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Full-Text Articles in Psychiatry and Psychology

History Of The South Dakota Human Services Center 1879-2019: Trials, Trends, And Tragedies To Transformation, Kate L. Katterhagen Apr 2020

History Of The South Dakota Human Services Center 1879-2019: Trials, Trends, And Tragedies To Transformation, Kate L. Katterhagen

Honors Thesis

The history of the South Dakota Human Services Center (HSC), located in Yankton, SD, spans 140 years, from the Dakota Territory days beginning in 1879 to the present. The trials, trends, and tragedies promoting transformation of the state psychiatric hospital are the focus of this thesis, with an emphasis on significant events that shaped the facility. This research examines the challenges and changes in public administration, treatment methods, and psychiatric medical practices. My research was accomplished through identification, retrieval, and review of archived materials, reports, published newspaper articles, and personal accounts. Societal, political, legal, medical, and historical perspectives frame my …


The Relationship Between Social Functioning And Anxiety Symptoms In Preschoolers With Autism, Kaylee L. Cox Apr 2020

The Relationship Between Social Functioning And Anxiety Symptoms In Preschoolers With Autism, Kaylee L. Cox

Senior Theses

Autism spectrum disorder (ASD) is characterized by impairments in social functioning. Furthermore, children with ASD have been found to have high rates of comorbid anxiety. Understanding the relationship between ASD and comorbid anxiety is essential in raising awareness of anxiety symptomology in children with ASD in hopes of better informing treatment and support. The present study examines the relationship between social functioning and general anxiety in children with ASD compared to typically developing (TD) children. The first objective of this study was to examine group differences in social impairments and anxiety symptoms between children diagnosed with ASD and TD children. …


Recognizing The Need For Mental Health Reform In The Texas Department Of Criminal Justice, Kara Mchorse Apr 2020

Recognizing The Need For Mental Health Reform In The Texas Department Of Criminal Justice, Kara Mchorse

St. Mary's Law Journal

The ways in which mental health care and the criminal justice system interact are in desperate need of reform in Texas. The rate of mental illness in Texas is higher than the current state of mental health care can provide for. While state hospitals were once the primary care facilities of those with mental illness, the Texas Department of Criminal Justice (TDCJ) has taken on that role in the last few decades; and when the criminal justice system becomes entangled with mental health care, it often leads to “unmitigated disaster.” If Texas continues to allow the TDCJ to act as …


An Investigation Of Word Learning In The Presence Of Gaze: Evidence From School-Age Children With Typical Development Or Autism Spectrum Disorder, Janet Y. Bang, Aparna S. Nadig Feb 2020

An Investigation Of Word Learning In The Presence Of Gaze: Evidence From School-Age Children With Typical Development Or Autism Spectrum Disorder, Janet Y. Bang, Aparna S. Nadig

Faculty Research, Scholarly, and Creative Activity

Little is understood about how children attend to and learn from gaze when learning new words, and whether gaze confers any benefits beyond word mapping. We examine whether 6- to 11-year-old typically-developing children (n = 43) and children with Autism Spectrum Disorder (n = 25) attend to and learn with gaze differently from another directional cue, an arrow cue. An eye-tracker recorded children’s attention to videos while they were taught novel words with a gaze cue or an arrow cue. Videos included objects when they were static or when they were manipulated to demonstrate the object’s function. Word learning was …


Discrimination, Coping, And Depression Among Black Men Who Have Sex With Men, Andre L. Brown, Jordan Sang, Leigh Bukowski, Steven Meanley, Byron D. Brooks, Cristian Chandler Feb 2020

Discrimination, Coping, And Depression Among Black Men Who Have Sex With Men, Andre L. Brown, Jordan Sang, Leigh Bukowski, Steven Meanley, Byron D. Brooks, Cristian Chandler

Journal of Health Disparities Research and Practice

Black men who have sex with men (BMSM) have elevated risk for depression compared to the general population. BMSM’s capacity to cope with these experiences is not well understood. Increased understanding of how multiple forms of discrimination contribute to depression and how BMSM cope with discrimination can better inform interventions. Data come from 3,510 BMSM who attended Black Pride events in six U.S. cities from 2015-2017. Participants completed a health survey that ascertained their psychosocial health and resiliency profiles. Using multivariable logistic regression models, we tested the associations between type-specific discrimination (race, sexuality, HIV status) and depression. We then conducted …


Postpartum Depression! One Iv And I Am Back To Happy!, Gabrielle Dubruille Jan 2020

Postpartum Depression! One Iv And I Am Back To Happy!, Gabrielle Dubruille

All Publications

No abstract provided.


The Missing Moral Dimension: Perceptions Of Transgressions And The Moderating Role Of Moral Foundations On Psychological Distress, Hannah Reas Jan 2020

The Missing Moral Dimension: Perceptions Of Transgressions And The Moderating Role Of Moral Foundations On Psychological Distress, Hannah Reas

Clinical Psychology Dissertations

Anxiety and depression can be represented on a dimensional spectrum of negative affect, broadly termed psychological distress. Research has identified several factors that maintain negative emotion, but have neglected the possibility that individuals’ interpretations of moral issues in the larger macro-system affects their level of distress. Thus, the current study investigated the role of perceptions of moral transgressions, or cognitive interpretations of stimuli (“transgressions”) that violate beliefs about right and wrong, as a predictor of psychological distress. Furthermore, this study tested how perceptions of moral transgressions vary as a function of individuals’ own moral intuitions, or moral foundations. Participants ( …


Attitudes Towards Mental Illness In American Evangelical Communities, Supernaturalism, And Stigmatization, Nahanni Freeman, Isaac Baldwin Jan 2020

Attitudes Towards Mental Illness In American Evangelical Communities, Supernaturalism, And Stigmatization, Nahanni Freeman, Isaac Baldwin

Faculty Publications - Psychology Department

Social-cognitive variables and religious attributions regarding mental illness were examined with a homogeneous sample of 180 American Evangelical Christians, using a novel tool and the Mental Health Knowledge Scale (MAKS). In the first trial, participants were randomly assigned to one of two Bible verse priming conditions, which made salient willpower, faith and anxiety-reduction or the suffering Christ. Priming effects revealed that those exposed to the willpower-faith admonishment condition showed lower stigma on the MAKS and stronger condition recognition scores. Participants who endorsed unilateral religious causes and solutions to mental illness also presented with less knowledge about mental health disorders and …


Impact In Hospitalization Of Mental Health Patients With Dual Diagnosis As It Pertains To Medicaid And Treatment With Mat Services, Amanda Akmentins Jan 2020

Impact In Hospitalization Of Mental Health Patients With Dual Diagnosis As It Pertains To Medicaid And Treatment With Mat Services, Amanda Akmentins

Theses, Dissertations and Capstones

Introduction

About 17.5 million Americans over the age of 18 have been diagnosed with a mental illness, and about 4 million of those individuals have also been diagnosed with a substance use disorder. Medicaid requirements made to those receiving Medication Assisted Treatment (MAT) services provide access to quality care to reduce re-hospitalization by focusing on behavioral changes and accountability. The purpose of this research was to analyze the impact of hospitalization rates to determine unmet needs and barriers to receiving treatment for those that have a dual diagnosis.

Methodology

The methodology was a literature review. Thirty-two sources were referenced for …


Creating A Place For Monstrosity: The Forced Liminality And Limited Mobility Of Codified Monstrosity In Leigh Bardugo's King Of Scars, Kaylee Brooke Lambert Jan 2020

Creating A Place For Monstrosity: The Forced Liminality And Limited Mobility Of Codified Monstrosity In Leigh Bardugo's King Of Scars, Kaylee Brooke Lambert

Online Theses and Dissertations

The Young Adult Library Services Association (YALSA) outlines the purpose of young adult (YA) literature as addressing the unique needs of adolescents, which are “distinguished by unique needs that are – at minimum — physical, intellectual, emotional, and societal in nature” (Cart “Value” para. 8). This unique period in life is liminal, a time between childhood and adulthood. Adolescents search for meaning in the world around them, with literature as one avenue for self-discovery and affirmation. Mental health is one area teenagers seek answers, and YA literature has attempted to provide spaces to navigate those questions in popular contemporary works …


Psilocybin-Assisted Psychotherapy: Treating Depression And Anxiety With Mushrooms, Sofia Beck Jan 2020

Psilocybin-Assisted Psychotherapy: Treating Depression And Anxiety With Mushrooms, Sofia Beck

Physician Assistant Studies | Student Authored Articles

Depression and anxiety are debilitating mental health conditions that affect a large portion of the United States. Current pharmacological treatments for these disorders require daily administration, are associated with a number of side effects, and can be ineffective for some. Emerging evidence in novel treatment options may necessitate a shift toward how we treat these psychiatric disorders.

Studies involving the psychedelic serotonin agonist, psilocybin, are currently experiencing a resurgence as an alternative for patients who are unresponsive to traditional treatments. Clinical trials using psilocybin in combination with psychotherapy have demonstrated sustained reductions in depression and/or anxiety symptoms. When used in …


A Five-Sample Confirmatory Factor Analytic Study Of Burnout-Depression Overlap, Renzo Bianchi, Irvin Sam Schonfeld, Jay Verkuilen Jan 2020

A Five-Sample Confirmatory Factor Analytic Study Of Burnout-Depression Overlap, Renzo Bianchi, Irvin Sam Schonfeld, Jay Verkuilen

Publications and Research

Objective: It has been asserted that burnout—a condition ascribed to unresolvable job stress—should not be mistaken for a depressive syndrome. In this confirmatory factor analytic study, the validity of this assertion was examined.

Methods: Five samples of employed individuals, recruited in Switzerland and France, were mobilized for this study (N = 3,113). Burnout symptoms were assessed with the Shirom–Melamed Burnout Measure, the Maslach Burnout Inventory (MBI)—General Survey, and the MBI for Educators. Depressive symptoms were measured with the PHQ‐9.

Results: In all five samples, the latent factors pertaining to burnout’s components correlated on average more highly with the latent Depression …


Evaluating Interpersonal Problems In Anorexia Nervosa Through The Lens Of Polyvagal Theory, Marika Morelan Jan 2020

Evaluating Interpersonal Problems In Anorexia Nervosa Through The Lens Of Polyvagal Theory, Marika Morelan

CMC Senior Theses

Eating disorders are an increasingly prevalent issue, especially among young women. While they aren’t a new phenomenon, they are historically under-researched, and remain widely misunderstood. Without understanding the causes underlying these disorders or the mechanisms working to maintain them, treating them successfully has proved to be incredibly difficult. This is especially the case with Anorexia Nervosa. Out of the six eating disorders in the DSM-5, it has the lowest treatment success rate and an alarmingly high relapse rate. Treating the disorder through weight restoration and the extinction of compensatory behaviors alone does not fully resolve the disordered pathology; interpersonal problems …


Schizophrenia Spectrum Disorders: Linking Motor And Process Skills, Sensory Patterns, And Psychiatric Symptoms, Lola Halperin, Janet Falk-Kessler Jan 2020

Schizophrenia Spectrum Disorders: Linking Motor And Process Skills, Sensory Patterns, And Psychiatric Symptoms, Lola Halperin, Janet Falk-Kessler

Occupational Therapy Faculty Publications

Background: Consistent evidence suggests sensory abnormalities and skill deficits in people with Schizophrenia Spectrum Disorder (SSD). Further exploration of their sensory patterns and performance skills is warranted to promote community participation among these individuals.

Method: This study examined sensory patterns and motor and process skills in relationship to psychiatric symptoms in adult patients with SSD. Participants were evaluated using the Adolescent/Adult Sensory Profile, the Assessment of Motor and Process Skills, and the Brief Psychiatric Rating Scale.

Results: Of the 18 participants, the majority showed sensory differences, deficits in motor and process skills, and the presence of moderate to severe symptoms. …


Fight, Flight, Or Freezing? Investigating The Immobility Response In Military Veterans, Paige Elizabeth King Jan 2020

Fight, Flight, Or Freezing? Investigating The Immobility Response In Military Veterans, Paige Elizabeth King

UNF Graduate Theses and Dissertations

When the body is faced with threat to life or limb, the autonomic nervous system works to overcome the danger – by either fight, flight, or freezing. While immobility may not appear to be the most logical solution, theories exist that it allows for judgement of the situation and preparation for action. This study investigated the stress response that military veterans, with or without post-traumatic stress disorder (PTSD), demonstrate when shown unpleasant images. Researchers wanted to determine the extent to which veterans would show freezing or immobile responses when under an unpleasant image condition. It was hypothesized that veterans who …


The Impact Of Bone Marrow Transplantion On Patients With Psychiatric Diagnoses: Medication Adherence Assessment, Brittany Galop Jan 2020

The Impact Of Bone Marrow Transplantion On Patients With Psychiatric Diagnoses: Medication Adherence Assessment, Brittany Galop

Theses and Dissertations--Pharmacy

Objectives: We investigated whether there is a measurable difference in medication utilization for psychiatric conditions before and after bone marrow transplantation (BMT). Previous studies have identified a potential association between psychiatric conditions and immune function. We hypothesized that medication utilization for psychiatric diagnoses would be impacted by BMT.

Methods: This study was a retrospective, quasi-experimental cohort design. De-identified data was compiled from the Truven database for patients ranging from January 2009 through December 2016. Two measurements of medication utilization, proportion of days covered (PDC) and medication possession ratio (MPR) were calculated for each included Medispan-defined class of medications before analyzing …


The Efficacy Of Yoga As An Adjunctive Therapy To Standard Multidisciplinary Care In The Treatment Of Female Patients Presenting With Cognitive Eating Disorder Symptoms, Cassidy Nagle Jan 2020

The Efficacy Of Yoga As An Adjunctive Therapy To Standard Multidisciplinary Care In The Treatment Of Female Patients Presenting With Cognitive Eating Disorder Symptoms, Cassidy Nagle

Capstone Showcase

Introduction: Current treatment of patients exhibiting cognitive eating disorder symptoms is standard multidisciplinary care (SMDC) involving behavioral therapy, medical management and dietetics. Because these symptoms often persist or relapse despite treatment, research has begun to explore adjunctive therapies like yoga for this population. This review will explore seven studies in order to analyze the effect of yoga (I) on cognitive eating disorder symptoms (O) in teenage and adult females (P) when added to SMDC compared to symptom reduction with SMDC alone (C).

Methods: A literature search was conducted in PubMed, Academic Search Ultimate and Google Scholar starting November 2018. Seven …


Association Of Genetic Risks With Autism Spectrum Disorder And Early Neurodevelopmental Delays Among Children Without Intellectual Disability, Nagahide Takahashi, Taeko Harada, Tomoko Nishimura, Akemi Okamura, Damee Choi, Toshiki Iwabuchi, Hitoshi Kuwabara, Shu Takagai, Yoko Nomura, Nori Takei, Kenji J. Tsuchiya Jan 2020

Association Of Genetic Risks With Autism Spectrum Disorder And Early Neurodevelopmental Delays Among Children Without Intellectual Disability, Nagahide Takahashi, Taeko Harada, Tomoko Nishimura, Akemi Okamura, Damee Choi, Toshiki Iwabuchi, Hitoshi Kuwabara, Shu Takagai, Yoko Nomura, Nori Takei, Kenji J. Tsuchiya

Publications and Research

IMPORTANCE Autism spectrum disorder (ASD) is highly heritable, and modest contributions of common genetic variants to ASD have been reported. However, the association of genetic risks derived from common risk variants with ASD traits in children from the general population is not clear, and the association of these genetic risks with neurodevelopment in infants has not been well understood.

OBJECTIVE To test whether a polygenic risk score (PRS) for ASD is associated with neurodevelopmental progress at age 18 months and ASD traits at age 6 years among children from the general population.

DESIGN, SETTING, AND PARTICIPANTS In this cohort study, …


An Examination Of Social Connectedness On Ptsd And Freezing In A Student Military Population, Jessica Marie Ledwith Jan 2020

An Examination Of Social Connectedness On Ptsd And Freezing In A Student Military Population, Jessica Marie Ledwith

UNF Graduate Theses and Dissertations

This study investigates the impact of social connectedness (SC) and post-traumatic stress disorder (PTSD) in a military college population, and their relation to physiological measures such as body sway, heart rate (HR), and heat rate variability (HRV). According to previous research, people with PTSD are more likely to exhibit a freezing response to affective images. In the present study, we explore the potential freezing response for military personnel at the levels of PTSD symptom groups and social connectedness. We also investigate the possible buffering effect social connectedness has on the outcome of PTSD and freezing. There was a total of …


Mental Health Service Use In The Kingdom Of Saudi Arabia, Abdulaziz S. Alangari Jan 2020

Mental Health Service Use In The Kingdom Of Saudi Arabia, Abdulaziz S. Alangari

Graduate Theses, Dissertations, and Problem Reports (ETD)

Objectives: The goal of this project was to increase knowledge concerning the current prevalence, needs and barriers to mental health service use in the Kingdom of Saudi Arabia (KSA). It’s purpose was to gather data that would help to inform future policy decisions aimed at optimizing the use and availability of these services in the KSA. There were three specific aims: 1) Examine the barriers to initiation and continuation of mental health treatment in people with a disorder diagnosed during the previous 12-months. 2) Explore the prevalence and predictors of mental health treatment dropout. 3) Examine the prevalence and patterns …


Mechanisms Of Value-Biased Prioritization In Fast Sensorimotor Decision Making, Kivilcim Afacan-Seref Jan 2020

Mechanisms Of Value-Biased Prioritization In Fast Sensorimotor Decision Making, Kivilcim Afacan-Seref

Dissertations and Theses

In dynamic environments, split-second sensorimotor decisions must be prioritized according to potential payoffs to maximize overall rewards. The impact of relative value on deliberative perceptual judgments has been examined extensively, but relatively little is known about value-biasing mechanisms in the common situation where physical evidence is strong but the time to act is severely limited. This research examines the behavioral and electrophysiological indices of how value biases split-second perceptual decisions and the possible mechanisms underlying the process. In prominent decision models, a noisy but statistically stationary representation of sensory evidence is integrated over time to an action-triggering bound, and value-biases …


A Natural Remedy: Nbccpt Approach In School For Adhd Diagnosed, Kiran Patel Jan 2020

A Natural Remedy: Nbccpt Approach In School For Adhd Diagnosed, Kiran Patel

Capstone Showcase

Nature-based child centered play therapy (NBCCPT) is a non-directive approach that can be practiced by the counselor in a natural environment consisting of natural tools. The approach allows a child to lead a therapy session without the counselor’s input. Such an approach can be beneficial for children with Attention deficit hyperactivity disorder (ADHD), especially in a school setting. Therapy in school can aid families that cannot afford outpatient therapy as well as allow counselors to track the child’s therapy progress. In school, counselors can utilize an outdoor garden to conduct NBCCPT with the help of five stages, planning, preparing, planting, …


Non-Pharmacological Interventions For Alcohol, Marijuana, And Opioid Use During Pregnancy: A Systematic Review, Hannah Safranek, Madeline Frausto, Amy King, Stoneking Madison Jan 2020

Non-Pharmacological Interventions For Alcohol, Marijuana, And Opioid Use During Pregnancy: A Systematic Review, Hannah Safranek, Madeline Frausto, Amy King, Stoneking Madison

Williams Honors College, Honors Research Projects

The purpose of this review is to analyze evidence on prevalence of opioid, alcohol and marijuana use during pregnancy and answer the PICOT question: In pregnant women addicted to or using marijuana, opioids, and alcohol, how do non-pharmacological interventions, compared to standard care of pharmacological interventions alone, affect health outcomes in mothers and neonates between birth to hospital discharge? Diagnosis of substance use disorder is increasing and with it comes increased risk of complications to mother and neonate including neonatal abstinence syndrome (NAS), fetal alcohol syndrome (FAS) and other negative neonatal and maternal outcomes. Evidence was identified on the online …


College Students’ Perceptions Of Popular Diets And Orthorexia Nervosa, Madison W. Weinstock Jan 2020

College Students’ Perceptions Of Popular Diets And Orthorexia Nervosa, Madison W. Weinstock

Theses and Dissertations

Data suggest that individuals’ purported dietary patterns influence others’ perceptions of them. However, few studies have investigated how adherence to specific popular diets might influence these perceptions. This study investigated female undergraduates’ (n = 463) perceptions of vignette characters described as adhering to specific dietary practices perceptions of a vignette character in a sample of 463 female undergraduates. Characters described as adhering to a Clean Eating diet were viewed most positively, followed by individuals on the Ketogenic diet or nondieters. Characters following an Intermittent Fasting diet, and those with Orthorexia Nervosa were viewed most negatively. These findings support the …


Impact Of A Multimodal Exercise Program On Tibial Bone Health In Adolescents With Development Coordination Disorder: An Examination Of Feasibility And Potential Efficacy, Jocelyn L. Tan, Aris Siafarikas, Timo Rantalainen, Nicolas H. Hart, Fleur Mcintyre, Beth Hands, Paola Chivers Jan 2020

Impact Of A Multimodal Exercise Program On Tibial Bone Health In Adolescents With Development Coordination Disorder: An Examination Of Feasibility And Potential Efficacy, Jocelyn L. Tan, Aris Siafarikas, Timo Rantalainen, Nicolas H. Hart, Fleur Mcintyre, Beth Hands, Paola Chivers

Research outputs 2014 to 2021

© 2020, International Society of Musculoskeletal and Neuronal Interactions. All rights reserved. Objectives: Developmental coordination disorder (DCD) compromises bone health purportedly due to lower levels of physical activity. The potential of an exercise intervention to improve bone health parameters in adolescents with DCD has not previously been studied. This study thus aimed to determine the impact of a multimodal exercise intervention on bone health in this population at-risk of secondary osteoporosis. Methods: Twenty-eight adolescents (17 male, 11 female) aged between 12-17 years (Mage =14.1) with DCD participated in a twice weekly, 13-week generalised multimodal exercise intervention. Peripheral quantitative computed tomography …


Military Veteran Students Transition To Academic Life With Ptsd, Trauma, And Potential For Freezing Response., Alicia Marie Erchul Jan 2020

Military Veteran Students Transition To Academic Life With Ptsd, Trauma, And Potential For Freezing Response., Alicia Marie Erchul

UNF Graduate Theses and Dissertations

The current study is the first known research to investigate the association of the freezing response with PTSD and traumatic stress in the military veteran student population. Current understanding of the freezing response are primarily based in comparative psychology, with some studies extending to human participants (Azevedo et al., 2005; Facchinetti et al., 2006; Hagenaars et al., 2012; Volchan et al., 2017). Models generally agree that the freezing response consists of reduced body sway with decreased heart rate (Porges, 2003, 2007; Hagenaars et al., 2014).

Thirty-eight military veteran students (n=38; 18 female; 20 male) with ages ranged from 19 to …


Effects Of (R,S)-Ketamine And (2r,6r)-Hydroxynorketamine: A Preclinical Study, Remington Rice Jan 2020

Effects Of (R,S)-Ketamine And (2r,6r)-Hydroxynorketamine: A Preclinical Study, Remington Rice

Theses and Dissertations

In 2017, 7.1% of US adults were diagnosed with depression, and 50% of patients received medication to treat their depression. Depression can cause severe interruptions in an individual's cognitive functioning and behaviors like sleeping, eating, working, and socializing. Unfortunately, approximately 40% of patients do not respond to treatment with monoaminergic medications (e.g. Prozac) and therapeutic effects may be delayed 2-8 weeks. Due to these therapeutic shortcomings, faster acting and more efficacious treatments are needed. Recent preclinical findings indicate potential for glutamatergic drugs like (R,S)-ketamine and (2R,6R) hydroxynorketamine to produce more rapid and longer-acting therapeutic effects. The antidepressant effectiveness of (R,S)-ketamine …


An Exploratory Study Of How Millennials Approach And Communicate Mental Health In The Workplace, Johanna I. Seitenbach Dec 2019

An Exploratory Study Of How Millennials Approach And Communicate Mental Health In The Workplace, Johanna I. Seitenbach

Student Theses and Dissertations

Depression is the leading cause of disability worldwide, affecting more than 300 million people. As more millennials take on leadership positions, it is important to understand how companies are currently addressing mental health in the workplace and compare this to how millennials approach the subject. The quantitative analysis completed through this study helped to determine what a mentally healthy workplace looks and feels like for millennials. Companies are increasingly investing in mental health initiatives for several reasons: to increase brand recognition, to improve company culture, to mitigate potential lawsuits, and to increase employee engagement and retention. This survey assessed how …


Memantine: Can It Be Used To Treat Children With Autism Spectrum Disorder?, Austin Brown, Katherine Liu, Pul Lee, Rachel Muhlenkamp, Manoranjan D'Souza Dec 2019

Memantine: Can It Be Used To Treat Children With Autism Spectrum Disorder?, Austin Brown, Katherine Liu, Pul Lee, Rachel Muhlenkamp, Manoranjan D'Souza

Pharmacy and Wellness Review

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairment in social, behavior and communicative skills. The current therapy for ASD only targets the associated symptoms such as aggression, self-harming acts or temper tantrums but not the core symptoms of social dysfunction. The pathology of ASD is not fully understood. Interestingly, imaging studies in ASD patients have reported abnormal high levels of glutamate in certain brain regions that play an important role in social interaction and communication. Thus, it has been hypothesized that medications attenuating glutamate transmission may be used as treatment for some of the core symptoms of …


The Use Of Propranolol In The Treatment Of Posttraumatic Stress Disorder, Tana M. Peterman, Alison L. Huet, Sarah E. Drake, Jamie L. Drees, Robert D. Raiff, B. Shane Martin Dec 2019

The Use Of Propranolol In The Treatment Of Posttraumatic Stress Disorder, Tana M. Peterman, Alison L. Huet, Sarah E. Drake, Jamie L. Drees, Robert D. Raiff, B. Shane Martin

Pharmacy and Wellness Review

This article examines the rising issue of post-traumatic stress disorder (PTSD) and possible treatment options. PTSD is a behavioral disorder resulting from memory formation and association with a traumatic event. A search of the published literature reveals several positive studies and case reports suggesting that propranolol, a beta adrenergic receptor antagonist, may be useful for both treatment and prevention of PTSD. Additionally, current studies are being completed in different population groups to determine the overall effectiveness and mechanism by which propranolol is able to provide relief from certain symptoms common to the disorder. This article discusses the medical evidence and …