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Full-Text Articles in Pathology
Immunohistochemistry For The Proliferation Markers Ki67 And Phh3 In Cell Block Material Of Basaloid Salivary Gland Neoplasms Is Predictive Of Malignancy, Robert Post, Zach Breslin, Yanki Yarman, Stacey Gargano
Immunohistochemistry For The Proliferation Markers Ki67 And Phh3 In Cell Block Material Of Basaloid Salivary Gland Neoplasms Is Predictive Of Malignancy, Robert Post, Zach Breslin, Yanki Yarman, Stacey Gargano
Department of Pathology, Anatomy, and Cell Biology Posters
Background: Basaloid salivary gland neoplasms (BSGNs) are notoriously difficult to classify in fine needle aspiration (FNA) specimens due to the morphologic overlap shown by the various benign and malignant entities in this category1,2,3. Adenoid cystic carcinoma (AdCC) represents a particular diagnostic challenge, as it typically shows low grade cytologic features despite its aggressive clinical behavior and need for more extensive surgery4. We examined whether the proliferation markers Ki67 and PHH3 could help predict malignancy in BSGNs, thus improving diagnostic accuracy and optimizing patient care.