Psychiatry and Psychology Commons^™

Ketamine Psychedelic Psychotherapy: Focus On Its Pharmacology, Phenomenology, And Clinical Applications, Eli Kolp, Harris L. Friedman, Evgeny Krupitsky, Karl Jansen, Mark Sylvester, M. Scott Young, Anna Kolp

Mental Health Law & Policy Faculty Publications

Meant to be an authoritative guide for psychiatrists and others interested in understanding and applying ketamine psychedelic psychotherapy (KPP), this paper focuses on its pharmacology, phenomenology, and clinical applications. Ketamine is a dissociative anesthetic widely used by physicians and veterinarians in the United States. In addition to its anesthetic and dissociative properties, ketamine also has a multitude of other psychological and pharmacological properties, which include analgesic, sedative, neuroprotective, anxiolytic, antidepressant, stimulant, euphoriant, and hallucinogenic effects. The literature on the clinical application of KPP is comprehensively reviewed, practical advice for using KPP is given, and the pharmacology and phenomenology of ketamine-induced …

Safe Haven Implementation Brief, Roger Casey, Paul Smits, M. Scott Young

Mental Health Law & Policy Faculty Publications

No abstract provided.

Diabetes Insipidus In Patient With Bodydysmorphic And Eating Disorder, Vasudev G. Magaji Md, Ms, Gretchen Perilli Md

Department of Medicine

No abstract provided.

Discovering Behavioral Intervention: A Parent’S Interactive Guide To Aba, Richard Fleming, Carol Curtin, Cheryl A. Gray, Charles D. Hamad

Current Issues in Emerging eLearning

Autism spectrum disorders (ASD) affect one in 110 children in the U.S. Parents of children with ASD need clear and accurate information to communicate with professionals as they seek appropriate services, including applied behavior analysis (ABA) based intervention. Behavioral professionals can assist parents in this endeavor by recommending resources, including online courses. This paper describes the development and evaluation of an online course on ABA for parents of children with ASD. Parents completing a summative field test (N=21) made significant gains in knowledge and reported high levels of satisfaction. Implications include the potential for enhanced parent-professional collaboration in treatment decision-making.

A New Brief Scale To Assess Suicidality: Scale For Impact Of Suicidality-Management, Assessment And Planning Of Care (Sis-Map- Brief Scanner), Amresh Srivastava, Megan Johnston, Miky Kaushal, Robbie Campbell, Charles Nelson

Data and Test Instruments

Purpose: In this study we examine merit of a short version (Brief Interview Screener (SIS-MAP-scn )of a previously developed and validated 108 item scale, known as ‘ Scale for Impact of Suicidality-Management, Assessment and Planning of Care ( SIS MAP), for rapid assessment in challenging clinical settings e.g. primary care and emergency room. Background: Generally suicide risk is assessed clinically and structured assessments optimize the direction for decision-making across various settings e.g. inpatient care, emergency rooms and crisis centers. We believe that measures with accurate and valid information should be based upon multifactorial risk-constituent domains, e.g. biological, social, psychological, environmental …

Relationship Between Sensory Sensitivities And Cognitive And Adaptive Abilities In Children With Autism Spectrum Disorders, Laura Pendergast

Honors Scholar Theses

Sensory sensitivities are widely reported among individuals with ASD. These sensory sensitivities can be classified as over-responsivity, under-responsivity, or seeking of sensory stimulation. Following recent changes in the diagnostic criteria, sensory sensitivities are considered a key feature of the behavioral phenotype of ASDs. Despite their significance, sensory sensitivities have been largely underestimated. Therefore, more research in this area may reveal important information about the influence of sensitivities on functioning, as well as the underlying causes of the symptoms. This study investigated a possible relationship between sensory sensitivities and cognitive and adaptive abilities in children with ASD. The sample included 29 …

Narco-Trauma: The Phenomenology Of The Mexican Drug War Among Binational Students At The Border, Kathleen A. O'Connor

Nursing Faculty Publications

In this article, I present research conducted among 242 university students living in the binational metropolitan area encompassing El Paso, Texas, and Ciudad Juárez, Mexico, that has been affected by drug violence. The particular focus is on narratives of social suffering and lived experience in the context of drug violence.

Impulsive Choice In Unmedicated And Medicated Children Diagnosed With Adhd: Examining The Variables Of Reward Type And Adhd Subtype, Nicole Henriksen

Dissertations

Developmentally inappropriate and impairing impulsive behaviors are often seen in attention-deficit/hyperactivity disorder (ADHD). One method for objectively assessing impulsivity is the Choice-Delay Task (C-DT) which presents repeated opportunities to choose between a smaller, sooner (SS) or larger, later (LL) reward. A preference for the SS reward that results in less total reward is considered impulsive. Many studies have found that participants diagnosed with ADHD choose the SS reward more than typical controls. However, less is known about the effects of different types of rewards, or the comparative performance of certain subgroups, such as children diagnosed with ADHD Predominantly Inattentive Type …

The Intersection Of Depression, Partner Violence And Poverty During The Perinatal Period, Catherine L. Kothari

Dissertations

Problem: Despite the wealth of research documenting the individual links between maternal depression, partner violence, and poverty, important gaps remain regarding their combined interactions, and their variation related to perinatal timing (pregnancy and postpartum). The current dissertation examined the interplay of these phenomena across perinatality.

Methods: This dissertation utilized secondary analysis of telephone survey data from a representative sample of women recruited during their postpartum hospital stay and interviewed four times over the subsequent 18 months. Linear regression was used for predictive modeling of fixed effects, and generalized estimating equation regression was used for multivariate analysis of temporal trends.

Findings: …

Swing Dancing Along The Spectrum: A Proposed Unique Adjunctive Treatment Approach For Individuals With Autism Spectrum Disorder, Alia Mulder-Rosi

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

Autism Spectrum Disorder (ASD) is a class of developmental disorders typically diagnosed during childhood. ASD is characterized by social deficits and repetitive behavioral patterns, which cause clinically significant impairment and are not better explained by intellectual disability (American Psychiatric Association, 2013). This doctoral paper proposes swing dancing as an adjunctive treatment option for high functioning adults with ASD. Swing dance is a category of social, partner dance initially set to swing style jazz music. This category most notably includes Lindy Hop, Charleston, Jitterbug and Balboa. Swing dance is an activity which grants social structure, is typically surrounded by an accepting …

Does Negative Affect Mediate The Relationship Between Daily Ptsd Symptoms And Daily Alcohol Involvement In Female Rape Victims? Evidence From 14 Days Of Interactive Voice Response Assessment, Amy Cohn, Brett T. Hagman, Kathleen A. Moore, Jessica Mitchell, Sarah Ehlke

Mental Health Law & Policy Faculty Publications

The negative reinforcement model of addiction posits that individuals may use alcohol to reduce negative affective (NA) distress. The current study investigated the mediating effect of daily NA on the relationship between daily PTSD symptoms and same-day and next-day alcohol involvement (consumption and desire to drink) in a sample of 54 non-treatment-seeking female rape victims who completed 14 days of interactive voice response assessment. The moderating effect of lifetime alcohol use disorder diagnosis (AUD) on daily relationships was also examined. Multilevel models suggested that NA mediated the relationship between PTSD and same-day, but not next-day alcohol involvement. NA was greater …

Tripartite Conflicts Of Interest And High Stakes Patent Extensions In The Dsm-5, Lisa Cosgrove, Sheldon Krimsky, Emily E. Wheeler, Jenesse Kaitz, Scott B. Greenspan, Nicole L. Dipentima

Counseling, School Psychology & Sport Faculty Publication Series

Background: The revision process for and recent publication of the DSM-5 initiated debates about the widening of diagnostic boundaries. The pharmaceutical industry had a major financial stake in the outcome of these debates. This study examines the three-part relationship among DSM panel members, principal investigators (PIs) of clinical trials for new DSM-5 diagnoses, and drug companies.

Methods: Financial conflicts of interest (FCOI) of DSM panel members responsible for some new diagnoses in the DSM-5 and PIs of clinical trials for related drug treatments were identified. Trials were found by searching ClinicalTrials.gov. Patent and revenue information about these drugs was found …

Is Hyperbaric Oxygen Therapy An Effective Treatment For Autism? A Review, Daniel Dunleavy, Bruce A. Thyer

Journal of Adolescent and Family Health

Objectives: We review outcome studies regarding the effectiveness of hyperbaric oxygen therapy (HBOT) for Autism Spectrum Disorders (ASD). Method: Studies were identified through electronic bibliographic databases and manual searches of article reference lists. Results: A total of 8 studies met eligibility criteria, consisting of three randomized controlled trials (RCTs), one quasi-experimental study involving a comparison group, two pre-experimental one-group pretest–posttest studies, and two single-system designs. Studies reviewed did not offer credible evidence to suggest that HBOT is an effective treatment for autism. Conclusion: It is premature to call HBOT an effective treatment for Autism and ASD. Individuals clinically treated with …

An Introduction To Drugs And The Neuroscience Of Behavior, Adam J. Prus

Books

This up-to-date text provides an introductory overview of the nervous system actions and behavioral effects of the major classes of psychoactive drugs, using pedagogy unique among pharmacology texts to make the topic approachable.

A Clustering Method To Identify Who Benefits Most From The Treatment Group In Clinical Trials, Beom S. Lee, Pranab K. Sen, Nan Park, Roger A. Boothroyd, Roger H. Peters, David A. Chiriboga

Mental Health Law & Policy Faculty Publications

In randomized controlled trials (RCTs), the most compelling need is to determine whether the treatment condition was more effective than control. However, it is generally recognized that not all participants in the treatment group of most clinical trials benefit equally. While subgroup analyses are often used to compare treatment effectiveness across pre-determined subgroups categorized by patient characteristics, methods to empirically identify naturally occurring clusters of persons who benefit most from the treatment group have rarely been implemented. This article provides a modeling framework to accomplish this important task. Utilizing information about individuals from the treatment group who had poor outcomes, …

The Role Of Positive Alcohol Expectancies In Underage Binge Drinking Among College Students, Nicole M Mcbride, Blake Barrett, Kathleen A. Moore, Lawrence Schonfeld

Mental Health Law & Policy Faculty Publications

Objective: This study explored associations between positive alcohol expectancies, and demographics, as well as academic status and binge drinking among underage college students. Participants: A sample of 1,553 underage college students at 3 public universities and 1 college in the Southeast who completed the Core Alcohol and Drug Survey in the Spring 2013 semester. Methods: A series of bivariate analyses and logistic regression models were used to examine associations between demographic and academic status variables as well as positive alcohol expectancies with self-reported binge drinking. Positive alcohol expectancies were examined in multivariable models via 2 factors derived from principal component …

Is Propranolol Administration Following A Traumatic Event Effective In Reducing Symptoms Of Post-Traumatic Stress Disorder?, Timothy J. Goulet

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not propranolol administration following a traumatic event is effective in reducing symptoms of post-traumatic stress disorder (PTSD).

STUDY DESIGN: Review of three English language randomized, double-blind, placebo-controlled clinical trials published in 2002, 2007, and 2010.

DATA SOURCES: Three randomized, double-blind, placebo-controlled clinical trials found using PubMed and Cochrane Library databases.

OUTCOMES MEASURED: The incidence of PTSD symptoms was measured in patients following traumatic events after the administration of propranolol. This was done using The Screening Tool for Early Predictors of PTSD, the Clinician …

Eating Disorders: The Hidden Hormonal Effect On Fertility, Esther Tessler-Karfunkel

The Science Journal of the Lander College of Arts and Sciences

Women who have a history of eating disorders, specifically anorexia nervosa, are more prone to suffer from infertility. There are several hormones which are the driving force in this system and are therefore responsible for this. Fortunately, there are treatments which can help women with a history of eating disorders to reproduce. Using information found on Pubmed and Touro College’s database, this paper will discuss why the body cannot reproduce when it is lacking proper nutrition, as well as the various dynamics in the human reproductive system which are compromised when the body is not properly nourished.

Firesetting Behavior And Psychiatric Disorders, Stephanie Stockburger, Hatim A. Omar

Pediatrics Faculty Publications

Firesetting behavior results in serious damage to lives and property every year. Firesetting has been linked to a number of comorbid psychiatric disorders including depression, substance abuse, conduct disorder, antisocial personality disorder, obsessive compulsive disorder, psychotic disorder, schizoid personality disorder, and schizophrenia. Psychiatric disorders differ by gender. In addition, juvenile firesetters have history of a separate set of psychiatric comorbidities. The strong correlation between psychiatric comorbidities and firesetting behavior illustrates the need for fire service and mental health collaboration.

Dopamine And Glutamate Dysfunction In A Rodent Model Of Attention-Deficit/Hyperactivity Disorder: Implications For Future Neuropharmacology, Erin M. Miller

Theses and Dissertations--Neuroscience

Attention-deficit/hyperactivity disorder (ADHD) is one of the most common disorders of childhood. It is theorized to be caused by catecholamine dysfunction in the striatum (Str) and frontal cortex (FC). The spontaneously hypertensive rat (SHR) has been used as a model for ADHD because of its attention deficits, impulsiveness, and hyperactivity. Prior studies of dopamine (DA) in the Str and FC have revealed conflicting results in the SHR compared to control, indicative of a need for a better understanding of DA dynamics in this model. In addition to the DA hypothesis, studies have begun implicating glutamate in the etiology of ADHD. …

Anxiety Disorders And School-Based Treatments: Assessing School Pyschologists' Knowledge And Perceptions, Kelly A. Myhasuk

PCOM Psychology Dissertations

Anxiety disorders are common in children and youth. Despite high prevalence rates, most children with anxiety disorders do not receive treatment. In fact, for the few children who are receiving treatment, schools are the primary source of mental health care. When left untreated, children experience significant disruptions in their academic, social, emotional, and behavioral functioning. Therefore, it is important for those working in schools to recognize and treat children with anxiety disorders. The present study surveyed school psychologists (n = 178) to assess their knowledge about anxiety disorders and about empirically supported school-based treatments. Also, this study sought to investigate …

Do N3 Fatty Acid Supplements Effect Depressive Symptoms Post Cardiovascular Event In Men And Women Ages 40 And Older?, Lindsey G. Caton

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not n-3 fatty acids have an effect on depressive symptoms post cardiovascular event in men and women ages 40 and older.

STUDY DESIGN: Systematic review of three English language random controlled trials published between 2011-2012.

DATA SOURCES: Two randomized controlled trials published after 2011 comparing the effects of n-3 fatty acid supplementation on depressive symptoms post cardiovascular event and one randomized controlled trial comparing n-3 fatty acid supplementation effects on depressive symptoms in elderly patients with diagnosed depression. The studies were obtained using the …

Is Animal Assisted Therapy Using Dogs An Effective Treatment For Positive And Negative Symptoms For Adult Inpatient Schizophrenics?, Brian Davidson

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not Animal Assisted Therapy (AAT) using dogs is an effective treatment for positive and negative symptoms for adult inpatient schizophrenics.

STUDY DESIGN: Systematic review of 3 articles published in English in peer reviewed journals between 2005-2009

DATA SOURCES: Two randomized controlled trials and one allocation by minimization controlled trial comparing the effects of AAT using dogs on positive and negative symptoms of schizophrenia to control groups. All articles were found using PubMed and PROQuest

OUTCOMES MEASURED: Focused questionnaires were given before and after …

Is The Use Of The Drug Buprenorphine And Naloxone (Suboxone) As Effective In Suppressing Opioid Dependency And Its Withdrawal Symptoms, Or Is It Simply A Surrogate For The Opiate With The Addictive Results?, Christina T. Lekas

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not the use of the drug Buprenorphine and Naloxone (Suboxone) is effective in suppressing opioid dependency and its withdrawal symptoms, or is it simply a surrogate for the opiate with the same addictive results.

STUDY DESIGN: Review of three primary studies in the English language published in 2010 and 2011.

DATA SOURCES: Randomized, controlled and double blind clinical trials evaluating the effectiveness of Suboxone in signs and symptoms of opioid withdrawal were found using the EBSCO Host and Lexi-Comp databases.

OUTCOMES MEASURED: Likability …

Is Melatonin An Effective Treatment For Sleep Problems In Autism?, Andrew J. Winkler

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not melatonin is an effective treatment for sleep problems in Autism.

STUDY DESIGN: Review of three English language, randomized controlled blinded trials published within peer-reviewed journals from 2006-2010 evaluating the efficacy of Melatonin as an oral sleep supplement in diagnosed autistic children.

DATA SOURCES: A double blind, randomized, placebo-controlled, crossover trial; a randomized controlled crossover trial; and a randomized controlled trial found using Cochrane, PubMed, and DynaMed.

OUTCOMES MEASURED: Total night’s sleep duration, number of awakenings, and sleep latency time were all measured …

Is Music Therapy A Complementary Treatment Option For Perinatal Women Experiencing Stress And Anxiety?, Samantha L. Wallace Mph

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not music therapy is a complementary treatment option for perinatal women experiencing stress and anxiety.

STUDY DESIGN: Literature review of three English language studies, published between 2006 and present.

DATA SOURCES: Three randomized controlled trials (RCTs) were found using a search of Pubmed, Medline, OVID, and Cochrane databases. These studies analyzed the use of a music therapy intervention among pregnant or postpartum women suffering stress, anxiety and/or depression.

OUTCOMES MEASURED: The outcomes of interest include stress, anxiety and severity of depression symptoms. Outcomes …

Inhibitory Control Deficits And Post-Traumatic Stress Disorder: Evidence From Eye Blink Rate, Mikael Rubin

Dissertations and Theses

No abstract provided.

Eating Disorder Onset In Young Girls: A Longitudinal Trajectory Analysis, Carolyn M. Pearson

Theses and Dissertations--Psychology

To investigate whether there are different patterns of development for binge eating and purging behavior among pre-adolescent and early adolescent girls, I conducted trajectory analyses of those behaviors in 938 girls across eight waves of data from the spring of 5^th grade (the last year of elementary school) through the spring of 9^th grade (the first year of high school). Analyses revealed four separate developmental trajectories for binge eating behavior (labeled none, increasing, decreasing, and high steady) and three separate developmental trajectories for purging behavior (labeled none, dabble, and increasing). Fifth grade scores on risk factors that were …

A Systems Biology Approach To Detect Eqtls Associated With Mirna And Mrna Co-Expression Networks In The Nucleus Accumbens Of Chronic Alcoholic Patients, Mohammed Mamdani

Theses and Dissertations

Alcohol Dependence (AD) is a chronic substance use disorder with moderate heritability (60%). Linkage and genome-wide association studies (GWAS) have implicated a number of loci; however, the molecular mechanisms underlying AD are unclear. Advances in systems biology allow genome-wide expression data to be integrated with genetic data to detect expression quantitative trait loci (eQTL), polymorphisms that regulate gene expression levels, influence phenotypes and are significantly enriched among validated genetic signals for many commonly studied traits including AD.

We integrated genome-wide mRNA and miRNA expression data with genotypic data from the nucleus accumbens (NAc), a major addiction-related brain region, of 36 …

Coping Responses And Mental Health Symptoms In Incarcerated Juvenile Males, Jennifer Renae Newhard

Antioch University Dissertations & Theses

Coping responses develop throughout the lifespan of an individual. Unfortunately for some, difficult life circumstances may lead to the use of maladaptive forms of coping. This study investigated coping responses amongst male incarcerated juvenile offenders and examined which specific mental health symptoms may occur with specific coping responses. The goal of this study was to determine whether male incarcerated juvenile offenders utilize avoidant coping responses over approach coping responses. Also, this study investigated whether specific mental health symptoms, such as depression, anxiety, anger, and disruptive behaviors, were more prevalent amongst those who utilize avoidant coping responses. De-identified, archival data for …