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2024

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Articles 601 - 630 of 4171

Full-Text Articles in Public Health

To Reduce Mental Illness Stigma Among Emergency Medical Service Clinicians, Agencies Must Value Workers’ Psychological Safety And Health, Bryce Hruska, Maria L. Pacella La-Barbara, Marley S. Barduhn Nov 2024

To Reduce Mental Illness Stigma Among Emergency Medical Service Clinicians, Agencies Must Value Workers’ Psychological Safety And Health, Bryce Hruska, Maria L. Pacella La-Barbara, Marley S. Barduhn

Population Health Research Brief Series

Despite the mental health burdens on emergency medical service (EMS) personnel, most workers do not seek help due to stigma. Psychosocial safety climate (PSC) refers to how much an organization creates an environment that values, supports, and protects workers’ psychological safety and health. This data slice uses data collected in 2023 from EMS workers employed in the Northeastern U.S. Census Region to examine the association between EMS agencies’ PSC levels and mental illness stigma among EMS personnel. The results show that EMS personnel at agencies with high-risk PSC levels report 38% more mental illness stigma in the workplace compared to …


A Contemporary Review Of Robotic Resection For Hepatocellular Carcinoma, William A. Preston, Nina R. Spitofsky, Adam S. Bodzin Nov 2024

A Contemporary Review Of Robotic Resection For Hepatocellular Carcinoma, William A. Preston, Nina R. Spitofsky, Adam S. Bodzin

Department of Surgery Faculty Papers

Background: Robotic hepatectomy represents an appealing treatment modality for resectable hepatocellular carcinoma (HCC). A contemporary review of robotic hepatectomy compared to laparo- scopic/open hepatectomy is necessary. Methods: We performed a literature review to identify studies between 2018–2024 comparing robotic to laparoscopic/open hepatectomy for HCC with measurable outcomes. Results: A total of 10 studies were identified, including 943 patients undergoing robotic hepatectomy compared to 1678 patients undergoing laparoscopic/open hepatectomy. Generally, while similar short/long-term survival was noted across all resection modalities, robotic hepatectomy was associated with longer operative time, shorter length of stay, and less post-operative compli- cations. An additional 4 studies …


State Capacity And Covid-19 Responses: Comparing The Us States, Kiran Auerbach, Joshua Y. Lerner, Hannah M. Ridge Nov 2024

State Capacity And Covid-19 Responses: Comparing The Us States, Kiran Auerbach, Joshua Y. Lerner, Hannah M. Ridge

Political Science Faculty Articles and Research

This article addresses the interstate differences in outcomes from the coronavirus disease COVID-19 pandemic by focusing on state capacity. State capacity refers to states’ ability to create and implement policy. We posit that states want to limit death and destruction within their borders. COVID-19 created an instance in which states had a shared, preferred outcome but had very different levels of success. Using a novel measure of state capacity that allows for subnational comparisons – and is independent of ideological political will – we show that states with greater capacity experienced fewer excess deaths during 2020 and more successfully distributed …


Shifting Employment And Perceptions Of Household Responsibilities During Early Stages Of The Covid-19 Pandemic In Nevada, Usa, Courtney Coughenour, Lung-Chang Chien, Brian Labus, Maxim Gakh, Pashtana Usufzy Nov 2024

Shifting Employment And Perceptions Of Household Responsibilities During Early Stages Of The Covid-19 Pandemic In Nevada, Usa, Courtney Coughenour, Lung-Chang Chien, Brian Labus, Maxim Gakh, Pashtana Usufzy

School of Public Health Faculty Research

Background: Employment and household responsibility are critical health determinants. The COVID-19 pandemic altered the work and social landscapes in Nevada, USA through closures of workplaces and schools/childcare centers, changing patterns of employment, and household responsibilities. This study aimed to measure changes in employment status and perceived housework responsibilities among Nevada adults in December 2020, before widespread availability of COVID-19 vaccines in a pandemic-affected economy.

Methods: Using a cross-sectional telephone survey of 1,000 Nevada adults, this study compared respondent experiences and perceptions of employment and time spent on housework in December 2020 to pre-pandemic using multinominal logistic, proportional odds, and logistic …


Examining Ptsd Prevalence Among Underserved Populations In The Integrated Community Mental Health Setting 2019 To 2022, Siran Koroukian, Stephen Zyzanski, Kurt C. Stange Nov 2024

Examining Ptsd Prevalence Among Underserved Populations In The Integrated Community Mental Health Setting 2019 To 2022, Siran Koroukian, Stephen Zyzanski, Kurt C. Stange

Faculty Scholarship

Background: The prevalence of Post Traumatic Stress Disorder (PTSD) has been rising since the start of the COVID-19 pandemic, and affects females, sexual and gender minorities, and individuals with social risks at higher rates. Objective: This study examines if the prevalence of PTSD increased from 2019 to 2022 among patients who received care in a national network of safety-net, community-based health centers with integrated behavioral health programs that serve patients at high risk for PTSD. Methods: We analyzed electronic health record data from patients with 1 or more behavioral health visits during 2019 to 2022 using repeated cross-sectional data to …


Characteristics Of Exacerbators In The Us Bronchiectasis And Ntm Research Registry: A Cross-Sectional Study, Nicole C. Lapinel, Radmila Choate, Timothy R. Aksamit, Joseph Feliciano, Kevin L. Winthrop, Andreas Schmid, Sebastian Fucile, Mark L. Metersky Nov 2024

Characteristics Of Exacerbators In The Us Bronchiectasis And Ntm Research Registry: A Cross-Sectional Study, Nicole C. Lapinel, Radmila Choate, Timothy R. Aksamit, Joseph Feliciano, Kevin L. Winthrop, Andreas Schmid, Sebastian Fucile, Mark L. Metersky

School of Medicine Faculty Publications

BACKGROUND: Exacerbations of noncystic fibrosis bronchiectasis (bronchiectasis) are associated with reduced health-related quality of life and increased mortality, likelihood of hospitalisation and lung function decline. This study investigated patient clinical characteristics associated with exacerbation frequency. METHODS: A cross-sectional cohort study of patients ≥ 18 years with bronchiectasis enrolled in the US Bronchiectasis and Nontuberculous Mycobacteria (NTM) Research Registry (BRR) September 2008-March 2020. Patients were stratified by exacerbation frequency in their 2 years before enrolment. Patient demographics, respiratory symptoms, healthcare resource utilisation, microbiology, modified bronchiectasis severity index (mBSI) and select comorbidities were collected at enrolment. Patient characteristics associated with exacerbation frequency …


Effectiveness Of Mailed Outreach And Patient Navigation To Promote Hcc Screening Process Completion: A Multicentre Pragmatic Randomised Clinical Trial, Amit G Singal, Manasa Narasimman, Darine Daher, Sruthi Yekkaluri, Yan Liu, Minjae Lee, Vanessa Cerda, Aisha Khan, Karim Seif El Dahan, Jennifer Kramer, Purva Gopal, Caitlin Murphy, Ruben Hernaez Nov 2024

Effectiveness Of Mailed Outreach And Patient Navigation To Promote Hcc Screening Process Completion: A Multicentre Pragmatic Randomised Clinical Trial, Amit G Singal, Manasa Narasimman, Darine Daher, Sruthi Yekkaluri, Yan Liu, Minjae Lee, Vanessa Cerda, Aisha Khan, Karim Seif El Dahan, Jennifer Kramer, Purva Gopal, Caitlin Murphy, Ruben Hernaez

Faculty, Staff and Students Publications

Background: Hepatocellular carcinoma (HCC) is plagued by failures across the cancer care continuum, leading to frequent late-stage diagnoses and high mortality. We evaluated the effectiveness of mailed outreach invitations plus patient navigation to promote HCC screening process completion in patients with cirrhosis.

Methods: Between April 2018 and September 2021, we conducted a multicentre pragmatic randomised clinical trial comparing mailed outreach plus patient navigation for HCC screening (n=1436) versus usual care with visit-based screening (n=1436) among patients with cirrhosis at three US health systems. Our primary outcome was screening process completion over a 36-month period, and our secondary outcome was the …


Examining Adolescence And Agency In The Midst Of International Crisis: Pandemics, Pandemonium, And Zombie Young Adult Literature, T. Hunter Strickland Nov 2024

Examining Adolescence And Agency In The Midst Of International Crisis: Pandemics, Pandemonium, And Zombie Young Adult Literature, T. Hunter Strickland

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

The COVID-19 pandemic of 2020-22 brought an abundance of changes to secondary education as students transitioned across the country to virtual and hybrid learning contexts. Teachers flexed quickly and frequently to support the learning that students acquired in these new, digital spaces even as school, district, and state demands on teaching increased. The English/Language Arts classroom pivoted along with others as teachers sought out digital reading and writing resources for students to engage in. In the midst of a national crisis, a metaphorical monster that sought to destroy, much like Beowulf ’s dragon did, adolescent readers, despite the discourses of …


A Pilot Randomized Clinical Trial Of A Smartphone-Based Application To Support At-Home Psa Screening And Culturally Tailored Prostate Cancer Education For African American Men: A Study Protocol, Jordan Neil, Bingjing Mao, Ruosi Shao, E. Ogunsanya Motolani, Summer Frank-Pearce, Michael Businelle, Michael Cookson, Kelly Stratton, Mark Doescher, Stephanie Pharr, Valerie Moise, Brianna Fleshman, Jack Fronheiser, Kimberly Estrada, Iván Flores, David Bradley, Ashley Kendrick, Adam C. Alexander Nov 2024

A Pilot Randomized Clinical Trial Of A Smartphone-Based Application To Support At-Home Psa Screening And Culturally Tailored Prostate Cancer Education For African American Men: A Study Protocol, Jordan Neil, Bingjing Mao, Ruosi Shao, E. Ogunsanya Motolani, Summer Frank-Pearce, Michael Businelle, Michael Cookson, Kelly Stratton, Mark Doescher, Stephanie Pharr, Valerie Moise, Brianna Fleshman, Jack Fronheiser, Kimberly Estrada, Iván Flores, David Bradley, Ashley Kendrick, Adam C. Alexander

School of Public Health Faculty Publications

Background: Prostate cancer is the most diagnosed cancer in Black/African American men (AA) and the second‑leading cause of cancer-related deaths. A prostate-specific antigen (PSA) blood test is an early detection screening tool for prostate cancer, but uptake of PSA screening remains low among AA men. Greater PSA screening rates among AA men, coupled with earlier treatment, may reduce disparities in prostate cancer outcomes, including mortality. The current pilot study will test the first-of-its-kind mobile health (mHealth) app to improve prostate cancer knowledge and increase PSA screening uptake among AA men using home-based screening methods. Methods: AA men aged 55 to …


Kreig: Gaining Insight Into Epidemics Through Use Of Mathematical Modeling, Christina Edholm Nov 2024

Kreig: Gaining Insight Into Epidemics Through Use Of Mathematical Modeling, Christina Edholm

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Study Of Different Treatment Strategies In Epidemic Models Using Nonlinear Model Predictive Control, Hector Puebla, Luis A. Ricardez-Sandoval, Priti Kumar Roy Nov 2024

Study Of Different Treatment Strategies In Epidemic Models Using Nonlinear Model Predictive Control, Hector Puebla, Luis A. Ricardez-Sandoval, Priti Kumar Roy

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Network Analysis Of Progress In Mathematics Research, Anna Singley Nov 2024

Network Analysis Of Progress In Mathematics Research, Anna Singley

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Picking The Low-Hanging Fruit: The Cost-Effectiveness Of Opportunistic Diabetes Screening During Tuberculosis Contact Investigations On The Texas-Mexico Border, Robert A. Mcgowan, Henry Shelton Brown, Juan C. Lopez-Alvarenga, Blanca I. Restrepo Nov 2024

Picking The Low-Hanging Fruit: The Cost-Effectiveness Of Opportunistic Diabetes Screening During Tuberculosis Contact Investigations On The Texas-Mexico Border, Robert A. Mcgowan, Henry Shelton Brown, Juan C. Lopez-Alvarenga, Blanca I. Restrepo

School of Medicine Publications

Objective: There is a known association between type 2 diabetes (diabetes) and tuberculosis (TB), and TB clinics have become hubs for new diabetes diagnosis among active patients with TB. However, despite the potential to identify diabetes patients, resources limit diabetes screening opportunities to close TB contacts. We assessed the cost-effectiveness of adding opportunistic screening for diabetes during the routine TB contact investigations conducted at TB clinics.

Research design and methods: We used a Markov-based model to simulate the costs of diabetes screening, management and health outcomes, including the incidence of complications and death. All costs were considered from a health …


The 2024 Report Of The Lancet Countdown On Health And Climate Change: Facing Record-Breaking Threats From Delayed Action, Marina Romanello, Maria Walawender, Shih-Che Hsu, Annalyse Moskeland, Yasna Palmeiro-Silva, Daniel Scamman, Zakari Ali, Nadia Ameli, Denitsa Angelova, Sonja Ayeb-Karlsson, Sara Basart, Jessica Beagley, Paul J Beggs, Luciana Blanco-Villafuerte, Wenjia Cai, Max Callaghan, Diarmid Campbell-Lendrum, Jonathan D Chambers, Victoria Chicmana-Zapata, Lingzhi Chu, Troy J Cross, Kim R Van Daalen, Carole Dalin, Niheer Dasandi, Shouro Dasgupta, Michael Davies, Robert Dubrow, Matthew J Eckelman, James D Ford, Chris Freyberg, Olga Gasparyan, Georgiana Gordon-Strachan, Michael Grubb, Samuel H Gunther, Ian Hamilton, Yun Hang, Risto Hänninen, Stella Hartinger, Kehan He, Julian Heidecke, Jeremy J Hess, Louis Jamart, Slava Jankin, Harshavardhan Jatkar, Ollie Jay, Ilan Kelman, Harry Kennard, Gregor Kiesewetter, Patrick Kinney, Dominic Kniveton, Rostislav Kouznetsov, Pete Lampard, Jason K W Lee, Bruno Lemke, Bo Li, Yang Liu, Zhao Liu, Alba Llabrés-Brustenga, Melissa Lott, Rachel Lowe, Jaime Martinez-Urtaza, Mark Maslin, Lucy Mcallister, Celia Mcmichael, Zhifu Mi, James Milner, Kelton Minor, Jan Minx, Nahid Mohajeri, Natalie C Momen, Maziar Moradi-Lakeh, Karyn Morrisey, Simon Munzert, Kris A Murray, Nick Obradovich, Megan B O'Hare, Camile Oliveira, Tadj Oreszczyn, Matthias Otto, Fereidoon Owfi, Olivia L Pearman, Frank Pega, Andrew J Perishing, Ana-Catarina Pinho-Gomes, Jamie Ponmattam, Mahnaz Rabbaniha, Jamie Rickman, Elizabeth Robinson, Joacim Rocklöv, David Rojas-Rueda, Renee N Salas, Jan C Semenza, Jodi D Sherman, Joy Shumake-Guillemot, Pratik Singh, Henrik Sjödin, Jessica Slater, Mikhail Sofiev, Cecilia Sorensen, Marco Springmann, Zélie Stalhandske, Jennifer D Stowell, Meisam Tabatabaei, Jonathon Taylor, Daniel Tong, Cathryn Tonne, Marina Treskova, Joaquin A Trinanes, Andreas Uppstu, Fabian Wagner, Laura Warnecke, Hannah Whitcombe, Peng Xian, Carol Zavaleta-Cortijo, Chi Zhang, Ran Zhang, Shihui Zhang, Ying Zhang, Qiao Zhu, Peng Gong, Hugh Montgomery, Anthony Costello Nov 2024

The 2024 Report Of The Lancet Countdown On Health And Climate Change: Facing Record-Breaking Threats From Delayed Action, Marina Romanello, Maria Walawender, Shih-Che Hsu, Annalyse Moskeland, Yasna Palmeiro-Silva, Daniel Scamman, Zakari Ali, Nadia Ameli, Denitsa Angelova, Sonja Ayeb-Karlsson, Sara Basart, Jessica Beagley, Paul J Beggs, Luciana Blanco-Villafuerte, Wenjia Cai, Max Callaghan, Diarmid Campbell-Lendrum, Jonathan D Chambers, Victoria Chicmana-Zapata, Lingzhi Chu, Troy J Cross, Kim R Van Daalen, Carole Dalin, Niheer Dasandi, Shouro Dasgupta, Michael Davies, Robert Dubrow, Matthew J Eckelman, James D Ford, Chris Freyberg, Olga Gasparyan, Georgiana Gordon-Strachan, Michael Grubb, Samuel H Gunther, Ian Hamilton, Yun Hang, Risto Hänninen, Stella Hartinger, Kehan He, Julian Heidecke, Jeremy J Hess, Louis Jamart, Slava Jankin, Harshavardhan Jatkar, Ollie Jay, Ilan Kelman, Harry Kennard, Gregor Kiesewetter, Patrick Kinney, Dominic Kniveton, Rostislav Kouznetsov, Pete Lampard, Jason K W Lee, Bruno Lemke, Bo Li, Yang Liu, Zhao Liu, Alba Llabrés-Brustenga, Melissa Lott, Rachel Lowe, Jaime Martinez-Urtaza, Mark Maslin, Lucy Mcallister, Celia Mcmichael, Zhifu Mi, James Milner, Kelton Minor, Jan Minx, Nahid Mohajeri, Natalie C Momen, Maziar Moradi-Lakeh, Karyn Morrisey, Simon Munzert, Kris A Murray, Nick Obradovich, Megan B O'Hare, Camile Oliveira, Tadj Oreszczyn, Matthias Otto, Fereidoon Owfi, Olivia L Pearman, Frank Pega, Andrew J Perishing, Ana-Catarina Pinho-Gomes, Jamie Ponmattam, Mahnaz Rabbaniha, Jamie Rickman, Elizabeth Robinson, Joacim Rocklöv, David Rojas-Rueda, Renee N Salas, Jan C Semenza, Jodi D Sherman, Joy Shumake-Guillemot, Pratik Singh, Henrik Sjödin, Jessica Slater, Mikhail Sofiev, Cecilia Sorensen, Marco Springmann, Zélie Stalhandske, Jennifer D Stowell, Meisam Tabatabaei, Jonathon Taylor, Daniel Tong, Cathryn Tonne, Marina Treskova, Joaquin A Trinanes, Andreas Uppstu, Fabian Wagner, Laura Warnecke, Hannah Whitcombe, Peng Xian, Carol Zavaleta-Cortijo, Chi Zhang, Ran Zhang, Shihui Zhang, Ying Zhang, Qiao Zhu, Peng Gong, Hugh Montgomery, Anthony Costello

Faculty, Staff and Student Publications

Despite the initial hope inspired by the 2015 Paris Agreement, the world is now dangerously close to breaching its target of limiting global multiyear mean heating to 1·5°C. Annual mean surface temperature reached a record high of 1·45°C above the pre-industrial baseline in 2023, and new temperature highs were recorded throughout 2024. The resulting climatic extremes are increasingly claiming lives and livelihoods worldwide.


Improving Infectious Disease Predictions Through The Use Of Metapopulation Sir Modeling And Graph Convolutional Neural Networks, Petr Kisselev, Padmanabhan Seshaiyer Nov 2024

Improving Infectious Disease Predictions Through The Use Of Metapopulation Sir Modeling And Graph Convolutional Neural Networks, Petr Kisselev, Padmanabhan Seshaiyer

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


A Systematic Review Of The Long-Term Efficacy Of Physical Activity Interventions In Reducing Risk Factors For Obesity In Adults, Jude Ominyi, Andrew Clifton, Noreen Cushen-Brewster Nov 2024

A Systematic Review Of The Long-Term Efficacy Of Physical Activity Interventions In Reducing Risk Factors For Obesity In Adults, Jude Ominyi, Andrew Clifton, Noreen Cushen-Brewster

International Journal of Physical Activity and Health

Background: Regular physical activity (PA) provides numerous health advantages, including lowering mortality rates and preventing obesity. Despite well-established guidelines advising 150-300 minutes of moderate-intensity or 75-150 minutes of vigorous-intensity aerobic PA weekly, sedentary lifestyles remain prevalent, especially in industrialised nations. This systematic review examines the long-term effectiveness (12-24 months) of PA interventions aimed at reducing obesity risk among adults, with a particular focus on identifying strategies that promote sustained adherence.

Methods: A comprehensive literature search was performed using multiple databases, including Cochrane Library, PubMed, and Embase, focusing on studies published between January 2004 and January 2024. The inclusion …


Evaluation Of A Trauma-Informed Care (Tic) Training Program Across Community Health Centers In Texas: A Qualitative Study, Jihye Choi, Efrat K Gabay, Aimee Rachel, Aniela Brown, Roxana Cruz, Qiheng Yan, Paula M Cuccaro Nov 2024

Evaluation Of A Trauma-Informed Care (Tic) Training Program Across Community Health Centers In Texas: A Qualitative Study, Jihye Choi, Efrat K Gabay, Aimee Rachel, Aniela Brown, Roxana Cruz, Qiheng Yan, Paula M Cuccaro

Faculty, Staff and Student Publications

BACKGROUND: In April 2019, Texas Association of Community Health Centers launched the Trauma-Informed Care (TIC) program in community health centers across Texas. This initiative aimed to transform organizational culture for consistent delivery of TIC by providing training and coaching opportunities for Trainers and Champions in each health center. This study is an interim qualitative evaluation to gain participants' insights into their experiences of and perceptions about TIC training as part of the TIC initiative.

METHODS: We conducted semi-structured key informant interviews via Zoom with Trainers across four cohorts of participating health centers between February 2020 and April 2023. We used …


Genomic Insights For Personalised Care In Lung Cancer And Smoking Cessation: Motivating At-Risk Individuals Toward Evidence-Based Health Practices, Tony Chen, Giang Pham, Louis Fox, Nina Adler, Xiaoyu Wang, Jingning Zhang, Jinyoung Byun, Younghun Han, Gretchen R B Saunders, Dajiang Liu, Michael J Bray, Alex T Ramsey, James Mckay, Laura J Bierut, Christopher I Amos, Rayjean J Hung, Xihong Lin, Haoyu Zhang, Li-Shiun Chen Nov 2024

Genomic Insights For Personalised Care In Lung Cancer And Smoking Cessation: Motivating At-Risk Individuals Toward Evidence-Based Health Practices, Tony Chen, Giang Pham, Louis Fox, Nina Adler, Xiaoyu Wang, Jingning Zhang, Jinyoung Byun, Younghun Han, Gretchen R B Saunders, Dajiang Liu, Michael J Bray, Alex T Ramsey, James Mckay, Laura J Bierut, Christopher I Amos, Rayjean J Hung, Xihong Lin, Haoyu Zhang, Li-Shiun Chen

Faculty, Staff and Students Publications

BACKGROUND: Lung cancer and tobacco use pose significant global health challenges, necessitating a comprehensive translational roadmap for improved prevention strategies such as cancer screening and tobacco treatment, which are currently under-utilised. Polygenic risk scores (PRSs) may further motivate health behaviour change in primary care for lung cancer in diverse populations. In this work, we introduce the GREAT care paradigm, which integrates PRSs within comprehensive patient risk profiles to motivate positive health behaviour changes.

METHODS: We developed PRSs using large-scale multi-ancestry genome-wide association studies and standardised PRS distributions across all ancestries. We validated our PRSs in 561,776 individuals of diverse ancestry …


Unmeasured Confounding In Summary Estimates Of Maternal Periodontitis And Adverse Birth Outcomes: Meta-Analyses Of Observational Studies, May Salama, Abdullah Al-Taiar, Denise Mickenny Nov 2024

Unmeasured Confounding In Summary Estimates Of Maternal Periodontitis And Adverse Birth Outcomes: Meta-Analyses Of Observational Studies, May Salama, Abdullah Al-Taiar, Denise Mickenny

Graduate Student Government Association Research Conference

Abstract

Importance Maternal periodontitis has been consistently linked to adverse birth outcomes. However, a causal relationship is not established due to potential unmeasured confounding factors in observational studies and inconclusive results from randomized controlled trials.

Objective To assess the impact of unmeasured confounding factors in meta-analyses examining associations between maternal periodontal disease and preterm birth or low birth weight.

Data Sources PubMed/Medline, the Cochrane database for systematic reviews, Embase, Google Scholar, and a manual search of the reported references between 2002 and 2023.

Study Selection Systematic reviews with meta-analyses of observational studies were included if either preterm birth or low …


Investigating The Bidirectional Association Between Sociodemographic Predictors And Self-Reported Depression Among Adults In The United Arab Emirates, Mitha Abdallah Albalushi Nov 2024

Investigating The Bidirectional Association Between Sociodemographic Predictors And Self-Reported Depression Among Adults In The United Arab Emirates, Mitha Abdallah Albalushi

Thesis/ Dissertation Defenses

Background: Globally, the prevalence of depression among adults is increasing, adversely affecting public health, daily functioning, and productivity. Epidemiological studies have established a strong correlation between depression and other risk factors. However, the aspects of this relationship have not been thoroughly explored in the United Arab Emirates (UAE). The aim of this study was to explore the association between self-perceived depression and other risk factors, such as sociodemographic characteristics, sleep duration, body mass index (BMI), and underlying chronic diseases such as diabetes and hypertension after adjustment for age and gender, among Emirati Adults. Methods: This cross-sectional study is part of …


Socioecological Factors Influencing The Anticipated Medical Help-Seeking Time For Breast Cancer Among Women In Togo, A Sub-Saharan Country, Komi Blewussi Aheto Nov 2024

Socioecological Factors Influencing The Anticipated Medical Help-Seeking Time For Breast Cancer Among Women In Togo, A Sub-Saharan Country, Komi Blewussi Aheto

Walden Dissertations and Doctoral Studies

Breast cancer remains a leading cause of death in sub-Saharan Africa (SSA). The burden of the disease in the region is partly attributed to delayed health-seeking, resulting in advanced disease presentation, delayed diagnosis, poor outcomes, and low survival. This quantitative cross-sectional study was conducted to investigate the socioecological factors that influence the anticipated medical health-seeking time for women in SSA experiencing breast cancer symptoms. The socioecological model (SEM) theoretical framework guided this study. A questionnaire was used to collect data from randomly selected (N = 343) women aged 18 years and older with no personal or familial history of breast …


Commentary: Obstructive Sleep Apnea In The Hemodialysis Population: Are Clinicians Putting Existing Scientific Evidence Into Practice?, Aleena Jamal, Som Singh, Fawad Qureshi Nov 2024

Commentary: Obstructive Sleep Apnea In The Hemodialysis Population: Are Clinicians Putting Existing Scientific Evidence Into Practice?, Aleena Jamal, Som Singh, Fawad Qureshi

SKMC Student Presentations and Publications

No abstract provided.


Addressing Practice Effects In Population-Based Studies Of Trends In Late-Life Dementia And Cognitive Impairment, Vicki A Freedman, Mengyao Hu Nov 2024

Addressing Practice Effects In Population-Based Studies Of Trends In Late-Life Dementia And Cognitive Impairment, Vicki A Freedman, Mengyao Hu

Faculty, Staff and Student Publications

No abstract provided.


Estimating The Number Of Polygenic Diseases Among Six Mutually Exclusive Entities Of Non-Tumors And Cancer, C I Edvard Smith, Jan A Burger, Rula Zain Nov 2024

Estimating The Number Of Polygenic Diseases Among Six Mutually Exclusive Entities Of Non-Tumors And Cancer, C I Edvard Smith, Jan A Burger, Rula Zain

Faculty, Staff and Student Publications

In the era of precision medicine with increasing amounts of sequenced cancer and non-cancer genomes of different ancestries, we here enumerate the resulting polygenic disease entities. Based on the cell number status, we first identified six fundamental types of polygenic illnesses, five of which are non-cancerous. Like complex, non-tumor disorders, neoplasms normally carry alterations in multiple genes, including in 'Drivers' and 'Passengers'. However, tumors also lack certain genetic alterations/epigenetic changes, recently named 'Goners', which are toxic for the neoplasm and potentially constitute therapeutic targets. Drivers are considered essential for malignant transformation, whereas environmental influences vary considerably among both types of …


Evaluation Of A Primary Care Community Health Center’S Mammogram Program In Relation To Current Evidence-Based Practice., Brianna Childress Nov 2024

Evaluation Of A Primary Care Community Health Center’S Mammogram Program In Relation To Current Evidence-Based Practice., Brianna Childress

Doctoral Dissertations & Projects

Breast cancer is the second leading cause of cancer deaths among women over 50 years of age. Although mammograms have been proven to be effective in early detection of breast cancer, compliance rates are declining in the United States making it an objective for Healthy People 2030 to achieve and maintain a national compliance rate of 80.3%. For early detection of breast cancer among women between 50 to 74 years old to occur, an effective breast cancer screening program is vital. To understand why mammogram compliance rates were below the national average at a primary care community health center in …


Validation Of An Artificial Intelligence-Based Prognostic Biomarker In Patients With Oligometastatic Castration-Sensitive Prostate Cancer, Jarey H. Wang, Matthew P. Deek, Adrianna A. Mendes, Yang Song, Amol Shetty, Soha Bazyar, Kim Van Der Eecken, Emmalyn Chen, Timothy N. Showalter, Trevor J. Royce, Tamara Todorovic, Huei-Chung Huang, Scott A. Houck, Rikiya Yamashita, Ana P. Kiess, Daniel Y. Song, Tamara Lotan, Theodore Deweese, Luigi Marchionni, Lei Ren, Amit Sawant, Nicole L. Simone, Alejandro Berlin, Cem Onal, Andre Esteva, Felix Y. Feng, Phuoc T. Tran, Philip Sutera, Piet Ost Nov 2024

Validation Of An Artificial Intelligence-Based Prognostic Biomarker In Patients With Oligometastatic Castration-Sensitive Prostate Cancer, Jarey H. Wang, Matthew P. Deek, Adrianna A. Mendes, Yang Song, Amol Shetty, Soha Bazyar, Kim Van Der Eecken, Emmalyn Chen, Timothy N. Showalter, Trevor J. Royce, Tamara Todorovic, Huei-Chung Huang, Scott A. Houck, Rikiya Yamashita, Ana P. Kiess, Daniel Y. Song, Tamara Lotan, Theodore Deweese, Luigi Marchionni, Lei Ren, Amit Sawant, Nicole L. Simone, Alejandro Berlin, Cem Onal, Andre Esteva, Felix Y. Feng, Phuoc T. Tran, Philip Sutera, Piet Ost

Department of Radiation Oncology Faculty Papers

BACKGROUND: There is a need for clinically actionable prognostic and predictive tools to guide the management of oligometastatic castration-sensitive prostate cancer (omCSPC).

METHODS: This is a multicenter retrospective study to assess the prognostic and predictive performance of a multimodal artificial intelligence biomarker (MMAI; the ArteraAI Prostate Test) in men with omCSPC (n = 222). The cohort also included 51 patients from the STOMP and ORIOLE phase 2 clinical trials which randomized patients to observation versus metastasis-directed therapy (MDT). MMAI scores were computed from digitized histopathology slides and clinical variables. Overall survival (OS) and time to castration-resistant prostate cancer (TTCRPC) were …


Feature Selection And Machine Learning Approaches In Prediction Of Current E-Cigarette Use Among U.S. Adults In 2022, Wei Fang, Ying Liu, Chun Xu, Xingguang Luo, Kesheng Wang Nov 2024

Feature Selection And Machine Learning Approaches In Prediction Of Current E-Cigarette Use Among U.S. Adults In 2022, Wei Fang, Ying Liu, Chun Xu, Xingguang Luo, Kesheng Wang

Health & Biomedical Sciences Faculty Publications

Feature selection is essentially the process of picking informative and relevant features from a larger collection of features. Few studies have focused on predictors for current e-cigarette use among U.S. adults using feature selection and machine learning (ML) approaches. This study aimed to perform feature selection and develop ML approaches in prediction of current e-cigarette use using the 2022 Health Information National Trends Survey (HINTS 6). The Boruta algorithm and the least absolute shrinkage and selection operator (LASSO) were used to perform feature selection of 71 variables. The random oversampling example (ROSE) method was utilized to deal with imbalance data. …


Evaluation Of Sirtuin 1 As A Predictor Of Cardiovascular Outcomes In Diabetic Patients With Limb-Threatening Ischemia, Federico Biscetti, Maria Margherita Rando, Maria Anna Nicolazzi, Enrica Rossini, Michele Santoro, Flavia Angelini, Roberto Iezzi, Luis H. Eraso, Paul J. Dimuzio, Dario Pitocco, Massimo Massetti, Antonio Gasbarrini, Andrea Flex Nov 2024

Evaluation Of Sirtuin 1 As A Predictor Of Cardiovascular Outcomes In Diabetic Patients With Limb-Threatening Ischemia, Federico Biscetti, Maria Margherita Rando, Maria Anna Nicolazzi, Enrica Rossini, Michele Santoro, Flavia Angelini, Roberto Iezzi, Luis H. Eraso, Paul J. Dimuzio, Dario Pitocco, Massimo Massetti, Antonio Gasbarrini, Andrea Flex

Department of Surgery Faculty Papers

Chronic limb-threatening ischemia (CLTI) significantly increases the risk of major adverse limb events (MALE) and major adverse cardiac events (MACE) after lower extremity revascularization (LER). This study aims to identify novel biomarkers that help to further reduce the risk of postoperative cardiovascular complications. In this prospective, nonrandomized, observational study, baseline serum levels of sirtuin 1 (SIRT1) were assessed in 147 diabetic patients scheduled for LER due to CLTI, and participants were followed for the occurrence of MALE and MACE over 12 months. Fifty-three patients experienced MALE, and 33 experienced MACE within the follow-up period. Lower baseline SIRT1 levels were significantly …


Test Smart, Treat Smart-Using Clinician Feedback To Adapt A Catheter-Associated Urinary Tract Infection Intervention For Spinal Cord Injury, Hilary Touchett, Kelley Arredondo, Casey Hines-Munson, Ivy Poon, Sally Ann Holmes, Barbara W Trautner, Felicia Skelton Nov 2024

Test Smart, Treat Smart-Using Clinician Feedback To Adapt A Catheter-Associated Urinary Tract Infection Intervention For Spinal Cord Injury, Hilary Touchett, Kelley Arredondo, Casey Hines-Munson, Ivy Poon, Sally Ann Holmes, Barbara W Trautner, Felicia Skelton

Faculty, Staff and Students Publications

Background: Catheter-associated urinary tract infection (CAUTI) prevention is a major target for hospital quality metrics because it is linked to increased morbidity, mortality, and health care costs. Health care systems use strict protocols surrounding catheterization and maintenance, which often disregard the clinical needs of special populations (eg, spinal cord injury [SCI]). However, for populations that rely on chronic instrumentation of the bladder, asymptomatic (ie, nonpathogenic) bacterial colonization in the bladder is common but not linked to adverse outcomes. Additionally, alterations in neurologic and sensory function after SCI make it difficult for clinicians to discern asymptomatic bacteriuria from acute urinary tract …


Understanding The Impact Of Covid-19 On Yoga Instruction: Examining Teaching Methodology, Class Components, And Injury Patterns In The Northeastern Us, Sojung Kim, June Solow, Donald H Lein, Harshvardhan Singh Nov 2024

Understanding The Impact Of Covid-19 On Yoga Instruction: Examining Teaching Methodology, Class Components, And Injury Patterns In The Northeastern Us, Sojung Kim, June Solow, Donald H Lein, Harshvardhan Singh

Rowan-Virtua School of Osteopathic Medicine Departmental Research

OBJECTIVES: This study aimed to examine the impact of COVID-19 on the perspectives of yoga instructors (YIs) regarding teaching methodology, class components, and yoga-related injuries among their clients DESIGN: A cross-sectional design in this study.

SETTING: A total of 407 YIs from Northeastern United States completed a customized, web-based survey.

MAIN OUTCOME MEASURES: Chi-square tests were carried out to determine changes in yoga teaching format before and during the pandemic, as well as the counts of yoga related injuries between face-to-face (FtoF) and online teaching format. Independent t tests were used to compare the characteristics of yoga teaching elements.

RESULTS: …