Geriatrics Commons^™

Micrornas (Mirnas) In Neurodegenerative Diseases, Peter T. Nelson, Wang-Xia Wang, Bernard W. Rajeev

Sanders-Brown Center on Aging Faculty Publications

Aging-related neurodegenerative diseases (NDs) are the culmination of many different genetic and environmental influences. Prior studies have shown that RNAs are pathologically altered during the inexorable course of some NDs. Recent evidence suggests that microRNAs (miRNAs) may be a contributing factor in neurodegeneration. miRNAs are brain-enriched, small (~22 nucleotides) non-coding RNAs that participate in mRNA translational regulation. Although discovered in the framework of worm development, miRNAs are now appreciated to play a dynamic role in many mammalian brain-related biochemical pathways, including neuroplasticity and stress responses. Research about miRNAs in the context of neurodegeneration is accumulating rapidly, and the goal of …

Graduating "Seniors" Of Center In The Park's Harvest Health Program

CenterPieces

"I have been to many health classes but none like this. This class was great and well organized."

"When I wake up I start exercising in bed. The Harvest Health classes have motivated me. I am now exercising 6 days a week."

"I use a motorized wheelchair, and I walk only a few steps. Thanks to the support from my classmates and the instructors, I achieved my action plan and am now walking in the corridor at Center in the Park. The program has motivated me to achieve my goals."

These are the accolades that Project Director Delores Palmer hears …

Conference Brochure: 7th Annual Demential Management Conference

Center for Applied Research on Aging and Health Conferences

No abstract provided.

Ageing – The Independent Risk Indicator, Saba Sohail

Department of Radiology

No abstract provided.

Health Promotion For Older Adults: What Is The Potential?, Linda P. Fried

Center for Policy Research

As a greater number of people reach old age, medicine is challenged to develop new approaches to this population. Health promotion, not just treatment of disease but improving the quality of life for older persons, must play a role. What happens to individuals in terms of health status as they get older, and what are the implications for health care needs? Where should we focus to get the biggest benefits in terms of health promotion? Overall, we have learned a tremendous amount over the last 25 years about the components of health as people get older, and what modifies their …

The Hidden Age Revolution: Emergent Integration Of All Ages, Matilda White Riley

Center for Policy Research

Over the past 30 years my colleagues and I have been focusing on conceptual and empirical work (the aging and society paradigm) that does not create policies, but can inform them. The most immediate phase of this long cumulative history is leading us now to hidden changes in people's lives and social institutions that herald a new phenomenon world-wide--a phenomenon that may have momentous implications for the policies of the future. We call it "age integration" because it *integrates* older people with others of every age. When I come to the end of my lecture, I hope you will see …

American Longevity: Past, Present, And Future, Samuel H. Preston

Center for Policy Research

How long we live, and how long members of our families and social groups live, is extraordinarily important to us. It's not a subject of daily discussion, but it would be if we were threatened with a return to earlier conditions. Unfortunately, the subject of longevity falls between the cracks of academe and has received far less attention than it warrants. We are all aware, at least dimly, that people are living longer than they used to. The numbers are impressive: at the turn of the century, life expectancy at birth in the United States was 48 years; it's now …

Ethnicity And Lifetimes: Self Concepts And Situational Contexts Of Ethnic Identity In Late Life, Mark Luborsky, Robert L. Rubinstein

Anthropology Faculty Research Publications

This chapter reports on finding from a study of ethnic older men, aged 65 an older (Jewish, Irish, and Italian) who were widowed from 2 to 8 years after a long-term study. It focuses on life reorganization after the initial bereavement period. It identifies key issues in the process concerning continuity and change in identity reformulation, changes in health and activity patterns, ethnic identity and lingering attachment to the deceased spouse. Ethnicity as a dynamic life course process, shaped by contextual and historical dimensions, and personal meaning processes are highlighted. Supported by NIH# R01-AG005204