Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Medical Specialties (1111)
- Social and Behavioral Sciences (987)
- Education (827)
- Life Sciences (691)
- Medical Sciences (686)
-
- Public Health Education and Promotion (603)
- Health Services Research (493)
- Medical Education (483)
- Community Health and Preventive Medicine (472)
- Health and Physical Education (468)
- Epidemiology (442)
- Diseases (435)
- Mental and Social Health (429)
- Women's Health (300)
- Curriculum and Instruction (280)
- Kinesiology (257)
- Patient Safety (251)
- Exercise Science (245)
- Sports Studies (242)
- Oncology (234)
- Health and Medical Administration (225)
- COVID-19 (221)
- Physical Sciences and Mathematics (205)
- Sociology (202)
- Maternal and Child Health (188)
- Nursing (186)
- Library and Information Science (161)
- Health Sciences and Medical Librarianship (153)
- Institution
-
- The Texas Medical Center Library (875)
- Wayne State University (266)
- Boise State University (242)
- Universitas Indonesia (175)
- Children's Health Medical Center Dallas (151)
-
- LSU Health New Orleans (134)
- Walden University (117)
- University of Kentucky (110)
- Thomas Jefferson University (109)
- University of Nebraska Medical Center (98)
- Rowan University (91)
- University of South Carolina (87)
- Roseman University of Health Sciences (80)
- Edith Cowan University (79)
- Aga Khan University (77)
- University of Texas Rio Grande Valley (51)
- JSS Academy of Higher Education and Research (45)
- Portland State University (44)
- Georgia Southern University (37)
- Yale University (36)
- Chulalongkorn University (31)
- Old Dominion University (31)
- Chapman University (30)
- Dominican University of California (29)
- The Beryl Institute (28)
- City University of New York (CUNY) (27)
- Institut de Recherche Robert-Sauvé en santé et en sécurité du travail (27)
- The University of San Francisco (26)
- University of Nebraska - Lincoln (26)
- University of Nevada, Las Vegas (26)
- Keyword
-
- Humans (712)
- Female (430)
- Male (324)
- Adult (257)
- COVID-19 (218)
-
- Middle Aged (197)
- Health (180)
- Aged (163)
- Health literacy (162)
- Activities (150)
- Coloring book (150)
- United States (135)
- Child (102)
- SARS-CoV-2 (99)
- Adolescent (97)
- Animals (95)
- Pregnancy (88)
- Young Adult (79)
- Risk Factors (76)
- Mental health (74)
- Public health (68)
- Mice (67)
- Retrospective Studies (57)
- Cross-Sectional Studies (56)
- Depression (56)
- Epidemiology (55)
- Infant (55)
- Obesity (53)
- Hospital (49)
- Communication (48)
- Publication
-
- Faculty, Staff and Student Publications (562)
- Faculty, Staff and Students Publications (296)
- Patient Education Projects (255)
- International Journal of Physical Activity and Health (232)
- Walden Dissertations and Doctoral Studies (109)
-
- Annual Research Symposium (80)
- Rowan-Virtua Research Day (79)
- English (75)
- Spanish (75)
- Research outputs 2022 to 2026 (72)
- School of Medicine Faculty Publications (72)
- Faculty Publications (58)
- Capstone Experience: Master of Public Health (50)
- Kesmas (47)
- Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.) (46)
- Theses and Dissertations (37)
- Digital Journal of Clinical Medicine (36)
- Public Health Theses (36)
- Electronic Theses and Dissertations (33)
- Patient Experience Journal (28)
- School of Public Health Faculty Publications (28)
- Jurnal Epidemiologi Kesehatan Indonesia (24)
- Centre of Excellence in Women and Child Health (22)
- OHSU-PSU School of Public Health Annual Conference (21)
- Preventia: The Indonesian Journal of Public Health (21)
- The Journal of the Michigan Dental Association (20)
- USF Tampa Graduate Theses and Dissertations (20)
- College of Population Health Faculty Papers (19)
- Journal of Public Health in the Deep South (19)
- Master's Projects and Capstones (19)
- Publication Type
- File Type
Articles 1711 - 1740 of 4171
Full-Text Articles in Public Health
Foster Parents Assisting Transitioning Foster Care Youth In Maintaining Stable Housing, Cecilann Morrison
Foster Parents Assisting Transitioning Foster Care Youth In Maintaining Stable Housing, Cecilann Morrison
Walden Dissertations and Doctoral Studies
Foster Parents Assisting Transitioning Foster Care Youth in Maintaining Stable Housing by Cecilann Morrison MA, National University, 2013 BS, Fresno Pacific University, 2011 Dissertation Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy Human and Social Service Walden University June 2024
Facebook’S Shared Articles On Hpv Vaccination: Analysis Of Persuasive Strategies, Ashley Hedrick Mckenzie, Elaine Avshman, Ross Shegog, Lara S Savas, L Aubree Shay
Facebook’S Shared Articles On Hpv Vaccination: Analysis Of Persuasive Strategies, Ashley Hedrick Mckenzie, Elaine Avshman, Ross Shegog, Lara S Savas, L Aubree Shay
Faculty, Staff and Student Publications
Background: The current study analyzed articles shared on Facebook between 2019 and 2021 that discuss the HPV vaccine. Results address a gap in knowledge about the persuasive strategies used in HPV vaccine discourse on Facebook.
Methods: Using Buzzsumo.com, we collected 138 articles, shared on Facebook between 2019 and 2021, with the highest "engagement scores," or total number of reactions, comments, and shares. Using a content analysis methodology, three independent coders were trained in using the study codebook, achieved acceptable inter-rater reliability (Krippendorf's alpha = 0.811), and coded each article in Atlas.ti.
Results: Seventy-two articles had a positive valence toward the …
Mental Health Assessments For Fetal Interventions, Sindhura Vangala, Roy Williams, Cara M Buskmiller, Jessian L Munoz
Mental Health Assessments For Fetal Interventions, Sindhura Vangala, Roy Williams, Cara M Buskmiller, Jessian L Munoz
Faculty, Staff and Students Publications
No abstract provided.
The Impact Of Childhood Adversity On Life Course Alcohol Use Patterns And Health Status Among People Living With Hiv, Rayna E. Gasik, Aubrey Spriggs Madkour, Simone J. Skeen, Gretchen Clum, Tishawn Francis, Erica Felker-Kantor, Tekeda Ferguson, David A. Welsh, Patricia E. Molina, Katherine P. Theall
The Impact Of Childhood Adversity On Life Course Alcohol Use Patterns And Health Status Among People Living With Hiv, Rayna E. Gasik, Aubrey Spriggs Madkour, Simone J. Skeen, Gretchen Clum, Tishawn Francis, Erica Felker-Kantor, Tekeda Ferguson, David A. Welsh, Patricia E. Molina, Katherine P. Theall
School of Public Health Faculty Publications
Adverse childhood experiences (ACEs) and financial hardship are associated with increased likelihood of heavier alcohol use and health challenges in adulthood among persons living with HIV (PWH). We examined whether retrospectively captured lifetime drinking trajectories are a pathway through which childhood hardships affect current health in a sample of 365 adult PWH. Childhood economic hardship and ACEs were used as main predictors. Measures of alcohol use included age at first drink and lifetime drinking trajectories. Health indicators included health-related quality of life, frailty, number of comorbidities, and symptoms of anxiety, depression, and post-traumatic stress disorder (PTSD). Structural equation modeling (SEM) …
Development Of An Educational Brochure About Treatment Options For Pregnant Women With Opioid Use Disorders, Ruth Jeminiwa, Sohyeon Park, Caroline Popielaski, Meghan Gannon, Ronald Myers, Diane J. Abatemarco
Development Of An Educational Brochure About Treatment Options For Pregnant Women With Opioid Use Disorders, Ruth Jeminiwa, Sohyeon Park, Caroline Popielaski, Meghan Gannon, Ronald Myers, Diane J. Abatemarco
College of Pharmacy Faculty Papers
The goal of this study was to describe the development of an educational brochure for pregnant women with opioid use disorders (OUDs) about treatment options. Based on findings from a preliminary review of the literature, we drafted a brochure that addressed the following questions: (1) What are your options (Medication-Assisted Treatment (MAT) versus no treatment)? (2) What are the benefits of MAT? (3) What are the risks of MAT? (4) Can I take buprenorphine or methadone while breastfeeding? (5) Which medication should I choose? Clinicians and doulas (n = 19) who provide care to pregnant women with OUDs were recruited. …
Understanding Organ Donation Messaging: A Qualitative Inquiry, Rebecca K. Britt, Amy A. Ritchart
Understanding Organ Donation Messaging: A Qualitative Inquiry, Rebecca K. Britt, Amy A. Ritchart
The Qualitative Report
Promoting health communication about organ donation remains a crucial objective within Native American communities. The goals of the current study were to communicate with young adult Native Americans about the Organ Donation Willingness Model (ODWM; Horton & Horton, 1991) to gain their responses to materials from campaigns about donation strategies tailored to Native American communities. Six focus groups were conducted with a total of 31 participants. Data were analyzed using thematic analysis (Braun & Clarke, 2019, 2022) and following Smith’s guidelines (2008), which include showing deep respect for the group participants, conducting the study in a face-to-face setting, and being …
Investigating Risk Factors For Racial Disparity In E-Cigarette Use With Path Study, Amy Liu, Kennedy Dorsey, Almetra Granger, Ty Runet Bryant, Tung Sung Tseng, Michael Celestin, Qingzhao Yu
Investigating Risk Factors For Racial Disparity In E-Cigarette Use With Path Study, Amy Liu, Kennedy Dorsey, Almetra Granger, Ty Runet Bryant, Tung Sung Tseng, Michael Celestin, Qingzhao Yu
School of Public Health Faculty Publications
Background: Previous research has identified differences in e-cigarette use and socioeconomic factors between different racial groups However, there is little research examining specific risk factors contributing to the racial differences. Objective: This study sought to identify racial disparities in e-cigarette use and to determine risk factors that help explain these differences. Methods: We used Wave 5 (2018–2019) of the Adult Population Assessment of Tobacco and Health (PATH) Study. First, we conducted descriptive statistics of e-smoking across our risk factor variables. Next, we used multiple logistic regression to check the risk effects by adjusting all covariates. Finally, we conducted a mediation …
Adolescent Obesogenic Behaviors: The Influence Of Race/Ethnicity, Generation Status, Acculturation, And Tme Lived Outside The United States, Tien D. Vo, Alisha H. Redelfs, Mackay Graper, Lori A. Spruance
Adolescent Obesogenic Behaviors: The Influence Of Race/Ethnicity, Generation Status, Acculturation, And Tme Lived Outside The United States, Tien D. Vo, Alisha H. Redelfs, Mackay Graper, Lori A. Spruance
Journal of Social, Behavioral, and Health Sciences
Children living with obesity are at higher risk for chronic disease. Dietary behaviors, sedentary time, and physical activity contribute to the risk of developing obesity. The purpose of this research was to identify associations between acculturation and race/ethnicity influences on obesogenic behaviors in middle school students. A national convenience sample of diverse U.S. children (11–14) was recruited to participate in an online survey (N = 615). Dietary behaviors, including fruit and vegetable consumption (F/V) and sugar-sweetened beverage consumption (SSB), as well as screen time and physical activity, were quantified. Multivariable regression models (linear and logistic) were built. We analyzed …
Immunogenicity Of A Plasmodium Vivax Circumsporozoite Protein Vaccine, Eric Cruz Murphy
Immunogenicity Of A Plasmodium Vivax Circumsporozoite Protein Vaccine, Eric Cruz Murphy
USF Tampa Graduate Theses and Dissertations
Malaria is a disease of global public health importance. Improving treatment methods focus on novel antimalarial drugs to combat parasite resistance and the development of vaccines with effective adjuvants. The current vaccine RTS,S/AS01 is moderately effective only against Plasmodium falciparum. There is no vaccine for Plasmodium vivax to date. The development and implementation of a vaccine against P. vivax would inhibit sporozoite infection of hepatocytes, block development into the blood stage and confer future immune protection. The circumsporozoite protein (CSP) is the most abundant on the surface of sporozoites and protein variants VK210 and VK247 are leading vaccine candidates for …
Identifying Interventions To Improve Diagnostic Safety In Emergency Departments: Protocol For A Participatory Design Study, Woosuk Seo, Sun Young Park, Zhan Zhang, Hardeep Singh, Kalyan Pasupathy, Prashant Mahajan
Identifying Interventions To Improve Diagnostic Safety In Emergency Departments: Protocol For A Participatory Design Study, Woosuk Seo, Sun Young Park, Zhan Zhang, Hardeep Singh, Kalyan Pasupathy, Prashant Mahajan
Faculty, Staff and Students Publications
Background: Emergency departments (EDs) are complex and fast-paced clinical settings where a diagnosis is made in a time-, information-, and resource-constrained context. Thus, it is predisposed to suboptimal diagnostic outcomes, leading to errors and subsequent patient harm. Arriving at a timely and accurate diagnosis is an activity that occurs after an effective collaboration between the patient or caregiver and the clinical team within the ED. Interventions such as novel sociotechnical solutions are needed to mitigate errors and risks.
Objective: This study aims to identify challenges that frontline ED health care providers and patients face in the ED diagnostic process and …
Patrol Car Swab Sampling For Biological Agents, Haylie Corcho
Patrol Car Swab Sampling For Biological Agents, Haylie Corcho
USF Tampa Graduate Theses and Dissertations
Law enforcement personnel have a variety of responsibilities and subsequently, a variety of different exposures. Biological agents are common in the environment and therefore, these exposures are a concern in the profession. There is a gap in research into biological agent exposures in this profession, particularly how it relates to surface contamination and within the officers’ vehicles. There is also a lack of standardized decontamination procedures for patrol vehicles, allowing for the potential persistence of these agents. The purpose of this study is to understand which biological agents are most common in patrol cars, which areas within the vehicles have …
Implementation Of A Health Information Technology Safety Classification System In The Veterans Health Administration’S Informatics Patient Safety Office, Danielle Kato, Joe Lucas, Dean F Sittig
Implementation Of A Health Information Technology Safety Classification System In The Veterans Health Administration’S Informatics Patient Safety Office, Danielle Kato, Joe Lucas, Dean F Sittig
Faculty, Staff and Student Publications
Objective: Implement the 5-type health information technology (HIT) patient safety concern classification system for HIT patient safety issues reported to the Veterans Health Administration's Informatics Patient Safety Office.
Materials and methods: A team of informatics safety analysts retrospectively classified 1 year of HIT patient safety issues by type of HIT patient safety concern using consensus discussions. The processes established during retrospective classification were then applied to incoming HIT safety issues moving forward.
Results: Of 140 issues retrospectively reviewed, 124 met the classification criteria. The majority were HIT failures (eg, software defects) (33.1%) or configuration and implementation problems (29.8%). Unmet user …
Bd Vaginal Panel Assay Results On The High-Throughput Bd Cor System Compared To The Bd Max System, Elizabeth Stonebraker, Wallace Greene, Stephanie N. Taylor, Catherine L. Cammarata, April Bobenchik, Elizabeth Lockamy
Bd Vaginal Panel Assay Results On The High-Throughput Bd Cor System Compared To The Bd Max System, Elizabeth Stonebraker, Wallace Greene, Stephanie N. Taylor, Catherine L. Cammarata, April Bobenchik, Elizabeth Lockamy
School of Medicine Faculty Publications
Molecular-based assays demonstrate excellent sensitivity for the detection of vaginitis causes. Here, the high-throughput BD Vaginal Panel for BD COR System (VP-COR) performance was compared to that of the predicate, BD MAX Vaginal Panel for BD MAX System (VP-MAX). Clinical or contrived samples were used to determine the agreement between VP-COR and VP-MAX. Acceptance criteria for VP-COR agreement were as follows: bacterial vaginosis (BV) required a positive percent agreement (PPA) point estimate of ≥ 95% and a negative percent agreement (NPA) point estimate of ≥ 98%; Candida group, Candida glabrata, Candida krusei, and Trichomonas vaginalis (TV) required a PPA and …
Primary Care Payment Models And Avoidable Hospitalizations In Ontario, Canada: A Multivalued Treatment Effects Analysis., Nibene Habib Somé, Rose Anne Devlin, Nirav Mehta, Sisira Sarma
Primary Care Payment Models And Avoidable Hospitalizations In Ontario, Canada: A Multivalued Treatment Effects Analysis., Nibene Habib Somé, Rose Anne Devlin, Nirav Mehta, Sisira Sarma
Epidemiology and Biostatistics Publications
Improving access to primary care physicians' services may help reduce hospitalizations due to Ambulatory Care Sensitive Conditions (ACSCs). Ontario, Canada's most populous province, introduced blended payment models for primary care physicians in the early- to mid-2000s to increase access to primary care, preventive care, and better chronic disease management. We study the impact of payment models on avoidable hospitalizations due to two incentivized ACSCs (diabetes and congestive heart failure) and two non-incentivized ACSCs (angina and asthma). The data for our study came from health administrative data on practicing primary care physicians in Ontario between 2006 and 2015. We employ a …
Indo-Caribbean Youth And Suicidal Behavior: A Systematic Review, Raul Ruiz Camacho, Shiryn D. Sukhram
Indo-Caribbean Youth And Suicidal Behavior: A Systematic Review, Raul Ruiz Camacho, Shiryn D. Sukhram
Publications and Research
The suicide rates in Guyana, Suriname and Trinidad and Tobago are among the highest in the Americas, containing significant Indo-Caribbean populations that are suggested to be most vulnerable to suicide. This systematic review analyzes the existing literature and identifies knowledge gaps in risk and protective factors against suicide in these countries. The literature search conducted followed PRISMA guidelines using the PubMed and APA PsycInfo databases. The PRISMA flow diagram illustrated that eight scholarly papers were eligible for inclusion. Included literature examined stratified data focused on the aforementioned countries, as well as their Indo-Caribbean adolescent populations. Excluded literature did not mention …
Case Report: Dementia Sensitivity To Altitude Changes And Effective Treatment With Hyperbaric Air And Glutathione Precursors, Edward F. Fogarty, Paul G. Harch
Case Report: Dementia Sensitivity To Altitude Changes And Effective Treatment With Hyperbaric Air And Glutathione Precursors, Edward F. Fogarty, Paul G. Harch
School of Medicine Faculty Publications
A 78-year-old man with dementia experienced waxing and waning of symptoms with changes in altitude as he traveled from his home in the Rocky Mountains to lower elevations and back. To replicate the improvement in his symptoms with travel to lower elevations (higher pressure), the patient was treated with a near-identical repressurization in a hyperbaric chamber using compressed air. With four 1-h treatments at 1.3 Atmospheres Absolute (ATA) and concurrent administration of low-dose oral glutathione amino acid precursors, he recovered speech and showed improvement in activities of daily living. Regional broadcast media had documented his novel recovery. Nosocomial COVID-19 and …
Incidence Of Reportable Exertional Heat Illness During Deepwater Horizon Cleanup, Fisher R. Morris
Incidence Of Reportable Exertional Heat Illness During Deepwater Horizon Cleanup, Fisher R. Morris
USF Tampa Graduate Theses and Dissertations
The purpose of this research was to explore the relationship between incidence of recordable exertional heat illness (EHI) and daily high wet bulb globe temperature (WBGTmax) or daily high Heat Index (HImax). Additionally, the effect of the previous day’s exposure to heat stress was investigated. Illness and injury records were collected during the Deepwater Horizon oil spill response. All OSHA recordable EHI cases were extracted for study. The highest estimated WBGT and HI on the day of incident were compared to the prior day. The overall incidence of recordable EHIs was 0.74 cases/100 FTE and the incidence for exposures ≥ …
An Assessment Of A Haptic-Based Ergonomic Intervention At An Aerospace Manufacturing Facility, Chase Mcdonald
An Assessment Of A Haptic-Based Ergonomic Intervention At An Aerospace Manufacturing Facility, Chase Mcdonald
USF Tampa Graduate Theses and Dissertations
The purpose of this thesis was to evaluate the effectiveness and sustainability of a haptic-based intervention designed to reduce hand motions and, consequently, the risk of musculoskeletal disorders (MSDs) among operators in a manufacturing facility. The intervention involved using ergonomic gloves equipped with haptic feedback, intended to encourage proper hand motion and reduce unnecessary movements.
Over a six-month period, data was collected from operators wearing the haptic gloves, focusing on two key metrics: Duty Cycle and Motion Rate. These metrics were chosen to normalize the data, accounting for the variability in duration for each individual operator who wore the device. …
Examining The Cues To Action Of Christian Parents And/Or Guardians Who Are Hesitant To Vaccinate Pediatric Populations, Marcia S. Jackson
Examining The Cues To Action Of Christian Parents And/Or Guardians Who Are Hesitant To Vaccinate Pediatric Populations, Marcia S. Jackson
Doctoral Dissertations and Projects
As a result of skepticism related to vaccine administration, many newborns and children are without their standardized and recommended vaccinations due to parent and/or guardian beliefs. It is the parent and/or guardian who holds the power to vaccinate their children. Vaccine administration is one of the most successful achievements of public health intervention in the 20th century. The purpose of this study is to use a descriptive case study analysis approach to assess parents' and/or guardians' concerns, attitudes, beliefs, and intentions towards immunizations for their children (from birth to 18 years of age). Understanding the "why" and "how" concerns raised …
What Do Extension And Public Health Educators Need To Address Substance Misuse?, Lisa Washburn, Karen Franck
What Do Extension And Public Health Educators Need To Address Substance Misuse?, Lisa Washburn, Karen Franck
Journal of Extension
Limited organizational capacity has hindered Extension’s ability to address substance misuse in communities. To inform capacity-building efforts, we obtained Extension educator and health educator feedback on opportunities, challenges and resource needs using the Delphi technique. Opportunities included collaboration and partnerships with local entities. Stigma, inadequate resources, and limited knowledge and skills of educators were challenges. Top resource needs were updated youth curricula, funding, and clear guidance on what educators can do and what should be referred externally. Findings provide insights to educator perceptions and suggest additional training and resources needed to implement evidence-based approaches to address substance misuse.
The Glucosylamine Oxidation Pathway Of Vitamin C Recycling, James M. Hempe, Daniel S. Hsia, Arthur Hagar, Larry Byers
The Glucosylamine Oxidation Pathway Of Vitamin C Recycling, James M. Hempe, Daniel S. Hsia, Arthur Hagar, Larry Byers
School of Medicine Faculty Publications
The proposed glucosylamine oxidation pathway (GOP) is a two-step, intraerythrocyte, thermodynamically favorable nonenzymatic reaction that first binds glucose to the N-terminal valine of beta globin (βVal1) to form a closed-chain glucosylamine that can spontaneously reduce oxidized vitamin C to its antioxidant form. This review summarizes analytical, biochemical and clinical research supporting the existence of the GOP and the surprising hypothesis that βVal1 glucosylamine is a reducing agent that works cooperatively with reduced glutathione to dynamically regulate vitamin C recycling during naturally occurring periods of transiently or chronically elevated blood glucose and oxidant production. Rationale for the existence of the GOP …
Identifying Overdose Risk Factors For People Hospitalized With Injection Drug Use-Associated Infections In Maine, Melanie Mait, Kim Murray, Tania D. Strout, Kinna Thakarar
Identifying Overdose Risk Factors For People Hospitalized With Injection Drug Use-Associated Infections In Maine, Melanie Mait, Kim Murray, Tania D. Strout, Kinna Thakarar
Journal of Maine Medical Center
Introduction: The overdose crisis continues to be a significant problem, particularly in rural states such as Maine. The objectives of this study were to: 1) describe demographic and health characteristics and 2) identify overdose risk factors among people in Maine hospitalized with injection drug use (IDU)-associated infections.
Methods: We performed descriptive analysis of demographics, health characteristics, and injection practices, stratified by lifetime history of overdose. We conducted an exploratory logistic regression analysis, controlling for gender, homelessness, having experienced an emergency department (ED) visit in the past 3-months, and endorsement of injecting alone in the past 30 days to examine …
Clinical Trial Recruitment Of People Who Speak Languages Other Than English: A Children's Oncology Group Report, Melissa P. Beauchemin, Maria Ortega, Sheila J. Santacroce, Joanna M. Robles, Jenny Ruiz, Anurekha G. Hall, Justine M. Kahn, Cecilia Fu, Manuela Orjuela-Grimm, Grace C. Hillyer, Samrawit Solomon, Wendy Pelletier, Raul Montiel-Esparza, Lindsay J. Blazin, Cassie Kline, Alix E. Seif, Paula Aristizabal, Lena E. Winestone, Maria C. Velez
Clinical Trial Recruitment Of People Who Speak Languages Other Than English: A Children's Oncology Group Report, Melissa P. Beauchemin, Maria Ortega, Sheila J. Santacroce, Joanna M. Robles, Jenny Ruiz, Anurekha G. Hall, Justine M. Kahn, Cecilia Fu, Manuela Orjuela-Grimm, Grace C. Hillyer, Samrawit Solomon, Wendy Pelletier, Raul Montiel-Esparza, Lindsay J. Blazin, Cassie Kline, Alix E. Seif, Paula Aristizabal, Lena E. Winestone, Maria C. Velez
School of Medicine Faculty Publications
BACKGROUND: Persons who speak languages other than English are underrepresented in clinical trials, likely in part because of inadequate multilevel resources. We conducted a survey of institutions affiliated with the Children's Oncology Group (COG) to characterize current research recruitment practices and resources regarding translation and interpretation services. METHODS: In October 2022, a 20-item survey was distributed electronically to institutions affiliated with COG to assess consent practices and resources for recruiting participants who speak languages other than English to COG trials. Descriptive statistics were used to summarize responses; responses were compared by institution size and type as well as respondent role. …
Does The Use Of Double Hormone Replacement Therapy For Trauma Patient Organ Donors Improve Organ Recovery For Transplant, Eden M. Gallegos, Tanner Reed, Paige Deville, Blake Platt, Claudia Leonardi, Lillian Bellfi, Jessica Dufrene, Saad Chaudhary, John Hunt, Lance Stuke, Patrick Greiffenstein, Jonathan Schoen, Alan Marr, Anil Paramesh, Alison A. Smith
Does The Use Of Double Hormone Replacement Therapy For Trauma Patient Organ Donors Improve Organ Recovery For Transplant, Eden M. Gallegos, Tanner Reed, Paige Deville, Blake Platt, Claudia Leonardi, Lillian Bellfi, Jessica Dufrene, Saad Chaudhary, John Hunt, Lance Stuke, Patrick Greiffenstein, Jonathan Schoen, Alan Marr, Anil Paramesh, Alison A. Smith
School of Graduate Studies Faculty Publications
BACKGROUND With an ongoing demand for transplantable organs, optimization of donor management protocols, specifically in trauma populations, is important for obtaining a high yield of viable organs per patient. Endocrine management of brain-dead potential organ donors (BPODs) is controversial, leading to heterogeneous clinical management approaches. Previous studies have shown that when levothyroxine was combined with other treatments, including steroids, vasopressin, and insulin, BPODs had better organ recovery and survival outcomes were increased for transplant recipients. AIM To determine if levothyroxine use in combination with steroids in BPODs increased the number of organs donated in trauma patients. METHODS A retrospective review …
Remodeling Of Anti-Tumor Immunity With Antibodies Targeting A P53 Mutant, Dafei Chai, Junhao Wang, Chunmei Fan, Jing-Ming Lim, Xu Wang, Praveen Neeli, Xinfang Yu, Ken H Young, Yong Li
Remodeling Of Anti-Tumor Immunity With Antibodies Targeting A P53 Mutant, Dafei Chai, Junhao Wang, Chunmei Fan, Jing-Ming Lim, Xu Wang, Praveen Neeli, Xinfang Yu, Ken H Young, Yong Li
Faculty, Staff and Students Publications
BACKGROUND: p53, the most frequently mutated gene in cancer, lacks effective targeted drugs.
METHODS: We developed monoclonal antibodies (mAbs) that target a p53 hotspot mutation E285K without cross-reactivity with wild-type p53. They were delivered using lipid nanoparticles (LNPs) that encapsulate DNA plasmids. Western blot, BLI, flow cytometry, single-cell sequencing (scRNA-seq), and other methods were employed to assess the function of mAbs in vitro and in vivo.
RESULTS: These LNP-pE285K-mAbs in the IgG1 format exhibited a robust anti-tumor effect, facilitating the infiltration of immune cells, including CD8+ T, B, and NK cells. scRNA-seq revealed that IgG1 reduces immune inhibitory signaling, increases …
Slip Resistance Evaluation Of 10 Indoor Floor Surfaces, David P. Gilkey, Daniel Autenrieth, Cal Snow, Cody Hays, Sarah Girard, Lorri Birkenbuel
Slip Resistance Evaluation Of 10 Indoor Floor Surfaces, David P. Gilkey, Daniel Autenrieth, Cal Snow, Cody Hays, Sarah Girard, Lorri Birkenbuel
Safety Health & Industrial Hygiene
Slip and fall injuries and fatalities continue to be a signiϐicant problem at work and in the community. Water is the most common contaminant that reduces traction on ϐloors and other walkway surfaces resulting in a slip and fall event. This project investigated 10 common ϐlooring surfaces to assess their slip resistance when dry vs wet and coated vs uncoated. Investigators used the English XL Variable Incidence Tribometer to measure slip resistance under all conditions. Results revealed a signiϐicant (p - value < 0.05) loss of slip resistance when wet vs dry. Investigators also found signiϐicant (p - value < 0.05) increases in traction when using a coating under wet conditions. Researchers support the use of coatings for ϐloors and walkway surfaces that increase traction and reduce the chances of slip and fall events under all conditions.
Antidepressant Effect Of Enzymatic Porcine Placenta Hydrolysate In Repeated Immobilization Stress-Induced Ovariectomized Female Mice, Minsook Ye, Sharon Nguyen, Min Ju Kim, Jee Sun Hwang, Gun Won Bae, Keun-Hang Susan Yang, Insop Shim
Antidepressant Effect Of Enzymatic Porcine Placenta Hydrolysate In Repeated Immobilization Stress-Induced Ovariectomized Female Mice, Minsook Ye, Sharon Nguyen, Min Ju Kim, Jee Sun Hwang, Gun Won Bae, Keun-Hang Susan Yang, Insop Shim
Biology, Chemistry, and Environmental Sciences Faculty Articles and Research
When postmenopausal women are under stress conditions, this exacerbates mood disorders and issues with neuroimmune systems. The porcine placenta is known to relieve menopausal depression in clinical trials, but its underlying mechanisms for depression and anti-inflammatory functions remain poorly defined. The present study was designed to examine the anti-inflammatory effects of enzymatic porcine placenta hydrolysate (EPPH) on LPS-induced levels of nitric oxide (NO), prostaglandin E2 (PGE2), corticosterone (CORT), and pro-inflammatory cytokine interleukin-1 beta (IL-1β) in RAW 264.7 macrophage cells. In addition, the neurite outgrowth of PC12 cells was evaluated to examine the effects of EPPH on neurite growth. To mimic …
Prevalence And Relevant Factors Of Nocturia And Its Impact On Sleep Quality In Chinese University Students, Yakai Liu, Zhenwei Zhang, Huijie Hu, Xiangfei He, Pengchao Xu, Qifeng Dou, Cuiping Song, Huiqing Zhang, Israel Franco, Konstantinos Kamperis, Søren Rittig, Jianguo Wen
Prevalence And Relevant Factors Of Nocturia And Its Impact On Sleep Quality In Chinese University Students, Yakai Liu, Zhenwei Zhang, Huijie Hu, Xiangfei He, Pengchao Xu, Qifeng Dou, Cuiping Song, Huiqing Zhang, Israel Franco, Konstantinos Kamperis, Søren Rittig, Jianguo Wen
Faculty, Staff and Student Publications
The purpose of this study was to investigate the prevalence and relevant factors of nocturia and its impact on sleep quality in university students in Mainland China. A large-scale survey was conducted on 14,000 university students from 3 universities in Henan province, China by using an anonymous questionnaire. The questionnaire collected the information from the past six months. The relationships between the prevalence of nocturia and its relevant factors were evaluated. A total of 13,874 questionnaires were collected and 13,104 qualified for statistical analysis. A total of 659 students suffered from clinically relevant nocturia (CRN) (4.56% in male and 5.34% …
The Health Risks Of Deportation: Impacts Of Family Separation On Relationships And Wellbeing In Latinx Communities, Shantay Rhea Rocha
The Health Risks Of Deportation: Impacts Of Family Separation On Relationships And Wellbeing In Latinx Communities, Shantay Rhea Rocha
University Honors Theses
Anti-immigration policy and deportation practices create multifaceted implications for Latinx communities in the United States. A comprehensive literature review drawing from public health and immigration studies was used to examine the direct and indirect implications of separation of families due to deportation. This thesis synthesizes existing research to illuminate the health threats pertaining to Latinx wellbeing in the context of being undocumented and fearing being separated from their family. Addressing the dimensions of deportation-related health risks, policy makers, health care professionals, and community organizations can work towards promoting Latinx health and well-being in the U.S. to mitigate the health consequences …
The Cost Of Healthy Eating, Diana Prychyna
The Cost Of Healthy Eating, Diana Prychyna
University Honors Theses
Background: Each year in the United States, 15-20% of 1 million visits to the Emergency Department for Acute Heart Failure result in home discharge, with patients often experiencing adverse health outcomes within 30 days. The study, Get With the Guidelines in Emergency Department Patients With Heart Failure, utilized 'Self-Care Coaches' who meet participants via telehealth calls to discuss self-care maintenance after discharge as a strategy to mitigate adverse health outcomes; and offer provisions of resources, including a cookbook by the American Association for Heart Failure Nurses (AAHFN).
During telehealth calls, we observed gaps in self-care for retired older adults (62+), …