Mental and Social Health Commons^™

Mortality Risks Associated With Depression In Men With Prostate Cancer, Casey Crump, Pär Stattin, James D Brooks, Jan Sundquist, Weiva Sieh, Kristina Sundquist

Faculty, Staff and Student Publications

Background: Men diagnosed with prostate cancer (PC) have an increased risk of depression; however, it is unclear to what extent depression affects long-term survival. A better understanding of such effects is needed to improve long-term care and outcomes for men with PC.

Objective: To determine the associations between major depression and mortality in a national cohort of men with PC.

Design, setting, and participants: A national cohort study was conducted of all 180 189 men diagnosed with PC in Sweden during 1998-2017. Subsequent diagnoses of major depression were ascertained from nationwide outpatient and inpatient records through 2018.

Outcome measurements and …

Understanding The Association Between Neighborhoods And Adolescent Sleep: Evidence From Add Health, Sam J Neally, Breanna J P Rogers, Yangyang Deng, Mohammad Moniruzzaman, Qian Xiao, Kosuke Tamura

Faculty, Staff and Student Publications

INTRODUCTION: Research suggests that perceived neighborhood social environments (PNSE) may contribute to gender and race/ethnicity-based sleep disparities. Our study aimed to examine associations between PNSE factors and adolescents' sleep patterns. As a secondary aim, we examined how gender and race/ethnic groups might moderate these associations.

METHOD: Data came from the National Longitudinal Study of Adolescent to Adult Health (n=5158; mean age=15.34 years). Four self-reported sleep outcomes were created: 1) sleep duration (hours/night), 2) short sleep (≥8 hours [reference] vs <8 >hours), 3) parental set bedtime (10:00 PM/earlier [reference] among girls vs by 11:00PM vs by/after 12:00AM), and 4) sleep satisfaction (enough …

The Impact Of Elder Abuse Training On Subacute Health Providers And Older Adults: Study Protocol For A Randomized Control Trial, Marina G. Cavuoto, Simona Markusevska, Catriona Stevens, Patricia Reyes, Gianna Renshaw, Micah D.J. Peters, Briony Dow, Peter Feldman, Andrew Gilbert, Elizabeth Manias, Duncan Mortimer, Joanne Enticott, Claudia Cooper, Josefine Antoniades, Brenda Appleton, Sigrid Nakrem, Meghan O’Brien, Joan Ostaszkiewicz, Marion Eckert, Cheryl Durston, Bianca Brijnath

Research outputs 2022 to 2026

Background: Elder abuse often goes unreported and undetected. Older people may be ashamed, fearful, or otherwise reticent to disclose abuse, and many health providers are not confident in asking about it. In the No More Shame study, we will evaluate a co-designed, multi-component intervention that aims to improve health providers’ recognition, response, and referral of elder abuse. Methods: This is a single-blinded, pragmatic, cluster randomised controlled trial. Ten subacute hospital sites (i.e. clusters) across Australia will be allocated 1:1, stratified by state to a multi-component intervention comprising a training programme for health providers, implementation of a screening tool and use …

Family Members’ Experiences With Depression Through The Lens Of Frank's Illness Narratives, Amanda Cole, Julie Ann Pooley, Lisa Whitehead

Research outputs 2022 to 2026

Background: Depression impacts around 300 million people worldwide and places significant strain on families who care for relatives with chronic mental health conditions. This strain can lead to substantial burdens and affect the mental health and well-being of family members. Aim: This study explores family members’ experiences with depression through the lens of Frank's illness narratives. Methods: Employing a narrative inquiry approach, interviews were conducted with eight family members of adults diagnosed with major depressive disorder. The data were analysed through the lens of Frank's illness narratives. Findings: Family members’ experiences revealed a complex interplay of narratives that reflected the …

Prevalence And Management Of Depressive Symptoms In Coronary Heart Disease Patients And Relationship With Cardiovascular Prognosis: A Prospective Cohort Study, Yewei Pan, Yequn Chen, Shenglin Wu, Pengxiang Ying, Zishan Zhang, Xuerui Tan, Jinxiu Zhu

Research outputs 2022 to 2026

Aims: Depressive symptoms are comorbid with coronary heart disease (CHD). There is a controversial debate about whether screening and intervention for depressive symptoms could improve cardiovascular prognosis. This study characterizes the prevalence, characteristics, cardiovascular prognosis and management need of depressive symptoms among CHD patients. Methods: CHD patients were recruited between November 18, 2020 and November 26, 2021. Depressive symptoms were evaluated with the Patient Health Questionnaire (PHQ-9). During the 12-month follow-up, cardiovascular disease (CVD) was the endpoint. Time-to-event data were estimated by Kaplan-Meier curves and Cox models. Results: Of 582 patients (25% women), 21.0% had mild depressive symptoms, and 7.5% …

Protocol To Implement And Evaluate A Culturally Secure, Strength-Based, Equine-Assisted Learning Program, "Yawardani Jan-Ga" (Horses Helping), To Support The Social And Emotional Wellbeing Of Australian Aboriginal Children And Young People, Juli Coffin, Sharmila Vaz, Cheryl Kickett-Tucker, Helen Milroy, Craig Olsson, Meg Kirby, Lesley Nelson, Rob Mcphee, Donna Cross

Research outputs 2022 to 2026

Australian Aboriginal people experience stressors from inequalities across crucial social determinants, including deep and entrenched disadvantage and exclusion. The impact of unaddressed historical issues is pervasive and intergenerational. The disproportionate rates of Aboriginal youth suicide, juvenile detention and imprisonment highlight the inadequacy of existing social and emotional wellbeing programs and services for Aboriginal children and young people. There is increasing recognition in Australia that aligning social and emotional wellbeing interventions with Western values and conceptions of mental health is one of the main barriers to service uptake among Aboriginal people. This suggests fundamental questions remain unanswered about what type of …

Genome-Derived Ampullary Adenocarcinoma Classifier And Postresection Prognostication, Brett L Ecker, Kenneth Seier, Austin M Eckhoff, Gabriella N Tortorello, Peter J Allen, Vinod P Balachandran, Nicola Blackburn, Michael I D'Angelica, Ronald P Dematteo, Daniel G Blazer, Jeffrey A Drebin, William E Fisher, Danielle Fortuna, Anthony J Gill, Marie-Claude Gingras, T Peter Kingham, Major K Lee, Michael E Lidsky, Daniel P Nussbaum, Michael J Overman, Jaswinder S Samra, Ronglai Shen, Carlie S Sigel, Kevin C Soares, Charles M Vollmer, Alice C Wei, Sabino Zani, Robert E Roses, Mithat Gonen, William R Jarnagin

Faculty, Staff and Students Publications

Importance: Ampullary adenocarcinoma (AA) is characterized by clinical and genomic heterogeneity. A previously developed genomic classifier defined biologically distinct phenotypes with greater accuracy than standard histologic classification. External validation is needed before routine clinical use.

Objective: To test external validity of the prognostic value of the hidden genome classifier of AA.

Design, setting, and participants: This retrospective cohort study took place at 6 international academic institutions. Consecutive patients (n = 192) who underwent curative-intent resection of histologically confirmed AA were included. The data were analyzed from January 2005 through July 2020.

Exposures: The multilevel meta-feature regression model previously trained on …

Guidelines For The Standardization Of Pre-Analytical Variables For Salivary Biomarker Studies In Alzheimer's Disease Research: An Updated Review And Consensus Of The Salivary Biomarkers For Dementia Research Working Group, Ted K. S. Ng, Chinedu Momoh, Mei-Ann Lim, Helena Sophia Gleerup, Wayne Leifert, Catherine Ajalo, Nicholas Ashton, Henrik Zetterberg, Robert A. Rissman, Charisse N. Winston

Brain and Mind Institute

There is a pressing need for accessible biomarkers with high diagnostic accuracy for Alzheimer's disease (AD) diagnosis to facilitate widespread screening, particularly in underserved groups. Saliva is an emerging specimen for measuring AD biomarkers, with distinct contexts of use that could complement blood and cerebrospinal fluid and detect various analytes. An interdisciplinary, international group of AD and related dementias (ADRD) researchers convened and performed a narrative review of published studies on salivary AD biomarkers. We critically appraised the current state of the literature, examining both consistencies and discrepancies in existing pre-analytical variables and methodologies. We discussed how various pre-analytical variables …

Effectiveness Of Interventions To Address Nursing Students' Mental Health: An Integrative Review, Aimee Dickson, Shelby Carter

Master's Projects

Background:

The rigors of the nursing school curriculum are associated with higher levels of stress, anxiety, and depression, resulting in unhealthy habits and ineffective coping strategies that lead to initial difficulties in the academic environment and burnout as professional nurses advance into their careers. This phenomenon further burdens the already taxed workforce, leading to ongoing turnover and compromising care. This integrative review aims to look at what coping strategies have proven most successful in fostering nursing students' well-being, leading to lifelong practices that promote strength while addressing the rigors of academia and, later, the workforce.

Methods:

The literature review search …

Exploring Alternative Treatments For Acute Exacerbations Of Cannabis Hyperemesis Syndrome In Patients Who Plan To Continue Using Cannabis, Tabitha E H Moses

Clinical Research in Practice: The Journal of Team Hippocrates

A clinical decision report using:

Dean DJ, Sabagha N, Rose K, et al. A Pilot Trial of Topical Capsaicin Cream for Treatment of Cannabinoid Hyperemesis Syndrome. Acad Emerg Med. 2020;27(11):1166-1172. https://doi.org/10.1111/acem.14062

for a patient with cannabis hyperemesis syndrome.

The Refractive Thinker® Vol. Xxiv Mental Health: Chapter 9: Triage For Mental Health: Faculty’S Role And Assessment, Cheryl Lentz, Dr. Karen Balcanoff, Dr. Cherri Brown

Publications

The public knows about the importance of triage in the hospital emergency setting, but few are aware of this term in institutions of higher learning. Triage is simply matching students with priority order of resources most needed (Merriam Webster, 2023). Faculty can be the first line of defense or first responders in the classroom to provide students the help they need before escalation ensues. The focus of this article was to review the need for additional faculty training to ensure professors are part of students’ “network of care” (Sarraf, 2021). Disruptive student behavior is easy to detect in the classroom …

The Brain Initiative Data-Sharing Ecosystem: Characteristics, Challenges, Benefits, And Opportunities, Sudhanvan Iyer, Kathryn Maxson Jones, Jill O Robinson, Nicole R Provenza, Dominique Duncan, Gabriel Lázaro-Muñoz, Amy L Mcguire, Sameer A Sheth, Mary A Majumder

Faculty, Staff and Students Publications

In this paper, we provide an overview and analysis of the BRAIN Initiative data-sharing ecosystem. First, we compare and contrast the characteristics of the seven BRAIN Initiative data archives germane to data sharing and reuse, namely data submission and access procedures and aspects of interoperability. Second, we discuss challenges, benefits, and future opportunities, focusing on issues largely specific to sharing human data and drawing on N = 34 interviews with diverse stakeholders. The BRAIN Initiative-funded archive ecosystem faces interoperability and data stewardship challenges, such as achieving and maintaining interoperability of data and archives and harmonizing research participants’ informed consents for …

Study Abroad Angst: A Literature Review On The Mental Health Of International Students During Covid-19, Daisuke Akiba, Michael Perrone, Caterina Almendral

Publications and Research

Background: The COVID-19 pandemic presented unique and unprecedented challenges for international students, those studying at institutions of higher education outside of their home countries, due to their distinct circumstances and vulnerabilities. This literature review examines the multifaceted mental health burdens they experienced and highlights the need for targeted support and interventions. Methods: A rigorous search across three databases (i.e., PubMed, PsycINFO, and ERIC) yielded 50 empirical studies for inclusion in this literature review. A six-phase thematic analysis framework was employed to identify and synthesize key themes. Results: Seven prominent themes emerged: (1) academic and professional disruptions; (2) challenges navigating international …

Modulation Of Energetic And Lipid Pathways By Curcumin As A Potential Chemopreventive Strategy In Human Prostate Cancer Cells, Michele Pellegrino, Maria Antonietta Occhiuzzi, Fedora Grande, Ilaria Stefania Pagani, Stefano Aquaro, Paola Tucci

Staff and Researcher Publications

In Western industrialized countries, prostate cancer (PCa) is the second most common malignant disease and prevalent cause of death for men. Epidemiological studies have shown that curcumin (CUR) either prevents PCa initiation or delays its progression to a more aggressive and treatment-refractory form, thus reducing related mortality. Our previous studies have proven the anticancer, antioxidant, and anti-inflammatory properties of CUR on PCa cells. However, there are few reports of the effect of CUR on energy and lipid pathways in PCa. Herein, we show that CUR can modulate the two metabolic energy pathways, increasing glycolytic reserve and reducing oxidative phosphorylation. Moreover, …

Difficult To Treat Depression: Focus On Approach, Algorithms, And Access, Jordan F Karp, Roberta D Brinton, Jay C Fournier, Lisa Harding, Manish K Jha, Eric J Lenze, Sanjay J Mathew, Samantha Meltzer-Brody, David C Mohr, Patricio Riva-Posse, Ilse Wiechers, Nolan R Williams

Staff and Researcher Publications

The pandemic refocused interest on the burden of depression across the lifespan; the increased efforts to prevent and treat depression are now a priority of health care systems, insurers, patient advocates, digital therapeutic engineers, telemedicine platforms, and community health agencies. However, the challenges of treating depression to remission in adult patients who do not respond to first, second, or third levels of oral pharmacotherapy remain. The increased prevalence of these conditions is at odds with the shrinking psychiatric workforce. Since addressing difficult to treat depression is situated in a rapidly evolving treatment landscape, The University of Arizona College of Medicine-Tucson …

Using High-Frequency Oscillations From Brief Intraoperative Neural Recordings To Predict The Seizure Onset Zone, Behrang Fazli Besheli, Zhiyi Sha, Jay R Gavvala, Sacit Karamursel, Michael Quach, Chandra Prakash Swamy, Amir Hossein Ayyoubi, Alica M Goldman, Daniel J Curry, Sameer A Sheth, David Darrow, Kai J Miller, David J Francis, Gregory A Worrell, Thomas R Henry, Nuri F Ince

Faculty, Staff and Students Publications

BACKGROUND: While high-frequency oscillations (HFOs) and their stereotyped clusters (sHFOs) have emerged as potential neuro-biomarkers for the rapid localization of the seizure onset zone (SOZ) in epilepsy, their clinical application is hindered by the challenge of automated elimination of pseudo-HFOs originating from artifacts in heavily corrupted intraoperative neural recordings. This limitation has led to a reliance on semi-automated detectors, coupled with manual visual artifact rejection, impeding the translation of findings into clinical practice.

METHODS: In response, we have developed a computational framework that integrates sparse signal processing and ensemble learning to automatically detect genuine HFOs of intracranial EEG data. This …

Administration Patterns Of Magnesium Sulphate For Women With Preeclampsia And Immediate Newborn Outcomes In Kawempe National Referral Hospital-Uganda: A Cohort Study, Christopher J. Burant, Shirley Moore, Carol Blixen, Martha Sajatovic

Faculty Scholarship

Background: Preeclampsia is the second leading cause of maternal death in Uganda. WHO recommends using magnesium sulphate (MgSO4) to prevent and treat preeclampsia with severe features (PEC) and eclampsia. MgSO4 is used to prevent eclampsia and treat women who experience an eclamptic convulsion to avoid severe maternal/infant illnesses and death. We set out to assess MgSO4 administration patterns in women with PEC or eclampsia and the immediate newborn outcomes of neonates. Methods: This was an analytical observational cohort study at Kawempe National Referral Hospital in Uganda. Two hundred ten pregnant mothers with PEC or eclampsia were recruited in the study …

Evaluating Trauma-Informed Design In A Mental Health Setting: A Community-Based Research Case Study, Marie Spence

Electronic Theses and Dissertations

This case study utilized a community-based research framework to explore how the Trauma-Informed Design framework can be implemented in a mental health setting. This study focused on the site of Empower Therapy Practice, a private mental health practice in the Denver Metro Area, to engage clients and staff to participate in advisory boards and inform the interior design of a new office space. To explore the application of Trauma-Informed Design, participants engaged in a variety of research activities, including an evaluative questionnaire, Photovoice, and focus group. Advisory board members identified various aspects of Trauma-Informed Design which meaningfully translate to therapeutic …

Factors Related To Racial Trauma Distress Among Bipoc College Students, Miguel Castano, Richard Chang, Giezel Guevarra

Undergraduate Research Symposium Posters

Racial trauma distress is when post-traumatic stress disorder symptoms occur due to repeated and cumulative experiences of racism and can negatively impacted Black, Indigenous, and people of color (BIPOC). Consensus in research findings strongly suggest that BIPOC students are more likely to experience racism on university campuses than non-BIPOC students. To mitigate some of these negative outcomes, existing research has shown that psychological safety, resilience, and intraminority solidarity are protective factors for BIPOC students experiencing race-related distress. However, little is known about the frequency of racial trauma distress among BIPOC college students and how these variables may protect against racial …

Alternatives To Screen Time Given In Parenting Advice, Emma Romeo

Undergraduate Research Symposium Lightning Talks

Screen time within the last decade is an area of rising interest, especially in a "Post-Covid" world. Despite a diversity of opinions being written and research being done on screen time, what is being presented as an alternative is lesser known. In this research, the aim is to identify types of activities that are presented to parents as alternatives' to screen time in parenting websites and blogs. This study uses qualitative content analysis of over 240 articles from 2019-2023 mentioning media use or screen time from two regularly consumed and popular parenting websites, Sheknows.com and Parents.com. The data so far …

The Impact Of Intimate Partner Violence On Young Mother's Mental Health, Claudia Chavez, Clariana Vitória Ramos De Oliveira

Undergraduate Research Symposium Posters

Intimate partner violence (IPV) rates are notably higher among adolescents who are pregnant or have experienced a pregnancy, with physical IPV reaching up to 62%, and psychological abuse being even more common. IPV has serious mental health consequences for adolescent mothers, leading to increased rates of depression and anxiety which can impair caregiving. IPV negatively affects children, increasing the risks of poor maternal bonding, and low birth weight. This study investigates how IPV contributes to adverse mental health outcomes in Brazilian adolescent mothers. A cross-sectional approach was used with data collected between August 2023 to 2024. The study participants were …

The Relationship Between Gender And Experienes Of Weight Stigma From Healthcare Providers, Isabella J. Aceituno, Shannon Sagert

Undergraduate Research Symposium Posters

Healthcare providers are a common source of weight stigma, which is associated with lower physician trust, poorer patient outcomes, and the avoidance of healthcare services. Currently, there is a lack of consensus in research on whether women and men are equally likely to experience weight stigma from healthcare providers. The present study examined whether gender differences exist in weight stigma received from healthcare providers in childhood or adulthood, comfort seeking medical care, and healthcare avoidance. Adult participants (N = 196) reported the frequency at which they experienced stigmatizing experiences in healthcare environments in the past 12 months and during childhood …

"Screen Time" And The Perception Of It Among Different Social Classes, Jasmine Ayon

Undergraduate Research Symposium Posters

“Screen Time” and the subsequent demonization of it is a phenomenon that is not as analyzed through a social and comparative lens as much as psychological and health ones. To address this gap in research, we performed a content analysis on articles concerning families and “screen time” use that were published on two well-known parenting websites SheKnows and Parents.com from 2019 - 2022 (n = 220). In this paper, we address how these articles talk about screen time use among different social classes. In our analysis, we found what appears to be a double standard in the way screen time …

The Role Of Uncertainty In Illness: Insights Into Psychological Adjustment In Systemic Lupus Erythematosus, Theresa A. Skojec

MUSC Theses and Dissertations

There are currently few studies that directly explore the relationship between uncertainty in illness and psychological adjustment to Systemic Lupus Erythematosus (SLE), highlighting a critical gap in understanding how patients cope with and adjust to the emotional and mental challenges posed by this chronic condition. This dissertation comprises three manuscripts focused on filling this knowledge gap. The first is an integrative review guided by Mishel’s Uncertainty in Illness Theory, which examines how uncertainty affects patients' psychological and emotional well-being during illness and explores strategies to manage or reduce this uncertainty. The integrative review included 27 publications that examined uncertainty in …

Firearm Access, Carriage And Use In An Ethnically Diverse Sample Of Young Adults In Texas, Usa, Yu Lu, Elizabeth Baumler, Annalyn Saludares Demello, Leila Wood, Hillary Mcguire, Jeff R Temple

Faculty, Staff and Student Publications

Background Despite the high rates of firearm ownership and firearm-related injuries and mortalities in Southern US states, understandings on the factors contributing to these are lacking.

Methods Using wave 10 (2021) data from a longitudinal study, we examined firearm-related experiences among 636 ethnically diverse young adults (mean age=26 years; 62% female) in Texas, USA.

Results Just over half of participants had ready access to firearms, with 22.3% having carried a firearm outside of their home, 4.9% having been threatened with a firearm by a romantic partner and 4.4% by a non-romantic partner. More firearm access and carriage were reported in …

Fact Sheet For Parents: What You Need To Know About Adderall, Aaron Hunt, Gabriela Murza, Alyssa Ferrin

All Current Publications

This fact sheet provides information about what Adderall is used for, how it can be misused, and what parents can do to talk to their kids about appropriate use.

Enhancing Occupational Therapy Students’ Education In Animal-Assisted Therapy: Students’ Experience, Jessica Hill, Sophie Mensforth, Lucy Waldby, Jennifer Fleming, Teresa Quinlan, Carlie Driscoll

People and Animals: The International Journal of Research and Practice

Animal-assisted therapy has been gaining increased attention in occupational therapy practice and research. Yet the topic remains missing from university curricula at an international level. The aim of this study was to describe how animal-assisted therapy might be introduced to occupational therapy curricula and explore the experience of students who were able to implement their knowledge within a student-led clinic. Nine occupational therapy students engaged in individual semistructured interviews, allowing them to describe their experience participating in a student-led canine-assisted therapy clinic. Transcripts were analysed using inductive thematic analysis. Four themes emerged describing the students’ experience: outside my comfort zone, …

Nevada’S Care Workforce: Obstacles And Opportunities For Policymakers, David Damore, Caitlin J. Saladino, William E. Brown Jr., Fatma Nasoz

Policy Briefs and Reports

The care economy includes “the paid and unpaid labor and services that support caregiving in all its forms.” This work includes caring for children, the elderly, and those who are ill or have disabilities. Care work is often undervalued, underpaid, and without a fair system of work benefits in place (e.g. contracts, paid leave, workers’ rights) that in many cases falls disproportionately on women and communities of color. In this policy brief, we examine the care economy in Nevada by focusing on three areas of care: (1) child care; (2) elder care; and (3) mental and behavioral health care. In …

Downeast Community Opioid Response Program: Final Summary Report, Tyler Egeland Ba, Gordon Mcintire Ba, Evelyn Ali, Mary Lindsey Smith Phd, Katie Rosingana Ba

Substance Use Research & Evaluation

The Downeast Substance Treatment Network is a group of diverse organizations working to improve integration and access to treatments and services for people with substance use disorder. The consortium’s Rural Communities Opioid Response Program grant project aims to: (1) expand the reach of their treatment network, (2) increase awareness and practice of harm reduction, and (3) facilitate transitions of care to improve partner efficacy. This project included a mixed-methods evaluation led by Catherine E. Cutler Institute’s Substance Use Research and Evaluation Team (SURE). This year 3 final summary presentation includes feedback from program partners and key informants, in addition to …

Interprofessional Approach To Anxiety And Depression, John M. Sedrak, Benjamin Jones, Dominique Denbow, Ezra Aistrop-Gormley

CAIEP Fall Showcase 2024

A multidisciplinary approach for treating a patient from El Paso, Texas, with complex social and psychiatric challenges, including comorbid depression and anxiety. She faces limited access to resources, a sparse support system, and escalating social barriers. Environmental stressors, such as traffic pollution that exacerbates her asthma, and minimal community engagement further impact her mental health. An interprofessional care plan included mental health counseling, community outreach to enhance social support, and medical management to comprehensively address her interconnected health needs.