Pharmacy and Pharmaceutical Sciences Commons^™

Systematic Review And Meta-Analysis Of The Correlation Between Bispectral Index (Bis) And Clinical Sedation Scales: Toward Defining The Role Of Bis In Critically Ill Patients., Mojdeh S Heavner, Emily F Gorman, Dustin D Linn Pharm D, Siu Yan Amy Yeung, Todd A Miano

Parkview Pharmacy Department

INTRODUCTION: The bispectral index (BIS) is an attractive approach for monitoring level of consciousness in critically ill patients, particularly during paralysis, when commonly used sedation scales cannot be used.

OBJECTIVES: As a first step toward establishing the utility of BIS during paralysis, this review examines the strength of correlation between BIS and clinical sedation scales in a broad population of non-paralyzed, critically ill adults.

METHODS: We included studies evaluating the strength of correlation between concurrent assessments of BIS and Richmond Agitation Sedation Scale (RASS), Ramsay Sedation Scale (RSS), or Sedation Agitation Scale (SAS) in critically ill adult patients. Studies involving …

Implementing Services For Pediatric Cystic Fibrosis Treatment In A Community Hospital, Paige M. Grube Pharmd

Parkview Pharmacy Department

Presented at the 36th Great Lakes Pharmacy Residency Conference.

Ketorolac Ceiling Dose Implementation In The Emergency Department, Abigail Geyer Pharmd

Parkview Pharmacy Department

Presented at the 36th Great Lakes Pharmacy Residency Conference

Osteoporosis: Closing Gaps In Care To Improve Value-Based Contract Measure Outcomes, Zachary Brown Pharmd

Parkview Pharmacy Department

Presented at the 36th Great Lakes Pharmacy Residency Conference.

Evaluation Of A Pharmacy-Led Statin Medication Use Review And Outreach Initiative, Megan Wagner Pharmd

Parkview Pharmacy Department

Presented at the 36th Great Lakes Pharmacy Residency Conference.

Development Of A Tool To Assess Hypoglycemia Risk In Patients With Type 2 Diabetes, Katherine Brown Pharmd

Parkview Pharmacy Department

Presented at the 36th Great Lakes Pharmacy Residency Conference.

Evaluation Of A Pharmacist-Led Health Literacy Workflow In The Ambulatory Clinic, Alexis Mann Pharmd, Mba

Parkview Pharmacy Department

Presented at the 36th Great Lakes Pharmacy Residency Conference.

Multicenter Retrospective Review Of Ketamine Use In The Icu., Christine M Groth, Christopher A Droege, Kathryn A Connor, Kimberly Kaukeinen, Nicole M Acquisto, Sai Ho J Chui, Michaelia D Cucci, Deepali Dixit, Alexander H Flannery, Kyle A Gustafson, Nina E Glass, Helen Horng, Mojdeh S Heavner, Justin Kinney, Rachel M Kruer, William J Peppard, Preeyaporn Sarangarm, Andrea Sikora, Velliyur Viswesh, Brian L Erstad, Parkview Health

Parkview Pharmacy Department

This publication is included in our collection because several Parkview pharmacists were involved in the data collection part and acknowledged for the assistance they provided to the overall article. See Comment.

The response of ICU patients to continuously infused ketamine when it is used for analgesia and/or sedation remains poorly established.

OBJECTIVES: To describe continuous infusion (CI) ketamine use in critically ill patients, including indications, dose and duration, adverse effects, patient outcomes, time in goal pain/sedation score range, exposure to analgesics/sedatives, and delirium.

DESIGN SETTING AND PARTICIPANTS: Multicenter, retrospective, observational study from twenty-five diverse institutions in the United States. Patients …

Fanconi Syndrome Leading To Hypophosphatemic Osteomalacia Related To Tenofovir Use., Mana Rao, Liam Dadey, Thomas Glowa, Peter Veldkamp

Parkview Pharmacy Department

Tenofovir disoproxil fumarate (TDF) is used worldwide to treat and prevent Human Immunodeficiency Virus (HIV) infection. Fanconi syndrome is a complication of TDF use and is characterized by inadequate reabsorption of glucose, phosphate and protein in the proximal tubule of the kidney which may eventually lead to osteomalacia manifested by symptoms of pain, muscular weakness and difficulty ambulating. We present a patient with severe osteomalacia due to progressive and unrecognized Fanconi's syndrome, who responded rapidly to TDF withdrawal, oral phosphate repletion and calcitriol. With the widespread use of TDF-containing antiviral regimens, it is critically important that physicians adhere to screening …

Intravenous Smart Pumps During Actual Clinical Use: A Descriptive Comparison Of Primary And Secondary Infusion Practices., Karen K Giuliano, Daleen Penoyer, Rebecca S. Mahuren, Melody Bennett

Parkview Pharmacy Department

This descriptive observational study was conducted to increase understanding of medication administration practices during actual clinical use between 2 commonly used, different types of intravenous (IV) smart pumps. Compliance with manufacturer-recommended setup requirements for both primary and secondary infusions and secondary medication administration delay was compared between a head-height differential system and a cassette system. A total of 301 medication administration observations were included in this study: 102 (34%) for the linear peristaltic IV smart pump (medical-surgical: N = 51; critical care: N = 51) and 199 (66%) for the cassette pump (medical-surgical: N = 88; critical care: N = …

Pharmacist Impact On Cardiology Bundle Payments For Care Improvement And Patient Outcomes, Megan Wagner Pharmd, Jordan Holder Pharmd, Priya Verma Pharmd, Bcacp

Parkview Pharmacy Department

2021 ASHP Midyear Clinical Meeting - Poster ID:1127833

Background: The Medicare Bundle Payments for Care Improvement (BPCI) Initiative was created to better the transitions of care process, incentivize hospitals to reduce readmission rates, and improve overall care in hospitals nationwide.• As this payment structure has incorporated additional diagnoses, it has become a popular focus of research into interprofessional and pharmacy-based interventions to reduce readmission rates. • Data shows that pharmacist-led interventions during transitions of care can significantly contribute to decreased readmission rates. • This study examines the review process of the ambulatory-based cardiology pharmacists at Parkview Health in evaluating cardiology …

Evaluation Of Benefits Associated With Chemotherapy Dose-Banding Practices, Alexis Mann Pharmd, Mba, Kyle Becker Pharmd, Mba, Bcop, Jesse Christman Pharmd, Bcop

Parkview Pharmacy Department

2021 ASHP Midyear Clinical Meeting / Virtual Meeting / Poster # 1130014

The objective of this study was to evaluate the benefit of applying a 10% rounding strategy with predetermined dose-bands to the current chemotherapy dosing policy at Parkview Health.

Characterization Of Infliximab And Biosimilar Use In A Community Health System, Abigail Geyer Pharmd, Luke Keller Pharmd, Bcps, Bcccp, Curtis Stump Pharmd, Renu Johnson Pharmd, Bcps

Parkview Pharmacy Department

2021 ASHP Midyear Clinical Meeting / Virtual / Poster #1129769

Objective: To identify characteristics of infliximab and relevant biosimilar use within a community health system.

Rasburicase Utilization After Protocol Implementation Focused On Fixed Dosing By Limiting Use Of Weight-Based Dosing To Oncology Providers, Dakota Smith Bs, Jamie Gaul Pharmd, Bcps, Liam Dadey Pharmd, Bcps

Parkview Pharmacy Department

Dec 2021 ASHP Midyear Clinical Meeting / Poster

Objective: Evaluate the change in rasburicase use pre- and post-implementation of dosing restriction protocol.

Comparison Of Standard Dose Vs Higher Dose Low Molecular Weight Heparin And Unfractionated Heparin For Dvt Prophylaxis In Covid-19 Patients, Zachary Brown Pharmd, Munyaradzi Chakabva Md, Tabinda Akhtar Md, Sarah Polina Pharmd, Bcps, Michael Todt Pharmd, Bcccp, Mckenna Brauner Np, Meghan Mcguire Np, Aws Polina Md

Parkview Pharmacy Department

2021 ASHP Midyear Clinical Meeting / Virtual / Poster # 1121810

Objective: To evaluate whether higher dose VTE prophylaxis results in a significant reduction in VTE events without significant increase in bleeding risk when compared to standard dose VTE prophylaxis in patients with COVID-19 infection

Indomethacin Suppository Medication Use Evaluation For Prevention Of Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis (Pep) In A Community Health System, Caitlyn Patton, Jamie Gaul Pharmd, Bcps, Jennifer Sposito Pharmd

Parkview Pharmacy Department

2021 ASHP Midyear Clinical Meeting / Virtual / Poster

Objective: To evaluate the use and characterize the patient population receiving indomethacin suppositories for PEP with the goal of ensuring appropriate use.

Assessing Consistency With Standards Of Care Recommendations For Patients With Type 2 Diabetes At Hospital Discharge, Katherine Brown Pharmd, Timothy L. Johnston Bpharm, Pharmd, Bcps, Bcccp, Andrea Sloat Pharmd

Parkview Pharmacy Department

2021 ASHP Midyear Clinical Meeting / Poster ID#1129514

Objective: To assess the number of patients prescribed diabetic regimens consistent with American Diabetes Association (ADA) Standards of Care recommendations upon hospital discharge.

Implementation And Outcomes Assessment Of A 4-Factor Prothrombin Complex Concentrate (4f-Pcc) Tiered Fixed Dosing Protocol In A Health System., Mark Botros Bs, Jamie Gaul Pharmd, Bcps, Dana Lorber Pharmd, Bcps, Sarah Koontz Pharmd, Bcps

Parkview Pharmacy Department

2021 ASHP Midyear Clinical Meeting / Poster

The aim of this study was to evaluate compliance to the newly implemented fixed dosing protocol while assessing for the need for repeat doses of 4F-PCC and the need for further invasive intervention to reverse the bleeding.

Evaluation Of Intravenous Immunoglobulin (Ivig) Utilization After The Implementation Of Indication And Dosing Protocol At A Community Health System., Nicholas Buttermore, Jamie Gaul Pharmd, Bcps, Kate Oetting

Parkview Pharmacy Department

2021 ASHP Midyear Clinical Meeting / Poster

Objective: This study was conducted to evaluate the patient landscape of IVIG use within our community health system, both before and after protocol implementation. Our goals were to identify potential changes with the indication for use along with any prescribed dosing decreases while under protocol.

Evaluation Of Calcitonin Use For Hypercalcemia At Parkview Health, Alison Rydell, Jesse Christman Pharmd, Bcop, Jamie Gaul Pharmd, Bcps

Parkview Pharmacy Department

2021 ASHP Midyear Clinical Meeting / Poster

Objective: Evaluate the appropriateness of calcitonin use for hypercalcemia at Parkview Health, a not-for-profit community hospital health system.

Evaluation Of Emergency Department Treatment Of Pediatric Asthma Exacerbations, Paige Walker Pharmd, Amber Ooley Pharmd, Bcps, Bcccp, Kassandra Foellinger Pharmd, Bcps

Parkview Pharmacy Department

Objective:

Primary: to assess the appropriateness of medications ordered in the emergency department (ED).

Secondary: to assess the appropriateness of discharge medications and new encounters within 30 days for another asthma-related problem.

Implementation Of Order Sets For Opioid Alternatives In Community Hospital Emergency Departments., Jared Netley Pharmd, Mpa, Bcps, Bcccp, William Armstrong Pharmd, Bcps, Sarah Meeks Pharmd

Parkview Pharmacy Department

PURPOSE: The design and implementation of alternatives to opioids (ALTO) order sets for the treatment of acute pain in a community health system's emergency departments are described.

SUMMARY: Healthcare institutions nationwide have incorporated policies and procedures to assist prescribers in the safe and effective management of pain. These adopted approaches may be targeted at mitigating opioid prescribing as well as promoting the optimization of nonopioid analgesics. Institutions that enact innovations and track outcomes may be eligible for reimbursement through the Centers for Medicare and Medicaid Services' Merit-based Incentive Payment System. Emergency departments may monitor implementation progress and outcomes through participation …

Characterization Of Antibiotic Use And Culture Data In Covid-19 Pandemic Patients, Ashley Logan Pharmd, Stacy Clore Pharmd, Bcps, Alissa Keillor Pharmd

Parkview Pharmacy Department

Poster Presentation

2020 ASHP Midyear Clinical Meeting / Virtual / Poster # RP-609

Objective: The objective of this study was to identify the prevalence of bacterial, viral, or fungal coinfections and to describe the empiric antimicrobial regimens in patients with confirmed COVID-19.

Assessing Duration Of Therapy Recommendations Based On Clostridium Difficile Guidelines Within The Parkview Health System, Curtis Stump Pharmd, Trent Towne Pharmd, Bcps, Aubrey Mills Pharmd

Parkview Pharmacy Department

2020 ASHP Midyear Clinical Meeting / Virtual / Poster

Objective: The objective of this study was to evaluate the appropriateness of first episode CDI treatment (non-severe and severe cases) within the Parkview health system

Evaluation Of Pharmacy To Dose Heparin Protocol In Neurological Conditions, Leslie Siegel Pharmd, Timothy L. Johnston Pharmd, Karen Dunkelberger Bs Pharm, Mshi, Cpps

Parkview Pharmacy Department

2020 ASHP Midyear Clinical Meeting / Virtual / Poster

The objective of this study was to assess the safety and efficacy of the current pharmacy to dose heparin protocol for neurological conditions.

Evaluation Of The Diagnosis And Treatment Of Asymptomatic Bacteriuria At A Community Hospital, Halie Mcmillan, Abby L. Todt Pharmd, Bcps, Sarah Ferrell Pharmd, Jamie Gaul Pharmd, Bcps

Parkview Pharmacy Department

2020 ASHP Midyear Clinical Meeting / Virtual Meeting / Poster #SP-511

Objective: To evaluate the diagnosis and treatment of asymptomatic bacteriuria (ASB) within a community hospital setting.

Evaluation Of Dexmedetomidine Use As An Adjunctive Therapy In The Management Of Alcohol Withdrawal Syndrome, Zsanett Kormanyos Pharmd, Dustin D. Linn Pharmd, Bcps, Bcccp, Jillian Coons Pharmd, Bcps

Parkview Pharmacy Department

2020 ASHP Midyear Clinical Meeting / New Orleans, Louisiana / Poster # RP-606

The objective of this medication use evaluation (MUE) was to assess the utilization and outcomes associated with dexmedetomidine in the treatment of alcohol withdrawal syndrome

Impact Of Extended Interval Inr Testing During The Covid-19 Pandemic, Jordan Holder Pharmd, Maryam Noureldin Pharmd, Bcps,Bcacp, Priya Verma Pharmd

Parkview Pharmacy Department

2020 ASHP Midyear Clinical Meeting

Objective: To determine if extended INR interval monitoring during the COVID-19 pandemic would significantly impact TTR or be associated with emergency department (ED) visits and hospitalizations with bleeding or clotting events.

An Evaluation Of Vancomycin Use In Patients With Urosepsis, Curtis Stump Pharmd, Shahinda Mohmed, Dustin D Linn Pharmd, Rph, Bcccp

Parkview Pharmacy Department

Poster Presentation

Background and Objective:

Urosepsis is an infection that originates from the urinary tract and accounts for 9% of all sepsis cases. 1 Pathogens commonly associated with urosepsis include E. coli, Proteus spp., Enterobacter spp., Klebsiella spp., and P. aeruginosa, and gram-positive bacteria (5% of cases). Sepsis treatment guidelines do not provide specific recommendations for the management of urosepsis; however, they state to utilize anti-MRSA agents, such as vancomycin, when risk factors for MRSA exist. 2 The prevalence of urosepsis caused by gram-positive organisms has been reported at low rates. The objective of this study is to evaluate how …

Implementation Of A Pediatric Pharmacy Education Program At A Community Regional Medical Center., Chelsea L Ferguson Pharmd, Sarah Ferrell Pharmd, Karen Kovey Pharmd, Joanna Young, Sara Trovinger

Parkview Pharmacy Department

OBJECTIVES: This study aimed to implement a web-based pediatric education program designed for pharmacists who participate in neonatal and pediatric order verification at a community-based health system and to evaluate the success through measuring outcomes related to both comfort and competence of pharmacists in pediatric and neonatal pharmacotherapy.

METHODS: This prospective quality improvement study assessed changes in confidence and competence from before to after education. Eight educational modules were designed to provide education based on the needs of this institution. All pharmacists who participate in neonatal and pediatric order verification were eligible for inclusion throughout the health system. Time in …