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Articles 331 - 360 of 2166
Full-Text Articles in Public Health
Biophysical Methods For Estimating In Vivo Body Composition: The Determination Of The Adipose Compartment, Luther E. Preuss, Frank P. Bolin
Biophysical Methods For Estimating In Vivo Body Composition: The Determination Of The Adipose Compartment, Luther E. Preuss, Frank P. Bolin
Henry Ford Hospital Medical Journal
The status of the human body's major components (adipose mass, lean mass, body water, etc) and their change with time are of clinical importance. Deviation of these body components from a stable condition may be imposed by nutrition or disease, and a return to the normal body state may be brought about by appropriate medical care. Thus accurate quantitation of these components is an important goal. This field of study can be traced to the early 1800s, with a major thrust starting in the 1940s and continuing lo the present. The last four decades have shown an accelerated development of …
Morbidity And Treatment Of Clinically Important Obesity: An Internal Medicine Perspective, J. David Fachnie
Morbidity And Treatment Of Clinically Important Obesity: An Internal Medicine Perspective, J. David Fachnie
Henry Ford Hospital Medical Journal
Obesity is defined as an excess storage of energy in the form of fat. The internist generates a differential diagnosis of etiologic factors and examines the patient carefully. Obese persons are counseled on all medical risks of obesity. Choices for treatment vary according lo the severity of the obesity, and alternative dietary treatments include a balanced-deficit diet or a very low calorie diet. Weight loss can be predicted by applying specified equations. With severe obesity, multidisciplinary treatment is needed. Anorexic agents have limited value because of their side effects and because of weight increase after discontinuing therapy. Obesity is not …
Obese Father William Meets A Physician, J. David Fachnie
Obese Father William Meets A Physician, J. David Fachnie
Henry Ford Hospital Medical Journal
No abstract provided.
Minnesota Multiphasic Personality Profiles Of The Morbidly Obese, Philip J. Lanzisera, Allan Dehorn, Carolyn Macdonald, Conni Sroka, J. David Fachnie
Minnesota Multiphasic Personality Profiles Of The Morbidly Obese, Philip J. Lanzisera, Allan Dehorn, Carolyn Macdonald, Conni Sroka, J. David Fachnie
Henry Ford Hospital Medical Journal
Minnesota Multiphasic Personality Inventory profiles of 132 morbidly obese individuals participating in a protein-sparing modified fast were examined via factor analytic methods yielding five interpretable psychometric factors. The results support the hypothesis that the morbidly obese are a psychologically heterogeneous population which can be subdivided conceptually. However, the findings fail to support the hypothesis that any particular psychopathology is intricately linked to the development of morbid obesity.
Blood Pressure Changes And Weight Changes In Hypertensive Patients In An Inner-City Clinic, A. David Goldberg, Frits Van Der Kuyp, Pamela C. Keenen
Blood Pressure Changes And Weight Changes In Hypertensive Patients In An Inner-City Clinic, A. David Goldberg, Frits Van Der Kuyp, Pamela C. Keenen
Henry Ford Hospital Medical Journal
The association of obesity and hypertension has been clearly established. Despite evidence that weight loss reduces blood pressure, this aspect of treatment is often not stressed. We studied the effects of nutritional intervention in a group of inner-city, predominantly black, hypertensive patients to determine resultant blood pressure changes. Weight reduction was achieved by 57% of the patients, with a loss of more than 4.5 kg (10 lb) in 18%. Changes in weight were highly correlated with blood pressure changes. Correlations were greater for systolic than diastolic pressures, for pressure measured in the standing than the supine position, and for men …
Surgery For Morbid Obesity: A Continuing Challenge, Brack A. Bivins, Farouck N. Obeid, H. Mathilda Horst, Victor J. Sorensen
Surgery For Morbid Obesity: A Continuing Challenge, Brack A. Bivins, Farouck N. Obeid, H. Mathilda Horst, Victor J. Sorensen
Henry Ford Hospital Medical Journal
No abstract provided.
Occurrence Of Alzheimer Disease In Michigan: An Epidemiologic Review Of Rates And Risk Factors, Christine Cole Johnson
Occurrence Of Alzheimer Disease In Michigan: An Epidemiologic Review Of Rates And Risk Factors, Christine Cole Johnson
Henry Ford Hospital Medical Journal
Alzheimer disease is a progressive degenerative neurological disorder of insidious onset characterized by the deterioration of cognitive functioning. Little is known about the etiology and epidemiology of this condition. The only risk factor consistently associated with Alzheimer disease is advancing age. As the population of the elderly continues to grow, many public agencies, including those in Michigan, are concerned about social, personal, and financial implications and seek estimates of the number of people with dementia. To date, mortality rates based on vital statistics have been noninformative because Alzheimer disease is difficult lo diagnose clinically and has been considered to be …
Conrad Ramsey Lam, Md: Henry Ford Hospital's First Heart Surgeon, Donald J. Magilligan
Conrad Ramsey Lam, Md: Henry Ford Hospital's First Heart Surgeon, Donald J. Magilligan
Henry Ford Hospital Medical Journal
No abstract provided.
A Mathematical Model Of Lung Static Pressure-Volume Relationships: Comparison Of Clinically Derived Parameters Of Elasticity, William Benish, Peggy Harper, Joseph Ward, John Popovich Jr.
A Mathematical Model Of Lung Static Pressure-Volume Relationships: Comparison Of Clinically Derived Parameters Of Elasticity, William Benish, Peggy Harper, Joseph Ward, John Popovich Jr.
Henry Ford Hospital Medical Journal
We constructed a simple model of lung distensibility in which the relationship between pressure (P) and volume (V) is of the exponential form obtained empirically: V = a+ becP , where a, b, and c are constants, and e is the base of the natural logarithm. The model lung is idealized as a frictionless diaphragm moving in a cylinder. Diaphragm movement is impeded by a variable force (F). By assuming that the rate of change of F is proportional to the inverse of the distance of the diaphragm from a maximal distance, the pressure-volume relationship assumes the above exponential form. …
Anticoagulant And Antithrombotic Therapy In Deep Venous Thrombosis And Pulmonary Embolism, Paul D. Stein
Anticoagulant And Antithrombotic Therapy In Deep Venous Thrombosis And Pulmonary Embolism, Paul D. Stein
Henry Ford Hospital Medical Journal
No abstract provided.
A Double-Blind Trial Of Protriptyline In The Treatment Of Sleep Apnea Syndrome, Edward J. Stepanski, William A. Conway, David K. Young, Frank J. Zorick, Robert M. Wittig, Thomas Roth
A Double-Blind Trial Of Protriptyline In The Treatment Of Sleep Apnea Syndrome, Edward J. Stepanski, William A. Conway, David K. Young, Frank J. Zorick, Robert M. Wittig, Thomas Roth
Henry Ford Hospital Medical Journal
Eight male subjects with sleep apnea syndrome were given placebo and protriptyline in a double-blind crossover design to evaluate the effects of protriptyline on respiration during sleep. Treatment with protriptyline produced significantly better oxygenation and significantly fewer arousals during sleep, but sleep staging was unchanged. The decreased number of respiratory events approached significance and was much greater in six of eight subjects. A rapid eye movement sleep-suppression explanation of the improvement in oxygenation is not supported. Alternative explanations of these findings are discussed.
Sleep-Wake Complaints And Their Relation To Sleep Disturbance, De Ton, Frank J. Zorick, Timothy A. Roehrs, Robert M. Wittig, Jeanne M. Sicklesteel, Thomas Roth
Sleep-Wake Complaints And Their Relation To Sleep Disturbance, De Ton, Frank J. Zorick, Timothy A. Roehrs, Robert M. Wittig, Jeanne M. Sicklesteel, Thomas Roth
Henry Ford Hospital Medical Journal
This report is a comparison of patients presenting with 1) an insomnia complaint diagnosed as no objective findings. 2) insomnia diagnosed as being associated with a psychiatric disorder, and 3) daytime sleepiness diagnosed as no objective findings. The sleep of patients with insomnia diagnosed as no objective findings is comparable to that of patients with daytime sleepiness diagnosed as no objective findings and is significantly better than that of patients with insomnia associated with a psychiatric disorder. Significant differences were found in sleep induction, sleep maintenance, and overall sleep efficiency. No major differences were found among any of the groups …
A Prospective Randomized Comparison Of A Single Antibiotic (Moxalactam) Versus Combination Therapy (Gentamicin And Clindamycin) In Penetrating Abdominal Trauma, Theodore Fifer, Farouck N. Obeid, H. Mathilda Horst, Victor J. Sorensen, Larry D. Crots, Brack A. Bivins
A Prospective Randomized Comparison Of A Single Antibiotic (Moxalactam) Versus Combination Therapy (Gentamicin And Clindamycin) In Penetrating Abdominal Trauma, Theodore Fifer, Farouck N. Obeid, H. Mathilda Horst, Victor J. Sorensen, Larry D. Crots, Brack A. Bivins
Henry Ford Hospital Medical Journal
From July 1 to December 31, 1983, 50 consecutive patients undergoing abdominal exploration for penetrating abdominal trauma from stab and gunshot wounds were prospectively randomized to receive postinjury, preoperative antibiotic coverage with moxalactam (2 g intravenously every 12 hours) or a combination of gentamicin (3 to 5 mg/kg/day in three equal doses administered every eight hours) and clindamycin (600 mg intravenously every six hours). No intraabdominal abscesses or wound infections developed, and no direct evidence of toxicity of the antibiotic regimens developed in either group. In the study group, moxalactam therapy was an effective alternative to the combination antibiotic regimen. …
Clinical Significance Of Sleep Desaturation In Hypoxemic Chronic Obstructive Pulmonary Disease: Studies In 130 Patients, William A. Conway, Meir Kryger, Richard M. Timms, George W. Williams
Clinical Significance Of Sleep Desaturation In Hypoxemic Chronic Obstructive Pulmonary Disease: Studies In 130 Patients, William A. Conway, Meir Kryger, Richard M. Timms, George W. Williams
Henry Ford Hospital Medical Journal
We studied 130 patients with hypoxemic chronic obstructive lung disease to determine if nocturnal desaturation aggravates hypoxia-induced complications. All had tests of neuropsychological and physiological function known to be affected by chronic hypoxia. Of the 130 patients, 25 had complete polysomnography and 105 had their sleep judged visually and arterial oxygen saturation recorded continuously. Severe and mild desaturation groups were defined relative to the mean for both mean and maximal sleep desaturation, and the severity of waking complications were compared. No significant differences were noted between patients with mild and severe mean desaturation or maximal desaturation for hematocrit, neuropsychological tests, …
Sleep Disorders Medicine, Thomas Roth
Sleep Disorders Medicine, Thomas Roth
Henry Ford Hospital Medical Journal
No abstract provided.
Familial Childhood Sleep Apnea, Robert M. Wittig, Frank J. Zorick, Timothy A. Roehrs, Jeanne M. Sicklesteel, Thomas Roth
Familial Childhood Sleep Apnea, Robert M. Wittig, Frank J. Zorick, Timothy A. Roehrs, Jeanne M. Sicklesteel, Thomas Roth
Henry Ford Hospital Medical Journal
We report four siblings who had polysomnographically documented sleep apnea. Two presented with the typical clinical picture of sleep apnea syndrome including daytime somnolence and snoring, had repetitive obstructive apneic episodes during sleep, and were effectively treated with upper airway surgery. The other two were asymptomatic and showed infrequent apneic episodes during sleep. This family illustrates the distinction between the sleep apnea syndrome and infrequent apneic episodes during sleep. The sleep apnea syndrome is associated with daytime symptomatology and requires treatment. The presence of apneic episodes during sleep in all four siblings has implications regarding the predisposing factors (eg, upper …
Anticoagulant Therapy, Antithrombotic Therapy, Pulmonary Embolism, And The Henry Ford Hospital Perspective, Paul D. Stein
Anticoagulant Therapy, Antithrombotic Therapy, Pulmonary Embolism, And The Henry Ford Hospital Perspective, Paul D. Stein
Henry Ford Hospital Medical Journal
No abstract provided.
Clinical Manifestations Of Acute Pulmonary Embolism: Henry Ford Hospital Experience, A Five-Year Review, Kenneth V. Leeper Jr., John Popovich Jr., Deborah Adams, Paul D. Stein
Clinical Manifestations Of Acute Pulmonary Embolism: Henry Ford Hospital Experience, A Five-Year Review, Kenneth V. Leeper Jr., John Popovich Jr., Deborah Adams, Paul D. Stein
Henry Ford Hospital Medical Journal
Clinical findings of 112 patients with angiographically proven pulmonary embolism over a five-year period were analyzed. Recent immobilization, chronic heart disease, deep venous thrombosis, malignancy, and recent surgery were the most frequent predisposing factors. Only 5% had no identifiable risk factors. Presenting syndromes were circulatory collapse (25%), pulmonary infarction (59%), and uncomplicated pulmonary embolism (18%). Dyspnea and pleuritic chest pain were the predominant symptoms. The combination of dyspnea, pleuritic chest pain, and hemoptysis occurred in 23% of the patients. The most frequent signs were tachypnea, tachycardia, and rales. Most of the patients demonstrated arterial oxygen tension (PaO2) between 50 and …
Disseminated Strongyloides Stercoralis And Aspergillus Fumigatus Presenting As Diffuse Interstitial Pneumonitis In A Steroid-Dependent Chronic Obstructive Pulmonary Disease Patient, Larry Tankanow, Michael S. Eichenhorn
Disseminated Strongyloides Stercoralis And Aspergillus Fumigatus Presenting As Diffuse Interstitial Pneumonitis In A Steroid-Dependent Chronic Obstructive Pulmonary Disease Patient, Larry Tankanow, Michael S. Eichenhorn
Henry Ford Hospital Medical Journal
We describe a patient with long-standing steroid-dependent chronic obstructive pulmonary disease who was admitted with new diffuse interstitial pulmonary infiltrates. Strongyloides stercoralis was present in the sputum and stool and responded to treatment. However, complicating disseminating Aspergillus fumigatus infection eventuated in the patient's death. Strongyloides stercoralis infection should be considered in patients with relevant exposure history, and complicating fungal and gram-negative bacterial infections which such patients may develop should be suspected.
Cancer Mortality Among Residents Of Huron, Sanilac, And Tbscola Counties As Compared To Other Michigan Residents, 1971-1985, Jennifer A. Booms, William Benish
Cancer Mortality Among Residents Of Huron, Sanilac, And Tbscola Counties As Compared To Other Michigan Residents, 1971-1985, Jennifer A. Booms, William Benish
Henry Ford Hospital Medical Journal
Age-adjusted cancer mortality rates in the "Thumb" area of Michigan (Huron, Sanilac, and Tuscola counties) were compared with those for the rest of the state from 1971 to 1985. Comparisons were made after partitioning the mortality data on the basis of the patient's sex, year of death (1971 to 1975, 1976 to 1980, or 1981 to 1985), and site of primary tumor. International Classification of Diseases categories were combined to define 29 cancer site groups. The analysis was limited to the white population. The major observation was a consistently lower mortality rate of lung cancer in the Thumb area than …
Enteric-Coated Fenoprofen In Large-Joint Osteoarthritis, Gilbert B. Bluhm, Harris H. Macilwain, Walter W. Offen
Enteric-Coated Fenoprofen In Large-Joint Osteoarthritis, Gilbert B. Bluhm, Harris H. Macilwain, Walter W. Offen
Henry Ford Hospital Medical Journal
Enteric-coated fenoprofen was compared with standard fenoprofen (Nalfon, Dista, Indianapolis, IN) in a randomized, double-blind, parallel, three-month trial of 113 outpatients (mean age, 64 years) with large-joint osteoarthritis. A previous study showed that enteric coating of fenoprofen reduces gastrointestinal microbleeding and may offer a safety advantage. Both treatments provided statistically significant improvement in pain measures (tenderness on pressure, pain at rest, pain with weight-bearing activity, and pain on passive motion). Adverse experiences were similar with both treatments and of an expected type, severity, and incidence for nonsteroidal anti-inflammatory drugs. Enteric-coated fenoprofen was found to be as effective and safe as …
Malignant Lymphoma Presenting In Gluteal Muscles: Case Report And Brief Review Of The Literature, Roberta Sonnino, Angelos A. Kambouris
Malignant Lymphoma Presenting In Gluteal Muscles: Case Report And Brief Review Of The Literature, Roberta Sonnino, Angelos A. Kambouris
Henry Ford Hospital Medical Journal
No abstract provided.
Potency Of Current Levothyroxine Preparations Evaluated By High-Performance Liquid Chromatography, Sheldon S. Stoffer, Walter E. Szpunar
Potency Of Current Levothyroxine Preparations Evaluated By High-Performance Liquid Chromatography, Sheldon S. Stoffer, Walter E. Szpunar
Henry Ford Hospital Medical Journal
Ten different levothyroxine products manufactured by six companies were analyzed by high-performance liquid chromatography. Although nine products met the United States Pharmacopeia requirements, one product was found to have only 47% of expected potency. Until these products become more uniform, we would not recommend interchangeability of levothyroxine preparations.
Jack S. Guyton, Md, Cornelius E. Mccole
Jack S. Guyton, Md, Cornelius E. Mccole
Henry Ford Hospital Medical Journal
No abstract provided.
Editorial: Responsibilities Of Authorship: Justification Of The Multiauthored Scientific Paper, Sarah Whitehouse, Raymond C. Mellinger
Editorial: Responsibilities Of Authorship: Justification Of The Multiauthored Scientific Paper, Sarah Whitehouse, Raymond C. Mellinger
Henry Ford Hospital Medical Journal
No abstract provided.
Aspects Of Endocrinology, Michael Kleerekoper, Raymond C. Mellinger
Aspects Of Endocrinology, Michael Kleerekoper, Raymond C. Mellinger
Henry Ford Hospital Medical Journal
No abstract provided.
An Overview Of Magnetic Resonance Imaging Of The Appendicular Musculoskeletal System, Sharon C. Siegel, Allan M. Haggar, Jerry W. Froelich, Burton I. Ellis
An Overview Of Magnetic Resonance Imaging Of The Appendicular Musculoskeletal System, Sharon C. Siegel, Allan M. Haggar, Jerry W. Froelich, Burton I. Ellis
Henry Ford Hospital Medical Journal
No abstract provided.
Pituitary Metastasis: Lung Cancer Presenting As Bitemporal Hemianopsia With Diabetes Insipidus And Anterior Pituitary Deficiency, A. Keith Cryar, Jay Morgan, Jack P. Rock, Max Wisgerhof
Pituitary Metastasis: Lung Cancer Presenting As Bitemporal Hemianopsia With Diabetes Insipidus And Anterior Pituitary Deficiency, A. Keith Cryar, Jay Morgan, Jack P. Rock, Max Wisgerhof
Henry Ford Hospital Medical Journal
Symptoms and signs of pituitary disease are rarely the first manifestations of malignancy originating in another organ. We present a case which exemplifies the key points that suggest a diagnosis of metastatic pituitary disease. Our patient's diagnosis was adenocarcinoma of the lung with a metastasis to the intrasellar and suprasellar regions, which caused diabetes insipidus, anterior pituitary deficiency, and visual field defects. The metastasis had a dumbbell appearance and extended from the sella turcica into the suprasellar region. Diabetes insipidus was the initial clinical manifestation of lung cancer in this patient. A metastasis to the pituitary should be suspected if …