Oncology Commons^™

Can Ginger Ameliorate Chemotherapy-Induced Nausea? Protocol Of A Randomized Double Blind, Placebo-Controlled Trial, Wolfgang Marx, A Mccarthy, Karin Reid, Luis Vitetta, D Mckavanagh, Damien Thomson, Avni Sali, Elizabeth Isenring

Liz Isenring

Background: Preliminary research shows ginger may be an effective adjuvant treatment for chemotherapy-induced nausea and vomiting but significant limitations need to be addressed before recommendations for clinical practice can be made. Methods/Design: In a double–blinded randomised-controlled trial, chemotherapy-naïve patients will be randomly allocated to receive either 1.2 g of a standardised ginger extract or placebo per day. The study medication will be administrated as an adjuvant treatment to standard anti-emetic therapy and will be divided into four capsules per day, to be consumed approximately every 4 hours (300 mg per capsule administered q.i.d) for five days during the first three …