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Full-Text Articles in Animals

The Pam-1 Aminopeptidase Protects Against Neurodegeneration In Caenorhabditis Elegans, Caleb Coil May 2024

The Pam-1 Aminopeptidase Protects Against Neurodegeneration In Caenorhabditis Elegans, Caleb Coil

Honors College Theses

The deteriorating effects of neurodegenerative conditions seem inescapable for many as they age. The experimental exploration of the molecular and cellular mechanisms responsible for neurodegeneration is aided using animal models. For instance, genetic screens have identified the puromycin-sensitive aminopeptidase (PSA) as a novel effector of neurodegeneration, as mutations in PSA in fruit flies result in perturbations of neuron anatomy and an accelerated onset of neuron death. We have tested the hypothesis that PAM-1, the Caenorhabditis elegans ortholog of PSA, plays a similar role in governing neurodegeneration in nematodes. Genetic strains were created that express the green fluorescent protein (GFP) in …


Breed Quality Scores For Post-Cervical Artificial Insemination And The Effects On Farrowing Rate And Total Born At A Commercial Swine Facility In The Southern United States, Kathryn R. Prus Jan 2017

Breed Quality Scores For Post-Cervical Artificial Insemination And The Effects On Farrowing Rate And Total Born At A Commercial Swine Facility In The Southern United States, Kathryn R. Prus

Murray State Theses and Dissertations

The objective of this experiment was to determine the possible relationship between a sow’s ease of breeding on the first service and the farrowing rate and total born. This study was conducted in a commercial farrowing unit in the Southern United States utilizing pen gestation with stock of 6,000 head. Five hundred ninety-seven sows were bred between the months of April and May 2017 were selected for this study. All animals were inseminated using a post-cervical artificial insemination catheter unless insertion of the inner catheter was impossible. The semen dose fell within the following parameters: concentration of 1.5 x 10 …