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Articles 151 - 156 of 156
Full-Text Articles in Natural Products Chemistry and Pharmacognosy
Tablet Effervescent Ekstrak Belimbing Wuluh (Averrhoa Bilimbi L.) Dengan Variasi Kadar Pemanis Aspartam, Rosmala Dewi, Iskandarsyah Iskandarsyah, Devi Octarina
Tablet Effervescent Ekstrak Belimbing Wuluh (Averrhoa Bilimbi L.) Dengan Variasi Kadar Pemanis Aspartam, Rosmala Dewi, Iskandarsyah Iskandarsyah, Devi Octarina
Pharmaceutical Sciences and Research
Averrhoa bilimbi is fruit that has many benefits but the usage is not optimal. That is why the aim of the research is to get formulation of effervescent granule and tablet containing dry Averrhoa bilimbi extract with modified concentration of aspartame as sweetening agent for commercial healthy drink. Granules and tablets were produced with dry method granulation with 40% of relative humidity (RH) and 25ºC of temperature. The three of formulation were qualified as effervescent granules and tablets. Favorite tests showed that no significant differences of appearances, tastes for three of effervescent granules and tablets.
Respon Bioakumulator Eceng Gondok (Eichhornia Crassipes) Terhadap Logam Berat Pb Dan Cd Di Sungai Pegangsaan Dua, Sri Teguh Rahayu, Meutia Faradilla, Ester Yani Verawati, Muchrip Triana
Respon Bioakumulator Eceng Gondok (Eichhornia Crassipes) Terhadap Logam Berat Pb Dan Cd Di Sungai Pegangsaan Dua, Sri Teguh Rahayu, Meutia Faradilla, Ester Yani Verawati, Muchrip Triana
Pharmaceutical Sciences and Research
Eichhornia crassipes is one of Indonesia’s wild plant that considered as weed. Its presence can disrupt ecosystems in the river. However, it is proven to absorb Pb and Fe. It is also believed that E.crassipes can absorb other metals such as Hg , Zn , Cu and Cd which were belong to the same group as Pb and Fe. In addition to heavy metal sequestration, Eichhornia crassipes can also absorb pesticide residues. This descriptive research was done to determine the bioaccumulator response to Pb and Cd in Pegangsaan Dua river using Inductively Coupled Plasma method. Bioaccumulator response of Eichhornia crassipes …
Formulasi Gel Pacar Air (Impatiens Balsamina Linn.) Terhadap Propionibacterium Acnes Dan Staphylococcus Epidermidis, Diah Ismarani, Liza Pratiwi, Indri Kusharyanti
Formulasi Gel Pacar Air (Impatiens Balsamina Linn.) Terhadap Propionibacterium Acnes Dan Staphylococcus Epidermidis, Diah Ismarani, Liza Pratiwi, Indri Kusharyanti
Pharmaceutical Sciences and Research
Acnes vulgaris is a chronic inflammatory disease of sebaceous follicles caused by Propionibacterium acnes and Staphylococcus epidermidis. The antibacterial activity of Impatiens balsamina L. has been studied for many years. The aims of this study are to find out the antiacne effect from methanolic extract of stems and leaves of Impatiens balsamina L. that formulated in gel. Simplicia were extracted using soxhlet technique bu using methanol as solvent. Extracts were then formulated in gel in three variations of HPMC 4000 and Carbopol 934 as gel base with ratio of 70:30 (F1), 50:50 (F2) and 30:70 (F3). The determination of antiacne …
Uji Aktivitas Antibakteri 1-[(Kuinazolin-4-On-2-Il)Metil]Piridin-1-Ium Bromida Dan 2-Bromometilkuinazolin-4-On, Hayun Hayun, Arif Arrahman, Herman Suryadi, Arry Yanuar
Uji Aktivitas Antibakteri 1-[(Kuinazolin-4-On-2-Il)Metil]Piridin-1-Ium Bromida Dan 2-Bromometilkuinazolin-4-On, Hayun Hayun, Arif Arrahman, Herman Suryadi, Arry Yanuar
Pharmaceutical Sciences and Research
Antibacterial activity tests of quinazolin-4-one derivates: 1-[(6-nitroquinazolin-4one-2-yl)methyl]piridin-1-ium bromide (1), 1-[(6-aminoquinazolin-4-on-2-yl)methyl] piridin-1-um bromide (2), 2-bromomethylquinazolin-4-one (3) and 2-bromomethyl-6nitroquinazolin-4-one(4) with trimethoprim (5) as a positive standard were conducted. The antibacterial activity tests were carried out using disc diffusion method againts E.coli, S.aureus and S.thyposa, and determination of minimum inhibitory concentration (MIC). The results showed that compounds 1 and 2 are inactive as antibacterial, whereas compounds 3 and 4 are active.The activities to E.coli were ¼ times the activity of trimethoprim (MIC : 5 x 102 µg/ml compared to 1.25 x 102 µg/ml ). The activity to S. typhosa were ½-1 times the …
Uji Toksisitas Fraksi Air Impatiens Balsamina Pada Tikus Betina Galur Sprague Dawley, Entang Nurqolbiah, Indri Kusharyanti, Siti Nani Nurbaeti
Uji Toksisitas Fraksi Air Impatiens Balsamina Pada Tikus Betina Galur Sprague Dawley, Entang Nurqolbiah, Indri Kusharyanti, Siti Nani Nurbaeti
Pharmaceutical Sciences and Research
The present study was aimed to predict the level of toxicity of aqueous fraction of Impatiens balsamina by acute toxicity study using OECD guideline 425. Female Sprague Dawley 8-12 week and weight between 140-170 gram were used, the amount of experimental rats were 10 rats. Rats were sequentially administered all the fraction in single dosage (limit test) of 2000 mg/kg body weight and 5000 mg/kg of body weight. All the animals were individually studied for mortality, wellness parameters, food consumption,water consumption, body weight. Histopathological examination was done on the liver and kidney. The result of this study showed that no …
Pengaruh Natrium Hialuronat Terhadap Penetrasi Kofein Sebagai Antiselulit Dalam Sediaan Hidrogel, Hidroalkoholik Gel, Dan Emulsi Gel, Joshita Djajadisastra, Zuraida Syafara Dzuhro, Sutriyo Sutriyo
Pengaruh Natrium Hialuronat Terhadap Penetrasi Kofein Sebagai Antiselulit Dalam Sediaan Hidrogel, Hidroalkoholik Gel, Dan Emulsi Gel, Joshita Djajadisastra, Zuraida Syafara Dzuhro, Sutriyo Sutriyo
Pharmaceutical Sciences and Research
Anticellulite topical gel preparation with caffeine as active ingredient needs a penetration enhancer to reach subcutaneous layer. Sodium hyaluronate (NaHA), the sodium salt of hyaluronic acid, is a hydrophilic polysaccharide derivative polymer. It has ability to enhance percutaneous penetration by loosening the dense of the compact substance stratum corneum. The aim of this research was to observe the effects of NaHA on caffeine penetration as anticellulite active agent in three types of gel preparation: hydrogel, hydroalcoholic gel, and gel emulsion. Each gel type contained caffeine 1,5% and was varied into three formulas. Formula 1 contained HPMC 2% as gel basis; …