Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Pathology
Neuropsychological Outcomes In Adults Commencing Highly Active Anti-Retroviral Treatment In South Africa: A Prospective Study, John A. Joska, John A. Joska, Jennifer Westgarth-Taylor, Jacqueline Hoare, Kevin Gf Thomas, Robert Paul, Landon Myer, Dan J. Stein
Neuropsychological Outcomes In Adults Commencing Highly Active Anti-Retroviral Treatment In South Africa: A Prospective Study, John A. Joska, John A. Joska, Jennifer Westgarth-Taylor, Jacqueline Hoare, Kevin Gf Thomas, Robert Paul, Landon Myer, Dan J. Stein
Robert Paul
Background
Infection with HIV may result in significant neuropsychological impairment, especially in late stage disease. To date, there have been no cohort studies of the impact of highly active anti-retroviral treatment (HAART) in South Africa where clade C HIV is predominant.
Methods
Participants in the current study were recruited from a larger study of HIV-associated neurocognitive disorders (HAND) and included a group of individuals commencing HAART (n = 82). Baseline and one-year neuropsychological function was assessed using a detailed battery, and summary global deficit scores (GDS) obtained. Associations with change in GDS were calculated.
Results
Participants had a median CD4 …