A Systematic Review And Meta-Analysis, Chen Zheng, Jun-Jie Chen, Zi-Han Dai, Ke-Wen Wan, Feng-Hua Sun, Jun-Hao Huang, Xiang-Ke Chen
Faculty, Staff and Student Publications
OBJECTIVE: This study aims to systematically assess physical exercise-related symptoms of post-acute sequelae of SARS-CoV-2 infection (PASC or long COVID) in coronavirus disease 2019 (COVID-19) survivors.
METHODS: Eight databases were systematically searched on March 03, 2024. Original studies that compared physical exercise-related parameters measured by exercise testing between COVID-19 survivors who recovered from SARS-CoV-2 infection over 3 months and non-COVID-19 controls were included. A random-effects model was utilized to determine the mean differences (MDs) or standardized MDs in the meta-analysis.
RESULTS: A total of 40 studies with 6241 COVID-19 survivors were included. The 6-min walk test, maximal oxygen consumption (VO …
Il-22 Resolves Masld Via Enterocyte Stat3 Restoration Of Diet-Perturbed Intestinal Homeostasis, Peng Zhang, Junlai Liu, Allen Lee, Irene Tsaur, Masafumi Ohira, Vivian Duong, Nicholas Vo, Kosuke Watari, Hua Su, Ju Youn Kim, Li Gu, Mandy Zhu, Shabnam Shalapour, Mojgan Hosseini, Gautam Bandyopadhyay, Suling Zeng, Cristina Llorente, Haoqi Nina Zhao, Santosh Lamichhane, Siddharth Mohan, Pieter C Dorrestein, Jerrold M Olefsky, Bernd Schnabl, Pejman Soroosh, Michael Karin
Il-22 Resolves Masld Via Enterocyte Stat3 Restoration Of Diet-Perturbed Intestinal Homeostasis, Peng Zhang, Junlai Liu, Allen Lee, Irene Tsaur, Masafumi Ohira, Vivian Duong, Nicholas Vo, Kosuke Watari, Hua Su, Ju Youn Kim, Li Gu, Mandy Zhu, Shabnam Shalapour, Mojgan Hosseini, Gautam Bandyopadhyay, Suling Zeng, Cristina Llorente, Haoqi Nina Zhao, Santosh Lamichhane, Siddharth Mohan, Pieter C Dorrestein, Jerrold M Olefsky, Bernd Schnabl, Pejman Soroosh, Michael Karin
Faculty, Staff and Student Publications
The exponential rise in metabolic dysfunction-associated steatotic liver disease (MASLD) parallels the ever-increasing consumption of energy-dense diets, underscoring the need for effective MASLD-resolving drugs. MASLD pathogenesis is linked to obesity, diabetes, "gut-liver axis" alterations, and defective interleukin-22 (IL-22) signaling. Although barrier-protective IL-22 blunts diet-induced metabolic alterations, inhibits lipid intake, and reverses microbial dysbiosis, obesogenic diets rapidly suppress its production by small intestine-localized innate lymphocytes. This results in STAT3 inhibition in intestinal epithelial cells (IECs) and expansion of the absorptive enterocyte compartment. These MASLD-sustaining aberrations were reversed by administration of recombinant IL-22, which resolved hepatosteatosis, inflammation, fibrosis, and insulin resistance. Exogenous …
A Case Demonstration Of The Open Health Natural Language Processing Toolkit From The National Covid-19 Cohort Collaborative And The Researching Covid To Enhance Recovery Programs For A Natural Language Processing System For Covid-19 Or Postacute Sequelae Of Sars Cov-2 Infection: Algorithm Development And Validation, Andrew Wen, Liwei Wang, Huan He, Sunyang Fu, Sijia Liu, David A Hanauer, Daniel R Harris, Ramakanth Kavuluru, Rui Zhang, Karthik Natarajan, Nishanth P Pavinkurve, Janos Hajagos, Sritha Rajupet, Veena Lingam, Mary Saltz, Corey Elowsky, Richard A Moffitt, Farrukh M Koraishy, Matvey B Palchuk, Jordan Donovan, Lora Lingrey, Garo Stone-Derhagopian, Robert T Miller, Andrew E Williams, Peter J Leese, Paul I Kovach, Emily R Pfaff, Mikhail Zemmel, Robert D Pates, Nick Guthe, Melissa A Haendel, Christopher G Chute, Hongfang Liu, National Covid Cohort Collaborative, Recover Initiative
A Case Demonstration Of The Open Health Natural Language Processing Toolkit From The National Covid-19 Cohort Collaborative And The Researching Covid To Enhance Recovery Programs For A Natural Language Processing System For Covid-19 Or Postacute Sequelae Of Sars Cov-2 Infection: Algorithm Development And Validation, Andrew Wen, Liwei Wang, Huan He, Sunyang Fu, Sijia Liu, David A Hanauer, Daniel R Harris, Ramakanth Kavuluru, Rui Zhang, Karthik Natarajan, Nishanth P Pavinkurve, Janos Hajagos, Sritha Rajupet, Veena Lingam, Mary Saltz, Corey Elowsky, Richard A Moffitt, Farrukh M Koraishy, Matvey B Palchuk, Jordan Donovan, Lora Lingrey, Garo Stone-Derhagopian, Robert T Miller, Andrew E Williams, Peter J Leese, Paul I Kovach, Emily R Pfaff, Mikhail Zemmel, Robert D Pates, Nick Guthe, Melissa A Haendel, Christopher G Chute, Hongfang Liu, National Covid Cohort Collaborative, Recover Initiative
Faculty, Staff and Student Publications
BACKGROUND: A wealth of clinically relevant information is only obtainable within unstructured clinical narratives, leading to great interest in clinical natural language processing (NLP). While a multitude of approaches to NLP exist, current algorithm development approaches have limitations that can slow the development process. These limitations are exacerbated when the task is emergent, as is the case currently for NLP extraction of signs and symptoms of COVID-19 and postacute sequelae of SARS-CoV-2 infection (PASC).
OBJECTIVE: This study aims to highlight the current limitations of existing NLP algorithm development approaches that are exacerbated by NLP tasks surrounding emergent clinical concepts and …
Panel Stacking Is A Threat To Consensus Statement Validity, Kasper P Kepp, Preben Aavitsland, Marcel Ballin, Francois Balloux, Stefan Baral, Kevin Bardosh, Howard Bauchner, Eran Bendavid, Raj Bhopal, Daniel T Blumstein, Paolo Boffetta, Florence Bourgeois, Adam Brufsky, Peter J Collignon, Sally Cripps, Ioana A Cristea, Nigel Curtis, Benjamin Djulbegovic, Oliver Faude, Maria Elena Flacco, Gordon H Guyatt, George Hajishengallis, Lars G Hemkens, Tammy Hoffmann, Ari R Joffe, Terry P Klassen, Despina Koletsi, Dimitrios P Kontoyiannis, Ellen Kuhl, Carlo La Vecchia, Tea Lallukka, John Lambris, Michael Levitt, Spyros Makridakis, Helena C Maltezou, Lamberto Manzoli, Ana Marusic, Clio Mavragani, David Moher, Ben W Mol, Taulant Muka, Florian Naudet, Paul W Noble, Anna Nordström, Peter Nordström, Nikolaos Pandis, Stefania Papatheodorou, Chirag J Patel, Irene Petersen, Stefan Pilz, Nikolaus Plesnila, Anne-Louise Ponsonby, Manuel A Rivas, Andrea Saltelli, Manuel Schabus, Michaéla C Schippers, Holger Schünemann, Marco Solmi, Andreas Stang, Hendrik Streeck, Joachim P Sturmberg, Lehana Thabane, Brett D Thombs, Athanasios Tsakris, Simon N Wood, John P A Ioannidis
Panel Stacking Is A Threat To Consensus Statement Validity, Kasper P Kepp, Preben Aavitsland, Marcel Ballin, Francois Balloux, Stefan Baral, Kevin Bardosh, Howard Bauchner, Eran Bendavid, Raj Bhopal, Daniel T Blumstein, Paolo Boffetta, Florence Bourgeois, Adam Brufsky, Peter J Collignon, Sally Cripps, Ioana A Cristea, Nigel Curtis, Benjamin Djulbegovic, Oliver Faude, Maria Elena Flacco, Gordon H Guyatt, George Hajishengallis, Lars G Hemkens, Tammy Hoffmann, Ari R Joffe, Terry P Klassen, Despina Koletsi, Dimitrios P Kontoyiannis, Ellen Kuhl, Carlo La Vecchia, Tea Lallukka, John Lambris, Michael Levitt, Spyros Makridakis, Helena C Maltezou, Lamberto Manzoli, Ana Marusic, Clio Mavragani, David Moher, Ben W Mol, Taulant Muka, Florian Naudet, Paul W Noble, Anna Nordström, Peter Nordström, Nikolaos Pandis, Stefania Papatheodorou, Chirag J Patel, Irene Petersen, Stefan Pilz, Nikolaus Plesnila, Anne-Louise Ponsonby, Manuel A Rivas, Andrea Saltelli, Manuel Schabus, Michaéla C Schippers, Holger Schünemann, Marco Solmi, Andreas Stang, Hendrik Streeck, Joachim P Sturmberg, Lehana Thabane, Brett D Thombs, Athanasios Tsakris, Simon N Wood, John P A Ioannidis
Faculty, Staff and Student Publications
Consensus statements can be very influential in medicine and public health. Some of these statements use systematic evidence synthesis but others fail on this front. Many consensus statements use panels of experts to deduce perceived consensus through Delphi processes. We argue that stacking of panel members toward one particular position or narrative is a major threat, especially in absence of systematic evidence review. Stacking may involve financial conflicts of interest, but nonfinancial conflicts of strong advocacy can also cause major bias. Given their emerging importance, we describe here how such consensus statements may be misleading, by analyzing in depth a …
Exploration Of Positive Deviance In Prevention Of Underweight In The Under-Five: A Qualitative Study On Low-Income Urban Families, Irwan Budiono, Lukman Fauzi, Dewi Sari Rochmayani
Exploration Of Positive Deviance In Prevention Of Underweight In The Under-Five: A Qualitative Study On Low-Income Urban Families, Irwan Budiono, Lukman Fauzi, Dewi Sari Rochmayani
Kesmas
Children under the age of five (the under-five) from low-income families are more vulnerable to experience underweight. This nutritional vulnerability is evident in the preliminary study, where 35.1% of the under-five experience underweight, and 28.48% are low-income families. This study aimed to explore Positive Deviance (PD) behaviors in preventing underweight among the under-five. The study applied a qualitative approach with a case study design. Data collection took place in July-August 2022, focusing on low-income families in the Gunung Brintik area. Data were collected through two focus group discussions, seven in-depth interviews, and five key informant interviews. Coding, subtheme, and theme …
Risk Factors For Cognitive Impairment In Adult Population Of Coastal Area: A Cross-Sectional Study In Maringkik Island, Indonesia, Herpan Syafii Harahap, Arina Windri Rivarti, Nurhidayati Nurhidayati, Fitriannisa Faradina Zubaidi, Dini Suryani, Legis Ocktaviana Saputri, Yanna Indrayana, Athalita Andhera, Muhammad Hilam, Abiyyu Didar Haq
Risk Factors For Cognitive Impairment In Adult Population Of Coastal Area: A Cross-Sectional Study In Maringkik Island, Indonesia, Herpan Syafii Harahap, Arina Windri Rivarti, Nurhidayati Nurhidayati, Fitriannisa Faradina Zubaidi, Dini Suryani, Legis Ocktaviana Saputri, Yanna Indrayana, Athalita Andhera, Muhammad Hilam, Abiyyu Didar Haq
Kesmas
Cognitive impairment is a medical condition commonly found in elderly populations, which can be due to vascular risk factors in patients. There remains limited data on risk factors for cognitive impairment among coastal region populations. This study aimed to investigate risk factors for cognitive impairment in the adult population of Maringkik Island, West Nusa Tenggara Province, Indonesia. Data collected were age, sex, education level, hypertension, antihypertensive treatment, diabetes mellitus, cigarette smoking, and body mass index status. A total of 114 participants were recruited using a consecutive sampling method. The participants’ cognitive function assessment used the Mini-Cog instrument. The cognitive impairment …
The Development Of Environmental Dna (Edna) Sampling For Arbovirus Vector Surveillance In Southern Nevada, Katharine Brooke Major
The Development Of Environmental Dna (Edna) Sampling For Arbovirus Vector Surveillance In Southern Nevada, Katharine Brooke Major
UNLV Theses, Dissertations, Professional Papers, and Capstones
Vector-borne diseases account for 17% of all infectious diseases worldwide and are responsible for more than 700,000 deaths annually. Two-thirds of the global population are at risk of arthropod-borne RNA viruses (arboviruses), spread by mosquitoes, ticks, and sandflies, with these pathogens accounting for 37% of all emerging human diseases. Arboviruses are becoming increasingly important causes of neurological disease in the United States, presenting a significant public health problem. In the absence of available vaccines and efficacious treatment options, accurate, rapid, and cost-effective surveillance of arbovirus vectors is critical for monitoring species distribution and mitigating disease transmission risk. Currently, mosquito vector …
Cerebrovascular Reactivity Mri As A Biomarker For Cerebral Small Vessel Disease–Related Cognitive Decline: Multi-Site Validation In The Markvcid Consortium, Peiying Liu, Zixuan Lin, Kaisha Hazel, George Pottanat, Cuimei Xu, Dengrong Jiang, Jay J. Pillai, Emma Lucke, Christopher E. Bauer, Brian T. Gold, Steven M. Greenburg, Karl G. Helmer, Kay Jann, Gregory Jicha, Joel Kramer, Pauline Maillard, Rachel M. Mulavelil, Pavel Rodriguez, Claudia L. Satizabal, Kristin Schwab, Sudha Seshadri, Herpreet Singh, Ángel G. Velarde Dediós, Danny J. J. Wang, Rita R. Kalyani, Abhay Moghekar, Paul B. Rosenberg, Sevil Yasar, Marilyn Albert, Hanzhang Lu
Cerebrovascular Reactivity Mri As A Biomarker For Cerebral Small Vessel Disease–Related Cognitive Decline: Multi-Site Validation In The Markvcid Consortium, Peiying Liu, Zixuan Lin, Kaisha Hazel, George Pottanat, Cuimei Xu, Dengrong Jiang, Jay J. Pillai, Emma Lucke, Christopher E. Bauer, Brian T. Gold, Steven M. Greenburg, Karl G. Helmer, Kay Jann, Gregory Jicha, Joel Kramer, Pauline Maillard, Rachel M. Mulavelil, Pavel Rodriguez, Claudia L. Satizabal, Kristin Schwab, Sudha Seshadri, Herpreet Singh, Ángel G. Velarde Dediós, Danny J. J. Wang, Rita R. Kalyani, Abhay Moghekar, Paul B. Rosenberg, Sevil Yasar, Marilyn Albert, Hanzhang Lu
Neurology Faculty Publications
INTRODUCTION: Vascular contributions to cognitive impairment and dementia (VCID) represent a major factor in cognitive decline in older adults. The present study examined the relationship between cerebrovascular reactivity (CVR) measured by magnetic resonance imaging (MRI) and cognitive function in a multi-site study, using a predefined hypothesis.
METHODS: We conducted the study in a total of three analysis sites and 263 subjects. Each site performed an identical CVR MRI procedure using 5% carbon dioxide inhalation. A global cognitive measure of Montreal Cognitive Assessment (MoCA) and an executive function measure of item response theory (IRT) score were used as outcomes.
RESULTS: CVR …
Clinical Features And Outcomes Of Pediatric And Adult Patients Hospitalized For Coronavirus Disease 2019: A Comparison Across Age Strata, Grace X Li, Komal Gopchandani, Noah Brazer, Ashley Tippett, Chris Choi, Hui-Mien Hsiao, Miriam Oseguera, Abiodun Foresythe, Sanchita Bhattacharya, Venice Servellita, Alicia Sotomayor Gonzalez, Jennifer K Spinler, Mark D Gonzalez, Dalia Gulick, Colleen Kraft, Vyjayanti Kasinathan, Yun F Wayne Wang, Jennifer Dien Bard, Pei Ying Chen, Jessica Flores-Vazquez, Audrey R Odom John, Paul J Planet, Sridevi Devaraj, Ananth V Annapragada, Ruth Ann Luna, Charles Y Chiu, Christina A Rostad
Clinical Features And Outcomes Of Pediatric And Adult Patients Hospitalized For Coronavirus Disease 2019: A Comparison Across Age Strata, Grace X Li, Komal Gopchandani, Noah Brazer, Ashley Tippett, Chris Choi, Hui-Mien Hsiao, Miriam Oseguera, Abiodun Foresythe, Sanchita Bhattacharya, Venice Servellita, Alicia Sotomayor Gonzalez, Jennifer K Spinler, Mark D Gonzalez, Dalia Gulick, Colleen Kraft, Vyjayanti Kasinathan, Yun F Wayne Wang, Jennifer Dien Bard, Pei Ying Chen, Jessica Flores-Vazquez, Audrey R Odom John, Paul J Planet, Sridevi Devaraj, Ananth V Annapragada, Ruth Ann Luna, Charles Y Chiu, Christina A Rostad
Faculty, Staff and Students Publications
BACKGROUND: Coronavirus disease 2019 (COVID-19) continues to cause hospitalizations and severe disease in children and adults.
METHODS: This study compared the risk factors, symptoms, and outcomes of children and adults hospitalized for COVID-19 from March 2020 to May 2023 across age strata at 5 US sites participating in the Predicting Viral-Associated Inflammatory Disease Severity in Children with Laboratory Diagnostics and Artificial Intelligence consortium. Eligible patients had an upper respiratory swab that tested positive for severe acute respiratory syndrome coronavirus 2 by nucleic acid amplification. Adjusted odds ratios (aOR) of clinical outcomes were determined for children versus adults, for pediatric age …
The Role Of Sexual Network Core Groups In Disease Epidemics, Jason Janeaux
The Role Of Sexual Network Core Groups In Disease Epidemics, Jason Janeaux
LSU Doctoral Dissertations
Sexually transmitted infections (STIs) remain an economic and social burden, non-discriminately affecting sexually active individuals worldwide. The unique transmission of STIs is dependent upon host and pathogen life histories, as well as the underlying network structure of the host population. Within a population there is a group of individuals, the core group, that maintains STI presence and helps sustain ongoing transmission both within the core group and in the surrounding population. While the presence of these core groups is well documented, the criteria for inclusion into a sexual core group is not. In this dissertation, I explore common factors that …
The Protective Efficacy Of A Sars-Cov-2 Vaccine Candidate B1351v Against Several Variant Challenges In K18-Hace2 Mice, Jie Yang, Huifen Fan, Anna Yang, Wenhui Wang, Xin Wan, Fengjie Lin, Dongsheng Yang, Jie Wu, Kaiwen Wang, Wei Li, Qian Cai, Lei You, Deqin Pang, Jia Lu, Changfu Guo, Jinrong Shi, Yan Sun, Xinguo Li, Kai Duan, Shuo Shen, Shengli Meng, Jing Guo, Zejun Wang
The Protective Efficacy Of A Sars-Cov-2 Vaccine Candidate B1351v Against Several Variant Challenges In K18-Hace2 Mice, Jie Yang, Huifen Fan, Anna Yang, Wenhui Wang, Xin Wan, Fengjie Lin, Dongsheng Yang, Jie Wu, Kaiwen Wang, Wei Li, Qian Cai, Lei You, Deqin Pang, Jia Lu, Changfu Guo, Jinrong Shi, Yan Sun, Xinguo Li, Kai Duan, Shuo Shen, Shengli Meng, Jing Guo, Zejun Wang
Faculty, Staff and Student Publications
The emergence of SARS-CoV-2 variants of concern (VOCs) with increased transmissibility and partial resistance to neutralization by antibodies has been observed globally. There is an urgent need for an effective vaccine to combat these variants. Our study demonstrated that the B.1.351 variant inactivated vaccine candidate (B.1.351V) generated strong binding and neutralizing antibody responses in BALB/c mice against the B.1.351 virus and other SARS-CoV-2 variants after two doses within 28 days. Immunized K18-hACE2 mice also exhibited elevated levels of live virus-neutralizing antibodies against various SARS-CoV-2 viruses. Following infection with these viruses, K18-hACE2 mice displayed a stable body weight, a high survival …
Decentralized Clinical Trials For Medications To Reduce The Risk Of Dementia: Consensus Report And Guidance, Leanne Howard, Carla Abdelnour, Erin Abner, Ricardo F. Allegri, Hiroko H. Dodge, Serge Gauthier, Camilla M. Hoyos, Gregory Jicha, Patrick G. Kehoe, Catherine J. Mummery, Adesola Ogunniyi, Nikolaos Scarmeas, Xiaoying Chen, Jodie R. Titiner, Christopher R. Weber, Ruth Peters
Decentralized Clinical Trials For Medications To Reduce The Risk Of Dementia: Consensus Report And Guidance, Leanne Howard, Carla Abdelnour, Erin Abner, Ricardo F. Allegri, Hiroko H. Dodge, Serge Gauthier, Camilla M. Hoyos, Gregory Jicha, Patrick G. Kehoe, Catherine J. Mummery, Adesola Ogunniyi, Nikolaos Scarmeas, Xiaoying Chen, Jodie R. Titiner, Christopher R. Weber, Ruth Peters
Neurology Faculty Publications
INTRODUCTION: Recent growth in the functionality and use of technology has prompted an increased interest in the potential for remote or decentralized clinical trials in dementia. There are many potential benefits associated with decentralized medication trials, but we currently lack specific recommendations for their delivery in the dementia field.
METHODS: A modified Delphi method engaged an expert panel to develop recommendations for the conduct of decentralized medication trials in dementia prevention. A working group of researchers and clinicians with expertise in dementia trials further refined the recommendations.
RESULTS: Overall, the recommendations support the delivery of decentralized trials in dementia prevention …
Determinan Kegagalan Pengobatan Pada Pasien Tuberkulosis Sensitif Obat Dewasa Di Provinsi Jawa Tengah Tahun 2022, Elizabeth Wulandari, Sudarto Ronoatmodjo
Determinan Kegagalan Pengobatan Pada Pasien Tuberkulosis Sensitif Obat Dewasa Di Provinsi Jawa Tengah Tahun 2022, Elizabeth Wulandari, Sudarto Ronoatmodjo
Jurnal Epidemiologi Kesehatan Indonesia
Tuberkulosis (TB) adalah salah satu penyakit menular penyebab kematian tertinggi di dunia. Pada populasi pasien TB, terdapat banyak faktor yang dapat meningkatkan risiko kejadian yang tidak diharapkan dari pengobatan. Tujuan dari penelitian ini adalah untuk mengidentifikasi faktor-faktor yang berhubungan dengan kegagalan pengobatan pada pasien TB dewasa di Provinsi Jawa Tengah pada tahun 2022. Studi cross-sectional ini menganalisis data sekunder dari Sistem Informasi TB (SITB), menggunakan 14.542 sampel yang memenuhi kriteria inklusi dan eksklusi. Pasien TB berusia >15 tahun dan terdapat hasil pengobatan merupakan kriteria inklusi dalam penelitian ini. Kegagalan pengobatan merupakan variabel dependen dan variabel independennya adalah usia, jenis kelamin, …
Hubungan Antara Partisipasi Dalam Pengambilan Keputusan Kesehatan Perempuan Dengan Kehamilan Yang Tidak Diinginkan, Maria Anastasia Audrey, Sudarto Ronoatmodjo
Hubungan Antara Partisipasi Dalam Pengambilan Keputusan Kesehatan Perempuan Dengan Kehamilan Yang Tidak Diinginkan, Maria Anastasia Audrey, Sudarto Ronoatmodjo
Jurnal Epidemiologi Kesehatan Indonesia
Prevalensi Kehamilan Tidak Diinginkan (KTD) di Indonesia mencapai 10,7% pada tahun 2021. Pada wanita yang sudah menikah, keputusan kesehatan mencakup keputusan tentang kontrasepsi, yang idealnya melibatkan partisipasi perempuan bersama suaminya agar dapat dilakukan secara konsisten sehingga dapat mencegah KTD. Namun, data tahun 2017 menunjukkan proporsi pengambilan keputusan kesehatan perempuan yang dilakukan perempuan bersama suami hanya sebesar 43,7%. Penelitian ini bertujuan untuk mengetahui hubungan antara partisipasi bersama antara istri dan suami dalam pengambilan keputusan kesehatan perempuan dengan terjadinya KTD. Penelitian ini menggunakan desain studi crosssectional dengan menganalisis data Survei Demografi dan Kesehatan Indonesia tahun 2017. Kriteria inklusi sampel adalah perempuan yang …
Analisis Faktor Risiko Kejadian Malaria Di Kabupaten Batu Bara Tahun 2022, Fitri Wahyuni, Tri Yunis Miko Wahyono
Analisis Faktor Risiko Kejadian Malaria Di Kabupaten Batu Bara Tahun 2022, Fitri Wahyuni, Tri Yunis Miko Wahyono
Jurnal Epidemiologi Kesehatan Indonesia
Malaria adalah masalah kesehatan yang serius dan dapat berakibat fatal, terutama pada kelompok risiko tinggi seperti bayi, anak kecil, dan ibu hamil. Selain itu, malaria juga menyebabkan anemia dan menurunkan produktivitas tenaga kerja. Pada tahun 2010, sekitar 65% kabupaten di Indonesia merupakan daerah endemis malaria, dan sekitar 45% penduduk di daerah endemis berisiko tertular malaria. Di Kabupaten Batu Bara, kasus malaria meningkat dari tahun ke tahun. Penelitian ini bertujuan untuk mengetahui faktor-faktor risiko kejadian malaria. Penelitian ini menggunakan kasus-kontrol dan dilakukan pada Juni 2022 di Kabupaten Batu Bara dengan melibatkan responden berusia 12 tahun ke atas sebanyak 170 sampel. Indiividu …
Hubungan Riwayat Komplikasi Kehamilan Dengan Kejadian Perdarahan Pasca Salin Di Indonesia (Analisis Data Survei Demografi Dan Kesehatan Indonesia 2017), Dewiyana Dewiyana, Trisari Anggondowati
Hubungan Riwayat Komplikasi Kehamilan Dengan Kejadian Perdarahan Pasca Salin Di Indonesia (Analisis Data Survei Demografi Dan Kesehatan Indonesia 2017), Dewiyana Dewiyana, Trisari Anggondowati
Jurnal Epidemiologi Kesehatan Indonesia
Perdarahan Pasca Salin (PPS) merupakan salah satu penyebab utama kematian ibu secara global dan di Indonesia. Berdasarkan Survei Demografi dan Kesehatan Indonesia (SDKI) 2017, masalah kesehatan terbesar yang dikhawatirkan oleh para ibu yang dapat membahayakan seorang wanita ketika melahirkan adalah ibu mengalami PPS (28%). Memprediksi risiko PPS adalah bagian penting dari skrining prenatal dan penilaian pada kehamilan dan persalinan sangat bergantung pada akurasi riwayat kehamilan. Studi cross-sectional ini bertujuan mengetahui hubungan antara riwayat komplikasi kehamilan dengan perdarahan pasca salin di Indonesia menggunakan SDKI 2017. Responden adalah Wanita Usia Subur (WUS) 15-49 tahun yang melahirkan anak terakhir secara per vaginam sebelum …
Pengaruh Komplikasi Kehamilan Terhadap Kematian Neonatal Dini Di Indonesia: Analisis Data Survei Demografi Dan Kesehatan Indonesia (Sdki) 2017, Fatimah Fatimah, Asri Adisasmita Prof
Pengaruh Komplikasi Kehamilan Terhadap Kematian Neonatal Dini Di Indonesia: Analisis Data Survei Demografi Dan Kesehatan Indonesia (Sdki) 2017, Fatimah Fatimah, Asri Adisasmita Prof
Jurnal Epidemiologi Kesehatan Indonesia
Kematian neonatal dini merupakan penyumbang 2/3 dari kematian neonatal yang merupakan indikator derajat kesejahteraan dan kesehatan bangsa. Tingkat kematian bayi di Indonesia masih cukup tinggi jika dibandingkan dengan negaranegara Asia lainnya. Komplikasi selama kehamilan diduga sebagai salah satu faktor utama penyebab kematian neonatal dini. Tujuan dari penelitian ini adalah untuk menentukan sejauh mana hubungan antara komplikasi kehamilan dan kematian neonatal dini di Indonesia. Penelitian ini mengadopsi pendekatan crosssectional menggunakan set data yang digunakan berasal dari Survei Demografi Kesehatan Indonesia 2017. Variabel dependen pada studi ini adalah kematian neonatal dini dari anak terakhir yang dilahirkan responden yang berusia 15 – 49 …
Pengaruh Promosi Kesehatan Melalui Media Sosial Whatsapp Terhadap Pemahaman Ibu Tentang Menu Mpasi Bergizi Di Kabupaten Sumedang, Dini Afriani, Witri Dewi Mentari, Ziana Azahra
Pengaruh Promosi Kesehatan Melalui Media Sosial Whatsapp Terhadap Pemahaman Ibu Tentang Menu Mpasi Bergizi Di Kabupaten Sumedang, Dini Afriani, Witri Dewi Mentari, Ziana Azahra
Jurnal Epidemiologi Kesehatan Indonesia
Masyarakat menggunakan media sosial sebagai platform untuk berbagi teks, gambar, suara, dan video satu sama lain dan juga dengan pelaku bisnis. Studi ini meneliti pengetahuan ibu tentang menu makanan tambahan yang khas dan kaya nutrisi dengan menggunakan media sosial Whatsapp dan teknik video/teks dalam kelompok. Tujuannya adalah untuk mengetahui dampak dari promosi kesehatan melalui media sosial Whatsapp terhadap pemahaman para ibu mengenai menu makanan tambahan yang khas dan kaya gizi untuk bayi baru lahir. Penelitian ini menggunakan desain One Group Pre-test Post-test untuk pengujian sebelum dan sesudahnya. Dalam penelitian ini, ibu dari anak-anak berusia 6 hingga 24 bulan digunakan. Ibu …
Hubungan Komorbiditas Terhadap Kondisi Akhir Pasien Covid-19 Di Rsud Siti Fatimah Provinsi Sumatera Selatan, Dewie Suranti
Hubungan Komorbiditas Terhadap Kondisi Akhir Pasien Covid-19 Di Rsud Siti Fatimah Provinsi Sumatera Selatan, Dewie Suranti
Jurnal Epidemiologi Kesehatan Indonesia
Pada tahun 2021, Indonesia menempati peringkat pertama dengan kasus COVID-19 terbanyak di ASEAN. Angka kematian COVID-19 di Indonesia sebesar 3,4% dan peringkat ke-5 ditempati oleh Provinsi Sumatera Selatan. Penelitian terdahulu menunjukkan komorbiditas berkontribusi terhadap kematian pasien COVID-19 disertai usia dan jenis kelamin. Penelitian ini bertujuan untuk menganalisis peran usia, jenis kelamin, dan komorbiditas terhadap kondisi akhir pasien COVID-19 di RSUD Siti Fatimah. Metode penelitian menggunakan desain cohort retrospective dengan analisis cox regression pendekatan model proportional hazard. Penelitian ini menggunakan data sekunder yaitu rekam medik pasien terkonfirmasi COVID-19 di RSUD Siti Fatimah dari Januari-Desember 2021 berjumlah 928 pasien yang diambil dengan …
A Comprehensive Scoping Review Of Snoezelen Room In Occupational Therapy Best Practices, Muhammad Hidayat Sahid, Andriani Pratiwi, Mohamad Ghazali Masuri, Akehsan Dahlan
A Comprehensive Scoping Review Of Snoezelen Room In Occupational Therapy Best Practices, Muhammad Hidayat Sahid, Andriani Pratiwi, Mohamad Ghazali Masuri, Akehsan Dahlan
Jurnal Epidemiologi Kesehatan Indonesia
Penelitian ini merupakan analisis komprehensif terhadap literatur, penelitian, dan sumber daya yang terkait dengan ruang Snoezelen, dengan tujuan menyajikan gambaran mengenai manfaat, praktik terbaik, dan potensi aplikasi dari lingkungan multi-sensorik ini. Tinjauan ini mensintesis dan menganalisis secara kritis informasi yang tersedia untuk berkontribusi pada pemahaman dan implementasi ruang Snoezelen bagi individu dengan kebutuhan beragam. Pencarian sistematis basis data elektronik, termasuk PubMed, PsycINFO, dan CINAHL, bersama dengan pencarian manual pada daftar referensi, mengidentifikasi 27 artikel relevan yang memenuhi kriteria inklusi. Proses seleksi yang ketat memastikan inklusi sumber yang berkualitas tinggi dan relevan. Metode ekstraksi dan sintesis data digunakan untuk mengidentifikasi tema …
Hubungan Campak Dengan Berat Badan Kurang Pada Anak Usia 24-59 Bulan Di Indonesia (Analisis Data Survei Status Gizi Indonesia 2021), Wiandhari Esa Gautami, Mondastri Korib Sudaryo
Hubungan Campak Dengan Berat Badan Kurang Pada Anak Usia 24-59 Bulan Di Indonesia (Analisis Data Survei Status Gizi Indonesia 2021), Wiandhari Esa Gautami, Mondastri Korib Sudaryo
Jurnal Epidemiologi Kesehatan Indonesia
Berat badan kurang atau underweight merupakan masalah gizi kurang yang diukur dengan perbandingan berat badan dan umur. Berat badan kurang pada balita akan mempengaruhi pertumbuhan fisik, kemampuan kognitif, meningkatkan risiko kematian dan penularan infeksi penyakit, salah satu penyakit infeksi yang umum terjadi pada balita adalah campak. Tujuan penelitian ini adalah mengetahui hubungan infeksi campak dengan berat badan kurang pada balita usia 24-59 bulan di Indonesia, dengan mengontrol variabel kovariat diantaranya jenis kelamin, usia, pendidikan ibu BBLR, riwayat TB paru, riwayat diare, riwayat ISPA, riwayat imunisasi campak dan pola makan. Studi ini menggunakan data Survei Status Gizi Indonesia (SSGI) di 34 …
Gambaran Diagnosis Tbc Di Indonesia Tahun 2020-2022, Siti Zaenab, Sudarto Ronoatmodjo, Muharnis Putri
Gambaran Diagnosis Tbc Di Indonesia Tahun 2020-2022, Siti Zaenab, Sudarto Ronoatmodjo, Muharnis Putri
Jurnal Epidemiologi Kesehatan Indonesia
Tantangan utama dalam pemberatasan TBC di Indonesia ialah mengenai penemuan kasus TBC, diagnosis merupakan salah satu strategi utama dalam penemuan kasus TBC, diperlukan informasi mengenai gambaran ketersediaan akses universal diagnosis TBC di Indonesia tahun 2020-2022 sehingga kasus TBC tersebut dapat diobati sampai sembuh dan tercapainya eliminasi TBC di tahun 2030. Tujuan dari dilakukannya studi ini ialah untuk memberikan gambaran diagnosis TBC yang ada di Indonesia pada tahun 2020-2022, studi dilakukan menggunakan data surveilans TBC (SITB) milik Kementerian Kesehatan RI. Data yang akan dievaluasi merupakan seluruh terduga TBC yang datang ke Fasyankes dan tercatat di SITB. Hasilnya adalah pada tahun 2020 …
Hubungan Penyakit Jantung Koroner Dengan Kebugaran Jasmani Pada Jemaah Haji Di Provinsi Dki Jakarta Tahun 2023, Yanti Herawati, Mondastri Korib Sudaryo
Hubungan Penyakit Jantung Koroner Dengan Kebugaran Jasmani Pada Jemaah Haji Di Provinsi Dki Jakarta Tahun 2023, Yanti Herawati, Mondastri Korib Sudaryo
Jurnal Epidemiologi Kesehatan Indonesia
Haji adalah ibadah yang membutuhkan jasmani sehat juga bugar. Permenkes terkait tentang Istithaah Kesehatan Jemaah Haji Nomor 15 Tahun 2016 membawa konsekuensi mengedepankan pemeriksaan juga pembinaan kesehatan bagi jemaah haji sehingga mampu menyelesaikan seluruh ritual ibadahnya sesuai syariat Islam. Penelitian ini bertujuan untuk menganalisis hubungan Penyakit Jantung Koroner (PJK) terhadap kebugaran jasmani jemaah haji di Provinsi DKI Jakarta Tahun 2023. Desain studi penelitian menggunakan kohort restrospektif, dengan total sampling sebanyak 4.779 sampel serta menggunakan data sekunder dari aplikasi Siskohatkes Kementerian Kesehatan RI tahun 2023. Kriteria pemilihan sampel adalah responden yang mempunyai data pemeriksaan kesehatan tahap kedua dan hasil pengukuran kebugaran …
Determinan Kejadian Hipertensi Pada Sopir Angkot Di Terminal Depok, Khairal Ummah, Fajaria Nurcandra, Balqis Hiri Bahasoan
Determinan Kejadian Hipertensi Pada Sopir Angkot Di Terminal Depok, Khairal Ummah, Fajaria Nurcandra, Balqis Hiri Bahasoan
Jurnal Epidemiologi Kesehatan Indonesia
Hipertensi masih menjadi masalah kesehatan masyarakat dan menjadi faktor penyebab berkembangnya penyakit kardiovaskular. Indonesia memiliki prevalensi hipertensi tertinggi di kawasan Asia Tenggara hipertensi yaitu sebesar 41%. Kota Depok menjadi wilayah dengan prevalensi hipertensi tertinggi yaitu sebesar 22,7%. Oleh karena itu tujuan dilakukannya penelitian ini adalah untuk mengetahui faktor-faktor hipertensi pada sopir angkot di terminal Depok. Studi cross sectional dengan jumlah sampel 84 angkot yang diwawancara menggunakan kuesioner dan tensimeter yang dilakukan pada bulan Mei-Juni 2018. Sopir-sopir tersebut dipilih secara purposive sampling dan dilakukan analisis menggunakan uji regresi logistik. Proporsi hipertensi pada sopir angkot yaitu sebesar 64,5%. Variabel yang memiliki hubungan …
Increased Incidence Of Vestibular Disorders In Patients With Sars-Cov-2, Lawrance Lee, Evan French, Daniel H Coelho, Nauman F Manzoor, Adam B Wilcox, Adam M Lee, Alexis Graves, Alfred Anzalone, Amin Manna, Amit Saha, Amy Olex, Andrea Zhou, Andrew E Williams, Andrew Southerland, Andrew T Girvin, Anita Walden, Anjali A Sharathkumar, Benjamin Amor, Benjamin Bates, Brian Hendricks, Brijesh Patel, Caleb Alexander, Carolyn Bramante, Cavin Ward-Caviness, Charisse Madlock-Brown, Christine Suver, Christopher Chute, Christopher Dillon, Chunlei Wu, Clare Schmitt, Cliff Takemoto, Dan Housman, Davera Gabriel, David A Eichmann, Diego Mazzotti, Don Brown, Eilis Boudreau, Elaine Hill, Elizabeth Zampino, Emily Carlson Marti, Emily R Pfaff, Evan French, Farrukh M Koraishy, Federico Mariona, Fred Prior, George Sokos, Greg Martin, Harold Lehmann, Heidi Spratt, Hemalkumar Mehta, Hongfang Liu, Hythem Sidky, J W Awori Hayanga, Jami Pincavitch, Jaylyn Clark, Jeremy Richard Harper, Jessica Islam, Jin Ge, Joel Gagnier, Joel H Saltz, Joel Saltz, Johanna Loomba, John Buse, Jomol Mathew, Joni L Rutter, Julie A Mcmurry, Justin Guinney, Justin Starren, Karen Crowley, Katie Rebecca Bradwell, Kellie M Walters, Ken Wilkins, Kenneth R Gersing, Kenrick Dwain Cato, Kimberly Murray, Kristin Kostka, Lavance Northington, Lee Allan Pyles, Leonie Misquitta, Lesley Cottrell, Lili Portilla, Mariam Deacy, Mark M Bissell, Marshall Clark, Mary Emmett, Mary Morrison Saltz, Matvey B Palchuk, Melissa A Haendel, Meredith Adams, Meredith Temple-O'Connor, Michael G Kurilla, Michele Morris, Nabeel Qureshi, Nasia Safdar, Nicole Garbarini, Noha Sharafeldin, Ofer Sadan, Patricia A Francis, Penny Wung Burgoon, Peter Robinson, Philip R O Payne, Rafael Fuentes, Randeep Jawa, Rebecca Erwin-Cohen, Rena Patel, Richard A Moffitt, Richard L Zhu, Rishi Kamaleswaran, Robert Hurley, Robert T Miller, Saiju Pyarajan, Sam G Michael, Samuel Bozzette, Sandeep Mallipattu, Satyanarayana Vedula, Scott Chapman, Shawn T O'Neil, Soko Setoguchi, Stephanie S Hong, Steve Johnson, Tellen D Bennett, Tiffany Callahan, Umit Topaloglu, Usman Sheikh, Valery Gordon, Vignesh Subbian, Warren A Kibbe, Wenndy Hernandez, Will Beasley, Will Cooper, William Hillegass, Xiaohan Tanner Zhang
Increased Incidence Of Vestibular Disorders In Patients With Sars-Cov-2, Lawrance Lee, Evan French, Daniel H Coelho, Nauman F Manzoor, Adam B Wilcox, Adam M Lee, Alexis Graves, Alfred Anzalone, Amin Manna, Amit Saha, Amy Olex, Andrea Zhou, Andrew E Williams, Andrew Southerland, Andrew T Girvin, Anita Walden, Anjali A Sharathkumar, Benjamin Amor, Benjamin Bates, Brian Hendricks, Brijesh Patel, Caleb Alexander, Carolyn Bramante, Cavin Ward-Caviness, Charisse Madlock-Brown, Christine Suver, Christopher Chute, Christopher Dillon, Chunlei Wu, Clare Schmitt, Cliff Takemoto, Dan Housman, Davera Gabriel, David A Eichmann, Diego Mazzotti, Don Brown, Eilis Boudreau, Elaine Hill, Elizabeth Zampino, Emily Carlson Marti, Emily R Pfaff, Evan French, Farrukh M Koraishy, Federico Mariona, Fred Prior, George Sokos, Greg Martin, Harold Lehmann, Heidi Spratt, Hemalkumar Mehta, Hongfang Liu, Hythem Sidky, J W Awori Hayanga, Jami Pincavitch, Jaylyn Clark, Jeremy Richard Harper, Jessica Islam, Jin Ge, Joel Gagnier, Joel H Saltz, Joel Saltz, Johanna Loomba, John Buse, Jomol Mathew, Joni L Rutter, Julie A Mcmurry, Justin Guinney, Justin Starren, Karen Crowley, Katie Rebecca Bradwell, Kellie M Walters, Ken Wilkins, Kenneth R Gersing, Kenrick Dwain Cato, Kimberly Murray, Kristin Kostka, Lavance Northington, Lee Allan Pyles, Leonie Misquitta, Lesley Cottrell, Lili Portilla, Mariam Deacy, Mark M Bissell, Marshall Clark, Mary Emmett, Mary Morrison Saltz, Matvey B Palchuk, Melissa A Haendel, Meredith Adams, Meredith Temple-O'Connor, Michael G Kurilla, Michele Morris, Nabeel Qureshi, Nasia Safdar, Nicole Garbarini, Noha Sharafeldin, Ofer Sadan, Patricia A Francis, Penny Wung Burgoon, Peter Robinson, Philip R O Payne, Rafael Fuentes, Randeep Jawa, Rebecca Erwin-Cohen, Rena Patel, Richard A Moffitt, Richard L Zhu, Rishi Kamaleswaran, Robert Hurley, Robert T Miller, Saiju Pyarajan, Sam G Michael, Samuel Bozzette, Sandeep Mallipattu, Satyanarayana Vedula, Scott Chapman, Shawn T O'Neil, Soko Setoguchi, Stephanie S Hong, Steve Johnson, Tellen D Bennett, Tiffany Callahan, Umit Topaloglu, Usman Sheikh, Valery Gordon, Vignesh Subbian, Warren A Kibbe, Wenndy Hernandez, Will Beasley, Will Cooper, William Hillegass, Xiaohan Tanner Zhang
Faculty, Staff and Student Publications
OBJECTIVE: Determine the incidence of vestibular disorders in patients with SARS-CoV-2 compared to the control population.
STUDY DESIGN: Retrospective.
SETTING: Clinical data in the National COVID Cohort Collaborative database (N3C).
METHODS: Deidentified patient data from the National COVID Cohort Collaborative database (N3C) were queried based on variant peak prevalence (untyped, alpha, delta, omicron 21K, and omicron 23A) from covariants.org to retrospectively analyze the incidence of vestibular disorders in patients with SARS-CoV-2 compared to control population, consisting of patients without documented evidence of COVID infection during the same period.
RESULTS: Patients testing positive for COVID-19 were significantly more likely to have …
Advancing Objective Mobile Device Use Measurement Inchildren Ages 6–11 Through Built-In Device Sensors: A Proof-Of-Concept Study, Olivia L. Finnegan, Robert Glenn Weaver Med, Phd, Hongpeng Yang, James W. White, Srihari Nelakuditi, Zifei Zhong, Rahul Ghosal Ph.D., Yan Tong, Aliye B. Cepni, Elizabeth L. Adams, Sarah Burkart Mph, Ph.D., Michael W. Beets Med, Mph, Phd, Bridget Armstrong Ph.D.
Advancing Objective Mobile Device Use Measurement Inchildren Ages 6–11 Through Built-In Device Sensors: A Proof-Of-Concept Study, Olivia L. Finnegan, Robert Glenn Weaver Med, Phd, Hongpeng Yang, James W. White, Srihari Nelakuditi, Zifei Zhong, Rahul Ghosal Ph.D., Yan Tong, Aliye B. Cepni, Elizabeth L. Adams, Sarah Burkart Mph, Ph.D., Michael W. Beets Med, Mph, Phd, Bridget Armstrong Ph.D.
Faculty Publications
Mobile devices (e.g., tablets and smartphones) have been rapidly integrated into the lives of children and have impacted howchildren engage with digital media. The portability of these devices allows for sporadic, on-demand interaction, reducing theaccuracy of self-report estimates of mobile device use. Passive sensing applications objectively monitor time spent on a givendevice but are unable to identify who is using the device, a significant limitation in child screen time research. Behavioralbiometric authentication, using embedded mobile device sensors to continuously authenticate users, could be applied toaddress this limitation. This study examined the preliminary accuracy of machine learning models trained on iPad …
Information Feedback Delays Within Epidemic Models And Their Effect On Model Dynamics., Maria K. Bouka, Christopher Strickland Dr
Information Feedback Delays Within Epidemic Models And Their Effect On Model Dynamics., Maria K. Bouka, Christopher Strickland Dr
Biology and Medicine Through Mathematics Conference
No abstract provided.
Physical Activity In Underserved Preadolescents: Characterization Of Accumulation And Patterns, Alma I. Behar, Matthew T. Mahar, Gregory Norman, John P. Elder, Michael Pratt, Patricia Dionicio, Noe C. Crespo
Physical Activity In Underserved Preadolescents: Characterization Of Accumulation And Patterns, Alma I. Behar, Matthew T. Mahar, Gregory Norman, John P. Elder, Michael Pratt, Patricia Dionicio, Noe C. Crespo
International Journal of Physical Activity and Health
Objectives: The increasing rates of physical inactivity and sedentary behaviors among youth are a significant public health concern. The greatest disparities in physical activity (PA) are experienced by underserved (racial/ethnic minority, low-income) youth. This study aimed to characterize accelerometer-measured PA behaviors in a sample of low-income, predominantly Latino, preadolescents. Methods: Participants wore wrist worn GENEActiv accelerometers for 7 days. PA levels were classified as sedentary (< 50 mg), light (50-150 mg), moderate (> 150-500 mg), vigorous (> 500 mg), and MVPA (≥ 150 mg). Time spent in PA levels and sedentary time (ST), prevalence of meeting MVPA guidelines, and PA volume were estimated from accelerometer data. Three-way …
Evaluating The Epidemiological, Hormonal, And Psychosocial Sex-Based Differences In Sports-Related Concussion Outcomes, Samantha Kanny
Evaluating The Epidemiological, Hormonal, And Psychosocial Sex-Based Differences In Sports-Related Concussion Outcomes, Samantha Kanny
All Dissertations
Sports-related concussions (SRCs) affect approximately 3.8 million athletes in the United States per year. A multitude of risk factors including age, sex, concussion history and prior medical conditions have been observed to significantly increase sports-related concussion symptom burden. Researchers have posited many reasons to explain sex-based differences in SRC outcomes, often categorized by biological characteristics or sociocultural factors, however, females are vastly underrepresented in sports-related concussion research, making it difficult to understand the true mechanisms underlying SRC sex-based differences. The goal of this dissertation is to help fill the current gap in knowledge on sex-based differences in sports-related concussion outcomes. …
One Year Follow Up Of A Cross-Sectional Study Of Hookworm Infection And Response To Deworming In Beposo, Ghana, Taylor Clarkson
One Year Follow Up Of A Cross-Sectional Study Of Hookworm Infection And Response To Deworming In Beposo, Ghana, Taylor Clarkson
Capstone Experience: Master of Public Health
Hookworms are soil-transmitted helminths that infect over 500 million people worldwide, primarily those in low-income countries. Infection with hookworm can cause anemia, malnutrition, and stunted physical and cognitive development. Deworming campaigns have attempted to combat hookworm infections in endemic areas for decades. However, there is growing variability in the effectiveness of deworming drugs, and post-treatment reinfections are abundant. There are significant gaps in our understanding of critical host-parasite factors that mediate hookworm infection, reinfection, and response to deworming treatment in endemic communities. A five-year prospective study was undertaken to better understand drivers of hookworm infection in rural Ghana and thus …