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2020

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Articles 541 - 570 of 640

Full-Text Articles in Pediatrics

Are Children With Sars-Cov-2 Infection At High Risk For Thrombosis? Viscoelastic Testing And Coagulation Profiles In A Case Series Of Pediatric Patients, M. Al-Ghafry, B. Aygun, A. Appiah-Kubi, A. Vlachos, G. Ostovar, C. Capone, T. Sweberg, N. Palumbo, P. Goenka, L. L. Wolfe, J. M. Lipton, S. S. Acharya Jan 2020

Are Children With Sars-Cov-2 Infection At High Risk For Thrombosis? Viscoelastic Testing And Coagulation Profiles In A Case Series Of Pediatric Patients, M. Al-Ghafry, B. Aygun, A. Appiah-Kubi, A. Vlachos, G. Ostovar, C. Capone, T. Sweberg, N. Palumbo, P. Goenka, L. L. Wolfe, J. M. Lipton, S. S. Acharya

Journal Articles

© 2020 Wiley Periodicals LLC The coagulopathy of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is well documented in adults, with increases in D-dimer and prothrombin time found to be strong predictors of mortality, and anticoagulation shown to decrease this mortality. Viscoelastic parameters such as elevations in maximum clot firmness (MCF) on rotational thromboelastometry (ROTEM) have correlated with a hypercoagulable state in adults with SARS-CoV-2. We report our experience in children infected with SARS-CoV-2, with noted elevations in D-dimer and MCF on ROTEM (indicating hypercoagulability). Exploration of viscoelastic testing to provide additional laboratory-based evidence for pediatric-specific risk assessment …

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Cardiac Dysfunction And Shock In Pediatric Patients With Covid-19., K. Joshi, D. Kaplan, A. Bakar, J. F. Jennings, D. A. Hayes, S. Mahajan, N. Misra, E. Mitchell, T. M. Sweberg, M. D. Taylor, C. A. Capone Jan 2020

Cardiac Dysfunction And Shock In Pediatric Patients With Covid-19., K. Joshi, D. Kaplan, A. Bakar, J. F. Jennings, D. A. Hayes, S. Mahajan, N. Misra, E. Mitchell, T. M. Sweberg, M. D. Taylor, C. A. Capone

Journal Articles

Coronavirus disease-2019 (COVID-19) has been reported to cause significant morbidity in adults, with reportedly a lesser impact on children. Cardiac dysfunction has only been described in adults thus far. We describe 3 cases of previously healthy children presenting with shock and COVID-19-related cardiac inflammation. (Level of Difficulty: Intermediate.).

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Covid-19 In Children: More Than Meets The Eye, Sh F. Hagmann Jan 2020

Covid-19 In Children: More Than Meets The Eye, Sh F. Hagmann

Journal Articles

No abstract provided.

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Covid-19 Outcomes In Ms Observational Study Of Early Experience From Nyu Multiple Sclerosis Comprehensive Care Center, E. Parrotta, I. Kister, L. Charvet, C. Sammarco, V. Saha, R. E. Charlson, J. Howard, J. M. Gutman, C. Fernandez-Carbonell, L. Z. Ryerson, +5 Additional Authors Jan 2020

Covid-19 Outcomes In Ms Observational Study Of Early Experience From Nyu Multiple Sclerosis Comprehensive Care Center, E. Parrotta, I. Kister, L. Charvet, C. Sammarco, V. Saha, R. E. Charlson, J. Howard, J. M. Gutman, C. Fernandez-Carbonell, L. Z. Ryerson, +5 Additional Authors

Journal Articles

No abstract provided.

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Predictors Of Gestational Weight Gain In A Low-Income Hispanic Population: Sociodemographic Characteristics, Health Behaviors, And Psychosocial Stressors, C. D. Dolin, R. S. Gross, A. L. Deierlein, L. T. Berube, M. Katzow, Y. Yaghoubian, S. G. Brubaker, M. J. Messito Jan 2020

Predictors Of Gestational Weight Gain In A Low-Income Hispanic Population: Sociodemographic Characteristics, Health Behaviors, And Psychosocial Stressors, C. D. Dolin, R. S. Gross, A. L. Deierlein, L. T. Berube, M. Katzow, Y. Yaghoubian, S. G. Brubaker, M. J. Messito

Journal Articles

No abstract provided.

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Safety And Tolerability Of Manual Push Administration Of Subcutaneous Igpro20 At High Infusion Rates In Patients With Primary Immunodeficiency: Findings From The Manual Push Administration Cohort Of The Hilo Study, J. Cowan, V. R. Bonagura, P. L. Lugar, P. J. Maglione, N. C. Patel, D. C. Vinh, J. H. Hofmann, M. Praus, M. A. Rojavin Jan 2020

Safety And Tolerability Of Manual Push Administration Of Subcutaneous Igpro20 At High Infusion Rates In Patients With Primary Immunodeficiency: Findings From The Manual Push Administration Cohort Of The Hilo Study, J. Cowan, V. R. Bonagura, P. L. Lugar, P. J. Maglione, N. C. Patel, D. C. Vinh, J. H. Hofmann, M. Praus, M. A. Rojavin

Journal Articles

© 2020, The Author(s). Purpose: To evaluate the safety and tolerability of IgPro20 manual push (also known as rapid push) infusions at flow rates of 0.5–2.0 mL/min. Methods: Patients with primary immunodeficiency (PID) with previous experience administering IgPro20 (Hizentra®, CSL Behring, King of Prussia, PA, USA) were enrolled in the Hizentra® Label Optimization (HILO) study (NCT03033745) and assigned to Pump-assisted Volume Cohort, Pump-assisted Flow Rate Cohort, or Manual Push Flow Rate Cohort; this report describes the latter. Patients administered IgPro20 via manual push at 0.5, 1.0, and 2.0 mL/min/site for 4 weeks each. Responder rates (percentage of patients who completed …

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Use Of Tetanus Toxoid, Reduced Diphtheria Toxoid, And Acellular Pertussis Vaccines: Updated Recommendations Of The Advisory Committee On Immunization Practices - United States, 2019, F. P. Havers, P. L. Moro, P. Hunter, S. Hariri, H. Bernstein Jan 2020

Use Of Tetanus Toxoid, Reduced Diphtheria Toxoid, And Acellular Pertussis Vaccines: Updated Recommendations Of The Advisory Committee On Immunization Practices - United States, 2019, F. P. Havers, P. L. Moro, P. Hunter, S. Hariri, H. Bernstein

Journal Articles

No abstract provided.

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A Modified Delphi Study To Prioritize Content For A Simulation-Based Pediatric Curriculum For Emergency Medicine Residency Training Programs, J. Mitzman, I. Bank, R. A. Burns, M. C. Nguyen, P. Zaveri, M. J. Falk, M. Madhok, A. Dietrich, F. M. Bullaro, M. Auerbach, +9 Additional Authors Jan 2020

A Modified Delphi Study To Prioritize Content For A Simulation-Based Pediatric Curriculum For Emergency Medicine Residency Training Programs, J. Mitzman, I. Bank, R. A. Burns, M. C. Nguyen, P. Zaveri, M. J. Falk, M. Madhok, A. Dietrich, F. M. Bullaro, M. Auerbach, +9 Additional Authors

Journal Articles

© 2019 by the Society for Academic Emergency Medicine Objectives: Pediatric training is an essential component of emergency medicine (EM) residency. The heterogeneity of pediatric experiences poses a significant challenge to training programs. A national simulation curriculum can assist in providing a standardized foundation of pediatric training experience to all EM trainees. Previously, a consensus-derived set of content for a pediatric curriculum for EM was published. This study aimed to prioritize that content to establish a pediatric simulation-based curriculum for all EM residency programs. Methods: Seventy-three participants were recruited to participate in a three-round modified Delphi project from 10 stakeholder …

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Brucella Exposure Risk Events In 10 Clinical Laboratories, New York City, Usa, 2015 To 2017, J. Ackelsberg, A. Liddicoat, T. Burke, W. A. Szymczak, M. H. Levi, B. Ostrowsky, E. A. Mitchell, W. Lowe, R. Khare, M. Layton, +34 Additional Authors Jan 2020

Brucella Exposure Risk Events In 10 Clinical Laboratories, New York City, Usa, 2015 To 2017, J. Ackelsberg, A. Liddicoat, T. Burke, W. A. Szymczak, M. H. Levi, B. Ostrowsky, E. A. Mitchell, W. Lowe, R. Khare, M. Layton, +34 Additional Authors

Journal Articles

Copyright © 2020 American Society for Microbiology. All Rights Reserved. From 2015 to 2017, 11 confirmed brucellosis cases were reported in New York City, leading to 10 Brucella exposure risk events (Brucella events) in 7 clinical laboratories (CLs). Most patients had traveled to countries where brucellosis is endemic and presented with histories and findings consistent with brucellosis. CLs were not notified that specimens might yield a hazardous organism, as the clinicians did not consider brucellosis until they were notified that bacteremia with Brucella was suspected. In 3 Brucella events, the CLs did not suspect that slow-growing, small Gram-negative bacteria might …

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Expert Opinion: Proposed Diagnostic And Treatment Algorithms For Lennox-Gastaut Syndrome In Adult Patients, G. Montouris, S. Aboumatar, D. Burdette, S. Kothare, R. Kuzniecky, W. Rosenfeld, S. Chung Jan 2020

Expert Opinion: Proposed Diagnostic And Treatment Algorithms For Lennox-Gastaut Syndrome In Adult Patients, G. Montouris, S. Aboumatar, D. Burdette, S. Kothare, R. Kuzniecky, W. Rosenfeld, S. Chung

Journal Articles

No abstract provided.

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Gaps In Allergen Immunotherapy Administration And Subcutaneous Allergen Immunotherapy Dose Adjustment Schedules Need For Prospective Data, D. E. Larenas-Linnemann, T. Epstein, P. Ponda, D. Bernstein, P. Williams, P. Creticos Jan 2020

Gaps In Allergen Immunotherapy Administration And Subcutaneous Allergen Immunotherapy Dose Adjustment Schedules Need For Prospective Data, D. E. Larenas-Linnemann, T. Epstein, P. Ponda, D. Bernstein, P. Williams, P. Creticos

Journal Articles

No abstract provided.

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How Adherent Are Obese Children With Sleep-Disordered Breathing On Positive Airway Pressure Therapy? Comment, S. V. Kothare, K. Kelly-Pieper Jan 2020

How Adherent Are Obese Children With Sleep-Disordered Breathing On Positive Airway Pressure Therapy? Comment, S. V. Kothare, K. Kelly-Pieper

Journal Articles

No abstract provided.

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Reporting Of Child Maltreatment During The Sars-Cov-2 Pandemic In New York City From March To May 2020, E. Rapoport, H. Reisert, E. Schoeman, A. Adesman Jan 2020

Reporting Of Child Maltreatment During The Sars-Cov-2 Pandemic In New York City From March To May 2020, E. Rapoport, H. Reisert, E. Schoeman, A. Adesman

Journal Articles

© 2020 Elsevier Ltd Background: School closures and other public health responses have decreased the extent that children interact with mandated reporters and other professionals trained to detect child maltreatment. Objective: To assess associations between the pandemic public health response and the number of allegations of child abuse or neglect. Methods: This study analyzed monthly data from New York City of the number of child maltreatment allegations, stratified by reporter type (e.g., mandated reporter, education personnel, healthcare personnel), as well as the number of Child Protective Services (CPS) investigations warranting child welfare preventative services. SARIMA models were trained using data …

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Role Of A Pediatric Cardiologist In The Covid-19 Pandemic, T. Niaz, K. Hope, M. Fremed, N. Misra, C. Altman, J. Glickstein, J. Sanchez-De-Toledo, A. Fraisse, J. Miller, D. Chowdhury, +2 Additional Authors Jan 2020

Role Of A Pediatric Cardiologist In The Covid-19 Pandemic, T. Niaz, K. Hope, M. Fremed, N. Misra, C. Altman, J. Glickstein, J. Sanchez-De-Toledo, A. Fraisse, J. Miller, D. Chowdhury, +2 Additional Authors

Journal Articles

© 2020, Springer Science+Business Media, LLC, part of Springer Nature. Coronavirus disease 2019 (COVID-19) has affected patients across all age groups, with a wide range of illness severity from asymptomatic carriers to severe multi-organ dysfunction and death. Although early reports have shown that younger age groups experience less severe disease than older adults, our understanding of this phenomenon is in continuous evolution. Recently, a severe multisystem inflammatory syndrome in children (MIS-C), with active or recent COVID-19 infection, has been increasingly reported. Children with MIS-C may demonstrate signs and symptoms of Kawasaki disease, but also have some distinct differences. These children …

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Central Apnea In An Adolescent With Covid-19, S Enner, S Hormozdyaran, R Varughese, J Milillo, I Pavkovic, E Laureta, J Schneider, S Kothare Jan 2020

Central Apnea In An Adolescent With Covid-19, S Enner, S Hormozdyaran, R Varughese, J Milillo, I Pavkovic, E Laureta, J Schneider, S Kothare

Journal Articles

No abstract provided.

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A Pediatric Patient With Sickle Cell Disease Presenting With Severe Anemia And Splenic Sequestration In The Setting Of Covid-19, S. Jacob, A. Dworkin, E. Romanos-Sirakis Jan 2020

A Pediatric Patient With Sickle Cell Disease Presenting With Severe Anemia And Splenic Sequestration In The Setting Of Covid-19, S. Jacob, A. Dworkin, E. Romanos-Sirakis

Journal Articles

No abstract provided.

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Immunotherapies For Covid-19: Lessons Learned From Sepsis, Ke Remy, Sc Brakenridge, B Francois, T Daix, Cs Deutschman, G Monneret, R Jeannet, Pf Laterre, Rs Hotchkiss, Ll Moldawer Jan 2020

Immunotherapies For Covid-19: Lessons Learned From Sepsis, Ke Remy, Sc Brakenridge, B Francois, T Daix, Cs Deutschman, G Monneret, R Jeannet, Pf Laterre, Rs Hotchkiss, Ll Moldawer

Journal Articles

No abstract provided.

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Pediatric Covid-19-Associated Rhabdomyolysis: A Case Report, Am Gefen, N Palumbo, Sk Nathan, Ps Singer, Lj Castellanos-Reyes, Cb Sethna Jan 2020

Pediatric Covid-19-Associated Rhabdomyolysis: A Case Report, Am Gefen, N Palumbo, Sk Nathan, Ps Singer, Lj Castellanos-Reyes, Cb Sethna

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No abstract provided.

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Altered Monocyte And Langerhans Cell Innate Immunity In Patients With Recurrent Respiratory Papillomatosis (Rrp), M. Israr, J. A. Devoti, F. Lam, A. L. Abramson, B. M. Steinberg, V. R. Bonagura Jan 2020

Altered Monocyte And Langerhans Cell Innate Immunity In Patients With Recurrent Respiratory Papillomatosis (Rrp), M. Israr, J. A. Devoti, F. Lam, A. L. Abramson, B. M. Steinberg, V. R. Bonagura

Journal Articles

No abstract provided.

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Cd4 T Follicular Helper Cells Prevent Depletion Of Follicular B Cells In Response To Cecal Ligation And Puncture, M. D. Taylor, M. R. Brewer, A. Nedeljkovic-Kurepa, Y. Yang, K. S. Reddy, M. N. Abraham, B. J. Barnes, C. S. Deutschman Jan 2020

Cd4 T Follicular Helper Cells Prevent Depletion Of Follicular B Cells In Response To Cecal Ligation And Puncture, M. D. Taylor, M. R. Brewer, A. Nedeljkovic-Kurepa, Y. Yang, K. S. Reddy, M. N. Abraham, B. J. Barnes, C. S. Deutschman

Journal Articles

No abstract provided.

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Comparison Of Artifacts Between Paste And Collodion Method Of Electrode Application In Pediatric Eeg, D. Brigham, Y. Shah, K. Singh, I. Pavkovic, S. Karkare, S. V. Kothare Jan 2020

Comparison Of Artifacts Between Paste And Collodion Method Of Electrode Application In Pediatric Eeg, D. Brigham, Y. Shah, K. Singh, I. Pavkovic, S. Karkare, S. V. Kothare

Journal Articles

© 2019 International Federation of Clinical Neurophysiology Objectives: Children pose challenges to obtain quality EEG data due to excessive artifact. Collodion is used in EEG electrodes due to its water resistance and strong adhesive qualities. This study was done to evaluate differences in artifacts between the collodion and paste method. Methods: 115 subjects (children age >3 years) were randomized into paste and collodion groups and artifacts evaluated at baseline and every hour over 30 s increments. Age, sleep state, and number of electrodes with artifact were also documented. T-test was performed to determine differences in the various parameters between the …

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Cost Of Survivorship Care And Adherence To Screening-Aligning The Priorities Of Health Care Systems And Survivors., C. Benedict, J. Wang, M. Reppucci, C. L. Schleien, J. D. Fish Jan 2020

Cost Of Survivorship Care And Adherence To Screening-Aligning The Priorities Of Health Care Systems And Survivors., C. Benedict, J. Wang, M. Reppucci, C. L. Schleien, J. D. Fish

Journal Articles

Childhood cancer survivors (CCS) experience significant morbidity due to treatment- related late effects and benefit from late-effects surveillance. Adherence to screening recommendations is suboptimal. Survivorship care programs often struggle with resource limitations and may benefit from understanding institution-level financial outcomes associated with patient adherence to justify programmatic development and growth. The purpose of this study is to examine how CCS adherence to screening recommendations relates to the cost of care, insurance status, and institution-level financial outcomes. A retrospective chart review of 286 patients, followed in a structured survivorship program, assessed adherence to the Children's Oncology Group follow-up guidelines by comparing …

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Demographics And Outcomes Of Patients With Eating Disorders Treated In Residential Care, M. Fisher, J. R. Henretty, S. A. Cox, R. Feinstein, V. Fornari, L. Moskowitz, M. Schneider, S. Levine, J. Malizio, J. Fishbein Jan 2020

Demographics And Outcomes Of Patients With Eating Disorders Treated In Residential Care, M. Fisher, J. R. Henretty, S. A. Cox, R. Feinstein, V. Fornari, L. Moskowitz, M. Schneider, S. Levine, J. Malizio, J. Fishbein

Journal Articles

No abstract provided.

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Early Oral Colostrum Administration In Preterm Infants, D. Maffei, M. Brewer, C. Codipilly, B. Weinberger, R. J. Schanler Jan 2020

Early Oral Colostrum Administration In Preterm Infants, D. Maffei, M. Brewer, C. Codipilly, B. Weinberger, R. J. Schanler

Journal Articles

No abstract provided.

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Evaluation And Management Of Overweight And Obesity In Children And Adolescents – Current Problems In Pediatric And Adolescent Health Care, J. Kerns, M. Fisher Jan 2020

Evaluation And Management Of Overweight And Obesity In Children And Adolescents – Current Problems In Pediatric And Adolescent Health Care, J. Kerns, M. Fisher

Journal Articles

No abstract provided.

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Gonococcal Osteomyelitis In A Pediatric Patient With Disseminated Gonococcal Infection: Implications For Antimicrobial Management, W. Liakos, B. Schaffler, S. Rajan, S. H. Hagmann Jan 2020

Gonococcal Osteomyelitis In A Pediatric Patient With Disseminated Gonococcal Infection: Implications For Antimicrobial Management, W. Liakos, B. Schaffler, S. Rajan, S. H. Hagmann

Journal Articles

© 2020 The Authors We report a case of a female teenager with gonococcal septic arthritis of the right shoulder that also caused osteomyelitis of the humeral head. Infection with Neisseria gonorrhoeae is a frequently diagnosed sexually transmitted infection in the sexually active teenage population and disseminated gonococcal infection (DGI) is the most common systemic manifestation of acute gonorrhea. DGI commonly involves acute arthritis, tenosynovitis and dermatitis with less common complications of endocarditis, hepatitis and meningitis. In contrast, osteomyelitis has only rarely been reported as a result of gonococcal infection. Clinicians need to be aware of this unusual manifestation of …

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Management Of Pediatric Systemic Lupus Erythematosus: Focus On Belimumab, M. Guzman, J. S. Hui-Yuen Jan 2020

Management Of Pediatric Systemic Lupus Erythematosus: Focus On Belimumab, M. Guzman, J. S. Hui-Yuen

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No abstract provided.

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Newborn Screening Protocols And Positive Predictive Value For Congenital Adrenal Hyperplasia Vary Across The United States, P. W. Speiser, R. Chawla, M. Chen, A. Diaz-Thomas, C. Finlayson, M. M. Rutter, D. E. Sandberg, K. Shimy, J. Cerise, E. C. Délot, +2 Additional Authors Jan 2020

Newborn Screening Protocols And Positive Predictive Value For Congenital Adrenal Hyperplasia Vary Across The United States, P. W. Speiser, R. Chawla, M. Chen, A. Diaz-Thomas, C. Finlayson, M. M. Rutter, D. E. Sandberg, K. Shimy, J. Cerise, E. C. Délot, +2 Additional Authors

Journal Articles

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). Newborn screening for congenital adrenal hyperplasia (CAH) caused by 21-hydroxylase deficiency is mandated throughout the US. Filter paper blood specimens are assayed for 17-hydroxyprogesterone (17OHP). Prematurity, low birth weight, or critical illness cause falsely elevated results. The purpose of this report is to highlight differences in protocols among US state laboratories. We circulated a survey to state laboratory directors requesting qualitative and quantitative information about individual screening programs. Qualitative …

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Use Of Organ Dysfunction As A Primary Outcome Variable Following Cecal Ligation And Puncture: Recommendations For Future Studies, M. N. Abraham, A. P. Kelly, A. B. Brandwein, T. D. Fernandes, D. E. Leisman, M. D. Taylor, M. R. Brewer, C. A. Capone, C. S. Deutschman Jan 2020

Use Of Organ Dysfunction As A Primary Outcome Variable Following Cecal Ligation And Puncture: Recommendations For Future Studies, M. N. Abraham, A. P. Kelly, A. B. Brandwein, T. D. Fernandes, D. E. Leisman, M. D. Taylor, M. R. Brewer, C. A. Capone, C. S. Deutschman

Journal Articles

Outcomes variables for research on sepsis have centered on mortality and changes in the host immune response. However, a recent task force (Sepsis-3) revised the definition of sepsis to "life-threatening organ dysfunction caused by a dysregulated host response to infection." This new definition suggests that human studies should focus on organ dysfunction. The appropriate criteria for organ dysfunction in either human sepsis or animal models are, however, poorly delineated, limiting the potential for translation. Further, in many systems, the difference between "dysfunction" and "injury" may not be clear. In this review, we identify criteria for organ dysfunction and/or injury in …

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Characteristics And Risk Factors Associated With Critical Illness In Pediatric Covid-19, G. Fisler, S. M. Izard, S. Shah, D. Lewis, M. K. Kainth, S. H. F. Hagmann, J. A. Belfer, L. M. Feld, F. Mastroianni, C. L. Kvasnovsky, C. A. Capone, J. Schneider, T. Sweberg, C. Schleien, M. D. Taylor Jan 2020

Characteristics And Risk Factors Associated With Critical Illness In Pediatric Covid-19, G. Fisler, S. M. Izard, S. Shah, D. Lewis, M. K. Kainth, S. H. F. Hagmann, J. A. Belfer, L. M. Feld, F. Mastroianni, C. L. Kvasnovsky, C. A. Capone, J. Schneider, T. Sweberg, C. Schleien, M. D. Taylor

Journal Articles

© 2020, The Author(s). Background: While much has been reported regarding the clinical course of COVID-19 in children, little is known regarding factors associated with organ dysfunction in pediatric COVID-19. We describe critical illness in pediatric patients with active COVID-19 and identify factors associated with PICU admission and organ dysfunction. This is a retrospective chart review of 77 pediatric patients age 1 day to 21 years admitted to two New York City pediatric hospitals within the Northwell Health system between February 1 and April 24, 2020 with PCR + SARS-CoV-2. Descriptive statistics were used to describe the hospital course and …

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