Viruses Commons^™

Managing Aphids And Viruses In Lupins, Department Of Primary Industries And Regional Development, Western Australia

Grains and other field crops factsheets

Aphids reduce yields by direct feeding damage, which causes flower and pod abortion and occasionally plant death in lupins. The extent of damage varies between seasons, but losses can be severe in years that favour aphid population development.

Lupins are most vulnerable to aphids during budding and flowering, as severe feeding damage on growing tips can cause buds to drop, flowers to abort, and reduced pod set. Some lupin varieties are more susceptible to aphids than others.

Aphids transmit serious virus diseases, which reduce yields and contaminate seed stocks. Some species of aphids are more difficult to control than others.

Hide & Cru-Seq: Investigating Potential Crucivirus Hosts With Fluorescently Labeled Protein, Marcell Devaune Richard, Nacho De La Higuera, Jono Abshier, Ken Stedman

Student Research Symposium

Cruciviruses are DNA viruses that contain a capsid protein that shares striking similarities to capsid proteins from RNA viruses. Formerly known as “RNA-DNA hybrid viruses”, this novel type of viruses suggest gene exchange between unrelated RNA and DNA viruses. However, the hosts of cruciviruses remain unknown. To investigate this groundbreaking virus genome further, utilization of the predicted viral host recognition domain (P-domain) fused to a thermal green protein and a histidine tag, allows investigation of crucivirus hosts in environments where these viruses have been discovered. Using cruciviruses that have been found in soil samples on the PSU campus, along with …

Exploration Of Potential Broad-Spectrum Antiviral Targets In The Enterovirus Replication Element: Identification Of Six Distinct 5' Cloverleaves, Morgan G. Daniels, Meagan E. Werner, Rockwell T. Li, Steven M. Pascal

Chemistry & Biochemistry Faculty Publications

Enterovirus genomic replication initiates at a predicted RNA cloverleaf (5′CL) at the 5′ end of the RNA genome. The 5′CL contains one stem (SA) and three stem-loops (SLB, SLC, SLD). Here, we present an analysis of 5′CL conservation and divergence for 209 human health-related serotypes from the enterovirus genus, including enterovirus and rhinovirus species. Phylogenetic analysis indicates six distinct 5′CL serotypes that only partially correlate with the species definition. Additional findings include that 5′CL sequence conservation is higher between the EV species than between the RV species, the 5′CL of EVA and EVB are nearly identical, and RVC has the …

Editorial: Pathogens, Pathobionts, And Autoimmunity, Linda A. Spatz, Gregg J. Silverman, Judith A. James

Publications and Research

No abstract provided.

Structural Biology Of The Enterovirus Replication-Linked 5'-Cloverleaf Rna And Associated Virus Proteins, Steven M. Pascal, Ravindranath Garimella, Meghan S. Warden, Komala Ponniah

Chemistry & Biochemistry Faculty Publications

Although enteroviruses are associated with a wide variety of diseases and conditions, their mode of replication is well conserved. Their genome is carried as a single, positive-sense RNA strand. At the 5′ end of the strand is an approximately 90-nucleotide self-complementary region called the 5′ cloverleaf, or the oriL. This noncoding region serves as a platform upon which host and virus proteins, including the 3B, 3C, and 3D virus proteins, assemble in order to initiate replication of a negative-sense RNA strand. The negative strand in turn serves as a template for synthesis of multiple positive-sense RNA strands. Building on structural …

Direct Cell-To-Cell Transmission Of Respiratory Viruses: The Fast Lanes, Nicolás P. Cifuentes-Muñoz, Rebecca Ellis Dutch, Roberto Cattaneo

Molecular and Cellular Biochemistry Faculty Publications

Virus particles protect genomes from hostile environments within and outside the host, eventually delivering these genomes to target tissues to initiate infection. Complex processes requiring significant energy and time are necessary to assemble these virus particles, but only a small portion of released virus will successfully infect new target cells (Fig 1A). While the science of virology has developed based on the isolation and purification of viral particles, it is becoming increasingly clear that direct cell-to-cell transmission of viruses and/or viral components is also highly relevant [1,2].

Direct cell-to-cell spread of infections has several advantages. The first is efficiency: genomic …

Bacteriophages: The Answer To Antibiotic Resistance?, Allie Casto, Adam Hurwitz, Kunny Kou, Gregory Mansour, Allison Mayzel, Rachel Policke, Alexander Schmidt, Rowan Shartel, Olivia Smith, Augustus Snyder, Allison Woolf

James Madison Undergraduate Research Journal (JMURJ)

Bacteriophages, viruses that infect bacteria, have numerous applications in the medical, agricultural, and research fields, especially as an alternative to antibiotics in the age of antibiotic resistance. Phages are able to lyse, or break apart, bacterial cells with fewer side effects, more specificity, and less likelihood of resistance than antibiotics. The acceptance of phages in medicine and agriculture around the world today is not universal, and the United States Food and Drug Administration (FDA) has been slow to recognize phage therapy as a legitimate treatment. However, the successful use of phages in the past, as well as promising trial results …

Isolation And Enumeration Of Enteric Viruses From Primary Wastewater Sludge, Michael Wayne Nath

Biological Sciences Theses & Dissertations

The presence of large numbers of enteric viruses in wastewaters has resulted in concern regarding their significance and consequences for humans. Assessments of relative significance or consequences may most accurately be made following precise measurements of the range of virus types and amounts in wastewaters and sludges and after epidemiological considerations. In this study, results are presented pertaining to enteric virus isolation, concentration, and enumeration from primary wastewater sludges.

As an integral part of a comparison of isolation procedures, several anionic surfactants were examined for extraction of enteric viruses from primary wastewater sludges. Plaquing efficiencies for poliovirus type 2 and …

Comparison Of Interferon Produced In Vitro By Monkey Kidney Cells Demonstrating Interference Against Polio Ii, Coxsackie A-9, Influenza A2/Hong Kong/68, And Echo-9 Viruses, Archer Duncan Farmer Jr.

Biological Sciences Theses & Dissertations

Abstract unavailable