Open Access. Powered by Scholars. Published by Universities.®
Natural Products Chemistry and Pharmacognosy Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Alternative and Complementary Medicine (2)
- Medical Pharmacology (2)
- Medical Sciences (2)
- Medical Specialties (2)
- Pharmaceutics and Drug Design (2)
-
- Behavioral Neurobiology (1)
- Biochemistry, Biophysics, and Structural Biology (1)
- Chemicals and Drugs (1)
- Endocrinology (1)
- Life Sciences (1)
- Medicinal and Pharmaceutical Chemistry (1)
- Molecular Biology (1)
- Nephrology (1)
- Neuroscience and Neurobiology (1)
- Oncology (1)
- Pharmaceutical Preparations (1)
- Physiology (1)
- Public Health (1)
- Women's Health (1)
- Keyword
-
- Adaptogen (1)
- Alternative and complementary medicine (1)
- Anti-angiogenesis (1)
- Anti-proliferation (1)
- Apoptosis (1)
-
- Ashwagandha (1)
- Biomedical Engineering (1)
- Black rice extract (1)
- CB1 receptors (1)
- Cancer (1)
- Celastrol (1)
- Chemotherapeutics (1)
- Colon cancer (1)
- Diuresis (1)
- Eastern herbal medicine (1)
- Efficacy (1)
- FAAH (1)
- Flibanserin (1)
- Medullary interstitial cells (1)
- Natriuresis (1)
- PF-3845 (1)
- Renal medulla (1)
- Sesamol (1)
- Sexual Desire (1)
- Sexual Health (1)
- Synergistic effects (1)
- T. wilfordii (1)
- Triptolide (1)
- Vasodilation (1)
- Publication
- Publication Type
Articles 1 - 4 of 4
Full-Text Articles in Natural Products Chemistry and Pharmacognosy
Ashwagandha And Sexual Health In Women With Hypoactive Sexual Desire Disorder: Exploring Extent Of Adaptogenic Properties, Rhea Chatterjee
Ashwagandha And Sexual Health In Women With Hypoactive Sexual Desire Disorder: Exploring Extent Of Adaptogenic Properties, Rhea Chatterjee
AUCTUS: The Journal of Undergraduate Research and Creative Scholarship
Hypoactive Sexual Desire Disorder (HSDD) affects 40% of women and potentially decreases their quality of life. Currently, the primary treatment for HSDD is Flibanserin, which is a serotonergic agonist and an antidepressant. However, the limited efficacy of Flibanserin encourages the exploration of the utilization of traditional drugs such as Withania somnifera, otherwise known as Ashwagandha, as an alternative treatment for HSDD. Minimal studies examine ayurvedic medications or the symptoms of illnesses that traditional Western medicines are unable to treat. This comprehensive literature review investigated the efficacy of Ashwagandha in improving sexual function in women with HSDD. The paper evaluated …
Testing The Efficacy And Synergistic Components Of Sesamol And Black Rice Extract On Human Colon Cancer Cells, Sera Lim, Philip M. Gerk
Testing The Efficacy And Synergistic Components Of Sesamol And Black Rice Extract On Human Colon Cancer Cells, Sera Lim, Philip M. Gerk
UROP Posters
Purpose: Systemic treatment of colorectal cancer involves chemotherapeutic agents which elicit serious and negative side effects from the toxicity of the drug. To address this issue, we are testing dietary supplements for their efficacy against human colon cancer cell lines and also their potential synergistic effects when combined with conventional chemotherapy. Dietary supplements (specifically sesamol and black rice extract) exhibit anticancer, anti-inflammatory, and chemo-preventive properties. Meanwhile, one of the cancer resistance mechanisms is the upregulation of drug elimination mechanisms, leading to multi-drug resistance. We hypothesize that dietary compounds will act as chemo-enhancers, thus enhancing potency of the chemotherapy drug(s) on …
Diuretic, Natriuretic, And Vasodepressor Activity Of A Lipid Fraction Enhanced In Medium Of Cultured Mouse Medullary Interstitial Cells By A Selective Faah Inhibitor, Zdravka P. Daneva
Diuretic, Natriuretic, And Vasodepressor Activity Of A Lipid Fraction Enhanced In Medium Of Cultured Mouse Medullary Interstitial Cells By A Selective Faah Inhibitor, Zdravka P. Daneva
Theses and Dissertations
The relationship between the endocannabinoid system in the renal medulla and the long-term regulation of blood pressure is not well understood. To investigate the possible role of the endocannabinoid system in renomedullary interstitial cells, mouse medullary interstitial cells (MMICs) were obtained, cultured and characterized for their responses to treatment with a selective inhibitor of fatty acid amide hydrolase (FAAH), PF-3845. Treatment of MMICs with PF-3845 increased cytoplasmic lipid granules detected by Sudan Black B staining and multilamellar bodies identified by transmission electron microscopy. HPLC analyses of lipid extracts of MMIC culture medium revealed a 205nm-absorbing peak that showed responsiveness to …
Feasibility Of Integrating Tripterygium Wilfordii Into Modern Cancer Therapy For Increased Efficacy And Minimal Toxicity, Ngoc T. Vo
UROP Posters
Cancer is the second leading cause of death in the U.S. and millions of novel cancer cases are being diagnosed each year. While chemotherapy and ionizing radiation are effective treatments against these malignant tumors, the adverse effects that accompany such treatments are devastating. In order to find alternative treatment methods with less side effects, we turn to Eastern herbal medicine. Recent scientific research has found that Tripterygium wilfordii, an herbal medicine traditionally used to treat inflammation in China, contains compounds (triptolide and celastrol) that prevent the growth of solid tumors, induce apoptosis, and prevent metastasis of developed tumors. Investigations …