Pharmacy and Pharmaceutical Sciences Commons^™

Purdue College Of Pharmacy Experience With Blood Pressure Screenings At The Indiana State Fair, Samuel L. Stukey, Emily B. Vahary, Allison M. Kenneally, Casey J. Bernier, Bruce C. Carlstedt, Jane E. Krause

Purdue Journal of Service-Learning and International Engagement

The objective of this community outreach initiative is to develop and implement a student-led blood pressure screening at the Indiana State Fair in conjunction with the Purdue College of Pharmacy and the Hook’s Drug Store Museum. Under the mentorship of two pharmacy faculty members, third- and fourth-year professional PharmD students and pharmacy fellows hold a nine-hour blood pressure screening at the Indiana State Fair each year. The screening is held at the Hook’s Drug Store Museum and the students and fellows sign-up in teams of 3-4 to host the event. Fair-goers visiting the screening have their blood pressure taken using …

Student Pharmacists Bridging The Gap With Community Partnerships: Purdue University College Of Psychiatric And Neurologic Pharmacists Chapter, Fatima A. Khan, Elise M. Mann

Purdue Journal of Service-Learning and International Engagement

The CPNP Purdue chapter is a student organization that strives to advance mental health awareness and education, reduce stigma, and volunteer in the local community. CPNP Purdue is strengthened by collaboration with partner organizations, including the National Alliance on Mental Illness (NAMI) and Home with Hope, a Lafayette-based recovery housing center. NAMI advocates for effective treatment and education for families affected by mental illness in the surrounding community. Home with Hope provides a continuum of care and environment conducive to recovery following treatment for substance use disorders. These nonprofit partnerships rely heavily upon volunteers, donations, and advocates to provide services …

Complementing The Us Food And Drug Administration Adverse Event Reporting System With Adverse Drug Reaction Reporting From Social Media: Comparative Analysis, Zeyun Zhou, Kyle Emerson Hultgren

Purdue University Libraries Open Access Publishing Fund

Background: Adverse drug reactions (ADRs) can occur any time someone uses a medication. ADRs are systematically tracked and cataloged, with varying degrees of success, in order to better understand their etiology and develop methods of prevention. The US Food and Drug Administration (FDA) has developed the FDA Adverse Event Reporting System (FAERS) for this purpose. FAERS collects information from myriad sources, but the primary reporters have traditionally been medical professionals and pharmacovigilance data from manufacturers. Recent studies suggest that information shared publicly on social media platforms related to medication use could be of benefit in complementing FAERS data in order …

Patterns And Predictors Of Older Adult Medicare Part D Beneficiaries’ Receipt Of Medication Therapy Management, Antoinette B. Coe, Omolola A. Adeoye-Olatunde, Deborah L. Pestka, Margie Snyder, Alan Zillich, Karen B. Farris, Joel F. Farley

Department of Pharmacy Practice Faculty Publications

Background

Medicare Part D medication therapy management (MTM) includes an annual comprehensive medication review (CMR) as a strategy to mitigate suboptimal medication use in older adults.

Objectives

To describe the characteristics of Medicare beneficiaries who were eligible, offered, and received a CMR in 2013 and 2014 and identify potential disparities.

Methods

This nationally representative cross-sectional study used a 20% random sample of Medicare Part A, B, and D data linked with Part D MTM files. A total of 5,487,343 and 5,822,188 continuously enrolled beneficiaries were included in 2013 and 2014, respectively. CMR use was examined among a subset of 620,164 …

Pharmacy Students’ Perspectives On The Initial Implementation Of A Teaching Electronic Medical Record: Results From A Mixed-Methods Assessment, Olga O. Vlashyn, Omolola A. Adeoye-Olatunde, Kimberly S. Illingworth Plake, Jamie L. Woodyard, Zachary A. Weber, Alissa L. Russ-Jara

Department of Pharmacy Practice Faculty Publications

Background
Electronic medical records (EMRs) have been used for nearly three decades. Pharmacists use EMRs on a daily basis, but EMRs have only recently been incorporated into pharmacy education. Some pharmacy programs have implemented teaching electronic medical records (tEMRs), but best practices for incorporating tEMRs into pharmacy education remain unknown. The objectives of this study were to 1) assess pharmacy students’ views and experiences with a tEMR; and 2) identify current learning activities and future priorities for tEMR use in pharmacy education.

Methods
We used a mixed-methods approach, including three, two-hour student focus groups and a 42-item web-based survey to …

Experiences Applying Technology To Overcome Common Challenges In Pharmacy Practice-Based Research In The United States, Stephanie A. Gernant, Omolola A. Adeoye-Olatunde, Matthew M. Murawski, Heather A. Jaynes, Betty A. Chewning, Lyndee M. Knox, Moises Martinez Iii, Jon C. Schommer, Margie E. Snyder

Department of Pharmacy Practice Faculty Publications

Despite the importance of pharmacy practice-based research in generating knowledge that results in better outcomes for patients, health systems and society alike, common challenges to PPBR persist. Herein, we authors describe PPBR challenges our research teams have encountered, and our experiences using technology-driven solutions to overcome such challenges. Notably, limited financial resources reduce the time available for clinicians and researchers to participate in study activities; therefore, resource allocation must be optimized. We authors have also encountered primary data collection challenges due to unique data needs and data access/ownership issues. Moreover, we have experienced a wide geographic dispersion of study practices …

Adolescents’ Perceptions Of Contraception Access Through Pharmacies, Ashley H. Meredith, Emily Vahary, Tracey A. Wilkinson, Carolyn G. Meagher, Thomas Vielott, Mary A. Ott

Department of Pharmacy Practice Faculty Publications

Adolescent pregnancy is an important public health issue, and pharmacist prescribing has the potential to expand contraceptive access and decrease unintended pregnancy. However, little is known about acceptability and uptake of pharmacist prescribing among adolescents, particularly among youth in socially and politically conservative regions of the country. The study objective was to identify how young women in Indiana perceive pharmacist contraceptive prescribing. Participants were recruited from clinics and completed a simulated pharmacist contraception-prescribing encounter; a demographic and behavioral questionnaire; and an in-depth qualitative interview focused on adolescent perspectives on pharmacist prescribing. Data were analyzed using thematic analysis. Sixty young women …

Community Pharmacists’ And Residents’ Decision Making And Unmet Information Needs When Completing Comprehensive Medication Reviews, Kacie L. Mcpherson, Omolola A. Adeoye-Olatunde, Jayna M. Osborne, William R. Doucette, Stephanie A. Gernant, Heather Jaynes, Shobha Phansalkar, Alissa L. Russ-Jara, Margie E. Snyder

Department of Pharmacy Practice Faculty Publications

Objective

To (1) characterize community pharmacists’ and community pharmacy residents’ decision making and unmet information needs when conducting comprehensive medication reviews (CMRs) as part of medication therapy management and (2) explore any differences between community pharmacists and community pharmacy residents in CMR decision making and unmet information needs.

Design

Thirty-to 60-minute semistructured interviews framed using a clinical decision-making model (CDMM) were conducted with community pharmacists and residents.

Setting and participants

Participants were recruited from practice-based research networks and researchers’ professional networks. Eligible participants had completed or supported the completion of at least 2 CMRs in the last 30 days.

Outcome …

Unused Medication Collection: An Emerging Service-Learning Experience For Pharmacy Students, Anne E. Packard, Maryam Noureldin, A. Carmine Colavecchia, Patricia L. Darbishire, Jennifer Colavecchia

Purdue Journal of Service-Learning and International Engagement

While the U.S. makes up around 5% of the world’s population, we consume approximately 75% of the world’s prescription drugs—well over 4 billion prescriptions per year. Approximately one third of those are never used, creating an array of public health challenges. These challenges include land and water pollution; unintentional inappropriate use and unintentional human, pet, and wildlife poisonings; and intentional drug abuse and diversion. Misuse of prescription drugs now exceeds that of all illegal drugs combined. Reducing the number of medications prescribed is of primary importance, as well as collecting unnecessary medications from households and disposing of them through environmentally …

The Role Of The Pharmacy Team In Atrial Fibrillation Detection In Nonclinical Settings, Brian C. Hazelrigg, Monica L. Miller, Sotiris Antoniou, Jagjot Chahal, Sadeer Fhadil

Purdue Journal of Service-Learning and International Engagement

Atrial Fibrillation (AF) is a common cardiac/heart disease that increases a person’s risk of death, making early identification significant in overall disease management. Throughout my time in pharmacy school, I [Brian] have developed an interest in cardiology and research. During my last year of pharmacy school, I spent eight weeks at St. Bartholomew’s Hospital, in London, England, one of the largest cardiac centers within Europe, on an experiential training experience. While there, I had the opportunity to study specifics about many cardiac illnesses, with a focus on atrial fibrillation, and provide education to patients living with this disease. In addition …

Safe Medication Disposal In Underserved Communities, Elaina Etter

Purdue Journal of Service-Learning and International Engagement

Of the 130 Americans who will die each day from opioid overdose, 46 will have overdosed on prescription opioid medications. The opioid epidemic has become one of our nation’s largest public health crises. Because many individuals may have access to prescription medications of family members or friends, responsible medication disposal has become increasingly important to prevent harm.

This fall, I worked on a professional project at local Federally Qualified Health Centers (FQHCs), which aimed to increase education about safe medication disposal. These clinics provide comprehensive healthcare services to underserved patients, many of whom live in rural areas or have limited …

The Role Of Using Formative Assessments In Problem-Based Learning: A Health Sciences Education Perspective, Kristi W. Kelley, Julaine M. Fowlin, Andrew A. Tawfik, Max C. Anderson

Interdisciplinary Journal of Problem-Based Learning

Practitioners in the field of pharmacy are often confronted with ill-structured problems. Specifically, pharmacists are tasked with making patient-specific recommendations that are both safe and effective, which requires combining knowledge from the biomedical, behavioral, and pharmaceutical sciences. Given the dynamic nature of pharmacy as a profession, the field has begun to explore learning strategies that go beyond mere content coverage to strategies that better support higher-order learning outcomes. One of these approaches is problem-based learning (PBL). While studies have focused on how to support PBL to improve learning outcomes, the role of assessment is often overlooked. Further exploration is thus …

Resident Physicians’ Perceptions Of Ambulatory Care Pharmacy, Ashley H. Meredith, Darin Ramsey, Andrew Schmelz, Rachel Berglund

Department of Pharmacy Practice Faculty Publications

Background: Physicians' acceptance of clinical pharmacy services is dependent on exposure to those services, with use increasing as resident physicians progress through their training. Resident physicians train within environments that have a multidisciplinary teaching and clinical care approach, working closely with other healthcare professionals. Ambulatory care pharmacists are increasingly working with resident physicians in clinic settings as part of the multidisciplinary team, and identification of resident physicians’ perceptions may influence future collaboration.

Objective: The objective of this research is to evaluate the perception of ambulatory care clinical pharmacy services from the perspective of resident physicians.

Methods: A statewide network of …

Development Of An Imaging Analysis Algorithm For Fluorescence-Based High Content Screening In Parkinson’S Disease, Ryan Arlinghaus

The Journal of Purdue Undergraduate Research

No abstract provided.

A Pharmacological Model Of Trpa1-Mediated Nociception In Zebrafish For Therapeutic Discovery, Emre Coskun

The Journal of Purdue Undergraduate Research

No abstract provided.

Amorphous Solid Dispersion Formation Via Solvent Granulation – A Case Study With Ritonavir And Lopinavir, Niraj S. Tirasi, Sonal Bhujbal, Qi Tony Zhou, Lynne Taylor

Department of Industrial and Physical Pharmacy Faculty Publications

Herein, we evaluate the potential of using a simple solvent granulation process to prepare a binary drug amorphous solid dispersion (ASD) containing two anti-HIV drugs, ritonavir and lopinavir. The drugs were granulated onto a mixture of lactose and microcrystalline cellulose, followed by drying to remove the solvent. The resultant granules were characterized and each drug was found to be X-ray amorphous. No crystallization was observed following storage for 1 month under accelerated stability conditions (40 °C and 75% relative humidity). The dissolution behavior of the compacted granules was compared with the marketed formulation. The dissolution rate of ritonavir was found …

Alerts For Community Pharmacist-Provided Medication Therapy Management: Recommendations From A Heuristic Evaluation, Margie E. Snyder, Heather A. Jaynes, Stephanie A. Gernant, Julie Diiulio, Laura G. Militello, William R. Doucette, Omolola A. Adeoye-Olatunde, Alissa L. Russ

Department of Pharmacy Practice Faculty Publications

Background
Medication therapy management (MTM) is a service, most commonly provided by pharmacists, intended to identify and resolve medication therapy problems (MTPs) to enhance patient care. MTM is typically documented by the community pharmacist in an MTM vendor’s web-based platform. These platforms often include integrated alerts to assist the pharmacist with assessing MTPs. In order to maximize the usability and usefulness of alerts to the end users (e.g., community pharmacists), MTM alert design should follow principles from human factors science. Therefore, the objectives of this study were to 1) evaluate the extent to which alerts for community pharmacist-delivered MTM align …

A Comparison Of Student Pharmacist Clinical Interventions During An Internal Medicine Advanced Pharmacy Practice Experience (Appe) In A High-Income Versus Low-Income Setting, Ellen Schellhase, Monica Miller, Shelby Wilkinson, Rakhi Karwa

Engagement & Service-Learning Summit

Objectives: Compare and contrast the number and type of interventions made by student pharmacists who participated in an adult internal medicine APPE in the US to an internal medicine APPE in Kenya.

Methods: A US-based faculty-led, four-week internal medicine APPE with interprofessional team rounding that provides care for underserved patients in an urban setting and hosts 16 students annually was compared to a faculty-led, eight-week internal medicine APPE in Kenya that hosts on average 24 students annually. Starting May 2017 – January 2018 a standard clinical intervention collection form was used by all students on these two APPEs starting …

The Pharmaceutical Industry: A Pharmacy Student's Guide, Christian Egly, Yaman Kaakeh

Purdue Journal of Service-Learning and International Engagement

Christian Egly is a fourth-year (P4) pharmacy student in the Purdue University College of Pharmacy. During his years at Purdue, he worked in labs performing bench research in clinical pharmacology and biochemistry. He plans to work in the pharmaceutical industry after graduation. During his fourth year, he completed rotations in business development at Kashiv Pharma, LLC, and was hired there for an internship in 2017. In the article, Christian describes his personal experiences at Kashiv Pharma, LLC, and how industry can positively affect patient communities.

Peer Health Educators On Campus: Teaching Safe Medication Practices, Baylee Q. Bryan, Olga O. Vlashyn, Stephanie A. Deremiah, Murphy K. O'Toole, Katherine M. Joseph, Jane E. Krause

Purdue Journal of Service-Learning and International Engagement

Baylee Q. Bryan, Olga O. Vlashyn, Stephanie A. Deremiah, and Murphy K. O’Toole are advanced professional students in the Doctor of Pharmacy program at Purdue University, graduating in May 2019. Katherine M. Joseph is a senior in the School of Nursing, graduating in December 2018. Jane E. Krause (Clinical Associate Professor of Pharmacy Practice, Purdue College of Pharmacy) served as a faculty mentor for this project. In this article, the authors describe their service-learning project intended to increase awareness on campus regarding prescription drug abuse and misuse.

Leveraging Technology: Enhancing Study Time Through Competition, Ming Yang, Lindsey Eble, Patricia Darbishire

Purdue Journal of Service-Learning and International Engagement

Ming (Max) Yang and Lindsey Eble are students in their final year of the Doctor of Pharmacy program in the Purdue University College of Pharmacy. Max is originally from Chesterfield, Missouri, and Lindsey is from Newburgh, Indiana. After graduation in May 2018, Max will complete residency training at Aurora St. Luke’s Medical Center in Milwaukee, Wisconsin. Lindsey will complete residency training at Barnes-Jewish Hospital in St. Louis, Missouri. Both plan to work in a hospital or clinic setting providing patient care within an interdisciplinary healthcare team. They both worked under the guidance of Dr. Patricia Darbishire to develop a website …

Indiana University Health: A Student, An Institution, And The People, Allison Bates

Purdue Journal of Service-Learning and International Engagement

Allison Bates is a student in Purdue University’s Doctor of Pharmacy program with an anticipated graduation date of May 2019. Her future career aspirations are to practice in ambulatory care pharmacy or in an oncology setting. She has volunteered with the Joseph Maley Foundation since 2009 and with the “It’s My Closet” organization in Lafayette since 2014. This article describes her experience working as an intern with Dr. Dawn Moore, Vice President of Pharmacy and Chief Pharmacy Officer at IU Health.

Value-Added Services: Incorporating Pharmacy Students In A Hospital Setting, Megan Unger

Purdue Journal of Service-Learning and International Engagement

Megan Unger, a PharmD candidate in her fourth professional year in the College of Pharmacy, completed an introductory pharmacy practice experience at Deaconess Hospital in Evansville, Indiana, during her third professional year. This was the third of thirteen experiential learning rotations that she will complete prior to graduation in 2019. Her future plans include pursuing a postgraduate residency training program. In this article, Megan highlights the value-added services that pharmacy students can provide to institutional pharmacy settings and the patients served.

Targeting Neuropeptides To Bone Fractures For Accelerated Healing, Nicholas A. Young, Jeffery J. Nielsen, Philip S. Low

The Summer Undergraduate Research Fellowship (SURF) Symposium

In patients over the age of 65 especially, bone fractures represent a significant disease burden. Non-invasive drug therapies are not available for bone fractures which represents a problem for this population. Vasoactive intestinal peptide (VIP) and Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP), two neuromodulator peptides in the glucagon superfamily, have demonstrated positive regulation of osteoblast proliferation and activity. Using acidic oligopeptides, we have developed ligands that target to and accumulate at fracture sites. These targeting ligands can be synthesized in sequence with bone anabolic peptides to minimize off target effects and increase potency at the fracture site to create safer and …

What Predicts Medication Therapy Management Completion Rates? The Role Of Community Pharmacy Staff Characteristics And Beliefs About Medication Therapy Management, Omolola A. Adeoye-Olatunde, Leslie M. Lake, Spencer G. Lourens, Rachel E. Morris, Margie E. Snyder

Department of Pharmacy Practice Faculty Publications

Objectives: To model the association between pharmacy technicians' attitudes and planned behaviors toward participating in medication therapy management (MTM) and MTM completion rates. Secondary objectives included 1) to compare pharmacy technician and pharmacist attitudes and planned behaviors toward participating in MTM and 2) to identify respondent and pharmacy demographic factors associated with MTM completion rates.

Design: A 27-item survey, adapted from a previously published survey tool based on the Theory of Planned Behavior (TPB), was used to collect respondent perceptions of MTM. Study procedures were approved by the institutional review board.

Setting and participants: Pharmacy technicians and pharmacists representing 116 …

Preparation And Characterization Of Multimodal Hybrid Organic And Inorganic Nanocrystals Of Camptothecin And Gold, Christin P. Hollis, Alan K. Dozier, Barbara L. Knutson, Tonglei Li

Department of Industrial and Physical Pharmacy Faculty Publications

We demonstrate a novel inorganic-organic crystalline nanoconstruct, where gold atoms were imbedded in the crystal lattices as defects of camptothecin nanocrystals, suggesting its potential use as simultaneous agents for cancer therapy and bioimaging. The incorporation of gold, a potential computed tomography (CT) contrast agent, in the nanocrystals of camptothecin was detected by transmission electron microscope (TEM) and further quantified by energy dispersive X-ray spectrometry (EDS) and inductively coupled plasma-optical emission spectrometers (ICP-OES). Due to gold's high attenuation coefficient, only a relatively small amount needs to be present in order to create a good noise-to-contrast ratio in CT imaging. The imbedded …

Pharmacy Practice And Research: The Development Of A University Collaboration In Colombia, Ellen Schellhase

Engagement & Service-Learning Summit

No abstract provided.

Safety And Service-Learning: Engaging Pharmacy Students To Make Safer Communities, Patricia Darbishire, Chelsea Anderson

Engagement & Service-Learning Summit

Poster Abstract

Objective:

To evaluate student perceptions of a service-learning experience for potential implementation in the curriculum.

Method:

A new 3-week intensive elective course was piloted in the Spring of 2017 at Purdue University College of Pharmacy. Seven third professional year students were included in the pilot and were divided into three groups. Each group of 2-3 students was assigned to one of 3 predetermined community partner sites. Students were taught how to perform a needs assessment and then designed a project targeted to improve safety at their site. Students completed a pre-post questionnaire that assessed their perceptions of the …

Expansion Of Pharmacy Students’ Involvement In Global Health And International Clinical Rotations, Alice C. Chang, Monica L. Miller, Ellen M. Schellhase

Engagement & Service-Learning Summit

No abstract provided.

Student Pharmacists And Street Children: A Mutually Beneficial Relationship, Mario A. Hoyos, Monica L. Miller, Ellen M. Schellhase, C. Ryan Tomlin, Sonak Pastakia, Samuel Kimani, Tim Mercer

Purdue Journal of Service-Learning and International Engagement

The Tumaini Children’s Drop-In Center is a daytime drop-in center for the street children of Eldoret, Kenya. It is part of a partnership between the Purdue University College of Pharmacy, the Academic Model Providing Access to Healthcare program, Eldoret community members, and numerous individuals in both Kenya and the US. Through the efforts of local staff and Purdue student pharmacists, who work at the local hospital on an eight-week clinical rotation, the center has helped a population of nearly 400 local street children by providing a safe haven from life on the streets. Purdue student pharmacists aid the center by …