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Full-Text Articles in Obstetrics and Gynecology
Randomized Trial Of Erythromycin And Azithromycin For Treatment Of Chlamydial Infection In Pregnancy., M F Rosenn, G A Macones, N S Silverman
Randomized Trial Of Erythromycin And Azithromycin For Treatment Of Chlamydial Infection In Pregnancy., M F Rosenn, G A Macones, N S Silverman
Department of Obstetrics and Gynecology Faculty Papers
OBJECTIVE: The purpose of this study was to compare erythromycin and azithromycin in the treatment of chlamydial cervicitis during pregnancy with regard to efficacy, side effects, and compliance.
METHODS: In a prospective manner, 48 pregnant patients with cervical chlamydial infections diagnosed by routine screening tests were randomly assigned to receive either erythromycin, 500 mg q.i.d. for 7 days (N = 24), or azithromycin, 1 g as a one-time dose (N = 24). All sexual partners were given prescriptions for doxycycline, 100 mg b.i.d. for 7 days. The treatment efficacy was assessed by follow-up chlamydia testing 3 weeks after the therapy …