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Full-Text Articles in Pharmacy and Pharmaceutical Sciences

Genome-Wide Mutagenesis To Investigate The N-Terminal Methylome: The Protective Effects Of Hsp31 And Other Methylated Proteins In Yeast, James Rooney, Jacob Lindsey Jan 2024

Genome-Wide Mutagenesis To Investigate The N-Terminal Methylome: The Protective Effects Of Hsp31 And Other Methylated Proteins In Yeast, James Rooney, Jacob Lindsey

The Journal of Purdue Undergraduate Research

The purpose of this study was to understand the role of methylation in regulating the cellular stress response of Hsp31 in Saccharomyces cerevisiae yeast cells. Hsp31 is known to be methylated by the N-terminal methyltransferase Tae1. Changing the methylation site can affect the methylation status of Hsp31, which may play a role in the protective activity of Hsp31 against cellular stress. GLO1 is a gene in yeast involved in catalyzing the detoxification of methylglyoxal (MGO), which is a by-product of glycolysis. We established that S. cerevisiae in the glo1Δ and background is sensitive to cellular stress by MGO. Mutant strains …


The Effect Of Fatty Acid Synthase (Fasn) Depletion In Pulmonary Metastatic Formation In Breast Cancer Murine Models, Zilin Xianyu Nov 2022

The Effect Of Fatty Acid Synthase (Fasn) Depletion In Pulmonary Metastatic Formation In Breast Cancer Murine Models, Zilin Xianyu

The Journal of Purdue Undergraduate Research

No abstract provided.


Assessing Availability And Effectiveness Of Pharmacy Spanish Interpreter Services: A Systematic Review, Ma. Emmanuelle R. Domingo Nov 2022

Assessing Availability And Effectiveness Of Pharmacy Spanish Interpreter Services: A Systematic Review, Ma. Emmanuelle R. Domingo

The Journal of Purdue Undergraduate Research

No abstract provided.


Development Of An Imaging Analysis Algorithm For Fluorescence-Based High Content Screening In Parkinson’S Disease, Ryan Arlinghaus Aug 2019

Development Of An Imaging Analysis Algorithm For Fluorescence-Based High Content Screening In Parkinson’S Disease, Ryan Arlinghaus

The Journal of Purdue Undergraduate Research

No abstract provided.


A Pharmacological Model Of Trpa1-Mediated Nociception In Zebrafish For Therapeutic Discovery, Emre Coskun Aug 2019

A Pharmacological Model Of Trpa1-Mediated Nociception In Zebrafish For Therapeutic Discovery, Emre Coskun

The Journal of Purdue Undergraduate Research

No abstract provided.