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Clinical Risk Assessment In Early Pregnancy For Preeclampsia In Nulliparous Women: A Population Based Cohort Study, Anna Sandstrom, Jonathan Snowden, Jonas Höijer, Matteo Bottai, Anna-Karin Wikström
Clinical Risk Assessment In Early Pregnancy For Preeclampsia In Nulliparous Women: A Population Based Cohort Study, Anna Sandstrom, Jonathan Snowden, Jonas Höijer, Matteo Bottai, Anna-Karin Wikström
OHSU-PSU School of Public Health Faculty Publications and Presentations
Objective
To evaluate the capacity of multivariable prediction of preeclampsia during pregnancy, based on detailed routinely collected early pregnancy data in nulliparous women.
Design and setting
A population-based cohort study of 62 562 pregnancies of nulliparous women with deliveries 2008–13 in the Stockholm-Gotland Counties in Sweden.
Methods
Maternal social, reproductive and medical history and medical examinations (including mean arterial pressure, proteinuria, hemoglobin and capillary glucose levels) routinely collected at the first visit in antenatal care, constitute the predictive variables. Predictive models for preeclampsia were created by three methods; logistic regression models using 1) pre-specified variables (similar to the Fetal Medicine …