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Full-Text Articles in Oncology
Psychological Impact Of Comprehensive Tumor Genomic Profiling Results For Advances Cancer Patients, Phyllis N. Butow, Megan Best, Grace Davies, Timothy Schlub, Christine Napier, Nicci Bartley, Mandy Ballinger, Ilona Juraskova, Bettina Meiser, David Goldstein, Barbara Biesecker, David Thomas
Psychological Impact Of Comprehensive Tumor Genomic Profiling Results For Advances Cancer Patients, Phyllis N. Butow, Megan Best, Grace Davies, Timothy Schlub, Christine Napier, Nicci Bartley, Mandy Ballinger, Ilona Juraskova, Bettina Meiser, David Goldstein, Barbara Biesecker, David Thomas
IES Papers and Journal Articles
Objective
Comprehensive tumor genomic profiling (CTGP) is increasingly used to personalize treatments, providing hope, but potentially disappointment, for patients. We explored psychological outcomes in patients with advanced, incurable cancer, after receiving CTGP results.
Methods
Participants with advanced, incurable cancer (n = 560, mean age 56, 43% university educated) in this longitudinal substudy of the Molecular Screening and Therapeutics Program (MoST), completed questionnaires before and after receiving CGP results. MoST participants, recruited from Australian oncology clinics, undergo CTGP, and if there are actionable findings, are offered treatment in a related therapeutic trial if available.
Results
Patients who received actionable results, (n …