Open Access. Powered by Scholars. Published by Universities.®
- Discipline
- Keyword
-
- Acute Myeloid Leukemia (1)
- Autophagy (1)
- Cancer (1)
- Cancer Survivors (1)
- Cisplatin (1)
-
- ERAS (1)
- ESP (1)
- Enhanced recovery after surgery (1)
- Erector spinae plane block (1)
- Head (1)
- Hepatectomy (1)
- Killer Immunoglobulin Like Receptors (1)
- Matched Unrelated Donor Transplant (1)
- Medicine (1)
- Neck (1)
- Open hepatectomy (1)
- Opioid Use (1)
- Radiation Oncology (1)
- Relapse (1)
- Senescence (1)
- Veteran (1)
- Veteran population (1)
- Publication
- Publication Type
Articles 1 - 5 of 5
Full-Text Articles in Oncology
A Mathematical Model To Explore The Potential Of Combinations Of Adt And Immunotherapies, Johnna Barnaby
A Mathematical Model To Explore The Potential Of Combinations Of Adt And Immunotherapies, Johnna Barnaby
Biology and Medicine Through Mathematics Conference
No abstract provided.
Selecting The Optimal Unrelated Hematopoietic Stem Cell Transplant Donor For Relapse Prevention In Acute Myeloid Leukemia, Elizabeth Krieger, Rehan Qayyum, Amir Toor
Selecting The Optimal Unrelated Hematopoietic Stem Cell Transplant Donor For Relapse Prevention In Acute Myeloid Leukemia, Elizabeth Krieger, Rehan Qayyum, Amir Toor
Graduate Medical Education (GME) Resident and Fellow Research Day Posters
Introduction/Background
Hematopoietic cell transplantation (HCT) provides
a cure for patients with acute myeloid leukemia.
Natural killer cells (NK) play an important role
in graft versus leukemia (GVL) effect after HCT,
through killer immunoglobulin-like receptor (KIR)
interaction with HLA ligands. This study is
undertaken to validate our previously published
mathematical model accounting for the KIR-KIRL
interactions in a post HCT setting.
Methods
Retrospective data were obtained from the Center
for International Blood and Marrow Transplant
Registry for 2317 donor recipient pairs (DRP) who
underwent 7/8 or 8/8 HLA allelic matched
unrelated donor (URD) HCT for AML. KIR-HLA
interaction scores were calculated …
The Effects Of Autophagy And Senescence On Sensitivity To Cisplatin In Head And Neck Cancer, Zara H. Siddiqui
The Effects Of Autophagy And Senescence On Sensitivity To Cisplatin In Head And Neck Cancer, Zara H. Siddiqui
Theses and Dissertations
While current treatments in cancer, such as chemotherapy and radiation, can generally be effective in eliminating disease in patients, there also exists the possibility of recurrence of cancer cells over time. In patients diagnosed with locally advanced head and neck carcinoma, about 50-60% develop a loco-regional recurrence within two years, and 20-30% of patients develop metastatic disease at distant sites in the body [5]. On a cellular level, one mechanism for this survival may be that natural mechanisms such as autophagy and senescence play a role in allowing cells to survive after undergoing treatment. One standard of care chemotherapy for …
New Persistent And Chronic Opioid Use In Cancer Survivors After Curative Intent Radiation, Elena V. Fernández
New Persistent And Chronic Opioid Use In Cancer Survivors After Curative Intent Radiation, Elena V. Fernández
Theses and Dissertations
Background: Emerging evidence suggests that as more patients are surviving cancer, new persistent opioid use (no prior exposure to opioids before cancer therapy but requiring opioid prescriptions after curative intent treatment; NPOU) is of greater concern. In patients receiving curative intent radiation (definitive radiation therapy and as treatment for cure; CIR), the extent to which patients develop NPOU or continue opioid use (COU) following CIR is not known. Neither are factors associated with NPOU or COU, opioid doses, or time to discontinuation (TTD) of opioids in 5CS known. Objectives: Describe longitudinal trends opioid use in cancer survivors who received CIR, …
Reduced Length Of Stay In Major Hepatectomy Surgery After Implementation Of An Enhanced Recovery Pathway In The United States Veteran Population, Yvonne Nguyen Md, Marilyn Mcnulty Np, Leopoldo Fernandez Md, Michael R. Kazior Md
Reduced Length Of Stay In Major Hepatectomy Surgery After Implementation Of An Enhanced Recovery Pathway In The United States Veteran Population, Yvonne Nguyen Md, Marilyn Mcnulty Np, Leopoldo Fernandez Md, Michael R. Kazior Md
Graduate Medical Education (GME) Resident and Fellow Research Day Posters
Introduction
Enhanced recovery after surgery (ERAS) pathways are associated with better postoperative recovery, however, evidence is lacking in major liver surgery, .This study aimed to evaluate the impact of an ERAS pathway in U.S. veterans undergoing major hepatectomy surgery. We hypothesized that the adoption of an ERAS pathway reduces decreased length of stay (LOS).
Methods
After approval from the Hunter Holmes McGuire VA Medical Center IRB, we compared data from consecutive patients undergoing elective open hepatectomy within an ERAS pathway (January 2019-December 2019) to a previous cohort of patients before introduction of ERAS (July 2016-December 2017). One surgeon performed all …