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Characterization Of Transmembrane Protein 35 Expression: Considerations Of Sex And Ovarian Hormones, Amanda M. Vanderplow
Characterization Of Transmembrane Protein 35 Expression: Considerations Of Sex And Ovarian Hormones, Amanda M. Vanderplow
All NMU Master's Theses
The recently discovered novel neuropeptide transmembrane protein 35 (TMEM35), is believed to modulate chemical signaling within the nervous system. Notably, the TMEM35 protein is detectable in humans, non-human primates and rodents, suggesting a conserved and critical function. Despite this, the functions of TMEM35 are ill-defined in the nervous system and insufficiently studied (currently only three publications). Previous work has identified high expression of TMEM35 in both the ventromedial hypothalamus (VMH) and the limbic circuit of the mouse brain. Due to the known functions of these two regions, this pattern of expression indicates possible roles of this neuropeptide in social behavior …