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Articles 1 - 11 of 11
Full-Text Articles in Optometry
Visionary 2008, College Of Optometry
Diagnostic Sensitivity/Specificity Of Preattentive Vision Tests In Glaucoma, James Loughman, Peter Davison, Daniel Ian Flitcroft
Diagnostic Sensitivity/Specificity Of Preattentive Vision Tests In Glaucoma, James Loughman, Peter Davison, Daniel Ian Flitcroft
Articles
Purpose. Damage to the nerve fiber layer or visual pathway might be expected to reduce the efficiency with which the visual system performs analysis of the ever-changing field of vision. The purpose of this article is to provide a further analysis of previously reported data (Loughman J, Davison P, Flitcroft I, Br J Ophthalmol 2007;91:1493-98.) to: (i) determine the sensitivity and specificity of a test of preattentive vision for glaucoma detection and (ii) provide a cutoff performance level that would serve to distinguish glaucoma in early cases. Methods. Three groups of observers (glaucoma, suspects, and normals) were examined, using computer-generated …
Diagnostic Sensitivity/Specificity Of Preattentive Vision Tests In Glaucoma, James Loughman, Peter Davison, Daniel Ian Flitcroft
Diagnostic Sensitivity/Specificity Of Preattentive Vision Tests In Glaucoma, James Loughman, Peter Davison, Daniel Ian Flitcroft
Articles
Purpose. Damage to the nerve fiber layer or visual pathway might be expected to reduce the efficiency with which the visual system performs analysis of the ever-changing field of vision. The purpose of this article is to provide a further analysis of previously reported data (Loughman J, Davison P, Flitcroft I, Br J Ophthalmol 2007;91:1493–98.) to: (i) determine the sensitivity and specificity of a test of preattentive vision for glaucoma detection and (ii) provide a cutoff performance level that would serve to distinguish glaucoma in early cases. Methods. Three groups of observers (glaucoma, suspects, and normals) were examined, using computer-generated …
Ocular Aberrations Wavefront Sensor In Clinical Application, Matthew Sheehan
Ocular Aberrations Wavefront Sensor In Clinical Application, Matthew Sheehan
Masters
A versatile Hartmann-Shack (HS) wavefront sensor (WFS) was designed and constructed. Its advantages include simultaneous pupil centre determination, off-axis capability, realtime data displays, and efficient lenslet sampling orientation. The instrument is compact and transportable, making it convenient for use in a clinical setting. Subject alignment is achieved by the use of a parallel channel that is recombined with the sensing channel to simultaneously image the external eye and the HS spots onto a single charge coupled device (CCD). The pupil centre is determined using this image of the eye, rather than the HS spots. Off-axis measurements are possible throughout an …
Health Professions Division Catalog 2008-2009, Nova Southeastern University
Health Professions Division Catalog 2008-2009, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
College Of Optometry Program Overview, Nova Southeastern University
College Of Optometry Program Overview, Nova Southeastern University
Health Professions Divisions Course Catalogs and Course Descriptions
No abstract provided.
Structural And Functional Properties Of Human Αa-Crystallin, Jose Mauro Chaves
Structural And Functional Properties Of Human Αa-Crystallin, Jose Mauro Chaves
All ETDs from UAB
The three specific aims of the project were: (1) compare effects of deamidation alone (i.e., αA-N101D, αA-N123D, αA-N101/123D), truncation alone (αA-NT mutant [deletion of residue no. 1-63], or αA-CT mutant [deletion of residue no. 140-173]), or both truncation plus deamidation on structural and functional properties of human lens αA-crystallin; (2) identify components of complexes in the water soluble-high molecular weight (WS-HMW) proteins of normal aging and cataractous human lenses; and (3) determine interactions among WT-αA, αA-NT and αA-CT crystallin species with filensin and phakinin (beaded filament proteins) in vitro. The comparative structural and functional differences between αA-deamidated and/or truncated mutants …
Punctal Occlusion Impact On Tear Film Immuno-Regulatory Proteins Measured By Cytometric Bead-Based Assay, Martin W. Lafrance
Punctal Occlusion Impact On Tear Film Immuno-Regulatory Proteins Measured By Cytometric Bead-Based Assay, Martin W. Lafrance
All ETDs from UAB
PURPOSE: This study compares vendor reagents used for cytometric bead-based assay (CBA) of cytokines in human tears and validates a protocol for use in evaluating punctal occlusion, a treatment for keratoconjunctivitis sicca. It has been proposed that punctal occlusion may alter tear cytokine concentrations based on the facts that: (1) tear clearance, a measure of the balance between tear production and elimination, declines following occlusion and (2) reduced tear clearance and increased levels of pro-inflammatory tear cytokines are correlated in dry eye patients. This study compares tear clearance values and the level of 24 tear cytokines measured by CBA following …
The Role Of Melanopsin Containing Retinal Ganglion Cells In The Pupillary Responses Of Human And Non-Human Primates, David H. Mcdougal
The Role Of Melanopsin Containing Retinal Ganglion Cells In The Pupillary Responses Of Human And Non-Human Primates, David H. Mcdougal
All ETDs from UAB
Historically, the characteristics of the light-evoked neural signals driving the human pupillary light reflex (PLR) have been poorly understood. It was assumed that these light signals originated exclusively from rod and cone photoreceptors, although the measured spectral sensitivity and response dynamics of the PLR were difficult to reconcile with the known properties of rods and cones. Recently, a novel photoreceptive cell class has been discovered in the mammalian retina. These unique retinal ganglion cells not only receive rod and cone inputs, but also express the photopigment melanopsin, and exhibit intrinsic photoresponses independent of rod and cone inputs. These intrinsically photosensitive …
The Role Of Strychnine-Sensitive Nachrs In Rabbit Retinal Off Ganglion Cells, Jordan Michael Renna
The Role Of Strychnine-Sensitive Nachrs In Rabbit Retinal Off Ganglion Cells, Jordan Michael Renna
All ETDs from UAB
that when heteroskedasticity is present, but ignored, there is significant evidence to suggest
Expression And Function Of Nicotinic Acetylcholine Receptors In Human Vascular Endothelial Cells, Ryan C. Splittgerber
Expression And Function Of Nicotinic Acetylcholine Receptors In Human Vascular Endothelial Cells, Ryan C. Splittgerber
All ETDs from UAB
Neuronal nicotinic acetylcholine receptors (nAChRs) are widely expressed in neural and non-neural tissues and have been reported to play a role in neovascularization and vascular diseases of the eye, specifically age-related macular degeneration (ARMD). However, the subunit composition of functional nAChRs, their mechanisms of action, and the downstream signaling pathways in non-neuronal tissues are not well understood. Since some nAChR subtypes have high Ca2+ permeability, we investigated the possible role of Ca2+ in activating signaling cascades that underlie the affects of nAChR activation in Human Dermal Microvascular Endothelial Cells (HDMECs). RT-PCR experiments revealed message for nearly all of the known …