Open Access. Powered by Scholars. Published by Universities.®

Ophthalmology Commons™

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 3 of 3

Full-Text Articles in Ophthalmology

Mobility Task Shows Rescue Of Scotopic Vision In A Swine Model For Autosomal Dominant Retinitis Pigmentosa After Treatment With The Meganuclease Rho 1-2, Gita Jaikumar, Jack Feist, Kautuk Kamboj, Aravind Kumar, Francesca Barone, Archana Jalligampala, Wei Wang, Jeff Smith, Dave Morris, Derek Jantz, Victor Bartsevich, Kristi Viles, Maureen Mccall Jan 2025

Mobility Task Shows Rescue Of Scotopic Vision In A Swine Model For Autosomal Dominant Retinitis Pigmentosa After Treatment With The Meganuclease Rho 1-2, Gita Jaikumar, Jack Feist, Kautuk Kamboj, Aravind Kumar, Francesca Barone, Archana Jalligampala, Wei Wang, Jeff Smith, Dave Morris, Derek Jantz, Victor Bartsevich, Kristi Viles, Maureen Mccall

Posters-at-the-Capitol

Purpose : Retinitis pigmentosa (RP) is the most common form of inherited retinal disease with ~1:5000 people affected worldwide. The substitution of Proline to Histidine (P23H) at position 23 in the rhodopsin protein is the most common form of adRP in North America. We have shown that treating a transgenic P23H human RHO pig model of adRP (TgP23H hRHO) with a gene-editing meganuclease Rho 1-2, recovers rod structure and restores rod function. We ran WT, Rho1-2 treated and untreated TgP23H hRHO (Tg) pigs through an obstacle course to quantify visually guided mobility under light- and dark-adapted conditions using motion analysis …


Combination Of Topical Tacrolimus, Antioxidants, And Probiotics In The Treatment Of Periorbital Vitiligo, Ali Chaudhry May 2022

Combination Of Topical Tacrolimus, Antioxidants, And Probiotics In The Treatment Of Periorbital Vitiligo, Ali Chaudhry

St. Chris Research Day

No abstract provided.


Unilateral Olfactory Thresholds In A Chemosensory Clinic Population, Beverly Cowart, Edmund Pribitkin, David Rosen, Christopher Klock, Timothy Laflam Apr 2004

Unilateral Olfactory Thresholds In A Chemosensory Clinic Population, Beverly Cowart, Edmund Pribitkin, David Rosen, Christopher Klock, Timothy Laflam

Department of Otolaryngology - Head and Neck Surgery Faculty Papers

Poster presentation at 26th Annual Meeting of the Association of Chemoreception Sciences in Sarasota Florida, April 21-25, 2004.

INTRODUCTION

Because there is the possibility of unilateral loss of olfactory function or differential degrees of olfactory dysfunction in the two nostrils, unilateral tests of olfactory threshold sensitivity are routinely included in many chemosensory clinical test batteries to supplement bilateral tests (e.g., Cain et al., 1988; Hummel et al., 1997). Surprisingly, however, the results of unilateral testing in patients with chemosensory complaints have not been extensively reported. Thus, it is unclear how useful these additional measures are in characterizing individual patients.

A …