Public Health Commons^™

Conflict With Peer: To Contrast Or Not To Contrast?, Malik Al-Jamal, Edward Abarado, Kendall Brothers, Laura Geneseo, Marla Adam, Nolan Tews, Sahalia Rashid

Patient Education Projects

No abstract provided.

Features Of Acute Covid-19 Associated With Post-Acute Sequelae Of Sars-Cov-2 Phenotypes: Results From The Impacc Study, Al Ozonoff, Naresh Doni Jayavelu, Shanshan Liu, Esther Melamed, Carly E Milliren, Jingjing Qi, Linda N Geng, Grace A Mccomsey, Charles B Cairns, Lindsey R Baden, Joanna Schaenman, Albert C Shaw, Hady Samaha, Vicki Seyfert-Margolis, Florian Krammer, Lindsey B Rosen, Hanno Steen, Caitlin Syphurs, Ravi Dandekar, Casey P Shannon, Rafick P Sekaly, Lauren I R Ehrlich, David B Corry, Farrah Kheradmand, Mark A Atkinson, Scott C Brakenridge, Nelson I Agudelo Higuita, Jordan P Metcalf, Catherine L Hough, William B Messer, Bali Pulendran, Kari C Nadeau, Mark M Davis, Ana Fernandez Sesma, Viviana Simon, Harm Van Bakel, Seunghee Kim-Schulze, David A Hafler, Ofer Levy, Monica Kraft, Chris Bime, Elias K Haddad, Carolyn S Calfee, David J Erle, Charles R Langelier, Walter Eckalbar, Steven E Bosinger, Bjoern Peters, Steven H Kleinstein, Elaine F Reed, Alison D Augustine, Joann Diray-Arce, Holden T Maecker, Matthew C Altman, Ruth R Montgomery, Patrice M Becker, Nadine Rouphael

Faculty, Staff and Students Publications

Post-acute sequelae of SARS-CoV-2 (PASC) is a significant public health concern. We describe Patient Reported Outcomes (PROs) on 590 participants prospectively assessed from hospital admission for COVID-19 through one year after discharge. Modeling identified 4 PRO clusters based on reported deficits (minimal, physical, mental/cognitive, and multidomain), supporting heterogenous clinical presentations in PASC, with sub-phenotypes associated with female sex and distinctive comorbidities. During the acute phase of disease, a higher respiratory SARS-CoV-2 viral burden and lower Receptor Binding Domain and Spike antibody titers were associated with both the physical predominant and the multidomain deficit clusters. A lower frequency of circulating B …

Effect Of Anti-Interleukin-6 Agents On Psychopathology In A Sample Of Patients With Post-Covid-19 Syndrome: An Observational Study, Alessio Simonetti, Antonio Restaino, Evelina Bernardi, Ottavia Marianna Ferrara, Stella Margoni, Antonio Maria D'Onofrio, Federica Ranieri, Delfina Janiri, Vincenzo Galluzzo, Matteo Tosato, Georgios D Kotzalidis, Francesco Landi, Gabriele Sani

Faculty, Staff and Students Publications

Interleukin 6 (IL-6) receptor inhibitors tocilizumab and sarilumab have recently been approved for severe coronavirus disease 2019 (COVID-19). They also affect mood, even though their effect on the post-COVID-19 syndrome-related psychopathology still has to be investigated. The aim of this study was to investigate their effect on psychopathology in a sample of patients with post-COVID-19 syndrome. We included 246 patients (34% female, 66% male) aged 18–75 years who had been hospitalized for COVID. Patients were split into those who received anti-IL-6 receptor agents (Anti-IL-6-R, N = 88) and those who did not (Ctrl, N = 158). The former group was …

Heat Shock Factor 1 Directly Regulates Transsulfuration Pathway To Promote Prostate Cancer Proliferation And Survival, J Spencer Hauck, David Moon, Xue Jiang, Mu-En Wang, Yue Zhao, Lingfan Xu, Holly Quang, William Butler, Ming Chen, Everardo Macias, Xia Gao, Yiping He, Jiaoti Huang

Faculty, Staff and Students Publications

There are limited therapeutic options for patients with advanced prostate cancer (PCa). We previously found that heat shock factor 1 (HSF1) expression is increased in PCa and is an actionable target. In this manuscript, we identify that HSF1 regulates the conversion of homocysteine to cystathionine in the transsulfuration pathway by altering levels of cystathionine-β-synthase (CBS). We find that HSF1 directly binds the CBS gene and upregulates CBS mRNA levels. Targeting CBS decreases PCa growth and induces tumor cell death while benign prostate cells are largely unaffected. Combined inhibition of HSF1 and CBS results in more pronounced inhibition of PCa cell …

"Once I Take That One Bite": The Consideration Of Harm Reduction As A Strategy To Support Dietary Change For Patients With Diabetes, Alexzandra Gentsch, Megan Reed, Amy Cunningham, Anna Marie Chang, Stephanie Kahn, Danielle Kovalsky, Amanda Doty, Geoffrey Mills, Judd Hollander, Kristin Rising

College of Population Health Faculty Papers

BACKGROUND: Despite well-established guidelines to treat diabetes, many people with diabetes struggle to manage their disease. For many, this struggle is related to challenges achieving nutrition-related lifestyle changes. We examined how people with diabetes describe barriers to maintaining a healthy diet and considered the benefits of using a harm reduction approach to assist patients to achieve nutrition-related goals.

METHODS: This is a secondary analysis of 89 interviews conducted with adults who had type 1 or type 2 diabetes. Interviews were analyzed using a content analysis approach. Themes regarding food or diet were initially captured in a "food" node. Data in …

Inpatient Costs Of Treating Patients With Covid-19, Kandice A Kapinos, Richard M Peters, Robert E Murphy, Samuel F Hohmann, Ankita Podichetty, Raymond S Greenberg

Faculty, Staff and Student Publications

IMPORTANCE: With more than 6.2 million hospitalizations due to COVID-19 in the US, recognition of the average hospital costs to provide inpatient care during the pandemic is necessary to understanding the national medical resource use and improving public health readiness and related policies.

OBJECTIVE: To examine the mean cost to provide inpatient care to treat COVID-19 and how it varied through the pandemic waves and by important sociodemographic patient characteristics.

DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional study used inpatient-level data from March 1, 2020, to March 31, 2022, extracted from a repository of clinical, administrative, and financial information covering 97% …

Urban School Neighbourhoods Dominated By Unhealthy Food Retailers And Advertisements In Greater Tunis: A Geospatial Study In The Midst Of The Nutrition Transition, Christelle Akl, Nehmat El-Helou, Gloria Safadi, Aline Semaan, Aya El Sammak, Tarek Trabelsi, Sonia Sassi, Chaza Akik, Jalila El Ati, Pierre Traissac, Hala Ghattas Ph.D.

Faculty Publications

Objective:

Food environments are a major determinant of children’s nutritional status. Scarce evidence on food environments exists in low- and middle-income countries (LMIC). This study aims to fill this gap by documenting the obesogenicity of food environments around schools in Greater Tunis, Tunisia – an LMIC of the Middle East and North Africa region with an ongoing nutrition transition and increasing rates of childhood obesity.

Design:

In this cross-sectional study, we assessed built food environments around fifty primary schools. Ground-truthing was performed to collect geographic coordinates and pictures of food retailers and food advertisement sets within an 800-m road network …

Patient Priorities-Aligned Care For Older Adults With Multiple Conditions: A Nonrandomized Controlled Trial, Mary E Tinetti, Ardeshir Hashmi, Henry Ng, Margaret Doyle, Toyomi Goto, Jessica Esterson, Aanand D Naik, Lilian Dindo, Fan Li

Faculty, Staff and Student Publications

IMPORTANCE: Older adults with multiple conditions receive health care that may be burdensome, of uncertain benefit, and not focused on what matters to them. Identifying and aligning care with patients' health priorities may improve outcomes.

OBJECTIVE: to assess the association of receiving patient priorities care (PPC) vs usual care (UC) with relevant clinical outcomes.

DESIGN, SETTING, AND PARTICIPANTS: In this nonrandomized controlled trial with propensity adjustment, enrollment occurred between August 21, 2020, and May 14, 2021, with follow-up continuing through February 26, 2022. Patients who were aged 65 years or older and with 3 or more chronic conditions were enrolled …

Physical Activity And Its Association With Academic Performance Among Malaysian Adolescents, Vinura Venugopal

Student Works (2020-2029)

The rates of physical inactivity among adolescents have been increasing yearly. Physical activity can reduce the risk of diseases, help manage weight, improve brain health, and ensure healthy growth and development. Besides these benefits, physical activity has also been linked to better academic achievement in certain studies. This study examines the relationship between physical activity and academic performance (national-based examinations) among adolescents in Malaysia. It was also designed to identify a feasible standardised physical activity programme. Methods: This is a multimethod study. The first phase is a prospective closed cohort study using data from 579 students from the Malaysian Health …

Clonal Hematopoiesis And Incident Heart Failure With Preserved Ejection Fraction, Art Schuermans, Michael C Honigberg, Laura M Raffield, Bing Yu, Mary B Roberts, Charles Kooperberg, Pinkal Desai, April P Carson, Amil M Shah, Christie M Ballantyne, Alexander G Bick, Pradeep Natarajan, Joann E Manson, Eric A Whitsel, Charles B Eaton, Alexander P Reiner

Faculty, Staff and Student Publications

IMPORTANCE: Clonal hematopoiesis of indeterminate potential (CHIP), the age-related clonal expansion of hematopoietic stem cells with leukemogenic acquired genetic variants, is associated with incident heart failure (HF).

OBJECTIVE: To evaluate the associations of CHIP and key gene-specific CHIP subtypes with incident HF with preserved ejection fraction (HFpEF) and reduced ejection fraction (HFrEF).

DESIGN, SETTING, AND PARTICIPANTS: This population-based cohort study included participants from 2 racially diverse prospective cohort studies with uniform HF subtype adjudication: the Jackson Heart Study (JHS) and Women's Health Initiative (WHI). JHS participants were enrolled during 2000 to 2004 and followed up through 2016. WHI participants were …

Microbial Co-Occurrences On Catheters From Long-Term Catheterized Patients, Taylor M Nye, Zongsen Zou, Chloe L P Obernuefemann, Jerome S Pinkner, Erin Lowry, Kent Kleinschmidt, Karla Bergeron, Aleksandra Klim, Karen W Dodson, Ana L Flores-Mireles, Jennifer N Walker, Daniel Garrett Wong, Alana Desai, Michael G Caparon, Scott J Hultgren

Faculty, Staff and Student Publications

Catheter-associated urinary tract infections (CAUTIs), a common cause of healthcare-associated infections, are caused by a diverse array of pathogens that are increasingly becoming antibiotic resistant. We analyze the microbial occurrences in catheter and urine samples from 55 human long-term catheterized patients collected over one year. Although most of these patients were prescribed antibiotics over several collection periods, their catheter samples remain colonized by one or more bacterial species. Examination of a total of 366 catheter and urine samples identify 13 positive and 13 negative genus co-occurrences over 12 collection periods, representing associations that occur more or less frequently than expected …

Cell State Of Origin Impacts Development Of Distinct Endometriosis-Related Ovarian Carcinoma Histotypes, Ian Beddows, Huihui Fan, Karolin Heinze, Benjamin K Johnson, Anna Leonova, Janine Senz, Svetlana Djirackor, Kathleen R Cho, Celeste Leigh Pearce, David G Huntsman, Michael S Anglesio, Hui Shen

Faculty, Staff and Student Publications

Clear cell ovarian carcinoma (CCOC) and endometrioid ovarian carcinoma (ENOC) are ovarian carcinoma histotypes, which are both thought to arise from ectopic endometrial (or endometrial-like) cells through an endometriosis intermediate. How the same cell type of origin gives rise to two morphologically and biologically different histotypes has been perplexing, particularly given that recurrent genetic mutations are common to both and present in nonmalignant precursors. We used RNA transcription analysis to show that the expression profiles of CCOC and ENOC resemble those of normal endometrium at secretory and proliferative phases of the menstrual cycle, respectively. DNA methylation at the promoter of …

Integrated Multi-Omics Analyses Identify Anti-Viral Host Factors And Pathways Controlling Sars-Cov-2 Infection, Jiakai Hou, Yanjun Wei, Jing Zou, Roshni Jaffery, Long Sun, Shaoheng Liang, Ningbo Zheng, Ashley M Guerrero, Nicholas A Egan, Ritu Bohat, Si Chen, Caishang Zheng, Xiaobo Mao, S Stephen Yi, Ken Chen, Daniel J Mcgrail, Nidhi Sahni, Pei-Yong Shi, Yiwen Chen, Xuping Xie, Weiyi Peng

Faculty, Staff and Student Publications

Host anti-viral factors are essential for controlling SARS-CoV-2 infection but remain largely unknown due to the biases of previous large-scale studies toward pro-viral host factors. To fill in this knowledge gap, we perform a genome-wide CRISPR dropout screen and integrate analyses of the multi-omics data of the CRISPR screen, genome-wide association studies, single-cell RNA-Seq, and host-virus proteins or protein/RNA interactome. This study uncovers many host factors that are currently underappreciated, including the components of V-ATPases, ESCRT, and N-glycosylation pathways that modulate viral entry and/or replication. The cohesin complex is also identified as an anti-viral pathway, suggesting an important role of …

Neurocystecercosis, Sudha Kiran Das Dr, Vipul Malviya Dr, Sachin P. Shetty Dr, Shrisagar R A

Radiology Teaching Files

• 42 year male patient presented with complains of generalised weakness and 2 episodes of seizures. CT and MRI brain was performed and was diagnosed with neurocystecercosis. Symptomatic treatment with antiseizure medications, along with anthelmintic therapy using albendazole and praziquantel, the two antiparasitics, was planned, accompanied by corticosteroids.

Unveiling A Hidden Peril: Unanticipated Emergence Of Diaphragmatic Hernia After Trauma, Deepak Benny Dr, Deepak K. S Dr, Vishal S. Dharpur Dr, Priyanshi Tapadia

Radiology Teaching Files

This case report presents a rare instance of a delayed diagnosis of obstructed diaphragmatic hernia in a 57-year-old male, a year after sustaining trauma. The patient initially presented with abdominal pain and obstipation, without any overt signs of diaphragmatic injury. Diagnostic challenges were compounded by the patient's non-specific symptomatology and the absence of immediate post-traumatic complications. The report discusses the clinical presentation, diagnostic imaging, and therapeutic management, underscoring the importance of considering diaphragmatic hernia in differential diagnoses of abdominal pain post-trauma. The case highlights the necessity for heightened clinical vigilance and the pivotal role of advanced imaging techniques in diagnosing …

Unveiling The Silent Specter: A Comprehensive Exploration Of Silent Sinus Syndrome, Deepak Benny Dr, Sudha Kiran Das Dr, Shwetha R. Poojary Dr, Priyanshi Tapadia

Radiology Teaching Files

A 42-year-old individual presented to the outpatient clinic with subtle facial asymmetry noted over the past year, primarily characterized by a progressive, painless sinking of the right eye (enophthalmos). The patient reported a history of mild, intermittent nasal obstruction but no acute sinus infections, significant nasal discharge, or facial pain. Despite these mild symptoms, the patient expressed concern over the noticeable change in facial appearance and occasional double vision, which prompted a visit to the clinic.The patient described a gradual onset of the right eye appearing "sunken" without any preceding trauma, infection, or significant weight loss. Initially dismissed as a …

Pericallosal Lipoma Unveiled: A Rare Case Of Incidental Discovery And Its Clinical Implications, Deepak Benny Dr, Sachin P. Shetty Dr, Kavitha B. C Dr, Sinchana N Dr

Radiology Teaching Files

This case report delves into the incidental finding of a pericallosal lipoma during routine neuroimaging conducted for non-specific neurological symptoms. It provides a detailed examination of the lipoma's radiological features, outlines the clinical significance of such findings, and discusses the management approach adopted, including considerations for surgical intervention versus conservative monitoring. The report further explores the implications of incidental pericallosal lipomas on patient outcomes, emphasizing the need for awareness among clinicians about this rare condition and the importance of individualized patient care strategies in the context of such incidental neuroimaging discoveries.

Emerging Mania In Young Adulthood: A Case Report Of Idiopathic Fahr's Syndrome Unveiling Neuropsychiatric Dimensions, Deepak Benny Dr, Shwetha R. Poojary Dr, Kavya B. T Dr, Sudha Kiran Das Dr.

Radiology Teaching Files

This case report outlines the diagnosis and management of an 18-year-old male presenting with first episode mania, attributed to idiopathic Fahr's Syndrome. Despite having no significant past medical or psychiatric history, the patient exhibited classic manic symptoms alongside grandiose delusions. Notably, CT imaging revealed brain calcifications characteristic of Fahr's Syndrome, absent metabolic disturbances commonly associated with the disorder. This case underscores the clinical complexity of Fahr's Syndrome, illustrating its potential to manifest primarily with psychiatric symptoms and the importance of integrating neuroimaging in the psychiatric evaluation to uncover underlying neurological disorders.

Pulmonary Infarction, Manu Chaudhary Dr, Sachin P. Shetty Dr, Sinchana N Dr

Radiology Teaching Files

68 years old female presented with breathlessness and chest pain to EMD, on clinical examination her saturation was low and D-Dimer levels were significantly elevated raising the possibility of pulmonary thromboembolism. Further the patient was referred for chest radiograph and CT thorax with contrast for better evaluation and was diagnosed with pulmonary thromboembolism with pulmonary infarct. The patient was treated for the same.

Examining The Effects Of Manualized Suicide Intervention Training On Clinical Psychology Doctoral Trainees: A Quasi-Experimental Trial, Alexander Dorfman M.S.

Selected Full Text Dissertations, 2011-

Although most clinical psychology doctoral trainees encounter at least one suicidal client over the course of their training (Dexter-Mazza & Freeman, 2003), there is notable variability in the degree of formal suicide risk assessment and intervention training offered across clinical psychology doctoral programs (Monahan & Karver, 2021). Most suicide-related training involves passive (e.g., lectures) rather than active (e.g., role-plays, experiential exercises) training techniques, despite evidence for the effectiveness of the latter in improving clinicians’ skills (Gryglewicz et al., 2020). The Applied Suicide Intervention Skills Training (ASIST) is a manualized, evidence-based training incorporating didactics and role-plays (LivingWorks, 2013; Rodgers, 2010). The …

Dengueseq: A Pan-Serotype Whole Genome Amplicon Sequencing Protocol For Dengue Virus, Chantal B. F. Vogels, Verity Hill, Mallery I. Breban, Chrispin Chaguza, Lauren M. Paul, Afeez Sodeinde, Emma Taylor-Salmon, Isabel M. Ott, Mary E. Petrone, Dennis Dijk, Marcel Jonges, Matthijs R. A. Welkers, Timothy Locksmith, Yibo Dong, Namratha Tarigopula, Omer Tekin, Sarah Schmedes, Sylvia Bunch, Natalia Cano, Rayah Jaber, Charles Panzera, Ian Stryker, Julieta Vergara, Rebecca Zimler, Edgar Kopp, Lea Heberlein, Kaylee Herzog, Joseph R. Fauver, Andrea M. Morrison, Scott F. Michael, Nathan D. Grubaugh

Journal Articles: Epidemiology

BACKGROUND: The increasing burden of dengue virus on public health due to more explosive and frequent outbreaks highlights the need for improved surveillance and control. Genomic surveillance of dengue virus not only provides important insights into the emergence and spread of genetically diverse serotypes and genotypes, but it is also critical to monitor the effectiveness of newly implemented control strategies. Here, we present DengueSeq, an amplicon sequencing protocol, which enables whole-genome sequencing of all four dengue virus serotypes.

RESULTS: We developed primer schemes for the four dengue virus serotypes, which can be combined into a pan-serotype approach. We validated both …

Impact Of Education As A Social Determinant On The Risk Of Type 2 Diabetes Mellitus In Korean Adults, Mi-Joon Lee, Bum-Jeun Seo, Yeon-Sook Kim

Health Science and Human Ecology Faculty Publications

Education is correlated with health literacy, which is a combination of reading and listening skills, data analysis, and decision-making during the necessary health situations. This study aims to evaluate the effect of education on the risk of type 2 diabetes mellitus (T2DM). This is a population-based cross-sectional study using the 2019 nationwide survey data in Korea. There were 3951 study subjects, after excluding participants with missing data for key exposures and outcome variables. Descriptive statistics, χ2 (chi-square) test, and logistic regression were performed to analyze the data. The prevalence of T2DM was associated with educational attainment, sex, age, smoking status, …

An Uncommon Culprit In Sma Syndrome: Navigating Through Duodenal Adenocarcinoma-Induced Obstruction, Deepak Benny Dr, Vikram Patil, Shrisagar R A

Radiology Teaching Files

Superior Mesenteric Artery (SMA) Syndrome is an infrequent vascular compression disorder, characterized predominantly by the extrinsic obstruction of the third part of the duodenum by the SMA, leading to a spectrum of gastrointestinal symptoms. While most commonly associated with rapid weight loss and anatomical variations, its occurrence in the context of adjacent malignancies remains exceedingly rare and clinically significant.

Here I detail a compelling case of a 49-year-old male, initially presenting with nonspecific symptoms of intermittent abdominal pain and vomiting. The diagnostic journey, propelled by computed tomography (CT) and subsequent investigations, unveiled an underlying duodenal adenocarcinoma exerting extrinsic pressure, precipitating …

The Influence Of Cultural Factors On Health-Seeking Behaviors Regarding Prostate Cancer Among African Immigrant Men In The United States., Kaitlin Van Voorhis, Ernest Kaninjing, Rae Walker, M E. Ogunsanya, G Asiedu, A Kokayi, M E. Young, F T. Odedina

Graduate Research Showcase

Background: African immigrants represent a rapidly growing segment of the United States immigrant population reshaping the rich diversity of US Blacks. Despite this growth, there is a dearth of research examining the impact of immigration on this subpopulation, particularly regarding chronic diseases like cancer. Little is published about whether SSAIs adapt to health behaviors more common in their new setting or remain immersed in the values, beliefs, and practices reflective of their culture of origin. To better understand drivers of health disparities in prostate cancer outcomes among Blacks, this study explored cultural factors among SSAIs to illuminate the health …

The Impact Of Permit Concealed Carry And Social Factors On Firearm Fatalities, Witty Kwok, Jacob Weaver

Scholarship in Medicine - All Papers

A tragic amount of gun fatalities occur in today's world. These fatalities can be from acts of aggression, negligence, or accidental, but nonetheless are taking lives at an alarming rate. There has been a call to action to make changes and begin combating these issues, with the most commonly proposed solution being firearm regulation. This study aimed to assess the effectiveness of firearm legislation, specifically of concealed carry regulations, on controlling firearm fatalities while also attempting to identify underlying causes or predictors of firearm fatalities. In an attempt to simplify the many regulations implemented differently between states, this study looked …

A Study Into Exercise And Obesity On Diabetes In Ohio, Colorado, And Mississippi, Grace Li, Wafiq Choudhury

Scholarship in Medicine - All Papers

Type 2 diabetes has become an epidemic in the US adult population, with its prevalence increasing every year. The disease is associated with physical inactivity and obesity. Like other lifestyle diseases, type 2 diabetes is preventable and manageable. Previous studies have shown that exercise plays an important role in diabetes treatment. In this study, we aimed to investigate relationships among obesity rate, access to exercise opportunities, and diabetes prevalence in Ohio, Colorado, and Mississippi by analyzing County Health Rankings data of the three states from 2016 and 2022. Our results showed associations among obesity rate, access to exercise opportunities, and …

Factors Affecting Health Outcomes In Ohio’S Most Populated Rural And Urban Counties, Isaac Stokes, Omar Sarhan

Scholarship in Medicine - All Papers

Background: Citizens of Ohio live in a diverse range of settings, such as urban, metropolitan, and rural counties. Populations living in urban settings may live longer and have more access to healthcare providers (Primary Care and Mental Health). Due to the improved access of care, populations in the urban settings may have less hospital visits and overall, better health compared to rural counties within Ohio. Objective: The objective of this investigation was to examine the urban and rural counties in the state for differences in years of potential life lost, primary care physician ratio, preventable hospitalization stays, and mental health …

Analyzing The Correlation Between Water Violations And Hospitalization Rates, Rebekah Dalton, Jed Speers

Scholarship in Medicine - All Papers

Unsafe water due to violations in water safety can result in illness and ultimately hospitalization. However, there is little data that analyzes regional rates of water violations and their correlation to hospitalization rates. This research aims to analyze the correlation between water violations and hospitalization rates between the Midwest, East and West Coasts, and between Ohio counties that use the Lake Erie water basin and those that use the Ohio River water basin. Methods include the use of data from County Health Rankings and the following statistical tests: paired and unpaired T-tests, ANOVA, and Pearson Correlation test. Results showed that …

Practice Patterns And Medical Provider Perceptions Of Ketamine In The Treatment Of Psychiatric Disorders: A Nationwide Survey, Amna M. Aslam

Theses and Dissertations

Background: Major Depressive Disorder (MDD) significantly impacts society, with a prevalence of 8.4% in the U.S., highlighting the need for effective treatments for treatment-resistant depression (TRD). Ketamine, while not FDA-approved for TRD, shows promise in treating mental health disorders and is used in specialized clinics, though evidence of effectiveness is scarce. Objectives: This study investigates the use of off-label ketamine for TRD and other disorders, focusing on ketamine clinic operations where the drug is administered, treatment methods, patient characteristics, and ketamine's impact on psychiatric care, from providers' perspectives. Methods: The survey was distributed to over 1,000 ketamine providers across the …

Incorporation Of Nutrition Education With Medication Injection To Sustain Weight Loss, Julia Calvelo

Nursing | Senior Theses

Background: Obesity is a widespread occurrence linked to comorbidities. Weight loss and maintenance is crucial to sustain existing health conditions and reduce risk of chronic diseases.

Lack of maintained weight loss is associated with poor education on nutrition, diet, and physical activity literacy. Objective: The purpose of this quantitative experimental study is to determine the efficacy of nutrition education among medication injection to sustain weight loss throughout treatment. It aims to promote comprehension of the aspects of nutrition, dietary habits, and physical education to not only sustain weight loss, but to understand the significance of how these elements contribute to …