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Articles 1 - 4 of 4
Full-Text Articles in Organisms
Homeotic Gene Teashirt (Tsh) Has A Neuroprotective Function In Amyloid-Beta 42 Mediated Neurodegeneration., Michael M. Moran, Madhuri Kango-Singh, Amit Singh
Homeotic Gene Teashirt (Tsh) Has A Neuroprotective Function In Amyloid-Beta 42 Mediated Neurodegeneration., Michael M. Moran, Madhuri Kango-Singh, Amit Singh
Amit Singh
Background: Alzheimer's disease (AD) is a debilitating age related progressive neurodegenerative disorder characterized by the loss of cognition, and eventual death of the affected individual. One of the major causes of AD is the accumulation of Amyloid-beta 42 (Aβ42) polypeptides formed by the improper cleavage of amyloid precursor protein (APP) in the brain. These plaques disrupt normal cellular processes through oxidative stress and aberrant signaling resulting in the loss of synaptic activity and death of the neurons. However, the detailed genetic mechanism(s) responsible for this neurodegeneration still remain elusive. Methodology/ Principle Findings: We have generated a transgenic Drosophila eye model …
Welcome To The Journal Of Evolution And Health, Aaron Blaisdell, Paul Jaminet, David C. Pendergrass
Welcome To The Journal Of Evolution And Health, Aaron Blaisdell, Paul Jaminet, David C. Pendergrass
Aaron P Blaisdell
Welcome to the first issue of the Journal of Evolution and Health! The Journal of Evolution and Health is the peer-reviewed, open-access journal of the Ancestral Health Society, a community of scientists, healthcare professionals, and laypersons who collaborate to understand health challenges from an evolutionary perspective.
Phytochemistry And Pharmacology Of Plants From The Ginger Family, Zingiberaceae, Hans Wohlmuth
Phytochemistry And Pharmacology Of Plants From The Ginger Family, Zingiberaceae, Hans Wohlmuth
Dr Hans Wohlmuth
This thesis reports on a series of investigations into the phytochemistry and pharmacology of plants belonging to the ginger family, Zingiberaceae (incl. Costaceae). The work falls into two main parts. The first part examines the pungent compounds and essential oil in 17 clones of ginger (Zingiber officinale) with a view to identify one or more with unique chemistry and consequent particular therapeutic (or flavouring) prospects. The second part comprises the screening of 41 taxa for inhibition of PGE2 and other biological activities, with the primary aim of identifying species with potential anti-inflammatory activity. This part tested the hypothesis that the …
High-Throughput Genome Sequencing Of Lichenizing Fungi To Assess Gene Loss In The Ammonium Transporter/Ammonia Permease Gene Family, Tami R. Mcdonald, Olaf Mueller, Fred S. Dietrich, François Lutzoni
High-Throughput Genome Sequencing Of Lichenizing Fungi To Assess Gene Loss In The Ammonium Transporter/Ammonia Permease Gene Family, Tami R. Mcdonald, Olaf Mueller, Fred S. Dietrich, François Lutzoni
Tami McDonald
No abstract provided.