Pharmacy and Pharmaceutical Sciences Commons^™

Cost Variation Analysis Of Oral Hypoglycemic Drugs In The Egyptian Market, George G. Abdelmessih, Aya M. Abdelmagid, Samar F. Farid

Bulletin of Faculty of Pharmacy Cairo University

Introduction: Type II diabetes mellitus is a lifelong condition requiring lifelong medication. This study aims to analyze the cost variation of the oral hypoglycemic drugs in the Egyptian pharmaceutical market.

Methodology: Egyptian drug database of the Egyptian Drug Authority was used to get the official prices of drugs in the Egyptian pharmaceutical market analyzed in this study. The cost ratio and the percentage cost variation were calculated. The price was documented using unit dose of 1 tablet per EGP.

Results: Out of 15 oral hypoglycemic drugs in the Egyptian market at closing 2022 (9 monotherapy and 6 combination therapy) of …

Colistin And Antimicrobial Resistance Among Gram-Negative Bacteria Isolated From Poultry In West Bank, Palestine, Mohammad Qadi, Rasha Khayyat, Safaa Alhato, Abdelraouf A. Elmanama, Ashraf R. Zayed, Muna M. Abbas, Maysa Daqqa, Faizeh Hussein, Ahmed Mousa

Palestinian Medical and Pharmaceutical Journal

Background: The escalating incidence of antimicrobial resistance in Gram-negative bacteria has elicited worldwide apprehension owing to its profound ramifications, such as the emergence of infections that cannot be effectively treated and may result in mortality. The poultry industry is of significant concern due to its substantial utilization of antimicrobials, including those regarded as last-resort therapies for complex multi-drug resistant Gram-negative infections. Methods: A comprehensive collection of ninety cloacal swabs was undertaken from a diverse range of thirty poultry farms located within the Nablus governorate during the period spanning from March to June in the year 2019. The swabs, specifically collected …

Dereplication Study And Pharmacological Potentials Of Phytochemical Constituents Of Nigerian Propolis From Umudike, Sylvester N. Ugariogu, Stephanie A. Ezirim, Ijeoma A. Duru, Samya S. Alenezi, Anyam John V., Igoli John O.

Palestinian Medical and Pharmaceutical Journal

Liquid chromatography-mass spectroscopy (LC-MS) was used to detect the phytochemicals present in the extracts of propolis from Umudike. The dereplication study of the hexane and ethyl acetate extracts of green, brown and red propolis samples from a hive in Umudike Umuahia Nigeria were studied using MestReNova software. About 31 compounds previously reported from Africa propolis were detected. The results revealed the presence of 23compounds were found in the ethyl acetate extract of the brown propolis, while 20 were detected in both the ethyl acetate extract of the green and red propolis. The hexane extract of the brown propolis showed 20 …

Antioxidative And Antidiabetic Investigations Of The Aqueous Extract Of Pelargonium Graveolens Grown In Palestine, Belal Rahhal, Maysa`A Radwan, Yasmeen Edili

Palestinian Medical and Pharmaceutical Journal

Plants have been used for many healing aims since outdated times, and to this day, many essential pharmaceutical dosage forms originated from herbal products. The utilization of herbal products recognized by therapeutic agents in modern healthcare systems has increased over the past two decades. The present biological screening study employed reference methods to estimate Pelargonium graveolens four extracts from the Nablus governorate in Palestine. The outcomes affirmed that the four extracts of the P. graveolens plant have potent antioxidant activity compared with Trolox. The aqueous extract has very potent activity, followed by acetone extract in comparison with Trolox (((s)-(-)-6 …

A Bibliometric Analysis Of Cannabis-Related Research From 2010 To 2022, Chaimae Haboubi, Yahya El Hammoudani, Nidal Jaradat, Shehde Jodeh, Khadija Haboubi, Fouad Dimane

Palestinian Medical and Pharmaceutical Journal

Cannabis plant cultivation was prohibited for a period, but in recent times, there has been a shift in its perception. It is now being researched extensively to identify the best methods for its utilization. This article provides a bibliometric review of studies related to cannabis. Bibliometric analysis is a widely used technique for analyzing large volumes of scientific data. For this study, 3,761 documents were collected from the popular Scopus database, published between 2010 and 2022. The collected data was analyzed using the "Bibliometrics" package in the R programming language. "Biblioshiny" and "Vosviewer" were employed to visualize the results. The …

Menopausal Symptoms And Quality Of Life Among Palestinian Women: A Cross-Sectional Study, Souad Belkebir, Lubna Saudi, Balqees Nassar, Noor Nabresi, Mohammad Abuawad

Palestinian Medical and Pharmaceutical Journal

Background: Natural menopause is associated with somatic, vasomotor, psychological, and sexual complaints that may affect women's quality of life (QOL). Aims: To determine the prevalence and severity of menopausal symptoms and their impact on QoL among Palestinian women visiting primary care centers. Methods: A cross-sectional study was conducted from November 2018 through March 2019. Convenience sampling was used to interview 380 women aged 45–60 years attending primary care centers in the West Bank city of Nablus. The Menopause Rating Scale (MRS) assessed the prevalence and severity of menopausal symptoms and QoL. Mean scores of menopausal categories were compared for different …

Synthesis, Characterization, Molecular Docking, And Preliminary Antimicrobial Evaluation Of Thiazolidinone Derivatives, Sarmad S. Hussein, Karima F. Ali, Fouad A. Al-Saady

Palestinian Medical and Pharmaceutical Journal

Several derivatives carrying thiazolidine-4-one pharmacophore were prepared to evaluate their antimicrobial activities. The set of compounds were shown to possess potential activities as determined by molecular docking studies for both candidal (14-alpha demethylase) and bacterial enzymes (Penicillin binding protein of E. coli). In vitro antimicrobial activities were also performed to confirm the molecular docking results. Molecular characterization by spectral techniques (FT-IR, ¹³C NMR and ¹H NMR) was carried out to confirm the identity of the synthesized compounds. The synthesized compounds were evaluated for antibacterial and anticandidal activity by comparing them with the reference drugs (positive controls) ceftriaxone …

Perception And Factors Associated With Patient Safety Culture In An Academic University Hospital In Palestine, Loai M. Zabin

Palestinian Medical and Pharmaceutical Journal

Background: Patient safety culture plays a pivotal role in enhancing care quality, preventing errors, promoting clinical outcomes, and reducing healthcare costs. It also helps minimize adverse events, increasing patient safety, and elevating the quality of medical care provided. This study aims to evaluate the perception of patient safety culture within a university hospital. It aims to examine the correlation between the demographic and workplace characteristics of the staff and their perceptions of patient safety culture. Methods: A quantitative cross-sectional study design was employed for this study. The Arabic version of the Hospital Survey of Patient Safety Culture (HSOPSC) v2.0 was …

Molecular And Physicochemical Studies Of Mrsa Resistant To Antibiotics: A Known Beyond, Himanshu Bhogekar, Ritesh P. Bhole, Pramod B. Khedekar, Rupesh V. Chikhale

Palestinian Medical and Pharmaceutical Journal

As we see in the community, environment, and daily life, bacterial, microbial, and viral infection creates the severe problem. The medical field is continuously worried about the treatment of infections caused by the microorganism. Day by day, the microorganism in nature becomes stronger and gains more susceptibility to major infections. The researcher continuously works on the development of new antibiotic to break infectivity of the microorganism. But bacteria have the characteristic to adapt in a new environment by generating resistance. Many antibiotics since the discovery of penicillin work on the effects of bacteria for a short duration of time, and …

Update On The Efficacy Of Aerosol Therapy Delivered To Obstructive Lung Disease Patients, Mohammed A. Amin, Hasanain Kamil Hasan, Hebatullah K. Taha, Raghda R.S. Hussein, Mohamed E.A. Abdelrahim

Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences

The distribution of many medications to the body via the respiratory tract system is crucial. This route has emerged as one of the most crucial techniques for the delivery of locally acting medications that can be used to treat a variety of respiratory conditions, including asthma and chronic obstructive pulmonary disease (COPD). The advantages of this focused drug delivery to the lungs over systemic administration methods include an improved therapeutic effect, a faster onset of action, and fewer systemic side effects.

Many formulations as suspension and solutions, such as bronchodilators, corticosteroids, and antibiotics have been recommended in a wide area …

A Study Of Serum Levels Of Ferritin, Hepatic And Renal Functions In Beta-Thalassemia Major (Btm) Patients Treated With Deferasirox (Dfx) Tablets, Desferioxamine (Dfo) Vial, Or Combination Of Both (Dfx + Dfo) In Thalassemia Center/Karbala, Shereen M. Mekkey, Maysam Ali Ameen, Najwa Kahtan Hadi

Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences

A category of inherited blood illnesses known as beta-thalassemias are defined by abnormalities in the synthesis of hemoglobin beta chains, which can result in a wide range of phenotypes, from severe anemia to people who show no symptoms at all. People who have thalassemia major typically experience severe anemia during the first two years of life, necessitating frequent red blood cell (RBC) transfusions.

Management of individuals with β-thalassemia is centered on appropriate, safe blood transfusions (free of transfusion-transmitted illnesses) and prevention of iron excess. Complications from iron overload are brought on by routine transfusion therapy.

This study is a retrospective …

Greenness Assessment And Development Of An Innovative Hplc Method For The Determination Of Rifaximin And Sodium Benzoate In Oral Suspension, Hani M. Hafez, Naser F. Al-Tannak, Mohamed A. Rabeh

Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences

The pharmaceutical industry has brought advancement and opportunities. However, it has also presented challenges and complexity that must be addressed. The pharmaceutical industry aims to protect public health by providing economical, effective, safe, and appropriate treatments. The analytical method monitors medication concentrations to ensure efficacy and safety. Chemical preservations protect drugs from microbes until administration. In Refax suspensions, the concentration of rifaximin (Antibacterial, API) and sodium benzoate (chemical preservative) must be determined to ensure the suspension's effectiveness, stability, and safety with regulatory standards.

An innovative HPLC method was created to monitor the concentrations of rifaximin (Antibacterial, API) and sodium benzoate …

Assessing Pharmacy Students' Knowledge And Awareness Regarding The Rational Utilization Of Antibiotics And The Issue Of Antimicrobial Resistance In Iraq, Hasanain Kamil Hasan, Mohamed Mahmoud Abdelrahman, Ali A. R. Aldallal, Hayder Ridha Salman, Montadher Mohammad Majeed, Mohammad Jabbar Hassan, Alaa Shukry Mtasher, Ahmed Majid Ibrahim

Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences

Introduction: The Non rational use and overall volume of antibiotic consumption in the community is one of the foremost causes of antimicrobial resistance. In developing countries like Iraq, pharmacists often dispense ‘prescription-only’ drugs, like antibiotics, to patients who do not have a prescription. The objectives of this study are to estimate the prevalence of irrational use of antibiotics bought from pharmacies and other medication outlets in some areas in Iraq, as well as to investigate the factors related with such usage.

Method: The cross-sectional face to face survey was conducted in AL Mustaqbal University, were 267 students at College of …

Development Of A Multi-Target Pharmacophore-Based Virtual Screening Agent Against Covid-19, Nashwa A. Ibrahim, Ahmed M. Gouda, Hany A. M. El-Sherief

Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences

The worldwide outbreak of the COVID-19 pandemic compelled scientists to develop new, highly effective therapeutic approaches to fight it. Multitarget drugs have been proven to be effective in managing complex disorders. But designing multitarget drugs is a great challenge. In this study, to prevent a lack of efficacy due to viral mutation escape, a multi-target agent against the COVID-19 virus was discovered. As crucial targets, RNA-dependent RNA polymerase (RdRp), COVID-19 main protease (Mpro), and SARS-CoV-2 Nsp15 were selected. A pharmacophore model was developed using the native ligands of the chosen targets. This model was used to screen the ZINC Drug …

A Cross – Sectional Observational Study On Pharmacoeconomics Burden Of Covid -19 In Ashmoun Fever Hospital Delta Egypt, Marwa Helmi Desouki, Marwa G. Elhennawy, Samar F. Farid

Bulletin of Faculty of Pharmacy Cairo University

Background: A wide range of respiratory illnesses like common colds, Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS) are caused by coronaviruses.

In 2019 scientists in Wuhan, China discovered a new coronavirus (COVID-19). Unknown new coronavirus that infected people for the first time and causes losses for humans. It has caused a large number of deaths around the world and a greater number of injuries, and the countries of the world began to take measures and closures to confront the spread of this virus, and the economy was greatly affected.

Aim of Study: This study provides …

Assessing Health Needs In A Dominican Republic Community During An Interprofessional Service-Learning Trip, Gabriela Andonie, Hanna Rotundo, Ashanti Jones, Logan Dugas, Shylon Francis

Journal of Interprofessional Practice and Collaboration

Purpose: International medical missions may increase access to medicines and care, but international teams must understand local needs to implement appropriate services. In 2023, a multidisciplinary team from our institution partnered with a nonprofit organization in the barrio of Cienfuegos, Dominican Republic with the goal of strengthening local health services. The primary objective of this study was to identify health-related needs in Cienfuegos from the perspective of community members and local health care workers.

Methods: A qualitative study was conducted as part of a service-learning initiative. After obtaining informed consent, the investigators conducted individual semi-structured interviews facilitated by multi-lingual interpreters. …

Concept Analysis: Undergraduate Nursing Student Clinical Performance Anxiety, Maria Gros

Journal of Interprofessional Practice and Collaboration

Concept Analysis: Undergraduate Nursing Student Clinical Performance Anxiety

Maria Gros, MSN, RN, CEN

Department of Nursing, Nicholls State University

Correspondence to: Maria Gros, MSN, RN, CEN. Department of Nursing, Nicholls State University, 906 East 1^st Street, Thibodaux, Louisiana, 70301. Phone: 985-448-4730. Email: maria.gros@nicholls.edu

Article type: Original article written in a doctoral course in the Doctorate in Nursing Education at University of West Georgia

Word count: 3023 words

Abstract

Purpose: This paper defines and clarifies clinical performance anxiety (CPA) as it pertains to undergraduate nursing students in the clinical setting. This research also identifies how CPA can be detrimental to …

Phytochemical Assay And In – Vitro Cytotoxicity Assessment Of Cassava Peel (Manihot Esculenta) From Ethanol And Ethyl Acetate Extract Against Cervical Cancer Cells (Hela), Alice Hari Soejono, Surya Dwira, Puji Sari

Indonesian Journal of Medical Chemistry and Bioinformatics

Introduction: Cervical cancer is a type of cancer that develops in a woman’s cervix. It is a result of HPV (Human Papilloma Virus) and is one of the deadliest types of cancer. Some cervical cancer management including chemotherapy, which until recently continues to develop to cure the condition, is relatively expensive and comes with multiple different side effects.

Method: Manihot esculenta undergoes multilevel maceration with the solvent of ethanol and ethyl acetate. This leads to the formation of ethanol extract and ethyl acetate extract of Manihot esculenta that is analyzed through phytochemical assay and thin layer chromatography (TLC) to determine …

Knowledge And Attitude Of Lebanese Adults Towards Asthma In Beirut, Lebanon, Farah Hatem Haidar, Doaa Issa, Maha Aboul Ela, Karim Raafat

BAU Journal - Health and Wellbeing

Asthma, a serious global health problem, has been an area of interest due to its increasing prevalence, expanding treatment costs, and rising burden on patients and the community. Since asthma cannot be cured, clinical episodes can be prevented and controlled by adequate management and sufficient knowledge of the disease. Appropriate treatment may relieve asthma symptoms and improve quality of life. However, poor knowledge of asthma disease and medication use, misdiagnoses, misuse of inhalers and inadequate self-management of disease symptoms may have a greater impact on the disease process. Therefore, assessment of the population’s knowledge and attitude toward asthma is essential. …

Basic Structure Of The Pharmacophore Virtual Screening Protein 7kg7 For Candidate Therapeutic Options Covid-19, Ahmad Ridha Al Fiqri

Indonesian Journal of Medical Chemistry and Bioinformatics

Coronavirus disease (COVID-19) caused by severe acute respiratory syndrome, namely coronaviruses (SARS-CoV-2) has been a pandemic to date and is contagious with relatively high mortality rates. Various efforts have been made to control the pandemic to finding the best solution to reduce the spread such as rapid detection based on molecular and serological, as well as efforts to find the best medicine for COVID-19 patients continue to be carried out. We analyzed and concluded that the presatovir compound is capable of being a substitute for the native protein ligand 7KG7, this is proved with a ΔG value of -13.22 kcal/mol …

Antioxidant Activities And Protective Effects Of Shorea Macrophylla Leaf And Bark Extracts, Salfarina Ramli, Nik Nor Sabrina Sukri, Nur Adhwa’ Faqihah Zulkifli, Donna Maretta Ariestanti, Chee Yan Choo, Hasseri Halim, Nurhuda Manshoor, Richard Johari James

Pharmaceutical Sciences and Research

Shorea macrophylla, also known as the ‘Engkabang’ tree or Light Red Meranti, is renowned for its role in reforestation efforts. Despite lacking records of traditional use, the reported biological activities of other species within the Shorea genus spark curiosity about the potential biological activities of this plant. Therefore, this study aims to explore the antioxidant capabilities of S. macrophylla leaf and bark extracts, along with their protective effects against oxidative stress using a brine shrimp model. In the evaluation of antioxidant potential, 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) assays were employed. Extracts were incubated in …

A New Approach To Balance Dental Fear And Anxiety By Using Bachtm Flower Therapy, Irina Maria Gheorghiu, Alexandru Andrei Iliescu, Stana Paunica, Marina Giurgiu, Brandusa Mocanu, George Alexandru Popescu, Anca Silvia Dumitriu

Journal of Mind and Medical Sciences

Treatments in dentistry currently consist of an interdisciplinary approach, including (but not necessarily limited to) the holistic perspective. The different fields of allopathic and complementary medicine are used together to ensure not only a high-quality restorative treatment, but also to provide patients with psychological and emotional support. This perspective also applies to dental anxiety, which consists of complex (emotional, vegetative and psychomotor) manifestations. One of the most well-known complementary therapies for reducing dental fear and anxiety is BachTM Flower Therapy. Even if the mechanism of action of this therapy is not yet scientifically documented, notable results have been and continue …

Management Of Keloid-Associated Pruritus With Topical Crisaborole 2% Ointment: A Case Report, Daniel A. Nguyen, Elizabeth Thai Ms, Stephen E. Weis

HCA Healthcare Journal of Medicine

Introduction

The pathophysiology of keloid formation is poorly understood, and current treatments, including intralesional corticosteroids, cryotherapy, and surgery, are often associated with high resistance to treatment and recurrence. The multifactorial pathogenesis of keloid formation suggests that aberrant inflammatory cytokine signaling associated with keratinocyte dysregulation may contribute to keloid-associated pruritus.

Case Presentation

In this paper, we report 2 cases of keloid-associated pruritus that were successfully treated with topical crisaborole 2% ointment, a phosphodiesterase 4 (PDE4) inhibitor. Both patients had previously undergone multiple unsuccessful treatments before being treated with crisaborole 2% ointment. In both cases, the patients experienced complete relief of pruritus …

Barriers And Facilitators Of Pharmacists’ Roles During The Pandemic In Malaysia, Thanushiri Palani Velu, Farida Islahudin, Wei Wen Chong

Makara Journal of Health Research

Background: The coronavirus disease 2019 (COVID-19) left a devastating impact on healthcare systems worldwide. The crisis initially emerged as a supply disruption issue but eventually evolved into a myriad of additional challenges, which were attributed mainly to the extensive scale of the pandemic. This study aimed to explore the barriers to the role of hospital pharmacists and related facilitators encountered during the COVID-19 pandemic.

Methods: Pharmacists in Malaysia participated in a cross-sectional online questionnaire-based survey. The participants were recruited using convenient sampling. Cronbach alpha of the questionnaire was analyzed.

Results: The study successfully enrolled 367 pharmacists. The …

Current Update Of Clinical Therapeutic Strategies For Colon-Targeted Delivery Systems, Risa Widiani Batubara, Fadlina Chany Saputri, Raditya Iswandana

Pharmaceutical Sciences and Research

Oral colon-targeted drug delivery systems represent a significant advancement offering both systemic and local therapeutic effects for a range of intestinal diseases, including irritable bowel syndrome, inflammatory bowel disease, colonic bacterial infections, and colorectal cancer. These systems facilitate the delivery of both small molecules and macromolecular compounds such as peptides, proteins, antibodies, oligonucleotides, RNA, and probiotics. This review provides an up-to-date exploration of the critical factors crucial for the effective design and development of drug delivery systems targeting the colon. The chosen strategy takes into account various aspects of colon physiology that influences the profile of drug release, absorption, dissolution, …

Transdermal Delivery Of Ketoprofen For Osteoarthritis Treatment And Management: A Literature Review On Current Progression, Dwi Asih Ramadhani, Yahdiana Harahap, Erny Sagita, Kartika Citra Dewi Permata Sari, Rr. Kirana Andranilla, Jessica Trisina, Gabriella Frederika Punu, Delly Ramadon

Pharmaceutical Sciences and Research

Arthritis, a diverse spectrum of joint disorders, is characterized by chronic pain and inflammation. Osteoarthritis (OA), the most prevalent form, leads to disabling pain, functional limitations, and reduced mobility. Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for managing OA pain, with ketoprofen recognized as one of the effective options. However, oral administration of ketoprofen may cause gastrointestinal irritation. Addressing this issue, Transdermal Drug Delivery Systems (TDDS) emerge as a promising alternative route of administration. TDDS facilitates delivery of various drugs through the skin without undergoing first-pass metabolism. Recent studies have centered on enhancing ketoprofen’s transdermal delivery, particularly focusing on different …

Antioxidant, Tyrosinase Inhibition Activity, And In Vitro Spf Evaluation Of Pepino Fruit Extract (Solanum Muricatum Aiton) In Different Solvent Types And Concentrations, Nining Sugihartini, Girly Risma Firsty, Wahyu Kumil Laila, Sri Mulyaningsih, Ichwan Ridwan Rais

Pharmaceutical Sciences and Research

Solvent is a key factor that affects the effectiveness of active compound extraction from plant materials (simplisia). This study aimed to determine the optimal type and concentration of solvent used in the extraction of pepino fruit based on the parameter of antioxidant and tyrosinase inhibition activity, as well as Sun Protection Factor (SPF) value. The extraction was carried out using the maceration method with ethanol or ethyl acetate as the solvent, each at concentrations of 50%, 70%, and 96%, respectively. The antioxidant activity of the extracts was evaluated using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) method. The inhibition of tyrosinase and …

Beyond Mitragynine: Composition Survey And Stability Assessment Of Kratom Tea Ordered Via Food Delivery Platforms In Bangkok, Thailand, Yuta Tokuda, Apinya Tubtimrattana, Nat Tansrisawad, Kornvalee Meesilpavikkai, Parath Thirati

Chulalongkorn Medical Journal

Background: Kratom is a native tree to Southeast Asia. Kratom leaves have long been used medicinally and recreationally due to their stimulative and opioid-like effects attributed to high endogenous levels of mitragynine and related alkaloids. Kratom is widely consumed as tea and is now publicly sold, including on food delivery platforms, after recent decriminalization despite selling of kratom products being still considered illegal by other acts.

Objectives: To assess the formulas of kratom teas sold on Thai food delivery platform together with their consistency and the stability of refrigerated teas.

Methods: Kratom alkaloids, mitragynine and 7-hydroxymitragynine, and additive contents of …

Smart Spectrophotometric Approaches For Estimation Of Difluprednate In Existence Of Its Synthetic Precursor And Alkaline Degradation Product; Comparative Statistical Studies And Analytical Ecological Appraisal, Heidi R. Abd El-Hadi, Basma M. Eltanany, Hala E. Zaazaa, Maya S. Eissa

Bulletin of Faculty of Pharmacy Cairo University

Scientists are currently attempting to lessen the harmful effects that chemicals and solvents have on the environment. The current work suggests four sensitive and sustainable spectrophotometric techniques for quantifying difluprednate (DIF) in presence of hydrocortisone acetate, which is a synthetic precursor of DIF, and in the presence of DIF alkaline degradation product. These methods are dual wavelength, fourier self-deconvolution, first derivative, and double divisor derivative ratio. The linearity range for all methods was 15.00-40.00 µg/mL. There is no statistically significant difference between established and reported methods, and the suggested strategies are more environmentally friendly than the reported one.

Head-To-Head Comparison Between Magnetic Resonance Imaging And Arthroscopy Findings For Ligamentous And Meniscal Knee Injuries: A Cross-Sectional Observational Study In Palestine, Zada Hamad, Ali Hewari, Aminah Birawi, Ahmed Awadghanem, Mazen Abdalla, Mohammad M. Jaber, Mosab Maree

Palestinian Medical and Pharmaceutical Journal

Background: Traumatic knee injuries are widespread, especially among young adults; when a clinical exam suspects the diagnosis, it is evaluated by magnetic resonance imaging (MRI) and confirmed by arthroscopy. MRI is non-invasive and saves patients from potential general anesthesia and surgical site infection complications. We aim to assess the precision of ligamentous and meniscal injuries by MRI compared to the gold standard knee arthroscopy. Methods: We performed a cross-sectional observational study at An-Najah University Hospital (NNUH). Patients who underwent knee arthroscopic surgery and had preoperative MRIs were included in this study. The magnetic resonance and intraoperative findings during …