Mental and Social Health Commons^™

The Sun Shines Beyond The Mountains: The Creation Of A Suicidality Needs Assessment For Lesotho, Layhla Currier

Theses/Capstones/Creative Projects

The country of Lesotho has the highest suicide mortality rate in the world. Although this is true, there has seldom been research into the cause of this astronomical rate, and even less evaluating how to address the issue. This study focused on the analysis of available data to better understand the possible causes of the high suicide rate in Lesotho. Additionally, a suicidality needs assessment was created to collect data regarding mental health, social support, risk factors, and previous suicidality from Basotho (moniker for residents of Lesotho) in a non-stigmatizing way. Two varying suicidality assessments were used to create this …

Comparing Online And In-Person Social Support And Its Effects On Suicidal Ideation, Alexander J. Potter

Honors Theses

According to the interpersonal theory of suicide, thwarted belonging and perceived burdensomeness are proximal causes of suicidal ideation (Van Orden et al., 2010). Studies show that a lack of social support can lead to higher levels of thwarted belonging and perceived burdensomeness (Sparks et al., 2023). This relationship between social support and suicidal ideation has been studied in the literature, but the relationship between online and in-person social support with suicidal ideation has not. The purpose of the current study is to examine the effects of in-person and online social support on different factors of the interpersonal theory of suicide. …

To Heal A Mind: A Comparison Of Functional And Conventional Treatments In Major Depressive Disorder, Gillian Chambers

Senior Honors Theses

Incidence of major depressive disorder is increasing year over year, with little able to be done to halt the spread of the condition. However, there are many treatment possibilities considered unconventional by the healthcare system. This thesis examines the respective benefits and risks, in comparison to one another, between conventional pharmacological treatment and functional, holistic treatment of depression. This was done via integrative review of available clinical literature, synthesizing evidence on both conventional and functional treatments for depression, as dictated by Whittemore and Knafl (2005). Exploratory search methods revealed 758 records fulfilling inclusion criteria, which were screened and narrowed down …

Bibliography For "Mindfulness Reference Display", Isabella Piechota, Arianna Tillman, Annikah Carpio

Library Displays and Bibliographies

A bibliography created to support a display about mindfulness in May 2025 at the Leatherby Libraries at Chapman University.

Kansas City, Kansas, Vida Davidović

Department of English: Dissertations, Theses, and Student Research

KANSAS CITY, KANSAS is a thesis that operates in the tradition of expressionist dramaturgy and playwriting, taking up themes of abuse, imperialism, war, trauma, womanhood, Balkan identities, history of the Balkans, as well as the discourses of psychoanalysis and postcolonial theory. The use of different theoretical frameworks related to both international and personal politics, which are shown to be intertwined, suggests a strong relationship between political processes in the Second World Countries that had experienced many occupations throughout their history and the way women in those countries relate to the questions of body, authority, feminity, and interpersonal relationships. The play …

Dr. Doctor: A Look At Life In Medicine, Alexandra Hausmann

Honors Program: Senior Projects (Public)

The life of a medical professional is not easy. The road to get there and the lifestyle when practicing is mentally draining and results in many physicians experiencing burnout. This project and paper explore the stigma surrounding mental health in medicine, examining how fear of professional repercussions prevents many physicians from getting help. Through research and interviews with medical professionals of various specialties, this project looks at the different mental health struggles that each specialty faces. Additionally due to increased social media, medicine continues to evolve at a fast rate. Looking forward, medical professionals will have to deal with increased …

“Re-Storying” Anne Shirley And The Adhd Child: A Crip Genealogy Of Anne Of Green Gables, Darian Aleyna Wilson

Department of English: Dissertations, Theses, and Student Research

This thesis explores the contested nature of Attention Deficit Hyperactivity Disorder (ADHD), focusing on its cultural and historical constructions. While ADHD has been included in the Diagnostic and Statistical Manual of Mental Disorders since 1980, its legitimacy remains a subject of debate across medical, disability studies, and historical scholarship. Using Eli Clare’s critique of diagnosis as a tool rather than a fact, this project examines how ADHD is both pathologized and re-storied within societal and medical discourses. It highlights the tension between medical classifications and lived experiences of those diagnosed with ADHD, particularly in the context of girlhood.

The central …

Exploring The Nexus Of Adverse Childhood Experiences And Illicit Substance Misuse Among Midwestern Adults, Anika R. Eisenbraun

Department of Sociology: Dissertations, Theses, and Student Research

The positive association between illicit substance misuse and adverse childhood experiences (ACEs) has been widely examined in prior literature. Yet, there is limited understanding of the varying factors, such as social support, depressive symptoms, or sexual victimization, that may impact the relationship between substance misuse and ACEs. As such, the purpose of the current study is to examine the relationship between ACEs (i.e., physical and emotional abuse, sexual abuse, neglect) with illicit substance misuse and to investigate indirect pathways of social support, depressive symptoms, and sexual victimization. Private, secondary data from the second cohort of a larger, longitudinal rural health …

The Relationships Between Behavioral And Sociocultural Constructs And Electronic Nicotine Delivery Systems (Ends) And Cannabis Patterns In Hispanic Young Adult University Students, Kevin Sandoval Medina

Open Access Theses & Dissertations

The proliferation of both electronic nicotine delivery systems (ENDS) and cannabis has contributed to a concerning trend of dual usage, posing a greater public health risk, particularly pronounced among at-risk populations of increased substance use, such as Hispanic young adult college students. This study utilized the socioecological framework and social cognitive theory to observe behavioral and sociocultural constructs associated with dual use and identify potential risk and protective factors. Four hundred and twenty-one Hispanic young adult university students completed a cross-sectional survey assessing sociodemographics, depression, anxiety, stress, familism, acculturation, self-efficacy, and past month dual use and dual use recency of …

"Alone I Can't, But Together We Can": A Photovoice Study To Explore Insights Of Assisted Outpatient Treatment (Aot) From Providers Working With Individuals With Serious Mental Illness (Smi)., Monica G. Urquieta

Open Access Theses & Dissertations

Assisted Outpatient Treatment (AOT) is a court-ordered mental health treatment program for individuals with SMI (bipolar disorder, major depressive disorder and schizophrenia) who have a history of noncompliance with treatment and are at risk of deteriorating or causing harm to themselves or others. This dissertation examined the perceptions and experiences of thirteen providers (lawyers, judges, case managers, psychiatrists, housing navigators, treatment guardians, nurse practitioners, therapists and peer support specialists with lived experience) on the AOT program for clients with SMI; and the environments that shape these perceptions, taking into account a system and community-based approach focusing on how the unique …

The Impact Of Cocaine On Inflammatory Markers In Sim-A9 Microglial Cells, Tyler Vaglivelo

Honors Scholar Theses

Substance use disorders are conditions in which an individual continues to use a drug or other substance despite adverse consequences to their health and well-being. It has been hypothesized that inflammation within the central nervous system plays a critical role in the development of substance use disorders. The resident macrophages in the brain, also known as microglia, release markers of inflammation in response to injury or infection. A better understanding of the inflammatory response mediated by microglia in response to drugs of misuse can validate this hypothesis and help guide drug development. In the current studies, the microglia cell line …

Exercise As An Intervention For Postpartum Depression (Ppd), Kylie P. Mistretta

Honors Scholar Theses

Objective: To illustrate the applications of exercise for preventing the development of postpartum depression (PPD) and addressing associated risk factors identified in the literature. Data Sources: PubMed and EBSCO: Academic Search Premier were accessed using the search terms exercise OR physical activity OR yoga AND postpartum depression OR postnatal depression. A secondary search of PubMed was conducted using the search terms exercise AND pregnancy AND depression OR gestational diabetes OR weight gain OR sleep quality.

Study Selection: Studies selected for inclusion were peer-reviewed, published after January 2012, written in English, and relevant to the PPD risk factors examined. Only clinical …

Neuroimaging-Based Variability In Subtyping Biomarkers For Psychiatric Heterogeneity, Zhenfu Wen, Mira Z Hammoud, Carole E Siegel, Eugene M Laska, Duna Abu-Amara, Amit Etkin, Mohammed R Milad, Charles R Marmar

Faculty, Staff and Student Publications

Neuroimaging-based subtyping is increasingly used to explain heterogeneity in psychiatric disorders. However, the clinical utility of these subtyping efforts remains unclear, and replication has been challenging. Here we examined how the choice of neuroimaging measures influences the derivation of neuro-subtypes and the consequences for clinical delineation. On a clinically heterogeneous dataset (total n = 566) that included controls (n = 268) and cases (n = 298) of psychiatric conditions, including individuals diagnosed with post-traumatic stress disorder (PTSD), traumatic brain injury (TBI), and comorbidity of both (PTSD&TBI), we identified neuro-subtypes among the cases using either structural, resting-state, or task-based measures. The …

Perception Of Mental Health Among Students In Higher Education, Kasibah Baig, Leia Aguilar

Electronic Theses, Projects, and Dissertations

Mental health in higher education environments is a topic that has the need for exploration and discussion. Students with poor mental health face additional stressors and challenges in their academic and personal areas of life. It is critical for colleges and universities to address the topic of mental health and understand how it can affect students, as well as to be able to provide the proper support and services. By having more conversations about mental health on campus and providing easily accessible and inclusive resources for students, it can create a comfortable environment on campus for students to be able …

The Impact Of Attachment Education On Families With Children Diagnosed With Autism Spectrum Disorder: A Proposed Workshop, Sabrina S. Stone-Smith

Electronic Theses, Projects, and Dissertations

For young children with autism spectrum disorder, one important determinant of later social and emotional functioning is the development of a secure attachment. While there is extensive literature outlining the benefits of attachment security, there is a limited number of studies specifically examining programs intended to increase attachment security in this population. This project aims to create a four-session workshop designed to provide caregivers of children in this population with information about attachment theory and parental sensitivity in order to increase the amount of positive and emotionally validating experiences in child-caregiver interactions while reducing parental stress. Future research is necessary …

#Toomuchcontent: A Quantitative Analysis On Social Media Time Usage And Its Impact On Young Adult Anxiety And/Or Depression In The United States, Sarah Juarez

Electronic Theses, Projects, and Dissertations

As technology continues to advance and grow, society has seen a surge in popularity of various social media sites. Social media has become increasingly popular among young adults, with some spending over 10 hours each day on social media. Social media can be utilized for community building, fostering relationships, providing safe spaces, inspiration, creative expression, and may even provide users with acceptance, validation, and a sense of belonging. Considering these factors, social media may also affect individuals negatively— specifically mental health-wise, in terms of anxiety and depression. This study aimed to identify whether a correlation exists between time spent on …

The Role Of Self Esteem Upon The Recovery Of Eating Disordered Patients, Samanta Flores Velazquez

Undergraduate Honors Theses

Eating disorders such as anorexia-nervosa, bulimia-nervosa, and binge-eating disorders are detrimental to overall health and well-being. The demands of beauty ideals and attitudes impact young adults negatively as they attempt to meet societal beauty standards. The need for approval, fitting in with the community, and confidence drive the behaviors of people in negative ways. In recent years, the modernization of social media has contributed to dieting cultures, the thin ideal, harmful weight-loss practices, and the cycle to use the body as a means to control or repent. External factors affect the risk of eating disorders which contribute to the challenge …

Misconceptions Among Mental Health Treatment Providers About Ocd And Ptsd, Caitlin M Pinciotti, Gabriella T Ponzini, Gianna M Colombo, Carmen P Mclean, Terri L Fletcher, Natalie E Hundt, Lauren P Wadsworth, Nathaniel Van Kirk, Stephanie Y Wells, Jonathan S Abramowitz, Wayne K Goodman, Eric A Storch

Faculty, Staff and Students Publications

Obsessive-compulsive disorder (OCD) and posttraumatic stress disorder (PTSD) share overlapping features for which similar cognitive behavioral treatment (CBT) strategies can be employed. However, the comorbid presence of these conditions poses unique clinical considerations, and a nuanced approach to assessment, conceptualization, and treatment is needed when working with individuals with co-occurring OCD and PTSD. Treatment providers may not be aware of these nuances and may hold misconceptions about co-occurring OCD and PTSD, impacting their approach to assessment, conceptualization, and treatment. The current study sought to examine possible misconceptions among mental health treatment providers of differing specializations. Among 146 primarily CBT-oriented treatment …

Circulating Epstein-Barr Virus Antibody Levels As A Biomarker Of Socioecological Adversity In Amazonian Ecuador, Tyler M Barrett, Melissa A Liebert, Geeta N Eick, Julia G Ridgeway-Diaz, Felicia C Madimenos, Aaron D Blackwell, Tara J Cepon-Robins, Samuel S Urlacher, Lawrence S Sugiyama, J Josh Snodgrass

Faculty, Staff and Students Publications

Objectives: Circulating Epstein-Barr virus antibodies (EBV-Ab) are used as a biomarker of chronic stress in high-income settings, but their relevance in environments with a high burden of infectious disease, nutritional constraints, and limited resources is less clear. We investigated EBV-Ab as a biomarker of adversity in a setting where local ecology and economy may affect immune development differently than in wealthy countries.

Methods: We measured EBV-Ab in finger-prick dried blood spots collected from Indigenous Shuar (n = 433) and non-Indigenous Colonos (n = 84) ranging from < 1 to 87 years old in Amazonian Ecuador. For a subset of adults (≥ 15 years, n = 210), we collected socioeconomic information (income, education, and occupation) and assessed household-level market integration. We determined the most important predictors of EBV-Ab for adults and children using multi-model averaging of linear regression models.

Results: Male children (< 15 years) had lower EBV-Ab than female children (model averaged β [SE]: -0.238 [0.066]). For adults, Shuar had higher EBV-Ab than Colonos (model averaged β [SE]: 0.235 [0.113]), and high systolic blood pressure was an important predictor of elevated EBV-Ab (model averaged β [SE]: 0.088 [0.047]). Individuals who reported unpaid domestic work as their primary occupation had higher EBV-Ab than agricultural workers (model averaged β [SE]: 0.302 [0.113]). Individuals living in houses with more market-sourced infrastructure had lower EBV-Ab (model averaged β [SE]: -0.088 [0.068]).

Conclusions: Circulating EBV-Ab may capture context-specific aspects of socioecological adversity …

Azetukalner, A Novel Kv7 Potassium Channel Opener, In Adults With Major Depressive Disorder: A Randomized Clinical Trial, Noam N Butterfield, Constanza Luzon Rosenblut, Maurizio Fava, Christoph U Correll, Anthony J Rothschild, James W Murrough, Sanjay J Mathew, Gregory N Beatch, Celene Grayson, Cynthia Harden, Jenny Qian, Joe Mcintosh, Rostam Namdari, Christopher Kenney

Staff and Researcher Publications

Importance: Available antidepressants provide inadequate therapeutic responses in many patients with major depressive disorder (MDD), highlighting a substantial unmet need.

Objective: To evaluate the efficacy and safety of azetukalner, a novel, potent KV7 potassium channel opener, in participants with MDD.

Design, setting, and participants: X-NOVA was a multicenter, proof-of-concept, phase 2, randomized, double-blind, parallel-group, placebo-controlled clinical trial that evaluated azetukalner in participants (adults aged ≥18 to ≤65 years) with moderate to severe MDD in a current depressive episode. Participants were enrolled between April 2022 and October 2023, and data analysis occurred from January 2023 to January 2024.

Intervention: Participants were …

Navacaprant, A Novel And Highly Selective Kappa Opioid Receptor Antagonist, In Adults With Major Depressive Disorder: A Randomized, Double-Blind Phase 2 Clinical Trial, Sanjay J Mathew, Andrew J Cutler, Nicole C Visitacion, Michael Gold, Jason Yuan, Bill Aurora

Staff and Researcher Publications

PURPOSE/BACKGROUND: This phase 2a randomized, double-blind, placebo-controlled, 8-week trial assessed the efficacy and safety of navacaprant, a highly selective kappa opioid receptor antagonist, in adults with major depressive disorder (MDD).

METHODS/PROCEDURES: Participants with 17-Item Hamilton Depression Rating Scale (HAMD-17) scores of 14 to 30 were randomized 1:1 to once-daily navacaprant 80 mg or placebo (n = 102 each). The primary endpoint was HAMD-17 change from baseline (CFB) to week 8. Secondary endpoints included CFB in Snaith-Hamilton Pleasure Scale (SHAPS). No adjustment for multiple comparisons was made.

FINDINGS/RESULTS: At week 8, HAMD-17 CFB was not statistically significantly improved with navacaprant vs …

Produce Prescription Policy Project For The Securement Of A Grant To Address Food Insecurity For Low-Income Type Ii Diabetic Patients, Isabel D. Garcia-Gallegos

Doctor of Nursing Practice Final Project Abstract

PURPOSE

This policy-focused Doctor of Nursing Practice (DNP) quality improvement (QI) project aims to secure grant funding through the Gus Schumacher Nutrition Incentive Program (GusNIP) to implement a produce prescription program at a community clinic in Texas. The program targets low-income adults (18-65 years) with type II diabetes who experience food insecurity and are affected by Medicaid non-expansion.

BACKGROUND

Texas’ decision not to expand Medicaid has exacerbated food insecurity among low-income residents, particularly those managing type II diabetes. This decision creates a healthcare policy gap that this project aims to address with a food-as-medicine program.

METHODOLOGY

Using the Plan-Do-Study-Act (PDSA) …

Investigating Mental Health Outcomes Of National Collegiate Athletic Association (Ncaa) Division I Student-Athletes At The University Of Louisville, 2019-2023., Paul Harvey

Electronic Theses and Dissertations

Mental health outcomes among collegiate student-athletes, has become a broader concern in the 21^st century. This study examines prevalence and incidence of anxiety and depression amongst student-athletes at the University of Louisville from 2019-2023 across different Sports Groups. The prevalence of anxiety was found to be 20.22% and risk of anxiety was 15.65%. The prevalence of depression was found to be 13.11% and risk of depression was 18.75%. Logistic regression was used to estimate the association between sports groups and anxiety/depression. There was a borderline association between sports groups and prevalence of anxiety after confounder adjustment (OR=1.86, 95% CI: …

Useful Measures Of Adult Attachment And Object Relations In Psychotherapy, Matilde A. Torallas Huerta

Dissertations

This is a literature review of objective and projective measures of attachment and object relations in adults, with the objective of reviewing outstanding research to identify the key factors for adult attachment assessment considered within attachment and object relations theories, what measures of adult attachment styles and dysfunction work best, and to provide key themes of assistance in the measurement of attachment and object relations in adult clients in psychotherapy. Theoretical foundations of attachment and object relations theory are reviewed as well as objective and projective instruments grouped by format. The 10 themes found to be useful in the assessment …

Maternal Dysbiosis Produces Long-Lasting Behavioral Changes In Offspring, Jacob Hudobenko, Claudia M Di Gesù, Patrick R Mooz, Joseph Petrosino, Nagireddy Putluri, Bhanu P Ganesh, Kristen Rebeles, Frank W Blixt, Venugopal R Venna, Louise D Mccullough

Faculty, Staff and Student Publications

Advanced maternal age (AMA) is defined as a pregnancy in a woman older than 35 years of age. AMA increases the risk for both maternal and neonatal complications, including miscarriage and stillbirth. AMA has also been linked to neurodevelopmental and neuropsychiatric disorders in the offspring. Recent studies have found that age-associated compositional shifts in the gut microbiota contribute to altered microbial metabolism and enhanced inflammation in the host. We investigated the specific contribution of the maternal microbiome on pregnancy outcomes and offspring behavior by recolonizing young female mice with aged female microbiome prior to pregnancy. We discovered that pre-pregnancy colonization …

Investigating Prefrontal Cortex Neuronal Signatures Of Opioid-Induced Risk-Taking Behavior, Cana Quave

Dissertations and Theses (Open Access)

Opioid use disorder occurs alongside impaired risk-related decision-making, but the underlying neural correlates are unclear. We developed an approach-avoidance conflict task using a modified conditioned place preference procedure to study neural signals of risky opioid seeking in the prefrontal cortex, a region implicated in executive decision-making. Following morphine conditioned place preference, rats underwent a conflict test in which fear-inducing cat odor was introduced in the previously drug-paired side of the apparatus. While the saline-exposed control group avoided cat odor, the morphine group included two subsets of rats that either maintained a preference for the paired side despite the presence of …

Investigating The Role Of The Hypocretin/Orexin System In A Novel Model Of Polysubstance Dependence, Tyler Zarin

Electronic Theses and Dissertations

Substance use disorders (SUD) in the United States are steadily increasing. Potent and dangerous substances such as methamphetamine (MA) and fentanyl (FEN) are often co-used as a polysubstance (POLY), either intentionally or unknowingly as FEN is a common adulterant. SUD is characterized by physiological and psychological dependence involving the negative reinforcement of anhedonia and withdrawal which drive hypermotivated drug-taking behaviors. Current theory suggests that recruitment of hypocretin/orexin (HCRT) neuropeptide in reward and stress associated brain regions contributes to drug dependence. Despite strong evidence for HCRT’s role in mono-drug dependence, a relevant model for POLY dependence has yet to be developed, …

#Helpplz: Mental Health Representation In Theatre For Young Audiences, Kate Elizabeth Dirrigl

Theses and Dissertations

#HELPPLZ is a play for young theater audiences that depicts four teenagers with various mental health challenges. It’s target audience is for children ages ten to fifteen and should be performed by actors of similar ages. #HELPPLZ is an immersive theatre experience, as a audience members watch four actors perform from four different lifestyles and point of views, all while broadcast on screens behind the actors. Every seat is a good seat in the house. This play follows a shift in trends of mental health depiction in contemporary theatre. No longer demonized and much more accessible, plays such as Dear …

An Examination Of The Role Of Recreational Therapy In Forensic And Correctional Settings, Sarah R. Fischer

All Dissertations

The estimated prevalence of adults, age 18 and older, with serious mental illness (SMI) in the United States is approximately 6% (NIMH, 2022a). Having a mental illness places individuals at higher risk for arrest and incarceration (NAMI, n.d.b) where they receive treatment, including recreational therapy (RT) in state hospitals, jails or prisons. The purpose of this multi-method study was to gain a better understanding of the role of RT in treating adults with SMI in forensic and correctional settings. A non-standardized 122-item cross-sectional survey (n=49) was used to identify what interventions recreational therapists are using, for what intended outcomes; and …

A Comprehensive Literature Review Of Barriers And Facilitators To Alcohol Use Disorder Screening And Treatment, Lizette M. Orihuela

Capstone Experience: Master of Public Health

Background: Alcohol Use Disorder (AUD) remains a significant public health issue with extensive personal, societal, and economic impacts. Recent studies indicate that no amount of alcohol consumption is entirely safe, linking it directly to increased chronic disease risks, including cancer. Despite well-documented negative health outcomes, clear guidance on what constitutes AUD through diagnostic criteria provided by the DSM-5, AUD continues to be underdiagnosed and undertreated.

Objectives: This comprehensive literature review explores the key barriers and facilitators influencing AUD screening and treatment engagement.

Methods: A comprehensive literature review was conducted, gathering from various databases including, PubMed, PsycINFO, Scopus, Google Scholar, and …