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PTSD

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Full-Text Articles in Psychological Phenomena and Processes

Anhedonia Underlies The Association Between Childhood Unpredictability And Adult Ptsd Symptoms: Evidence From Three Independent Longitudinal Cohorts, Christopher Hunt, Laura M. Glynn, Elysia Poggi Davis, Tallie Z. Baram, Caroline M. Nievergelt, Giovanni Castillo, Christian Cortes, Christine Y. Chang, Dewleen Baker, Victoria B. Risbrough Mar 2026

Anhedonia Underlies The Association Between Childhood Unpredictability And Adult Ptsd Symptoms: Evidence From Three Independent Longitudinal Cohorts, Christopher Hunt, Laura M. Glynn, Elysia Poggi Davis, Tallie Z. Baram, Caroline M. Nievergelt, Giovanni Castillo, Christian Cortes, Christine Y. Chang, Dewleen Baker, Victoria B. Risbrough

Psychology Faculty Articles and Research

Background

Unpredictability in the child’s environment has recently emerged as a significant and unique form of early life adversity (ELA). Cross-sectional studies have linked childhood unpredictability with increased post-traumatic stress disorder (PTSD) symptoms in adults; however, no prospective studies have tested the link between childhood unpredictability and PTSD risk in later life, nor what processes, such as increased anhedonia symptoms, might mediate such risk. Here, we leveraged three distinct prospective, longitudinal cohorts to test the hypothesis that unpredictability during childhood contributes to adult PTSD via worsening anhedonia symptoms.

Methods

Participants were male service members (n=314), adult females (n=170), and adolescents …


The Use Of Virtual Reality In Ptsd Research And Practice, Kenneth B. Abrams, Lindsay Okindo, Marta E. Bacon, Yiking Skylar Yu, Sofia Santamaria Germani, Malvika Malhotra, Nancy A. Cullen Jan 2026

The Use Of Virtual Reality In Ptsd Research And Practice, Kenneth B. Abrams, Lindsay Okindo, Marta E. Bacon, Yiking Skylar Yu, Sofia Santamaria Germani, Malvika Malhotra, Nancy A. Cullen

Psychology Faculty Work

In the aftermath of traumatic events such as combat, sexual violence, or a natural disaster, individuals may develop posttraumatic stress disorder (PTSD). Technological advancements in virtual reality (VR) over the past few decades have opened new avenues for improving the assessment, treatment, and understanding of PTSD. VR allows users to be immersed in interactive, computer-generated environments that simulate real-world scenarios, such as a warzone or assault location, that would be difficult or unsafe to reproduce using traditional methods. The present paper offers an overview of how VR technology has been employed in both clinical and research settings related to PTSD. …


Evaluating The Use Of Repetitive Transcranial Magnetic Stimulation In A Patient With Treatment Resistant Depression, Autism Spectrum Disorder, And Post-Traumatic Stress Disorder: A Case Report, Luke Fritsch Ba, Mba, Msiv, Oluwafunke O. Ogunremi Bs, Msiv, Alexandra R. Job Bs, Msiv, James Hellekson Md Jun 2025

Evaluating The Use Of Repetitive Transcranial Magnetic Stimulation In A Patient With Treatment Resistant Depression, Autism Spectrum Disorder, And Post-Traumatic Stress Disorder: A Case Report, Luke Fritsch Ba, Mba, Msiv, Oluwafunke O. Ogunremi Bs, Msiv, Alexandra R. Job Bs, Msiv, James Hellekson Md

Aesculapius Journal (Health Sciences & Medicine)

Despite a wide array of therapeutic modalities, many patients with Major Depressive Disorder (MDD) experience no significant improvement in symptoms with traditional treatment. Given the prevalence of Treatment Resistant Depression (TRD), other alternative therapeutic modalities for MDD are being researched. Repetitive Transcranial Magnetic Stimulation (rTMS) is one modality that continues to show successful therapeutic outcomes for those with TRD. The aim of this study is to highlight a case of rTMS being used on a patient with TRD, autism spectrum disorder (ASD), post-traumatic stress disorder (PTSD), and substance use.

Methods:

Our patient is a 53-year-old female who first presented to …


Neural Correlates Of Socially Rewarding Memories In Posttraumatic Stress Disorder, Kyle P. Blidy Oct 2024

Neural Correlates Of Socially Rewarding Memories In Posttraumatic Stress Disorder, Kyle P. Blidy

MUSC Theses and Dissertations

Significance. Memory disturbances for emotional content are central to PTSD, yet most research focuses on trauma memories. Recent evidence suggests that enhancing access to positive memories could improve mood, affect regulation, self-esteem, and integration of trauma memories. However, the neurocognitive mechanisms underlying positive memory encoding in PTSD are poorly understood. No study has examined memory for positive social items in PTSD, which is important because PTSD entails social withdrawal and reduced accessibility to positive memory. Additionally, positive memories embedded in a social context have enhanced subjective value and strengthening their accessibility may confer greater benefits to wellbeing compared to non-social …


Doxazosin Immediate Release As Alternative Treatment For Nightmares In Post-Traumatic Stress Disorder: A Case Report, Danyaal Khan, Christie Richardson, Martin Forsberg May 2024

Doxazosin Immediate Release As Alternative Treatment For Nightmares In Post-Traumatic Stress Disorder: A Case Report, Danyaal Khan, Christie Richardson, Martin Forsberg

Rowan-Virtua Research Day

Nightmares and flashbacks are common debilitating symptoms of post-traumatic stress disorder (PTSD) that can disrupt daily functioning in patients. Prazosin, an alpha-1 adrenergic antagonist, has been commonly used off-label for the treatment of PTSD intrusion symptoms, although its short half-life is limiting. Doxazosin, another alpha-1 antagonist, is starting to be investigated in the treatment of PTSD-related nightmares due to its smaller side effect profile and longer half-life. In our case report, we present a case of a patient with PTSD-related nightmares who was successfully treated with doxazosin following relapse of symptoms after discontinuation of prazosin. The success of doxazosin immediate …


Neurobiology Of Ptsd In Adults And Children: The Impact Of Stress-Induced Brain Abnormalities Across The Lifespan, Catherine Clover Jan 2023

Neurobiology Of Ptsd In Adults And Children: The Impact Of Stress-Induced Brain Abnormalities Across The Lifespan, Catherine Clover

Undergraduate Honors Theses

In the scholarly community, there is disagreement about the effects of PTSD or chronic stress on the brain of adults and children. Though PTSD or chronic stress are known to negatively affect neurobiological structures, specifically due to prolonged glucocorticoid excess, volumetric discrepancies between traumatized and control groups are not unanimously confirmed. This review sought to address the common understandings in academia of the effects of PTSD on the brains of adults and children. Literature on this topic indicated that, in adults, the hippocampus, cingulate gyrus, and prefrontal cortex bilaterally appeared to decrease in gray matter volume and the corpus callosum …


Exploring Attentional And Emotional Biases As A Function Of Trauma And Dissociation Symptomology, Claudia Clinchard Mar 2021

Exploring Attentional And Emotional Biases As A Function Of Trauma And Dissociation Symptomology, Claudia Clinchard

Department of Psychology: Dissertations, Theses, and Student Research

There is evidence that threatening facial expressions (e.g., angry faces) direct attention toward the target, and that for facial expressions that are less threatening but still convey negative valence (e.g., fear faces) direct attention outward and to one’s environment, therefore causing a shift in memory performance and attentional bias depending on the level of threat in emotional facial expressions presented. Extant literature provides evidence for attentional biases both towards and away from threat in those with posttraumatic stress disorder (PTSD) symptomology. The current study aimed to replicate the previous findings of the effects stimulus and emotion have on memory performance …


A Conceptual Proposal For The Epigenetically Causal Relationship Between Parental Ptsd And Inflammatory Disease In Post Hoc Offspring., Emma Griffith Jan 2021

A Conceptual Proposal For The Epigenetically Causal Relationship Between Parental Ptsd And Inflammatory Disease In Post Hoc Offspring., Emma Griffith

Williams Honors College, Honors Research Projects

Could a combat veteran's horrific experiences in early-2000s Afghanistan have a direct, biological impact his now-adult daughter's risk of a heart attack later in her life? This concept would have been unapologetically mocked a mere twenty years ago, and it has only been in the past decade that the new field of epigenetics has revealed a distinct possibility for this event to actually take place—for parents' experiences to profoundly influence the biology of their children. The major objective of this research project is to argue for the legitimacy of this theoretical phenomenon by discussing the latest data regarding PTSD's interaction …


Does Ethnic Identity, In-Group Preference, And Acculturation Protect Latinas With A History Of Interpersonal Trauma From Developing Symptoms Of Ptsd?, Evelyn M. Ramirez Sep 2019

Does Ethnic Identity, In-Group Preference, And Acculturation Protect Latinas With A History Of Interpersonal Trauma From Developing Symptoms Of Ptsd?, Evelyn M. Ramirez

Dissertations, Theses, and Capstone Projects

Previous research suggests ethnic identity, a sense of belonging to a particular cultural group, may be protective against symptoms of post-traumatic stress disorder (PTSD). However, the role of ethnic identity, in-group preference (i.e., an individual’s preference for interactions with members of their own ethnic group) and acculturation (i.e., the level of comfort with the mainstream culture) have not been investigated as protective factors for Latinas with a history of interpersonal and sexual trauma. In this study, ethnic identity, in-group preference and acculturation were assessed via self-report on the Scale of Ethnic Experience in two samples of undergraduate Latina and non-Latina …


Evaluation Of A New Trauma-Related Drinking To Cope Measure: Latent Structure And Heritability, Sage E. Hawn, Steven H. Aggen, Danielle Dick, Ananda B. Amstadter Phd Jan 2019

Evaluation Of A New Trauma-Related Drinking To Cope Measure: Latent Structure And Heritability, Sage E. Hawn, Steven H. Aggen, Danielle Dick, Ananda B. Amstadter Phd

Graduate Research Posters

Posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) commonly co-occur, share latent genetic risk, and are associated with many negative public health outcomes. Via a self-medication framework, trauma-related drinking to cope (TRD), an unexplored phenotype to date, may help explain why these two disorders co-occur, thus serving as an essential target for treatment and prevention efforts. This study sought to create a novel measure of TRD and to investigate its indirect influences on the association between PTSD and AUD, as well as its potential shared molecular genetic risk with PTSD in a genetically-informative study of college students. A sample …


Suicidal Ideation In Patients Hospitalized For Emergency Medical Treatment Related To Physical Trauma: Effects Of Posttraumatic Stress And Depression, Erin E. Carney Apr 2016

Suicidal Ideation In Patients Hospitalized For Emergency Medical Treatment Related To Physical Trauma: Effects Of Posttraumatic Stress And Depression, Erin E. Carney

Masters Theses & Specialist Projects

Survivors of physical trauma may be at increased risk for developing suicidal ideation and behavior both during and after their inpatient hospitalization for medical treatment of wounds. It remains to be understood why a population hospitalized for nonpsychiatric reasons may ultimately develop a desire to take their own life. The current study sought to answer this question by hypothesizing that symptoms of posttraumatic stress (PTS) and depression during the recovery period individually mediated the relationship between physical pain and suicidal ideation. Researchers assessed these relationships in 246 patients who were receiving emergency medical treatment for wounds associated with a physically …


2nd Place Contest Entry: Treatment Of Post-Traumatic Stress Disorder In A Veteran Population: Efficacy Of Complementary And Alternative Medicine Therapies, Brooke D. Snelgrove Apr 2015

2nd Place Contest Entry: Treatment Of Post-Traumatic Stress Disorder In A Veteran Population: Efficacy Of Complementary And Alternative Medicine Therapies, Brooke D. Snelgrove

Kevin and Tam Ross Undergraduate Research Prize

This is Brooke Snelgrove's submission for the 2014-2015 Kevin and Tam Ross Undergraduate Research Prize, which won second place. She wrote about the treatment of post-traumatic stress disorder (PTSD) among veterans with Complementary and Alternative Medicine therapies. You can read the final essay that came out of her research here.


Hiroshima And Mass Trauma Today: Treating Post-Traumatic Stress Disorder In Individuals And Communities, Ashley Martinez Jan 2015

Hiroshima And Mass Trauma Today: Treating Post-Traumatic Stress Disorder In Individuals And Communities, Ashley Martinez

International ResearchScape Journal

At 8:15 am on August 6th, 1945, the world and the way in which we fight wars changed forever. Immediately following the drop of the Little Boy atomic bomb, the city of Hiroshima was decimated, leaving the surviving citizens to deal with poverty, starvation, loss of loved ones, and utter destruction of their lives. After the bombing, survivors were left with burns, radiation poisoning, and physical scars. Unknown to the survivors of the atomic bombings, or Hibakusha, were the ensuing psychological and emotional damages. In 2014, we know more about traumatic experiences than in 1945. Studies from …


Inhibitory Control Deficits And Post-Traumatic Stress Disorder: Evidence From Eye Blink Rate, Mikael Rubin Jan 2014

Inhibitory Control Deficits And Post-Traumatic Stress Disorder: Evidence From Eye Blink Rate, Mikael Rubin

Dissertations and Theses

No abstract provided.


Rape Survivors: The Effects Of Post-Traumatic Stress And Locus Of Control On The Hoping Process, David Lester Rhoads May 1996

Rape Survivors: The Effects Of Post-Traumatic Stress And Locus Of Control On The Hoping Process, David Lester Rhoads

Graduate Theses

The current study examined the relationship between hope. Post Traumatic Stress Disorder, and locus of control in a sample, of 18 rape survivors and 18 non-raped females over 18 years of age. Instruments utilized were Herth Hope Scale, Structured Interview for Post Traumatic Stress Disorder, Impact of Events, and Locus of Control Scales. It was hypothesized that rape survivors would exhibit a lower level of hope, higher levels of Post Traumatic Stress Disorder, and an external locus of control. Independent t-tests revealed that rape trauma impacts Post Traumatic Stress Disorder. Independent t-tests were inconclusive among the hope, impact of events, …