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Comparison Of Five Different Serological Assays For Determination Of Antibody Levels Against Herpes Virus Type 1 And 2, Murat Sami Küçük
Comparison Of Five Different Serological Assays For Determination Of Antibody Levels Against Herpes Virus Type 1 And 2, Murat Sami Küçük
Loma Linda University Electronic Theses, Dissertations & Projects
To aid in the diagnosis of certain clinical types of Herpes virus infections, we evaluated and compared five serological methods for measuring Herpes virus antibody. The five tests we compared are complement fixation test (CF), indirect immunofluorescent antibody assay (IFA), anticomplementary immunofluorescent assay (ACIF), enzyme linked immunoassay test (ELISA), and the latex agglutination test (LA). The main objective of this study was to establish which of the currently available serologic tests was best suited for clinical laboratory use and which may then replace the complement fixation test. In the comparative testing, one hundred twenty serum samples were divided into four …