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Special Edition 1979, Southwestern Oklahoma State University

The Sig

The Sig Newsletter from the Southwestern Oklahoma State University College of Pharmacy - Special Edition 1979

Winter 1979, Southwestern Oklahoma State University

The Sig

The Sig Newsletter from the Southwestern Oklahoma State University College of Pharmacy - Winter 1979

[Beta]-(2-Hydroxyphenyl)Ethanolamine Hydrochloride [2-Amino-1-(2-Hydroxyphenyl)Ethanol Hydrochloride], Alexandros Makriyannis, James B. Anderson, Joseph T. Dipiro, Edward Kostiner, Gilbert Hite

Publications from the Office of the Dean

CsH~2NO2+.C1 -, m.p. 441-449 K (from ethyl acetate), P212~2 l, a = 7.363 (2), b = 21.824 (6), c = 5.790 (2)/~, Z = 4, D x = 1.354, D m = 1.356 Mg m -3 (flotation: CC14-C6H6). The structure was solved by MULTAN. Full-matrix least-squares refinement converged to R = 0.057 for the R configuration and to R = 0.056 for the S configuration (P < 0.05). This is consistent with spontaneous resolution of the title compound, single crystals of which provided optically active aqueous solutions. A partially occupied oxygen site O(1)' is attributed to the oxidation of the alkyl hydroxyl group to a ketone during the data collection. The CI- is hydrogen bonded to H2(N)554, H3(N)555, and 1-t(O2)655 (2.37, 2-19, and 2.10 A). Both O(1) and 0(2) are internally hydrogen bonded [HI(N)...O(1), 2.41 and H(O1)...O(2) = 2.24 A]. Intramolecular hydrogen bonding may account for the unusual pharmacological properties of this compound in which only the N-C(1)-C(2)-O(1) and the O(1)-C(2)- C(3)-C(4) and O(1)-C(2)-C(3)-C(8) torsion angles (-41, -60, +122 ° ) differ significantly from those of other phenylethanolamines.

Behavioral Pharmacy, C. Anderson Johnson, Albert I. Wertheimer

CGU Faculty Publications and Research

In the text that follows, the development of a coherent and recognizable teaching and research field devoted to the development of the behavioral and social sciences in pharmacy is proposed. It is important for teachers and researchers in this field to establish a common and recognizable identity; to share basic definitions, purposes and criteria; and to develop forums (such as scientific meetings ·and perhaps a journal) for the exchange and nourishment of the behavioral science knowledge that they generate. It is suggested that this field be called behavioral pharmacy. This title is suggested primarily because Of recent· participant agreement and …

The Changing Role Of Pharmacists As Evidenced By The Strong Vocational Interest Blank, C. Anderson Johnson, Timothy R. Church, Albert I. Wertheimer, Clayton R. Rowland

CGU Faculty Publications and Research

The Strong Vocational Interest Blank/Strong Campbell Interest Inventory-Merged Form, or simply Strong Vocational Interest Blank (SVIB), is widely used to determine the suitability of a student's interests to a particular field. In the process of norming the instrument, data concerning the satisfaction of practitioners of a field and their responses on the instrument are gathered. Such data lend themselves to analysis of trends in the characteristics of those practitioners both over time and over the satisfaction spectrum. Hence changes in the field and characteristics lending themselves to satisfaction can be ascertained.

1979 Apothecary, Southwestern Oklahoma State University

Apothecary

THE APOTHECARY wishes to offer congratulations to the graduating seniors of the School of Pharmacy. During the last five years, you have learned the lessons which have qualified you to become members of an important profession. Also, enduring bonds of friendship have been tied between teachers and classmates. We all realize these have been tremendous and exciting years.

Biofeedback Treatment Of A Drug Induced Tremor, Ralph Nitta

University of the Pacific Theses and Dissertations

Two subjects exhibiting drug-induced hand tremor received EMG feedback from electrode sites above the forearm extensor muscles . EMG feedback resulted in reductions in muscle potentials for both subjects. However, self-report measures of tremor severity showed only general improvement in Subject l and little or no improvement in Subject 2. Behavioral measures of hand steadiness taken immediately after each treatment session showed slight changes across treatment conditions for both subjects. As indicated by a rapid increase in EMG measures during reversal, treatment effects appear transitory.

Investigation Of Lanolin Alcohol As A Film-Forming Delivery System: In Vitro Kinetics Of Triamcinolone Acetonide Release And Skin Penetration., Balasubramanian Venkataraman Iyer

University of the Pacific Theses and Dissertations

The nonpolymeric high molecular weight substances such as lanolin alcohol, stearyl alcohol, and cetyl alcohol have been investigated for their film-forming potential. Furthermore, the application of this potential in the design of topical drug-delivery systems has also been explored. The utilization of such film-forming systems may offer certain unique advantages not associated with the polymeric systems.

Stearyl alcohol and cetyl alcohol do not form films of acceptable integrity. Lanolin alcohol forms thin films capable of being isolated. Inclusion of appropriate amounts of ethyl cellulose and propylene glycol or hexadecyl alcohol in lanolin alcohol was found to improve the integrity, hardness …