Pharmacy and Pharmaceutical Sciences Commons^™

Sheehan Syndrome, Riya Jain, Shashidhara Kc, Savitha Savitha

Digital Journal of Clinical Medicine

No abstract provided.

Ectopia Lentis, Pratheek Prabhu

Digital Journal of Clinical Medicine

No abstract provided.

Cerebro-Vascular Accident, Mehak Gera, Rajendra Prasad, Suresh Babu, Manthappa M

Digital Journal of Clinical Medicine

No abstract provided.

Pulmonary Thromboembolism In A Case Of Alopecia Areata, Rakshith M

Digital Journal of Clinical Medicine

No abstract provided.

Predictors And Health Outcomes Of Treatment-Resistant Depression Among Adults With Chronic Non-Cancer Pain Conditions And Major Depressive Disorder, Drishti Shah

Graduate Theses, Dissertations, and Problem Reports (ETD)

Understanding major depressive disorder (MDD) as a comorbidity in patients with chronic non-cancer pain conditions (CNPC) is of importance because of the high prevalence and well documented bi-directional relationship between MDD and pain. Furthermore, presence of CNPC among adults with MDD often reduces benefits of antidepressant therapy, thereby increasing the possibility of treatment resistance. Treatment-resistant depression (TRD) commonly defined as insufficient response to multiple antidepressant trials, often worsens depression and pain symptoms and can amplify the clinical and economic burden among adults with CNPC and MDD. Additionally, long-term opioid therapy (LTOT) may be prescribed at a higher rate to adults …

Effects Of Naltrexone On Alcohol And Nicotine Use In Female P Rats, Usman Z. Hamid, Michael T. Bardo Ph.D.

Posters-at-the-Capitol

Title: Effects of Naltrexone on Alcohol and Nicotine Use in Female P Rats

Author: Usman Z. Hamid, Department of Psychology, University of Kentucky

Faculty Mentor: Michael T. Bardo, Ph.D., Department of Psychology, University of Kentucky

Alcohol is the most commonly abused substance worldwide. It is often co-abused with nicotine, which increases the difficulty of cessation of both alcohol and nicotine. Despite having similar mechanisms of action, there is no single medication to treat the co-abuse. The objective of the current study is to analyze the effects of the opiate antagonist naltrexone on alcohol consumption and the co-use of alcohol and …

Introduction To Pharmacy Law And Social Administrative Sciences I, Joanna Burkhardt

Library Impact Statements

No abstract provided.

Diffusion Through The Ex Vivo Vitreal Body – Bovine, Porcine, And Ovine Models Are Poor Surrogates For The Human Vitreous, Sara Shafaie, Victoria Hutter, Marc B. Brown, Michael T. Cook, David Y.S. Chau

Pharmacology and Animal Models in Research Collection

The human vitreous humour is a complex gel structure whose composition and physical properties can vary considerably from person to person and also change with age. To date, the viscoelastic properties of the human vitreous gel has not been thoroughly investigated and despite many years of intensive research, an ideal vitreous substitute remains a challenge. Understanding the physical structure and properties of the vitreous is of fundamental and therapeutic interest, providing a clear insight into diffusion and transport of administered ophthalmic drug molecules into the vitreous. A number of mammalian surrogates, mainly bovine, porcine and ovine vitreous humours have been …

Introduction To Safety To Quality In Healthcare Php 301g, Joanna Burkhardt

Library Impact Statements

No abstract provided.

Special Topics In Emerging Contaminants Php 579, Joanna Burkhardt

Library Impact Statements

No abstract provided.

#Drugfree: Using Social Media Advertisements To Spread Health On A College Campus, Amy M. Fanous, Benjamin D. Aronson, Jessica L. Hinson, Lindsey M. Peters, Breanna R. Meinzer, Zachary T. Woods, Michael J. Rush

Pharmacy Faculty Scholarship

No abstract provided.

Commencement Program 2018, Loma Linda University

Commencement Programs

CONTENTS

1 | Message from the President

3 | 2018 Events of Commencement

5 | The Academic Procession

7 | Significance of Academic Regalia

9 | The Good Samaritan

10 | University History Highlights

12 | Loma Linda University Song - "Healing Love"

13 | Criteria for Institutional Awards—Loma Linda University and Loma Linda University Health

15 | Loma Linda University Health and Loma Linda University Honorees

32 | The Programs, The School Honorees, and The Speakers

• School of Medicine, 33
• School of Pharmacy, 63
• School of Dentistry, 76
• School of Allied Health Professions - Allied Health Studies, Cardiopulmonary Sciences, …

Radical Social Ecology As Deep Pragmatism: A Call To The Abolition Of Systemic Dissonance And The Minimization Of Entropic Chaos, Arielle Brender

Student Theses 2015-Present

This paper aims to shed light on the dissonance caused by the superimposition of Dominant Human Systems on Natural Systems. I highlight the synthetic nature of Dominant Human Systems as egoic and linguistic phenomenon manufactured by a mere portion of the human population, which renders them inherently oppressive unto peoples and landscapes whose wisdom were barred from the design process. In pursuing a radical pragmatic approach to mending the simultaneous oppression and destruction of the human being and the earth, I highlight the necessity of minimizing entropic chaos caused by excess energy expenditure, an essential feature of systems that aim …

Swosu Research And Scholarly Activity Fair 2018, Lisa Appeddu, Cj Smith

SWOSU Research and Scholarly Activity Fair Programs

On behalf of the members of the Southwestern Oklahoma State University (SWOSU) University Research and Scholarly Activity Committee (USRAC) - Welcome to the Twenty-Fifth SWOSU Research and Scholarly Activity Fair! There are 130 poster presentations and 10 oral presentations involving 293 student researchers, writers, presenters, artists, collaborators, and faculty sponsors encompassing activities from the SWOSU College of Pharmacy; SWOSU School of Nursing & Allied Health Sciences; and SWOSU Departments of Art, Communication, & Theatre; Biological Sciences; Business & Computer Science; Chemistry and Physics; Education; Engineering Technology; Language & Literature; Music; Psychology; and Social Sciences. This also includes guest presenters from …

Analyzing The Differentiation Among State Medical Marijuana Policies By Examining State Policies & Trends, Richard Furlong

Political Science Theses and Capstones

Support for marijuana has been growing nationwide. This increased support has gained a lot of momentum since the late 1990s when California became the first state to legalize marijuana for medical use by enacting Proposition 215, or the Compassionate Use Act. Since the enactment of Proposition 215, 28 more states and the District of Columbia have legalized marijuana for medicinal use. I look into why states have begun to adopt these laws, and what makes these states differ throughout the country in the timeliness of their actions. I assembled data to examine a variety of state policies to attempt to …

We Are The Medicine, Madalynn Wendland, Toni Speed

Interprofessional Education

We are all healers— to ourselves, each other and the world around us. Whether you are on the path of becoming a health professional, or have been in practice for a long time, this half-day workshop will help you to view healing from a holistic perspective that draws from the ancient traditions while respecting contemporary science.

Public Health And Pharmacy Solutions For Opiod Use Disorder Php 336, Joanna Burkhardt

Library Impact Statements

No abstract provided.

Pharmaceutics Ii Bps 315, Joanna Burkhardt

Library Impact Statements

No abstract provided.

The Winding Road To Relapse: Forging A New Understanding Of Cue-Induced Reinstatement Models And Their Associated Neural Mechanisms, Mark D. Namba, Seven E. Tomek, M. Foster Olive, Joshua S. Beckmann, Cassandra D. Gipson

Psychology Faculty Publications

In drug addiction, cues previously associated with drug use can produce craving and frequently trigger the resumption of drug taking in individuals vulnerable to relapse. Environmental stimuli associated with drugs or natural reinforcers can become reliably conditioned to increase behavior that was previously reinforced. In preclinical models of addiction, these cues enhance both drug self-administration and reinstatement of drug seeking. In this review, we will dissociate the roles of conditioned stimuli as reinforcers from their modulatory or discriminative functions in producing drug-seeking behavior. As well, we will examine possible differences in neurobiological encoding underlying these functional differences. Specifically, we will …

The Challenged Brain Bps 205g, Joanna Burkhardt

Library Impact Statements

No abstract provided.

Prescription Drug Abuse, Jiaxi Tian

Global Issues in Public Health

Prescription drug abuse is an action that portrayed as misuse or overuse of prescription drugs. It is a prevalent problem all over the world. U.S is a particular country that has drug abuse as a serious problem has several different causes of the drug abuse. In the U.S., most prescription drugs are pain killers. The outcomes of drug abuse vary but may lead to death.

Macrophage Sensing Of Single- Walled Carbon Nanotubes Via Toll- Like Receptors, Sourav P. Mukherjee, Olesja Bondarenko, Pekka Kohonen, Fernando T. Andon, Tana Brzicova, Isabel Gessner, Sanjay Mathur, Massimo Bottini, Paolo Calligari, Lorenzo Stella, Elena Kisin, Anna Shvedova, Reija Autio, Heli Salminen-Mankonen, Ritta Lahesmaa, Bengt Fadeel

Faculty & Staff Scholarship

Carbon-based nanomaterials including carbon nanotubes (CNTs) have been shown to trigger

inflammation. However, how these materials are ‘sensed’ by immune cells is not known. Here we compared the effects of two carbon-based nanomaterials, single-walled CNTs (SWCNTs) and graphene oxide (GO), on primary human monocyte-derived macrophages. Genome-wide transcriptomics assessment was performed at sub-cytotoxic doses. Pathway analysis of the microarray data revealed pronounced effects on chemokine-encoding genes in macrophages exposed to SWCNTs, but not in response to GO, and these results were validated by multiplex array-based cytokine and chemokine profiling. Conditioned medium from SWCNT-exposed cells acted as a chemoattractant for dendritic cells. …

Statewide Cross-Sectional Survey Of Emergency Departments’ Adoption And Implementation Of The Ohio Opioid Prescribing Guidelines And Opioid Prescribing Practices, Jonathan Penm, Neil J. Mackinnon, Rebecca Mashni, Michael S. Lyons, Edmond A. Hooker, Erin L. Winstanley, Steve Carlton-Ford, Chloe Connelly, Erica Tolle, Jill Boone, Kathleen Koechlin, Jolene Defiore-Hyrmer

Faculty & Staff Scholarship

study objective: To evaluate the implementation of the Ohio Emergency and Acute Care Facility Opioids and Other Controlled Substances Prescribing Guidelines and their perceived impact on local policies and practice.

Methods: The study design was a cross-sectional survey of emergency department (ED) medical directors, or appropriate person identified by the hospital, perception of the impact of the Ohio ED Opioid Prescribing Guidelines on their departments practice. All hospitals with an ED in Ohio were contacted throughout October and November 2016. Distribution followed Dillman’s Tailored Design Method, augmented with telephone recruitment. Hospital chief executive officers were contacted when necessary to encourage …

Addressing Opioid Misuse And Abuse Through Interprofessional Engagement And Education, Marta J. Brooks, Suzanne E. Holm, Shelene Thomas, Amy J. Rich

Internet Journal of Allied Health Sciences and Practice

Purpose: The purpose of this initiative was to develop and implement an interprofessional panel aimed to expose a university audience to the magnitude of opioid misuse and abuse, as well as demonstrate each health professional’s role in curbing the epidemic. Further, this experience was to provide a platform for interprofessional discussion and to share with attendees tangible action items to begin combatting the opioid epidemic.

Methods: An interdisciplinary committee of healthcare professionals collaborated to initiate a dialogue around opioid misuse and abuse to highlight the power of interprofessional (IP) collaboration in addressing the opioid epidemic. Each panel member shared …

Implementing A Public Health Perspective In Fda Drug Regulation, Patricia J. Zettler, Margaret Foster Riley, Aaron S. Kesselheim

Faculty Publications By Year

There is, without question, a public health crisis in the United States arising from both illicit and prescription opioid misuse, addiction, and overdose. The Food and Drug Administration (FDA) is one regulator with an important role to play in minimizing the harms associated with prescription opioids, while also ensuring that prescription opioids are available for the evidence-based management of pain. One question, however, is to what extent the agency can consider in its decisions to approve opioids and keep existing ones on the market the provider and patient behaviors contributing to the epidemic. This is, in part, because FDA’s approval …

The Morality Of Compulsory Licensing As An Access To Medicines Tool, Margo A. Bagley

Faculty Articles

This Article contemplates the validity of theft rhetoric in relation to the right of countries to grant compulsory licenses from an unconventional perspective; that of biblical teachings on what it means to steal.

Part I describes the use of theft rhetoric in relation to IP infringement broadly and drug-patent compulsory licenses in particular.

Part II challenges the contention, suggested by theft rhetoric, that compulsory licenses are morally wrong as a form of stealing, by considering the meaning of theft in the context of its Judeo-Christian origins.

Part III considers the cogency of the accusation that the issuance of compulsory licenses …

The Prevention And Control Of Cancer By Metformin In Patients With Type 2 Diabetes: A Systematic Mapping Review Protocol, Michelle Price, Gabriela Cipriano, Albania Mitchell

Lavery Library Faculty/Staff Publications

No abstract provided.

Efforts To Reduce Concomitant Opioid And Benzodiazepine Prescribing At The Lexington Veterans Affairs Medical Center, Kaitlyn A. Staton

MPA/MPP/MPFM Capstone Projects

The United States is in the throes of an opioid epidemic. Any person who uses an opioid medication may experience an intentional or unintentional overdose. An overdose is more likely to occur when an individual ingests an opioid in combination with certain classes of medications, such as benzodiazepines or nonbenzodiazepines (Z-drugs). These medications are more likely to cause sedation and respiratory depression when taken together. Veterans, due to their unique mental and physical health challenges, are more likely to experience an overdose when they receive a combination of opioid therapy with benzodiazepine or Z-drug therapy as opposed to a single …

Discovery Of Natural Product Analogs Against Ethanol-Induced Cytotoxicity In Hippocampal Slice Cultures, Meredith A. Saunders-Mattingly

Theses and Dissertations--Psychology

An estimated 13.9% of Americans currently meet criteria for an alcohol (ethanol; EtOH) use disorder (AUD). While there are 4 medications approved by the Food and Drug Administration (FDA) to treat AUD, these treatments have demonstrated poor clinical efficacy. Our ongoing research program encompasses a multi-tiered screening of a natural product library and validation process to provide novel information about the mechanisms underlying EtOH-induced changes in neurobiology and to identify novel chemical scaffolds to be exploited in the development of pharmacological treatments for AUD in a rodent organotypic hippocampal slice culture model. Initial screens of several natural product compounds identified …

A 10-Year Bibliometric Study Of Pakistan Journal Of Pharmaceutical Sciences, Ishtiaq Ahmed, Midrar Ullah

Library Philosophy and Practice (e-journal)

Purpose

This study aims to carry out a bibliometric evaluation of articles published in Pakistan Journal of Pharmaceutical Sciences (PJPS) from 2006 to 2015. Bibliometric study determines publication pattern and identifies research trends in a field.

Design/Methodology/Approach

All articles published in PJPS during ten years were analysed using MS Excel.

Results

A total of 951 authors contributed 1172 articles to PJPS from 2006 to 2015. Eighty-six percent authors contributed only one article each. M. Saeed Arayne and Najma Sultana were the leading principal authors with 18 and 10 articles respectively. Ninety-seven percent articles were written by more than one author. …