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Dynamic Cost-Effectiveness Of Oncology Drugs, Yang Lu, John Penrod, Neeraj Sood, Saarah Woodby, Tomas Philipson
Dynamic Cost-Effectiveness Of Oncology Drugs, Yang Lu, John Penrod, Neeraj Sood, Saarah Woodby, Tomas Philipson
Yang Lu
Objective: To develop a methodology for computing cost-effectiveness measures of a drug throughout its life cycle.
Study Design: We developed a set of models that measure the long-term cost-effectiveness of 2 oncology drugs, paclitaxel and docetaxel, throughout their life cycles.
Methods: The study combined pricing history of the drugs, US Food and Drug Administration approval dates, drug utilization from Medicare claims, and clinical effectiveness information from phase III studies reported in the scientific literature. These data were used to estimate the incremental cost-effectiveness ratio (ICER) at the time of market entry and by year thereafter. The study population included patients …