Open Access. Powered by Scholars. Published by Universities.®

Oncology Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 4 of 4

Full-Text Articles in Oncology

Oncolog Volume 53 Number 12, December 2008, Stephanie P. Deming, Virginia M. Mohlere Dec 2008

Oncolog Volume 53 Number 12, December 2008, Stephanie P. Deming, Virginia M. Mohlere

OncoLog MD Anderson's Report to Physicians (All issues)

  • Mantle Cell Lymphoma
  • Sparing the Nipple During Mastectomy
  • House Call: Taking Medicine? Be Aware of Food-Drug Interactions


Nerve Growth Factor Regulation Of Cyclin D1 In Pc12 Cells Through A P21ras Extracellular Signal-Regulated Kinase Pathway Requires Cooperative Interactions Between Sp1 And Nuclear Factor-Kappab., Francesco Marampon, Mathew C Casimiro, Maofu Fu, Michael J Powell, Vladimir M Popov, Jaime Lindsay, Bianca M Zani, Carmela Ciccarelli, Genichi Watanabe, Richard J Lee, Richard G Pestell Jun 2008

Nerve Growth Factor Regulation Of Cyclin D1 In Pc12 Cells Through A P21ras Extracellular Signal-Regulated Kinase Pathway Requires Cooperative Interactions Between Sp1 And Nuclear Factor-Kappab., Francesco Marampon, Mathew C Casimiro, Maofu Fu, Michael J Powell, Vladimir M Popov, Jaime Lindsay, Bianca M Zani, Carmela Ciccarelli, Genichi Watanabe, Richard J Lee, Richard G Pestell

Department of Cancer Biology Faculty Papers

The PC12 pheochromocytoma cell line responds to nerve growth factor (NGF) by exiting from the cell cycle and differentiating to induce extending neurites. Cyclin D1 is an important regulator of G1/S phase cell cycle progression, and it is known to play a role in myocyte differentiation in cultured cells. Herein, NGF induced cyclin D1 promoter, mRNA, and protein expression via the p21(RAS) pathway. Antisense- or small interfering RNA to cyclin D1 abolished NGF-mediated neurite outgrowth, demonstrating the essential role of cyclin D1 in NGF-mediated differentiation. Expression vectors encoding mutants of the Ras/mitogen-activated protein kinase pathway, and chemical inhibitors, demonstrated NGF …


Oncolog Volume 53, Number 04, April 2008, Diane Witter, John Lebas, Sunni Hosemann Jan 2008

Oncolog Volume 53, Number 04, April 2008, Diane Witter, John Lebas, Sunni Hosemann

OncoLog MD Anderson's Report to Physicians (All issues)

  • Cancer as a Chronic Disease
  • In Brief: Cancer-Promoting Protein in Ovarian Cancer May Be Stopped with RNA Liposome
  • House Call: Caring for the Caregiver
  • Barely Benign


Oncolog Volume 53, Number 02, February 2008, Joe Munch, Diane Witter, Guillermo Garcia-Manero Md Jan 2008

Oncolog Volume 53, Number 02, February 2008, Joe Munch, Diane Witter, Guillermo Garcia-Manero Md

OncoLog MD Anderson's Report to Physicians (All issues)

  • Assessing Symptom Burden in Cancer
  • DiaLog: Making Headway in Hematology, by Guillermo Garcia-Manero, MD, Associate Professor, Department of Leukemia
  • Helping Kids Make Smart Food Choices
  • Expanding Therapy Options for Advanced Cancer