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Neonatal Reference Intervals For Thyroid Stimulating Hormone And Free Thyroxine Assayed On A Siemens Atellica® Im Analyzer: A Cross Sectional Study, Geoffrey Omuse, David Kawalya, Patrick Mugaine, Assumpta Chege, Daniel Maina
Neonatal Reference Intervals For Thyroid Stimulating Hormone And Free Thyroxine Assayed On A Siemens Atellica® Im Analyzer: A Cross Sectional Study, Geoffrey Omuse, David Kawalya, Patrick Mugaine, Assumpta Chege, Daniel Maina
Pathology, East Africa
Background Deriving population specific reference intervals (RIs) or at the very least verifying any RI before adoption is good laboratory practice. Siemens has provided RIs for thyroid stimulating hormone (TSH) and free thyroxine (FT4) determined on their Atellica® IM analyzer for all age groups except the neonatal age group which provides a challenge for laboratories that intend to use it to screen for congenital hypothyroidism (CH) and other thyroid disorders in neonates. We set out to determine RIs for TSH and FT4 using data obtained from neonates undergoing routine screening for CH at the Aga Khan University Hospital, Nairobi, Kenya. …