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Articles 1 - 9 of 9
Full-Text Articles in Pathology
Performance Evaluation Of The Luminex Aries® C. Difficile Assay In Comparison To Two Other Molecular Assays Within A Multi-Hospital Health Care Center., S. Juretschko, R. Manji, R. Khare, S. Das, S. Dunbar
Performance Evaluation Of The Luminex Aries® C. Difficile Assay In Comparison To Two Other Molecular Assays Within A Multi-Hospital Health Care Center., S. Juretschko, R. Manji, R. Khare, S. Das, S. Dunbar
Journal Articles
Clostridioides difficile infections (CDI) remain a serious issue in the U.S. Both fast and accurate diagnosis of CDI is paramount to achieve immediate infection control initiation, triaging and isolation, as well as appropriate antibiotic treatment. However, both, over- and under-diagnosis can lead to adverse patient outcomes, such as unnecessary administration of antibiotics or unwanted spread of spores in any hospital setting, respectively. In this prospective study, we evaluated the FDA-cleared ARIES® C. difficile Assay and compared its performance and workflow characteristics to the BD MAX Cdiff and Xpert C.difficile/Epi assays. Out of 302 samples tested, 55 (18.2%) samples were positive, …
Systemic P-Anca Vasculitis With Fatal Outcome, Arising In The Setting Of Methimazole Use., S. Hacking, N. N. Uppal, N. Khan, M. Ionescu, V. Bijol
Systemic P-Anca Vasculitis With Fatal Outcome, Arising In The Setting Of Methimazole Use., S. Hacking, N. N. Uppal, N. Khan, M. Ionescu, V. Bijol
Journal Articles
Here we report a fatal case of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) due to methimazole use in a 64-year-old woman. She was initially hospitalized for abdominal pain and possible colitis, and subsequently developed hematuria, renal failure, and hemoptysis. The serologic work-up revealed positive antinuclear antibody (ANA) and perinuclear-antineutrophilic cytoplasm antibodies (p-ANCA), with positive antimyeloperoxidase. Three weeks following admission, the patient was found to be pulseless, and expired. At autopsy, microscopic review included widespread transmural necrotizing vasculitis and crescentic glomerulonephritis in the kidney, and diffuse pulmonary alveolar hemorrhage; focal coronary artery intimal vasculitis and necrotizing pericarditis were also noted. Several …
Differentiating Noninvasive Follicular Thyroid Neoplasm With Papillary-Like Nuclear Features From Classic Papillary Thyroid Carcinoma: Analysis Of Cytomorphologic Descriptions Using A Novel Machine-Learning Approach., S. Maleki, A. Zandvakili, S. Gera, S. D. Khutti, A. Gersten, S. N. Khader
Differentiating Noninvasive Follicular Thyroid Neoplasm With Papillary-Like Nuclear Features From Classic Papillary Thyroid Carcinoma: Analysis Of Cytomorphologic Descriptions Using A Novel Machine-Learning Approach., S. Maleki, A. Zandvakili, S. Gera, S. D. Khutti, A. Gersten, S. N. Khader
Journal Articles
Background:Recent studies show various cytomorphologic features that can assist in the differentiation of classic papillary thyroid carcinoma (cPTC) from noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP). Differentiating these two entities changes the clinical management significantly. We evaluated the performance of support vector machine (SVM), a machine learning algorithm, in differentiating cases of NIFTP and encapsulated follicular variant of papillary thyroid carcinoma with no capsular or lymphovascular invasion (EFVPTC) from cases of cPTC with the use of microscopic descriptions. SVM is a supervised learning algorithm used in classification problems. It assigns the input data to one of two categories …
Primary Follicular Lymphoma Of The Bladder Mimicking Inflammatory Condition: Case Report And Review Of The Literature, N. Haghi, X. Zhang, J. Kreshover
Primary Follicular Lymphoma Of The Bladder Mimicking Inflammatory Condition: Case Report And Review Of The Literature, N. Haghi, X. Zhang, J. Kreshover
Journal Articles
© 2019 The Authors Primary lymphoma of the bladder is rare and may present with nonspecific symptoms and infection. Primary follicular lymphoma of the bladder is extremely rare with only a dozen reported cases. We present one case clinically mimicking an inflammatory process. A 79 year-old woman presents with recurrent urinary tract infections, urinary incontinence and frequency. Cystoscopic examination demonstrated a raised but flat lesion, suspicious for inflammatory lesion. Biopsy revealed a diagnosis of follicular lymphoma, grade 1–2. The presentation of primary follicular lymphoma of the bladder may be nonspecific, therefore it is important to consider this diagnosis in patients …
Comparison Of The Panther Fusion And Bd Max Gbs Assays For Detection Of Group B Streptococcus In Prenatal Screening Specimens., G. J. Berry, F. Zhang, R. Manji, S. Juretschko
Comparison Of The Panther Fusion And Bd Max Gbs Assays For Detection Of Group B Streptococcus In Prenatal Screening Specimens., G. J. Berry, F. Zhang, R. Manji, S. Juretschko
Journal Articles
Streptococcus agalactiae, or Group B Streptococcus (GBS) is the cause of early and late-onset GBS disease in neonates and can present as septicemia, meningitis, and pneumonia. Our objective was to compare the performance of two FDA-approved nucleic acid amplification tests (NAATs), the Panther Fusion and BD MAX™ systems, for detection of group B Streptococcus (GBS) in vaginal-rectal screening specimens. A total of 510 vaginal-rectal prepartum specimens were tested simultaneously in both NAATs following broth enrichment. Assay agreement was calculated using the kappa statistics. Overall agreement between assays was 99.0% (505/510; 95% CI: 0.951 to 0.997; kappa = 0.974). Discordant results …
A Comparison Of Daxx (Death Domain Associated Protein 6) In Different Endometrial Carcinoma Histotypes, C. Jin, S. Hacking, M. K. Komforti, M. Nasim
A Comparison Of Daxx (Death Domain Associated Protein 6) In Different Endometrial Carcinoma Histotypes, C. Jin, S. Hacking, M. K. Komforti, M. Nasim
Journal Articles
No abstract provided.
Familial Inheritance Of The 3q29 Microdeletion Syndrome: Case Report And Review, W. A. Khan, N. Cohen, S. A. Scott, E. M. Pereira
Familial Inheritance Of The 3q29 Microdeletion Syndrome: Case Report And Review, W. A. Khan, N. Cohen, S. A. Scott, E. M. Pereira
Journal Articles
No abstract provided.
The Conscientious Autopsy., A. K. Williamson
Practical Guidance For Clinical Microbiology Laboratories: Viruses Causing Acute Respiratory Tract Infections, C. L. Charlton, E. Babady, C. C. Ginocchio, T. F. Hatchette, R. C. Jerris, Y. Li, M. Loeffelholz, Y. S. Mccarter, M. B. Miller, S. J. Drews, +4 Additional Authors
Practical Guidance For Clinical Microbiology Laboratories: Viruses Causing Acute Respiratory Tract Infections, C. L. Charlton, E. Babady, C. C. Ginocchio, T. F. Hatchette, R. C. Jerris, Y. Li, M. Loeffelholz, Y. S. Mccarter, M. B. Miller, S. J. Drews, +4 Additional Authors
Journal Articles
No abstract provided.