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Biodegradable, Low Biological Toxicity Radiographic Contrast Medium And Method Of X-Ray Imaging, Michael J. Jay, Yun Ryo
Biodegradable, Low Biological Toxicity Radiographic Contrast Medium And Method Of X-Ray Imaging, Michael J. Jay, Yun Ryo
Pharmaceutical Sciences Faculty Patents
A biodegradable, low biological toxicity, particulate radiographic contrast medium comprises biodegradable polymeric spheres of average molecular weight average diameter about 10-1,000 nm or about 0.01-1.0 micron carrying in at least radiographic contrasting amount of a radiographically opaque element.
A method of obtaining a tomographic image of the body portion of a subject comprises administering to the subject a radiographically-detectable amount of the biodegradable, low-toxicity radiographic medium of claim 1; allowing for the spheres to be taken-up by the body portion; and X-raying an area comprising the body portion.
A method of improving the contrast of a tomographic image of a …