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Sarcopenia In Head And Neck Cancer: A Prognostic Analysis, Nedeljko Jovanovic
Sarcopenia In Head And Neck Cancer: A Prognostic Analysis, Nedeljko Jovanovic
Electronic Thesis and Dissertation Repository
Introduction: In head and neck cancer (HNC), loss of skeletal muscle mass (SMM), or sarcopenia, is a strong prognostic factor for outcomes. However, inconsistencies in its assessment limit our understanding of the relationship between sarcopenia and nutrition-related outcomes. This project evaluated the significance of sarcopenia as described in the literature and as demonstrated in a cohort of HNC patients.
Methods: A scoping review was first conducted followed by a retrospective cohort study with data collected from 194 oropharyngeal carcinoma patients treated with definitive radiation/chemoradiation. Sarcopenia was assessed from computed tomography (CT) imaging at the third cervical vertebra (C3) and the …