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Articles 1 - 7 of 7
Full-Text Articles in Pathology
Cytogenomic Identification And Long-Read Single Molecule Real-Time (Smrt) Sequencing Of A Bardet-Biedl Syndrome 9 (Bbs9) Deletion, J. Reiner, L. Pisani, W. Qiao, R. Singh, Y. Yang, L. Shi, W. A. Khan, R. Sebra, N. Cohen, S. A. Scott, +3 Additional Authors
Cytogenomic Identification And Long-Read Single Molecule Real-Time (Smrt) Sequencing Of A Bardet-Biedl Syndrome 9 (Bbs9) Deletion, J. Reiner, L. Pisani, W. Qiao, R. Singh, Y. Yang, L. Shi, W. A. Khan, R. Sebra, N. Cohen, S. A. Scott, +3 Additional Authors
Journal Articles
No abstract provided.
Overexpression Of Β1 Integrin Contributes To Polarity Reversal And A Poor Prognosis Of Breast Invasive Micropapillary Carcinoma, B. Liu, X. Zheng, F. Meng, Y. Han, Y. Song, F. Liu, S. Li, L. Zhang, X. Zhang, L. Fu, +1 Additional Author
Overexpression Of Β1 Integrin Contributes To Polarity Reversal And A Poor Prognosis Of Breast Invasive Micropapillary Carcinoma, B. Liu, X. Zheng, F. Meng, Y. Han, Y. Song, F. Liu, S. Li, L. Zhang, X. Zhang, L. Fu, +1 Additional Author
Journal Articles
© Liu et al. Invasive micropapillary carcinoma (IMPC) of the breast is a highly aggressive breast cancer. Polarity reversal exemplified by cluster growth is hypothesized to contribute to the invasiveness and metastasis of IMPC. In this study, we demonstrate that levels of β1 integrin and Rac1 expression were greater in breast IMPC than in invasive breast carcinoma of no specific type and paraneoplastic benign breast tissue. We show that silencing β1 integrin expression using the β1 integrin inhibitor AIIB2 partially restored polarity in IMPC primary cell clusters and downregulated Rac1. Thus, overexpression of β1 integrin upregulates Rac1. Univariate analysis showed …
A Primary Breast Cancer With Distinct Foci Of Estrogen Receptor-Alpha Positive And Negative Cells Derived From The Same Clonal Origin As Revealed By Whole Exome Sequencing, K. Kyker-Snowman, B. Erlanger Avigdor, M. Nasim, A. Cimino-Mathews, S. J. Wheelan, P. Argani, B. H. Park
A Primary Breast Cancer With Distinct Foci Of Estrogen Receptor-Alpha Positive And Negative Cells Derived From The Same Clonal Origin As Revealed By Whole Exome Sequencing, K. Kyker-Snowman, B. Erlanger Avigdor, M. Nasim, A. Cimino-Mathews, S. J. Wheelan, P. Argani, B. H. Park
Journal Articles
© 2018, Springer Science+Business Media, LLC, part of Springer Nature. Background/purpose: Tumor heterogeneity is a now well-recognized phenomenon that can affect the classification, prognosis and treatment of human cancers. Heterogeneity is often described in primary breast cancers based upon histologic subtypes, hormone- and HER2-receptor status, and immunolabeling for various markers, which can be seen within a single tumor as mixed cellular populations, or as separate discrete foci. Experimental design/methods: Here, we present a case report of a patient’s primary breast cancer that had two separate but adjacent histologic components, one that was estrogen receptor (ER) positive, and the other ER …
Stromal Infiltration Of Tumor-Associated Macrophages Conferring Poor Prognosis Of Patients With Basal-Like Breast Carcinoma, M. Yang, Z. Li, M. Ren, S. Li, L. Zhang, X. Zhang, F. Liu
Stromal Infiltration Of Tumor-Associated Macrophages Conferring Poor Prognosis Of Patients With Basal-Like Breast Carcinoma, M. Yang, Z. Li, M. Ren, S. Li, L. Zhang, X. Zhang, F. Liu
Journal Articles
© Ivyspring International Publisher. Aims: Tumor associated macrophages (TAMs) play a critical role in the initiation and progression of breast cancer. However, their prognostic significance in the molecular subtype of basal-like breast cancer (BLBC) is poorly understood. The aim of this study was to investigate the extent and patterns of TAMs in BLBC and their associations with clinicopathological features and patient survival. Methods and Results: We evaluated TAMs in 200 cases of BLBC by immunohistochemistry using the M2 macrophage marker CD163 and the pan-macrophage marker CD68 in tumor nest and stroma, and assessed their prognostic significance. The study demonstrated that …
Phosphoglycerate Mutase 1 Is Highly Expressed In C6 Glioma Cells And Human Astrocytoma, Z. Liu, J. Ding, C. Du, N. Xu, E. Wang, J. Li, Y. Wang, J. Yu
Phosphoglycerate Mutase 1 Is Highly Expressed In C6 Glioma Cells And Human Astrocytoma, Z. Liu, J. Ding, C. Du, N. Xu, E. Wang, J. Li, Y. Wang, J. Yu
Journal Articles
No abstract provided.
Automated Real-Time Collection Of Pathogen-Specific Diagnostic Data: Syndromic Infectious Disease Epidemiology, L. Meyers, C. C. Ginocchio, A. N. Faucett, F. S. Nolte, P. H. Gesteland, A. Leber, D. Janowiak, V. Donovan, S. Juretschko, M. A. Poritz, +23 Additional Authors
Automated Real-Time Collection Of Pathogen-Specific Diagnostic Data: Syndromic Infectious Disease Epidemiology, L. Meyers, C. C. Ginocchio, A. N. Faucett, F. S. Nolte, P. H. Gesteland, A. Leber, D. Janowiak, V. Donovan, S. Juretschko, M. A. Poritz, +23 Additional Authors
Journal Articles
© Lindsay Meyers, Christine C Ginocchio, Aimie N Faucett, Frederick S Nolte, Per H Gesteland, Amy Leber, Diane Janowiak,. Background: Health care and public health professionals rely on accurate, real-time monitoring of infectious diseases for outbreak preparedness and response. Early detection of outbreaks is improved by systems that are comprehensive and specific with respect to the pathogen but are rapid in reporting the data. It has proven difficult to implement these requirements on a large scale while maintaining patient privacy. Objective: The aim of this study was to demonstrate the automated export, aggregation, and analysis of infectious disease diagnostic test …
Pleural Effusion In A 7-Year-Old Child - With Unique Cells, N. Gupta, K. Das
Pleural Effusion In A 7-Year-Old Child - With Unique Cells, N. Gupta, K. Das
Journal Articles
No abstract provided.