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Full-Text Articles in Oncology
Characterization Of Mouse Prostate Tumor-Infiltrating Leukocytes, Daniel Alan Holterman
Characterization Of Mouse Prostate Tumor-Infiltrating Leukocytes, Daniel Alan Holterman
Theses and Dissertations in Biomedical Sciences
Prostate cancer is the most common form of non-cutaneous cancer among men in the United States and the second most common cause of cancer-related death among men with approximately 189,000 new cases diagnosed and 30,200 deaths of the disease in 2002. Prostate cancer can be a treatable disease but once it becomes metastatic there are no acceptable therapies. For this reason, immunotherapy has been attempted but the results have been disappointing. The TRAMP model was used to evaluate specific interactions between an intact murine immune system and a prostate tumor that expressed a naturally processed weak tumor antigen. Vaccination trials …