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2024

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Articles 31 - 33 of 33

Full-Text Articles in Natural Products Chemistry and Pharmacognosy

Chemical And Biological Investigation Of The Effects Of Vinegar Baking Sambucus Canadensis Anthocyanins, Elizabeth Martin Apr 2024

Chemical And Biological Investigation Of The Effects Of Vinegar Baking Sambucus Canadensis Anthocyanins, Elizabeth Martin

ATU Scholars Symposium

New treatments for cancer and bacterial infections are needed, especially because most patients acquire resistance to conventional first-line treatments. Many natural product metabolites exhibit potent activity. Sambucus sp., elderberry, and Salvia sp., or sage, are well-known shrubs for their therapeutic benefits. This study aims to analyze how secondary metabolites are extracted from the native American Elderberry, Sambucus canadensis, and Sage, Salvia officinalis. It also aims to investigate the process of vinegar baking of medicinal plants to enhance the chemical space and increase the biological properties. Vinegar baked and non-vinegar baked elderberries and sage were utilized to test this theory. …


The Quantification Of Essential Oils And Bixin In Annatoo Seeds, Alycia C. Johnson, Susan Oxley Apr 2024

The Quantification Of Essential Oils And Bixin In Annatoo Seeds, Alycia C. Johnson, Susan Oxley

Posters - 2024

Bixa orellana (also known as annatto or achiote) originates from South America but it can be found nearly everywhere in the world. The seeds of this species make for an excellent natural coloring. It is applied to makeup, food, and textiles; some of the biggest commercial industries.1 Of the 50+ phytochemicals identified, there are a large number of essential oils and other compounds that have been shown to have beneficial properties. Four of these compounds will be used to determine which traditional processing method results in the biggest loss of phytochemicals. Annatto is often either fried, left whole, or powdered …


Advancements In The Synthesis Of Polyoxygenated Oxepanes And Thiepanes For Applications To Natural Products, Aditya R. Pote, Shayne M. Weierbach, Mark W. Peczuh, Kyle M. Lambert Jan 2024

Advancements In The Synthesis Of Polyoxygenated Oxepanes And Thiepanes For Applications To Natural Products, Aditya R. Pote, Shayne M. Weierbach, Mark W. Peczuh, Kyle M. Lambert

Chemistry & Biochemistry Faculty Publications

Oxepanes are central motifs and tenants of many biologically important molecules, and their synthetic construction often presents a challenge to chemists due to consequential entropic and enthalpic barriers that have limited the synthetic toolbox to access these seven-membered oxacycles. This review covers the breadth of synthetic methods to afford the oxepane/thiepane moiety, with a focus on polyoxygenated oxepanes and includes radical cyclizations, Lewis acid-mediated cyclizations, ring closing-metathesis, Nicholas-Ferrier rearrangement, homologations, and ring-expansion strategies. Implementation of these tactics towards sugar-based and non-sugar based (de novo) approaches is presented alongside their extensive application to the total synthesis of several complex polyoxygenated oxepane-containing …